NO996395L - Alkyl-4-silylheterosykliske fenoler og tiofenoler som er anvendbare som antioksiderende midler - Google Patents

Alkyl-4-silylheterosykliske fenoler og tiofenoler som er anvendbare som antioksiderende midler

Info

Publication number
NO996395L
NO996395L NO996395A NO996395A NO996395L NO 996395 L NO996395 L NO 996395L NO 996395 A NO996395 A NO 996395A NO 996395 A NO996395 A NO 996395A NO 996395 L NO996395 L NO 996395L
Authority
NO
Norway
Prior art keywords
silylheterocyclic
phenols
antioxidants
alkyl
thiophenols
Prior art date
Application number
NO996395A
Other languages
English (en)
Norwegian (no)
Other versions
NO996395D0 (no
Inventor
Roger A Parker
Michael Louis Edwards
Paul S Wright
Steven J Busch
Kim S Chen
Mark Joseph Vaal
Jr James Edward Matt
Mark Thirston Yates
Original Assignee
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc
Publication of NO996395D0 publication Critical patent/NO996395D0/no
Publication of NO996395L publication Critical patent/NO996395L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/0803—Compounds with Si-C or Si-Si linkages
    • C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring
    • C07F7/0814—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring said ring is substituted at a C ring atom by Si
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Toxicology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Transplantation (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO996395A 1997-06-24 1999-12-22 Alkyl-4-silylheterosykliske fenoler og tiofenoler som er anvendbare som antioksiderende midler NO996395L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US88162797A 1997-06-24 1997-06-24
PCT/US1998/010510 WO1998058938A1 (en) 1997-06-24 1998-05-21 Alkyl-4-silylheterocyclic phenols and thiophenols as antioxidant agents

Publications (2)

Publication Number Publication Date
NO996395D0 NO996395D0 (no) 1999-12-22
NO996395L true NO996395L (no) 2000-02-23

Family

ID=25378856

Family Applications (1)

Application Number Title Priority Date Filing Date
NO996395A NO996395L (no) 1997-06-24 1999-12-22 Alkyl-4-silylheterosykliske fenoler og tiofenoler som er anvendbare som antioksiderende midler

Country Status (21)

Country Link
EP (1) EP0998477B1 (de)
JP (1) JP2002514226A (de)
KR (1) KR20010014118A (de)
CN (1) CN1147495C (de)
AR (1) AR013114A1 (de)
AT (1) ATE235498T1 (de)
AU (1) AU731278B2 (de)
BR (1) BR9810311A (de)
CA (1) CA2293461C (de)
DE (1) DE69812635T2 (de)
DK (1) DK0998477T3 (de)
ES (1) ES2190592T3 (de)
HU (1) HUP0002775A3 (de)
IL (1) IL133598A (de)
NO (1) NO996395L (de)
NZ (1) NZ501342A (de)
PT (1) PT998477E (de)
SI (1) SI0998477T1 (de)
TW (1) TW517054B (de)
WO (1) WO1998058938A1 (de)
ZA (1) ZA985318B (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005039596A1 (en) * 2003-10-17 2005-05-06 Amylin Pharmaceuticals, Inc. Silyl phenols for promoting vascular health

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5155250A (en) * 1990-07-05 1992-10-13 Merrell Dow Pharmaceuticals Inc. 2,6-di-alkyl-4-silyl-phenols as antiatheroscerotic agents
DE69434198T2 (de) * 1993-12-10 2005-12-29 Merrell Pharmaceuticals Inc., Cincinnati Verfahren zur senkung des serumcholesterinspiegels mit 2,6-dialkyl-4 silyl-phenol derivaten

Also Published As

Publication number Publication date
DE69812635T2 (de) 2003-10-23
ATE235498T1 (de) 2003-04-15
AU7591598A (en) 1999-01-04
CA2293461A1 (en) 1998-12-30
WO1998058938A1 (en) 1998-12-30
DE69812635D1 (de) 2003-04-30
IL133598A (en) 2004-08-31
HUP0002775A3 (en) 2001-08-28
DK0998477T3 (da) 2003-07-21
ZA985318B (en) 1999-01-11
IL133598A0 (en) 2001-04-30
CN1261367A (zh) 2000-07-26
NZ501342A (en) 2001-10-26
TW517054B (en) 2003-01-11
CN1147495C (zh) 2004-04-28
HK1027815A1 (en) 2001-01-23
JP2002514226A (ja) 2002-05-14
AR013114A1 (es) 2000-12-13
BR9810311A (pt) 2000-09-19
CA2293461C (en) 2004-02-24
PT998477E (pt) 2003-07-31
ES2190592T3 (es) 2003-08-01
KR20010014118A (ko) 2001-02-26
NO996395D0 (no) 1999-12-22
EP0998477A1 (de) 2000-05-10
EP0998477B1 (de) 2003-03-26
SI0998477T1 (en) 2003-08-31
AU731278B2 (en) 2001-03-29
HUP0002775A2 (hu) 2001-05-28

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Legal Events

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FC2A Withdrawal, rejection or dismissal of laid open patent application