OA03786A - Procédé pour la préparation de dérivés du benzo-cyclohepta-thiophène. - Google Patents

Procédé pour la préparation de dérivés du benzo-cyclohepta-thiophène.

Info

Publication number: OA03786A
Authority: OA; OAPI
Prior art keywords: cyclohepta; benzo; preparation; thiophene derivatives; thiophene
Prior art date: 1970-03-11

Application number

OA54351A

Other languages

English (en)

Original Assignee

Sandoz Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1970-03-11

Filing date

1971-09-03

Publication date

1971-12-24

1970-03-11 Priority claimed from CH359870A external-priority patent/CH533639A/de

1970-09-24 Priority claimed from CH1412070A external-priority patent/CH537404A/de

1971-09-03 Application filed by Sandoz Sa filed Critical Sandoz Sa

1971-12-24 Publication of OA03786A publication Critical patent/OA03786A/fr

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/78—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
- C07D333/80—Seven-membered rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

OA54351A 1970-03-11 1971-09-03 Procédé pour la préparation de dérivés du benzo-cyclohepta-thiophène. OA03786A (fr)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
CH359870A CH533639A (de)	1970-03-11	1970-03-11	Verfahren zur Herstellung neuer Benzo(4,5)cyclohepta(1,2-b)-thiophen-Derivate
CH1159370A CH531000A (de)	1970-03-11	1970-07-31	Verfahren zur Herstellung neuer Benzocycloheptathiophene
CH1412070A CH537404A (de)	1970-09-24	1970-09-24	Verfahren zur Herstellung neuer Thiophenderivate
CH163271		1971-02-04

Publications (1)

Publication Number	Publication Date
OA03786A true OA03786A (fr)	1971-12-24

Family

ID=27428249

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
OA54190A OA03692A (fr)	1970-03-11	1971-03-09	Nouveaux dérivés du benzo-cyclohepta-thiopène et leur préparation.
OA54351A OA03786A (fr)	1970-03-11	1971-09-03	Procédé pour la préparation de dérivés du benzo-cyclohepta-thiophène.

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
OA54190A OA03692A (fr)	1970-03-11	1971-03-09	Nouveaux dérivés du benzo-cyclohepta-thiopène et leur préparation.

Country Status (12)

