NO995257L - Fremgangsmåte og materialer for diagnose og behandling av Reward Deficiency Syndrome - Google Patents

Fremgangsmåte og materialer for diagnose og behandling av Reward Deficiency Syndrome

Info

Publication number
NO995257L
NO995257L NO995257A NO995257A NO995257L NO 995257 L NO995257 L NO 995257L NO 995257 A NO995257 A NO 995257A NO 995257 A NO995257 A NO 995257A NO 995257 L NO995257 L NO 995257L
Authority
NO
Norway
Prior art keywords
inhibitor
precursor
phenylalanine
dopamine
enkephalinase
Prior art date
Application number
NO995257A
Other languages
English (en)
Other versions
NO995257D0 (no
Inventor
Kenneth Blum
David E Comings
John L Ivy
Original Assignee
Kenneth Blum Inc
Univ Texas
Hope Nat Medical Center
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kenneth Blum Inc, Univ Texas, Hope Nat Medical Center filed Critical Kenneth Blum Inc
Publication of NO995257D0 publication Critical patent/NO995257D0/no
Publication of NO995257L publication Critical patent/NO995257L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465—Nicotine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pathology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)

Abstract

Det beskrives forbedring av konsentrasjonsprosessering ved administrering av endorfinaseinhibitor eller enke- falinaseinhibitor, og valgfritt en dopaminforløper, eller en serotoninforløper, en GABA-forløper, eller en endorfin- eller enkefalinase-frigjører, eller visse urteforbindelser inkluderende Rhodediola rosea ekstrakt (Pharmaline) og/ eller Huperzine. Disse forbindelser fremmer gjenvinning av normal neurotransmitterfunksjon, og hvor materialene kombinert fremmer frigivelse av dopamin ved nucleus accumbens og er ikke vanedannende. Anvendelse av dopamin- forløpere L-phenylalanin, eller L-tyrosin, enkefalinase- inhibitoren D-fenylalanin, og/eller serotonin-forløper hydroksytryptofan og en naturlig acetylcholenesterase- inhibitor og kromsalter (dvs. picolinat, nicotinat, etc.) er spesielt foretrukket, men ikke begrenset, til å assistere i å frigi symptomer assosiert med fenylalanin- mangel i hjerne.
NO995257A 1997-04-29 1999-10-28 Fremgangsmåte og materialer for diagnose og behandling av Reward Deficiency Syndrome NO995257L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4439497P 1997-04-29 1997-04-29
PCT/US1998/008684 WO1998048785A2 (en) 1997-04-29 1998-04-29 Allelic polygene diagnosis of reward deficiency syndrome and treatment

Publications (2)

Publication Number Publication Date
NO995257D0 NO995257D0 (no) 1999-10-28
NO995257L true NO995257L (no) 1999-12-27

Family

ID=21932148

Family Applications (1)

Application Number Title Priority Date Filing Date
NO995257A NO995257L (no) 1997-04-29 1999-10-28 Fremgangsmåte og materialer for diagnose og behandling av Reward Deficiency Syndrome

Country Status (10)

Country Link
EP (1) EP0979092A2 (no)
JP (1) JP2002511850A (no)
KR (1) KR20010020422A (no)
CN (1) CN1261801A (no)
AU (1) AU7267798A (no)
CA (1) CA2288990A1 (no)
IL (1) IL132634A0 (no)
IS (1) IS5233A (no)
NO (1) NO995257L (no)
WO (1) WO1998048785A2 (no)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6622036B1 (en) * 2000-02-09 2003-09-16 Cns Response Method for classifying and treating physiologic brain imbalances using quantitative EEG
US6132724A (en) * 1998-04-29 2000-10-17 City Of Hope National Medical Center Allelic polygene diagnosis of reward deficiency syndrome and treatment
US6955873B1 (en) * 2000-08-04 2005-10-18 Kenneth Blum Diagnosis and treatment system for reward deficiency syndrome (RDS) and related behaviors
GB9927806D0 (en) * 1999-11-24 2000-01-26 Isis Innovation Genetic indicators of tobacco consumption
PT1347778E (pt) * 2000-12-01 2006-08-31 Be Able Llc Quimioterapia do comportamento.
ITRM20010218A1 (it) * 2001-04-23 2002-10-23 Sigma Tau Healthscience Spa Composizione per la prevenzione o il trattamento dei disturbi dell'apprendimento in bambini affetti da deficit dell'attenzione ed iperattivi
US8142799B2 (en) * 2001-12-18 2012-03-27 Tamea Rae Sisco High potency clinical anti-craving treatment and method of use
US8142800B1 (en) * 2001-12-18 2012-03-27 Tamea Rae Sisco Oral high potency clinical anti-craving treatment and method of use
US7713695B2 (en) * 2005-02-07 2010-05-11 Genenews, Inc. Mild osteoarthritis biomarkers and uses thereof
CN101523307B (zh) 2006-09-28 2011-06-15 三菱电机株式会社 故障检测装置以及故障检测方法
US20090318520A1 (en) * 2008-06-20 2009-12-24 Afecta Pharmaceuticals Drive Use of isoindoles for the treatment of neurobehavioral disorders
EP2485747A4 (en) * 2008-06-21 2013-10-23 Kenneth Blum CUSTOMIZATION DIRECTED BY THE DNA OF ANALGESIC COMPOUNDS AS A THERAPEUTIC MODALITY
WO2010005303A2 (en) * 2008-07-07 2010-01-14 Publiekrechtelijke Rechtspersoon Academisch Ziekenhuis Leiden H.O.D.N. Leids Universitair Medisch Centrum New indicators of human longevity and biological ageing rate
EP2552536B1 (en) 2010-04-01 2016-06-08 Ecole Polytechnique Fédérale de Lausanne (EPFL) Device for interacting with neurological tissue
WO2011133949A2 (en) * 2010-04-22 2011-10-27 Kenber, Llc Genetic risk analysis in reward deficiency syndrome
US9727691B2 (en) 2011-09-30 2017-08-08 Tokyo Metropolitan Institute Of Medical Science Method for evaluating drug sensitivity and disease vulnerability by analyzing cyclic AMP responsive element binding protein gene
JP2015067581A (ja) * 2013-09-30 2015-04-13 国立大学法人京都大学 多重共鳴用のプローブ
US11311718B2 (en) 2014-05-16 2022-04-26 Aleva Neurotherapeutics Sa Device for interacting with neurological tissue and methods of making and using the same
CN103990106A (zh) * 2014-06-11 2014-08-20 河北医科大学 八肽胆囊收缩素在制药中的应用
US9474894B2 (en) 2014-08-27 2016-10-25 Aleva Neurotherapeutics Deep brain stimulation lead
CN104846015B (zh) * 2015-05-27 2018-03-27 深圳先进技术研究院 特异性兴奋伏隔核中的gaba能神经元的组合物及其在改善精神分裂症异样行为中的应用
WO2017134587A1 (en) * 2016-02-02 2017-08-10 Aleva Neurotherapeutics, Sa Treatment of autoimmune diseases with deep brain stimulation
US11464756B1 (en) 2017-05-19 2022-10-11 Jerry Darm Mecuna pruriens, L-DOPA and 5-HTP based dietary supplements, pharmaceutical formulations and uses thereof
US10702692B2 (en) 2018-03-02 2020-07-07 Aleva Neurotherapeutics Neurostimulation device
DE102018114364B4 (de) * 2018-06-15 2026-04-23 Susanne Koch Vorrichtungen zur Bereitstellung eines Parameters, der auf eine erhöhte Wahrscheinlichkeit des Auftretens eines postoperativen Delirs hinweist
CN109316196B (zh) * 2018-12-12 2022-07-19 上海市精神卫生中心（上海市心理咨询培训中心） 基于虚拟现实联合脑电监测的苯丙胺类兴奋剂渴求评估方法
CN110507294B (zh) * 2019-08-07 2022-02-08 北京安龙脉德医学科技有限公司 基于互联网信息传递的急救系统
CN110991044B (zh) * 2019-12-03 2023-02-24 北京机电工程研究所 基于Agent建模的飞行器系统任务可靠性评估方法
CN112862751B (zh) * 2020-12-30 2022-05-31 电子科技大学 一种用于自闭症的自动诊断装置
CN113332299A (zh) * 2021-05-27 2021-09-03 广东湛江海洋医药研究院 红景天苷在缓解糖皮质激素性骨质疏松症中的应用
KR102434668B1 (ko) * 2022-03-02 2022-08-22 주식회사 국개대표 분리 불안 증상을 개선할 수 있는 반려동물용 사료 및 그 제조방법
CN115830001B (zh) * 2022-12-22 2023-09-08 抖音视界有限公司 肠道图像处理方法、装置、存储介质及电子设备
CN116310717B (zh) * 2023-02-14 2025-06-20 长沙理工大学 目标学生网络模型训练方法及低分辨率图像识别方法
CN116820166B (zh) * 2023-06-08 2024-07-19 武汉汉联智控科技有限公司 一种高低温控温控流量系统及方法

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Also Published As

Publication number Publication date
WO1998048785A3 (en) 1999-04-01
WO1998048785A9 (en) 1999-05-20
NO995257D0 (no) 1999-10-28
WO1998048785A2 (en) 1998-11-05
KR20010020422A (ko) 2001-03-15
CA2288990A1 (en) 1998-11-05
IL132634A0 (en) 2001-03-19
JP2002511850A (ja) 2002-04-16
IS5233A (is) 1999-10-28
CN1261801A (zh) 2000-08-02
EP0979092A2 (en) 2000-02-16
AU7267798A (en) 1998-11-24

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