OA06699A - Les éthers pharmaceutiques, leur préparation, leur utilisation et les produits intermédiaires pour ces éthers et leur préparation. - Google Patents

Les éthers pharmaceutiques, leur préparation, leur utilisation et les produits intermédiaires pour ces éthers et leur préparation.

Info

Publication number
OA06699A
OA06699A OA57193A OA57193A OA06699A OA 06699 A OA06699 A OA 06699A OA 57193 A OA57193 A OA 57193A OA 57193 A OA57193 A OA 57193A OA 06699 A OA06699 A OA 06699A
Authority
OA
OAPI
Prior art keywords
preparation
ethers
pharmaceutical
intermediates therefor
intermediates
Prior art date
Application number
OA57193A
Other languages
English (en)
Inventor
Kneen Geoffrey
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of OA06699A publication Critical patent/OA06699A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/125—Saturated compounds having only one carboxyl group and containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/30—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing —CHO groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/74—Unsaturated compounds containing —CHO groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
OA57193A 1979-06-29 1980-08-09 Les éthers pharmaceutiques, leur préparation, leur utilisation et les produits intermédiaires pour ces éthers et leur préparation. OA06699A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7922781 1979-06-29

Publications (1)

Publication Number Publication Date
OA06699A true OA06699A (fr) 1982-05-31

Family

ID=10506199

Family Applications (1)

Application Number Title Priority Date Filing Date
OA57193A OA06699A (fr) 1979-06-29 1980-08-09 Les éthers pharmaceutiques, leur préparation, leur utilisation et les produits intermédiaires pour ces éthers et leur préparation.

Country Status (18)

Country Link
US (1) US4410537A (fr)
EP (1) EP0022229B1 (fr)
JP (1) JPS5649335A (fr)
KR (2) KR850000073B1 (fr)
AU (1) AU545274B2 (fr)
DE (1) DE3061269D1 (fr)
DK (1) DK159770C (fr)
FI (1) FI71929C (fr)
GB (1) GB2053218B (fr)
GR (1) GR68748B (fr)
HU (1) HU190774B (fr)
IL (1) IL60422A (fr)
IT (1) IT1133025B (fr)
MW (1) MW2380A1 (fr)
OA (1) OA06699A (fr)
ZA (1) ZA803880B (fr)
ZM (1) ZM5780A1 (fr)
ZW (1) ZW14480A1 (fr)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2090830B (en) * 1980-12-18 1984-09-26 Wellcome Found Formyl ether derivatives
GB8606913D0 (en) * 1986-03-20 1986-04-23 Hider R C Treatment of sickle cell disease
US6083522A (en) 1997-01-09 2000-07-04 Neucoll, Inc. Devices for tissue repair and methods for preparation and use thereof
RU2300516C2 (ru) * 1999-11-05 2007-06-10 Эмисфере Текнолоджиз, Инк. Соединения феноксикарбоновой кислоты и композиции для доставки активных веществ
US7279597B1 (en) 1999-11-05 2007-10-09 Emisphere Technologies, Inc. Phenyl amine carboxylic acid compounds and compositions for delivering active agents
US7129274B1 (en) 1999-11-05 2006-10-31 Emisphere Technologies Inc. Phenoxy carboxylic acid compounds and compositions for delivering active agents
AU2622301A (en) * 1999-11-05 2001-05-14 Emisphere Technologies, Inc. Phenyl amine carboxylic acid compounds and compositions for delivering active agents
WO2001070663A2 (fr) * 2000-03-17 2001-09-27 Corixa Corporation Nouveaux aldehydes amphipathiques et leur utilisation en tant qu'adjuvants et effecteurs immunologiques
US8246969B2 (en) 2001-11-16 2012-08-21 Skinmedica, Inc. Compositions containing aromatic aldehydes and their use in treatments
CN103442702B (zh) 2011-01-07 2016-02-10 阿勒根公司 黑色素改良组合物及其使用方法
CA3142817A1 (fr) 2011-12-28 2013-07-04 Global Blood Therapeutics, Inc. Composes benzaldehyde substitues et procedes d'utilisation de ceux-ci dans l'augmentation de l'oxygenation des tissus
ES2790358T3 (es) * 2011-12-28 2020-10-27 Global Blood Therapeutics Inc Compuestos de heteroaril aldehído sustituido y métodos para su uso en el aumento de la oxigenación tisular
US9458139B2 (en) 2013-03-15 2016-10-04 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US9802900B2 (en) 2013-03-15 2017-10-31 Global Blood Therapeutics, Inc. Bicyclic heteroaryl compounds and uses thereof for the modulation of hemoglobin
US9422279B2 (en) 2013-03-15 2016-08-23 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US9604999B2 (en) 2013-03-15 2017-03-28 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US10100043B2 (en) 2013-03-15 2018-10-16 Global Blood Therapeutics, Inc. Substituted aldehyde compounds and methods for their use in increasing tissue oxygenation
EP3919056B1 (fr) 2013-03-15 2024-08-28 Global Blood Therapeutics, Inc. Composés et leurs utilisations pour la modulation de l'hémoglobine
EP2968299B1 (fr) 2013-03-15 2021-01-20 Global Blood Therapeutics, Inc. Composés et leurs utilisations pour la modulation de l'hémoglobine
US8952171B2 (en) 2013-03-15 2015-02-10 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US10266551B2 (en) 2013-03-15 2019-04-23 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US20140274961A1 (en) 2013-03-15 2014-09-18 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
CN112500338A (zh) 2013-03-15 2021-03-16 全球血液疗法股份有限公司 化合物及其用于调节血红蛋白的用途
EP3036222A2 (fr) * 2013-08-23 2016-06-29 Virginia Commonwealth University Dérivés de type nitrates d'ester d'aldéhydes aromatiques doués de multiples propriétés pharmacologiques pour traiter la drépanocytose
EA202092627A1 (ru) 2013-11-18 2021-09-30 Глобал Блад Терапьютикс, Инк. Соединения и их применения для модуляции гемоглобина
SG10201911662YA (en) 2014-02-07 2020-02-27 Global Blood Therapeutics Inc Crystalline polymorphs of the free base of 2-hydroxy-6-((2-(1-isopropyl-1h-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde
HK1249052A1 (zh) 2015-03-06 2018-10-26 BeyondSpring Pharmaceuticals Inc. 治疗与ras突变相关的癌症的方法
MA41841A (fr) 2015-03-30 2018-02-06 Global Blood Therapeutics Inc Composés aldéhyde pour le traitement de la fibrose pulmonaire, de l'hypoxie, et de maladies auto-immunes et des tissus conjonctifs
HUE072191T2 (hu) 2015-12-04 2025-10-28 Global Blood Therapeutics Inc A 2-hidoxi-6-((2-(1-izopropil-1H-pirazol-5-il)piridin-3-il)metoxi)benzaldehid adagolási rendje
SG11201806583XA (en) * 2016-02-08 2018-09-27 Beyondspring Pharmaceuticals Inc Compositions containing tucaresol or its analogs
TWI825524B (zh) 2016-05-12 2023-12-11 美商全球血液治療公司 用於合成2-羥基-6-((2-(1-異丙基-1h-吡唑-5-基)-吡啶-3-基)甲氧基)苯甲醛之方法
BR112018074990A2 (pt) 2016-06-06 2019-03-12 Beyondspring Pharmaceuticals, Inc. composição, usos e método para reduzir neutropenia
TWI778983B (zh) 2016-10-12 2022-10-01 美商全球血液治療公司 包含2-羥基-6-((2-(1-異丙基-1h-吡唑-5-基)吡啶-3-基)甲氧基)-苯甲醛之片劑
US11633393B2 (en) 2017-01-06 2023-04-25 Beyondspring Pharmaceuticals, Inc. Tubulin binding compounds and therapeutic use thereof
EP3576733A4 (fr) 2017-02-01 2020-11-25 Beyondspring Pharmaceuticals, Inc. Méthode de réduction de la neutropénie
WO2019182938A1 (fr) * 2018-03-22 2019-09-26 Virginia Commonwealth University Aldéhydes aromatiques ayant une activité pharmacologique soutenue et améliorée in vitro et in vivo pour traiter la drépanocytose
US11014884B2 (en) 2018-10-01 2021-05-25 Global Blood Therapeutics, Inc. Modulators of hemoglobin
CR20210335A (es) 2018-11-19 2021-09-14 Global Blood Therapeutics Inc Compuestos de 2-formil-3-hidroxifeniloximetilo capaces de modular la hemoglobina
US12479816B2 (en) 2019-02-08 2025-11-25 University of Pittsburgh—of the Commonwealth System of Higher Education 20-HETE formation inhibitors
EP4319751A4 (fr) 2021-04-09 2025-02-26 Beyondspring Pharmaceuticals, Inc. Compositions thérapeutiques et méthodes de traitement de tumeurs
AU2023376662B2 (en) * 2022-11-07 2025-06-05 Children's Hospital Of Philadelphia (Chop) Benzaldehyde compounds with direct polymer destabilizing effects to treat sickle cell disease