Country	Link
US (4)	US3682930A (fr)
AT (2)	AT319238B (fr)
BE (2)	BE764019A (fr)
CA (2)	CA960673A (fr)
CH (1)	CH531000A (fr)
DE (2)	DE2111071C3 (fr)
FR (2)	FR2085695B1 (fr)
GB (4)	GB1355539A (fr)
LU (2)	LU62757A1 (fr)
NL (2)	NL167431C (fr)
OA (2)	OA03692A (fr)
SE (2)	SE368954B (fr)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH531000A (de) *	1970-03-11	1972-11-30	Sandoz Ag	Verfahren zur Herstellung neuer Benzocycloheptathiophene
BE794377A (fr) *	1972-01-24	1973-07-23	Sandoz Sa	Nouveaux derives du benzo-cyclohepta-thiophene
US3960894A (en) *	1972-01-24	1976-06-01	Sandoz Ltd.	9-Bromo-or chloro-9,10-dihydro-10-dihydro-10-alkoxy-4H-benzo[4,5]cyclo-hepta[1,2-b]thiophen-4-ones
US4072756A (en) *	1973-05-17	1978-02-07	Sandoz Ltd.	Tricyclo piperidino ketones and soporific compositions thereof
CA1041100A (fr) *	1973-10-04	1978-10-24	Herbert G. Johnson	Acide pyridine-diyldioxamique
CH580621A5 (fr) *	1973-10-08	1976-10-15	Sandoz Ag
US4073915A (en) *	1975-05-20	1978-02-14	Sandoz Ltd.	Treating asthma
FI761607A7 (fr) *	1975-06-16	1976-12-17	Sandoz Ag
US4128549A (en) *	1976-02-27	1978-12-05	Sandoz Ltd.	Precursors of 4-(1-alkyl-4-piperidylidene-4H-benzo[4,5]cyclohepta-[1,2-b]thiophen-10(9H)-ones
US4282233B1 (en) *	1980-06-19	2000-09-05	Schering Corp	Antihistaminic 11-(4-piperidylidene)-5h-benzoÄ5,6Ü-cyclohepta-Ä1,2Ü-pyridines
DE3045135A1 (de) *	1980-11-29	1982-06-09	Sandoz-Patent-GmbH, 7850 Lörrach	Pharmazeutische kompositionen enthaltende bioabbaubare polymere
NL8701335A (nl) *	1986-06-21	1988-01-18	Sandoz Ag	Orale farmaceutische preparaten.
US5089496A (en) *	1986-10-31	1992-02-18	Schering Corporation	Benzo[5,6]cycloheptapyridine compounds, compositions and method of treating allergies
US5438062A (en) *	1986-10-31	1995-08-01	Schering Corporation	Benzo(5,6)cycloheptapyridines, compositions and methods of use
DZ1460A1 (fr) *	1989-11-22	2004-09-13	Sod Conseils Rech Applic	Nouveaux dérivés du sélénophèn ainsi que leur procédé de préparation.
CA2038417A1 (fr) *	1990-04-11	1991-10-12	Yasuo Ito	Composes de piperidine, methode de preparation de ces composes, et une composition pharmaceutique qui en contient.
EP0552292B1 (fr) *	1990-10-10	1995-06-21	Schering Corporation	Imidazobenzazepines substituees et imidazopyridazepines
US5891460A (en) *	1995-06-07	1999-04-06	University Of Southern California University Park Campus	Method for reducing or preventing post-surgical adhesion formation using ketotifen and analogs thereof
US6207684B1 (en)	1997-06-09	2001-03-27	Bridge Pharma, Inc.	Compounds with combined antihistaminic and mast cell stabilizing activities, intended for ophthalmic use
US6221897B1 (en) *	1998-06-10	2001-04-24	Aventis Pharma Deutschland Gmbh	Benzothiepine 1,1-dioxide derivatives, a process for their preparation, pharmaceuticals comprising these compounds, and their use
PL353586A1 (en)	1999-09-13	2003-12-01	Bridge Pharma, Inc.Bridge Pharma, Inc.	Optically active isomers of ketotifen and therapeutically active metabolites thereof
AU5139800A (en) *	1999-12-01	2001-06-12	Klein Pharmaceuticals	Topical administration of ketotifen
US20030212078A1 (en) *	2001-05-17	2003-11-13	Klein Gerald L.	Topical administration of pharmacological compositions for non-systemic treatment of pruritus
PT1583542E (pt)	2003-01-14	2008-09-17	Gilead Sciences Inc	Composições e métodos para terapia de combinação antiviral
CN100381439C (zh) *	2005-04-05	2008-04-16	浙江华海药业股份有限公司	9,10-二溴-9,10-二氢-4-H苯并[4,5]环庚烯并[1,2-b]噻吩-4-酮的制备方法
TWI375560B (en) *	2005-06-13	2012-11-01	Gilead Sciences Inc	Composition comprising dry granulated emtricitabine and tenofovir df and method for making the same
TWI471145B (zh)	2005-06-13	2015-02-01	Bristol Myers Squibb & Gilead Sciences Llc	單一式藥學劑量型
WO2008153761A1 (fr) *	2007-05-23	2008-12-18	Mastcell Pharmaceuticals, Inc.	Méthodes
TWI429641B (zh)	2008-01-30	2014-03-11	Nippon Zoki Pharmaceutical Co	哌啶衍生物
WO2009142772A2 (fr)	2008-05-23	2009-11-26	Mastcell Pharmaceuticals, Inc.	Méthodes et traitement d’allergies et inflammations associées à des pathologies gastro-intestinales
ES2561227T3 (es) *	2008-08-01	2016-02-25	Nippon Zoki Pharmaceutical Co., Ltd.	Derivado de aminopropilideno
CN102471326B (zh) *	2009-07-28	2015-04-29	日本脏器制药株式会社	硫杂苯并薁丙酸衍生物的制备方法
EA038594B1 (ru)	2011-10-28	2021-09-21	Шайр Хьюман Дженетик Терапис, Инк.	Ингибиторы рециркуляции желчных кислот для лечения гиперхолемии и холестатического заболевания печени
JP6217938B2 (ja)	2011-10-28	2017-10-25	ルメナファーマシューティカルズエルエルシー	小児の胆汁うっ滞性肝疾患の処置のための胆汁酸再循環阻害剤
US8778971B2 (en)	2012-10-23	2014-07-15	Bridge Pharma, Inc.	Medicinal treatment of dermal diseases in companion animals
US8557846B1 (en)	2012-10-23	2013-10-15	Bridge Pharma, Inc.	Medicinal treatment of dermal diseases in dogs
US20150272941A1 (en)	2012-10-30	2015-10-01	Bridge Pharma, Inc.	Medicinal treatment of chronic pulmonary inflammatory diseases with norketotifen
US20140120121A1 (en)	2012-10-30	2014-05-01	Bridge Pharma, Inc.	Medicinal treatment of atopic inflammatory diseases
US9439895B2 (en)	2013-08-06	2016-09-13	Bridge Pharma, Inc.	Methods of treating pruritic conditions mediated through non-histaminergic mechanisms in diabetic patients
US9138431B2 (en)	2013-08-06	2015-09-22	Bridge Pharma, Inc.	Methods of treatment of histamine H-4 receptor-related pruritus
US9345697B2 (en)	2013-08-06	2016-05-24	Bridge Pharma, Inc.	Methods of treatment of non-histaminic pruritus
EP3307270B1 (fr)	2015-06-11	2018-10-17	Bridge Pharma, Inc.	Procédé pour traiter le prurit non-histaminique chez les mammifères
MX2018011699A (es)	2018-09-26	2019-07-24	Federico Amezcua Amezcua	Composicion farmaceutica sinergica de un antagonista de los receptores de leucotrienos y un agonista inverso de la histamina h1.
US10959992B2 (en)	2019-02-22	2021-03-30	Bridge Pharma Inc.	Methods of treatment of asthma and COPD

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL297097A (fr) *	1962-08-31
FR1437412A (fr) *	1963-12-19	1966-05-06	Sandoz Sa	Nouveaux benzo-cyclohepta-thiophènes et leur préparation
US3491103A (en) *	1963-12-19	1970-01-20	Sandoz Ag	Certain 4h-benzo(4,5)cyclohepta-(1,2-b) thiophenes
GB1084448A (en) *	1963-12-20	1967-09-20	Sandoz Ltd	Improvements in or relating to 4h-benzo[4,5]cyclohepta[1,2-b]thiophen-4-one derivatives
CH537897A (de) *	1968-03-20	1973-06-15	Hoffmann La Roche	Verfahren zur Herstellung von tricyclischen Verbindungen
US3574199A (en) *	1968-06-28	1971-04-06	Searle & Co	6-(aminoalkyl- and aminoalkylidene)-1,1a,6,10b -tetrahydro-dibenzo(a,e)cyclopropa(c)cycloheptenes
CH531000A (de) *	1970-03-11	1972-11-30	Sandoz Ag	Verfahren zur Herstellung neuer Benzocycloheptathiophene
US3709947A (en) *	1971-07-26	1973-01-09	Searle & Co	6-chloropropylidene-1,1a,6,10b-tetrahydrobenzo(a,e)cyclopropa(c)cycloheptenes

1970
- 1970-07-31 CH CH1159370A patent/CH531000A/de not_active IP Right Cessation
1971
- 1971-03-03 US US120738A patent/US3682930A/en not_active Expired - Lifetime
- 1971-03-08 FR FR7107901A patent/FR2085695B1/fr not_active Expired
- 1971-03-09 OA OA54190A patent/OA03692A/fr unknown
- 1971-03-09 BE BE764019A patent/BE764019A/fr not_active IP Right Cessation
- 1971-03-09 DE DE2111071A patent/DE2111071C3/de not_active Expired
- 1971-03-09 LU LU62757D patent/LU62757A1/xx unknown
- 1971-03-10 NL NL7103174.A patent/NL167431C/xx not_active IP Right Cessation
- 1971-03-10 AT AT206471A patent/AT319238B/de not_active IP Right Cessation
- 1971-03-10 SE SE03074/71A patent/SE368954B/xx unknown
- 1971-03-10 CA CA107,340A patent/CA960673A/en not_active Expired
- 1971-04-19 GB GB2882373A patent/GB1355539A/en not_active Expired
- 1971-04-19 GB GB2348271*A patent/GB1355537A/en not_active Expired
- 1971-06-04 GB GB1894073A patent/GB1355538A/en not_active Expired
- 1971-08-27 NL NLAANVRAGE7111808,A patent/NL171449C/xx not_active IP Right Cessation
- 1971-08-30 BE BE771964A patent/BE771964A/fr unknown
- 1971-08-31 CA CA121,762A patent/CA947767A/en not_active Expired
- 1971-09-02 AT AT766471A patent/AT321905B/de not_active IP Right Cessation
- 1971-09-02 LU LU63829D patent/LU63829A1/xx unknown
- 1971-09-03 SE SE7111154A patent/SE378820B/xx unknown
- 1971-09-03 OA OA54351A patent/OA03786A/fr unknown
- 1971-09-03 FR FR7131866A patent/FR2107917B1/fr not_active Expired
- 1971-09-06 DE DE19712144490 patent/DE2144490A1/de active Pending
- 1971-09-07 US US00178449A patent/US3770728A/en not_active Expired - Lifetime
- 1971-09-21 GB GB4392471A patent/GB1360219A/en not_active Expired
1972
- 1972-08-07 US US00278244A patent/US3749786A/en not_active Expired - Lifetime
- 1972-08-08 US US00278738A patent/US3853915A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
NL7111808A (fr)	1972-03-28
OA03692A (fr)	1971-12-24
LU62757A1 (fr)	1971-10-13
US3682930A (en)	1972-08-08
LU63829A1 (fr)	1972-06-27
FR2085695A1 (fr)	1971-12-31
SE368954B (fr)	1974-07-29
SE378820B (fr)	1975-09-15
GB1360219A (en)	1974-07-17
DE2111071A1 (de)	1971-09-23
AT319238B (de)	1974-12-10
US3853915A (en)	1974-12-10
FR2107917A1 (fr)	1972-05-12
DE2111071B2 (de)	1978-11-09
BE771964A (fr)	1972-02-29
FR2107917B1 (fr)	1975-04-18
DE2144490A1 (de)	1972-03-30
AT321905B (de)	1975-04-25
GB1355539A (en)	1974-06-05
NL7103174A (fr)	1971-09-14
US3770728A (en)	1973-11-06
GB1355537A (en)	1974-06-05
NL167431C (nl)	1981-12-16
FR2085695B1 (fr)	1974-11-15
NL171449C (nl)	1983-04-05
GB1355538A (en)	1974-06-05
BE764019A (fr)	1971-09-09
CA960673A (en)	1975-01-07
DE2111071C3 (de)	1979-07-12
CA947767A (en)	1974-05-21
CH531000A (de)	1972-11-30
US3749786A (en)	1973-07-31

