NZ501831A - Trail binding protein (TRAIL-BP) showing significant homology to the extracellular domains of members of the tumour necrosis factor receptor (TNF-R) and is anchored to cell surface via glycosylphosphatidylinositol (GPI) linkage - Google Patents

Trail binding protein (TRAIL-BP) showing significant homology to the extracellular domains of members of the tumour necrosis factor receptor (TNF-R) and is anchored to cell surface via glycosylphosphatidylinositol (GPI) linkage

Info

Publication number
NZ501831A
NZ501831A NZ501831A NZ50183198A NZ501831A NZ 501831 A NZ501831 A NZ 501831A NZ 501831 A NZ501831 A NZ 501831A NZ 50183198 A NZ50183198 A NZ 50183198A NZ 501831 A NZ501831 A NZ 501831A
Authority
NZ
New Zealand
Prior art keywords
trail
polypeptide
seq
dna
binding
Prior art date
Application number
NZ501831A
Other languages
English (en)
Inventor
Henning Walczak
Craig A Smith
Original Assignee
Immunex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immunex Corp filed Critical Immunex Corp
Publication of NZ501831A publication Critical patent/NZ501831A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70578NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NZ501831A 1997-06-26 1998-06-25 Trail binding protein (TRAIL-BP) showing significant homology to the extracellular domains of members of the tumour necrosis factor receptor (TNF-R) and is anchored to cell surface via glycosylphosphatidylinositol (GPI) linkage NZ501831A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US88352997A 1997-06-26 1997-06-26
PCT/US1998/013491 WO1999000423A1 (fr) 1997-06-26 1998-06-25 Proteine se fixant a la proteine trail

Publications (1)

Publication Number Publication Date
NZ501831A true NZ501831A (en) 2001-09-28

Family

ID=25382755

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ501831A NZ501831A (en) 1997-06-26 1998-06-25 Trail binding protein (TRAIL-BP) showing significant homology to the extracellular domains of members of the tumour necrosis factor receptor (TNF-R) and is anchored to cell surface via glycosylphosphatidylinositol (GPI) linkage

Country Status (7)

Country Link
EP (1) EP1001990A4 (fr)
JP (1) JP2002507127A (fr)
AU (1) AU756759B2 (fr)
CA (1) CA2294704A1 (fr)
IL (1) IL133602A0 (fr)
NZ (1) NZ501831A (fr)
WO (1) WO1999000423A1 (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6455040B1 (en) 1997-01-14 2002-09-24 Human Genome Sciences, Inc. Tumor necrosis factor receptor 5
US6261801B1 (en) 1997-01-14 2001-07-17 Human Genome Sceineces, Inc. Nucleic acids encoding tumor necrosis factor receptor 5
US6313269B1 (en) 1997-03-14 2001-11-06 Smithkline Beecham Corporation Tumor necrosis factor related receptor, TR6
US6872568B1 (en) 1997-03-17 2005-03-29 Human Genome Sciences, Inc. Death domain containing receptor 5 antibodies
CN1624128A (zh) 1997-03-17 2005-06-08 人类基因组科学公司 包含死亡结构域的受体-5
WO2000071150A1 (fr) * 1999-05-20 2000-11-30 Human Genome Sciences, Inc. Recepteur 5 du facteur de necrose tumorale
KR100436089B1 (ko) * 2000-07-06 2004-06-14 설대우 분비성 재조합 트라이머형의 트레일 단백질 생산을 위한 디엔에이 카세트, 테트라사이클린/독시사이클린-유도성아데노-관련 바이러스 벡터, 이 둘의 조합, 및 이들을이용한 유전자 치료
MXPA03010747A (es) 2001-05-25 2004-03-02 Human Genome Sciences Inc Anticuerpos que se unen inmunoespecificamente a receptores de ligando inductor de apoptosis relacionado con factor de necrosis tumoral.
US7361341B2 (en) 2001-05-25 2008-04-22 Human Genome Sciences, Inc. Methods of treating cancer using antibodies that immunospecifically bind to trail receptors
US7348003B2 (en) 2001-05-25 2008-03-25 Human Genome Sciences, Inc. Methods of treating cancer using antibodies that immunospecifically bind to TRAIL receptors
KR20050035511A (ko) * 2001-10-13 2005-04-18 아스테리온 리미티드 폴리펩타이드들을 포함하는 글리코실포스파티딜이노시톨
RU2340628C2 (ru) * 2001-10-13 2008-12-10 Астерион Лимитед Слитый белок, ингибирующий рецепторную передачу сигнала гормона роста (варианты), способ его получения и очистки и фармацевтическая композиция на его основе
RU2433185C2 (ru) 2004-03-11 2011-11-10 Дженентек, Инк. Способ получения полипептидов
US11299528B2 (en) 2014-03-11 2022-04-12 D&D Pharmatech Inc. Long acting TRAIL receptor agonists for treatment of autoimmune diseases
WO2017106627A1 (fr) 2015-12-17 2017-06-22 The Johns Hopkins University Amélioration de la sclérose systémique à l'aide d'agonistes de récepteurs de mort cellulaire
KR102508650B1 (ko) 2016-04-07 2023-03-13 더 존스 홉킨스 유니버시티 사멸 수용체 작용제로써 췌장암 및 통증을 치료하기 위한 조성물 및 방법

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6261801B1 (en) * 1997-01-14 2001-07-17 Human Genome Sceineces, Inc. Nucleic acids encoding tumor necrosis factor receptor 5
CA2221687A1 (fr) * 1997-02-05 1998-08-05 Smithkline Beecham Corporation Recepteurs relies a la necrose des tumeurs, tr5
EP2083079A1 (fr) * 1997-06-18 2009-07-29 Genentech, Inc. Apo-2DcR

Also Published As

Publication number Publication date
CA2294704A1 (fr) 1999-01-07
AU8175898A (en) 1999-01-19
WO1999000423A1 (fr) 1999-01-07
EP1001990A1 (fr) 2000-05-24
JP2002507127A (ja) 2002-03-05
IL133602A0 (en) 2001-04-30
AU756759B2 (en) 2003-01-23
EP1001990A4 (fr) 2001-12-19

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