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL105100C (fr) * 1958-04-30
CH543472A (fr) * 1969-01-31 1973-10-31 Orchimed Sa Procédé pour la préparation d'acides phénoxyalcoyl-carboxyliques
DE2209128C3 (de) 1971-03-05 1981-10-22 CIBA-GEIGY AG, 4002 Basel Bis-Stilbenverbindungen, Verfahren zu deren Herstellung und deren Verwendung als optische Aufheller
CH550776A (de) 1971-03-05 1974-06-28 Ciba Geigy Ag Herstellung neuer bis-stilbenverbindungen.
GB1511645A (en) 1974-05-31 1978-05-24 Univ Ife Sickle cell anaemia treatment
US4137309A (en) * 1976-10-14 1979-01-30 The Procter & Gamble Company Therapeutic treatment

Also Published As

Publication number Publication date
IL60422A (en) 1984-06-29
US4410537A (en) 1983-10-18
EP0022229B1 (fr) 1982-12-08
EP0022229A1 (fr) 1981-01-14
GR68748B (fr) 1982-02-16
AU545274B2 (en) 1985-07-11
DE3061269D1 (en) 1983-01-13
FI71929B (fi) 1986-11-28
IT1133025B (it) 1986-07-09
GB2053218A (en) 1981-02-04
KR850000072B1 (ko) 1985-02-18
DK159770B (da) 1990-12-03
AU5969780A (en) 1981-01-08
ZA803880B (en) 1982-02-24
GB2053218B (en) 1984-01-25
IL60422A0 (en) 1980-09-16
JPH0154339B2 (fr) 1989-11-17
KR840004668A (ko) 1984-10-22
KR830002693A (ko) 1983-05-30
ZM5780A1 (en) 1983-11-21
IT8049108A0 (it) 1980-06-27
JPS5649335A (en) 1981-05-02
MW2380A1 (en) 1982-03-10
KR850000073B1 (ko) 1985-02-18
DK279780A (da) 1980-12-30
FI71929C (fi) 1987-03-09
FI802052A7 (fi) 1980-12-30
ZW14480A1 (en) 1982-03-17
DK159770C (da) 1991-04-22
HU190774B (en) 1986-11-28

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