Publication	Publication Date	Title
CH513174A (fr)	1971-09-30	Procédé pour la préparation de dérivés du quinuclidinol
OA03930A (fr)	1975-08-14	Procédé de préparation d'azapurinones.
CH539643A (fr)	1973-07-31	Procédé pour la préparation de dérivés de la benzazine
BE771964A (fr)	1972-02-29	Procede pour la preparation de derives du benzo-cyclohepta-thiophene
CH502378A (fr)	1971-01-31	Procédé pour la préparation de dérivés de la phénothiazine
CH544056A (fr)	1973-11-15	Procédé de préparation de dérivés du cyclopentane
OA04406A (fr)	1980-02-29	Procédé de préparation de dérivés de 14-hydroxy-morphinane.
CH500930A (fr)	1970-12-31	Procédé de préparation de dérivés du naphtacène
OA03731A (fr)	1971-12-24	Procédé de préparation de 7-halogénolincomycines.
FR1439925A (fr)	1966-05-27	Procédé pour la préparation de dérivés cyclopenténoniques
FR1428086A (fr)	1966-02-11	Procédé pour la préparation de dérivés de dibenzocycloheptatriène
CH509975A (fr)	1971-07-15	Procédé de préparation de dérivés de la phloramine
FR1470809A (fr)	1967-02-24	Procédé pour la préparation de dérivés de nu-acyl-vinylamines
CH532056A (fr)	1972-12-31	Procédé de préparation de dérivés de 4-amino-2-styrylquinazoline
OA03891A (fr)	1975-08-14	Procédé de préparation de dérivés de la dihydrotriazine.
CH542227A (fr)	1973-11-15	Procédé de préparation de dérivés du dibenzothiophène
CH533618A (fr)	1973-02-15	Procédé de préparation de dérivés de nitroso-1-pyrrolidine
CH533104A (fr)	1973-01-31	Procédé pour la préparation de 5-azaspiro-(2,4)-heptanes
CH537389A (fr)	1973-05-31	Procédé pour la préparation de dérivés de la phtalazine
OA03905A (fr)	1975-08-14	Procédé de préparation de nouveaux dérivés de la thiazolino-pyrimidone-5.
CH523878A (fr)	1972-06-15	Procédé de préparation de dérivés du benzofuranne
OA03484A (fr)	1971-03-30	Procédé de préparation de dérivés du pyrrole.
CH532590A (fr)	1973-01-15	Procédé de préparation de benzodiazépine-1,4-one-2
CH539631A (fr)	1973-07-31	Procédé pour la préparation de dérivés hétérocycliques
CH522601A (fr)	1972-06-30	Procédé pour la préparation de dérivés aminoacétyliques de la 2,3-diphényl-cyclopropylamine