NO994902L - Forebygging av brystkreft ved selektive östrogenreseptormodulatorer - Google Patents
Forebygging av brystkreft ved selektive östrogenreseptormodulatorerInfo
- Publication number
- NO994902L NO994902L NO994902A NO994902A NO994902L NO 994902 L NO994902 L NO 994902L NO 994902 A NO994902 A NO 994902A NO 994902 A NO994902 A NO 994902A NO 994902 L NO994902 L NO 994902L
- Authority
- NO
- Norway
- Prior art keywords
- breast cancer
- estrogen receptor
- receptor modulators
- selective estrogen
- cancer prevention
- Prior art date
Links
- 206010006187 Breast cancer Diseases 0.000 title abstract 3
- 208000026310 Breast neoplasm Diseases 0.000 title abstract 3
- 230000002265 prevention Effects 0.000 title 1
- 239000000333 selective estrogen receptor modulator Substances 0.000 title 1
- 229940095743 selective estrogen receptor modulator Drugs 0.000 title 1
- -1 pyrrolidino, methylpyrrolidino, dimethylpyrrolidino, piperidino, morpholino Chemical group 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 201000008275 breast carcinoma Diseases 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/64—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4311897P | 1997-04-09 | 1997-04-09 | |
| PCT/US1998/006989 WO1998045286A1 (en) | 1997-04-09 | 1998-04-07 | Prevention of breast cancer with selective estrogen receptor modulators |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO994902D0 NO994902D0 (no) | 1999-10-08 |
| NO994902L true NO994902L (no) | 1999-12-07 |
Family
ID=21925594
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO994902A NO994902L (no) | 1997-04-09 | 1999-10-08 | Forebygging av brystkreft ved selektive östrogenreseptormodulatorer |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP0975628A4 (id) |
| JP (1) | JP2001518897A (id) |
| KR (1) | KR20010006215A (id) |
| CN (1) | CN1259945A (id) |
| AU (1) | AU6957398A (id) |
| CA (1) | CA2286207A1 (id) |
| EA (1) | EA199900910A1 (id) |
| HU (1) | HUP0001845A2 (id) |
| ID (1) | ID23653A (id) |
| IL (1) | IL132279A0 (id) |
| NO (1) | NO994902L (id) |
| PL (1) | PL336206A1 (id) |
| TR (1) | TR199903244T2 (id) |
| WO (1) | WO1998045286A1 (id) |
| ZA (1) | ZA982818B (id) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6653479B1 (en) | 1999-07-29 | 2003-11-25 | Eli Lilly And Company | Crystalline form of 6-hydroxy-3-(4-[2-(piperidin-1-yl)ethoxy]phenoxy)-2-(4-methoxyphenyl)benzo[b] thiophene hydrochloride |
| US6610706B1 (en) | 1999-07-29 | 2003-08-26 | Eli Lilly And Company | Crystalline form of 6-hydroxy-3-(4-[2-(piperidin-1-yl)ethoxy]phenoxy)-2-(4-methoxyphenyl)benzo[b]thiophene hydrochloride |
| SG185311A1 (en) | 2007-10-16 | 2012-11-29 | Repros Therapeutics Inc | Trans-clomiphene for metabolic syndrome |
| US20150031656A1 (en) | 2012-02-29 | 2015-01-29 | Repros Therapeutics Inc. | Combination therapy for treating androgen deficiency |
| HUE039052T2 (hu) | 2013-02-19 | 2018-12-28 | Novartis Ag | Benzotiofénszármazékok és azok készítményei szelektív ösztrogén receptor lebontóként |
| GB201311888D0 (en) * | 2013-07-03 | 2013-08-14 | Glaxosmithkline Ip Dev Ltd | Novel compounds |
| EP3373967B9 (en) | 2015-11-10 | 2023-10-04 | Paracrine Therapeutics AB | Treatment of er-negative breast cancer with an pdgf-cc inhibitor and an anti estrogen |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR003930A1 (es) * | 1995-02-28 | 1998-09-30 | Lilly Co Eli | Procedimiento para preparar compuestos de 2-fenil-3-fenoxi o feniltio-benzotiofeno y sales farmaceuticamente aceptables, compuestos intermediarios de aplicación exclusiva en dicho procedimiento y metodo para preparar los compuestos intermediarios mencionados |
| US5510357A (en) * | 1995-02-28 | 1996-04-23 | Eli Lilly And Company | Benzothiophene compounds as anti-estrogenic agents |
| US5731342A (en) * | 1996-02-22 | 1998-03-24 | Eli Lilly And Company | Benzothiophenes, formulations containing same, and methods |
-
1998
- 1998-04-02 ZA ZA9802818A patent/ZA982818B/xx unknown
- 1998-04-07 CA CA002286207A patent/CA2286207A1/en not_active Abandoned
- 1998-04-07 EA EA199900910A patent/EA199900910A1/ru unknown
- 1998-04-07 CN CN98805957A patent/CN1259945A/zh active Pending
- 1998-04-07 IL IL13227998A patent/IL132279A0/xx unknown
- 1998-04-07 PL PL98336206A patent/PL336206A1/xx unknown
- 1998-04-07 TR TR1999/03244T patent/TR199903244T2/xx unknown
- 1998-04-07 EP EP98915368A patent/EP0975628A4/en not_active Withdrawn
- 1998-04-07 KR KR1019997009295A patent/KR20010006215A/ko not_active Withdrawn
- 1998-04-07 HU HU0001845A patent/HUP0001845A2/hu unknown
- 1998-04-07 ID IDW991189A patent/ID23653A/id unknown
- 1998-04-07 AU AU69573/98A patent/AU6957398A/en not_active Abandoned
- 1998-04-07 WO PCT/US1998/006989 patent/WO1998045286A1/en not_active Ceased
- 1998-04-07 JP JP54309098A patent/JP2001518897A/ja active Pending
-
1999
- 1999-10-08 NO NO994902A patent/NO994902L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| ID23653A (id) | 2000-05-11 |
| EA199900910A1 (ru) | 2000-04-24 |
| AU6957398A (en) | 1998-10-30 |
| EP0975628A4 (en) | 2001-03-21 |
| KR20010006215A (ko) | 2001-01-26 |
| IL132279A0 (en) | 2001-03-19 |
| JP2001518897A (ja) | 2001-10-16 |
| NO994902D0 (no) | 1999-10-08 |
| TR199903244T2 (xx) | 2000-05-22 |
| HUP0001845A2 (hu) | 2001-06-28 |
| PL336206A1 (en) | 2000-06-05 |
| ZA982818B (en) | 1999-10-04 |
| WO1998045286A1 (en) | 1998-10-15 |
| CA2286207A1 (en) | 1998-10-15 |
| CN1259945A (zh) | 2000-07-12 |
| EP0975628A1 (en) | 2000-02-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |