NO996228L - Polynucleotid som koder et polypeptid med heparanaseaktivitet, og ekspresjon av samme i transduserte celler - Google Patents

Polynucleotid som koder et polypeptid med heparanaseaktivitet, og ekspresjon av samme i transduserte celler

Info

Publication number
NO996228L
NO996228L NO996228A NO996228A NO996228L NO 996228 L NO996228 L NO 996228L NO 996228 A NO996228 A NO 996228A NO 996228 A NO996228 A NO 996228A NO 996228 L NO996228 L NO 996228L
Authority
NO
Norway
Prior art keywords
polypeptide
same
expression
transduced cells
heparanase activity
Prior art date
Application number
NO996228A
Other languages
English (en)
Other versions
NO996228D0 (no
Inventor
Iris Pecker
Israel Vlodavsky
Elena Feinstein
Original Assignee
Insight Strategy & Marketing
Hadasit Med Res Service
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/922,170 external-priority patent/US5968822A/en
Application filed by Insight Strategy & Marketing, Hadasit Med Res Service filed Critical Insight Strategy & Marketing
Publication of NO996228D0 publication Critical patent/NO996228D0/no
Publication of NO996228L publication Critical patent/NO996228L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01166—Heparanase (3.2.1.166)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

Polynukleotid (hpa) som koder et polypeptid med heparanaseaktivitet, vektorer som inkluderer samme, transduserte celler som uttrykker heparanase samt et rekombinant protein med heparanaseaktivitet.
NO996228A 1997-09-02 1999-12-15 Polynucleotid som koder et polypeptid med heparanaseaktivitet, og ekspresjon av samme i transduserte celler NO996228L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/922,170 US5968822A (en) 1997-09-02 1997-09-02 Polynucleotide encoding a polypeptide having heparanase activity and expression of same in transduced cells
US10938698A 1998-07-02 1998-07-02
PCT/US1998/017954 WO1999011798A1 (en) 1997-09-02 1998-08-31 Polynucleotide encoding a polypeptide having heparanase activity and expression of same in transduced cells

Publications (2)

Publication Number Publication Date
NO996228D0 NO996228D0 (no) 1999-12-15
NO996228L true NO996228L (no) 2000-02-28

Family

ID=26806921

Family Applications (1)

Application Number Title Priority Date Filing Date
NO996228A NO996228L (no) 1997-09-02 1999-12-15 Polynucleotid som koder et polypeptid med heparanaseaktivitet, og ekspresjon av samme i transduserte celler

Country Status (3)

Country Link
KR (1) KR100549408B1 (no)
IL (3) IL133264A0 (no)
NO (1) NO996228L (no)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2878600A (en) 1999-03-01 2000-09-21 Hadasit Medical Research Services & Development Company Ltd Polynucleotide encoding a polypeptide having heparanase activity and expression of same in genetically modified cells

Also Published As

Publication number Publication date
IL133264A (en) 2006-12-31
KR20010023593A (ko) 2001-03-26
NO996228D0 (no) 1999-12-15
KR100549408B1 (ko) 2006-02-08
IL176290A0 (en) 2006-10-05
IL133264A0 (en) 2001-04-30

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