OA09677A - Nucleoside derivatives - Google Patents

Nucleoside derivatives

Info

Publication number
OA09677A
OA09677A OA60286A OA60286A OA09677A OA 09677 A OA09677 A OA 09677A OA 60286 A OA60286 A OA 60286A OA 60286 A OA60286 A OA 60286A OA 09677 A OA09677 A OA 09677A
Authority
OA
OAPI
Prior art keywords
nucleoside derivatives
nucleoside
derivatives
Prior art date
Application number
OA60286A
Inventor
Jo Klaveness
Kjell Undheim
Original Assignee
Nycomed Imaging As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB909007651A external-priority patent/GB9007651D0/en
Priority claimed from GB909007566A external-priority patent/GB9007566D0/en
Priority claimed from GB909007650A external-priority patent/GB9007650D0/en
Application filed by Nycomed Imaging As filed Critical Nycomed Imaging As
Publication of OA09677A publication Critical patent/OA09677A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
OA60286A 1990-04-04 1992-10-02 Nucleoside derivatives OA09677A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB909007651A GB9007651D0 (en) 1990-04-04 1990-04-04 Nucleoside derivatives
GB909007566A GB9007566D0 (en) 1990-04-04 1990-04-04 Nucleoside derivatives
GB909007650A GB9007650D0 (en) 1990-04-04 1990-04-04 Nucleoside derivatives

Publications (1)

Publication Number Publication Date
OA09677A true OA09677A (en) 1993-05-15

Family

ID=27265029

Family Applications (1)

Application Number Title Priority Date Filing Date
OA60286A OA09677A (en) 1990-04-04 1992-10-02 Nucleoside derivatives

Country Status (6)

Country Link
EP (1) EP0523110A1 (en)
JP (1) JPH05505815A (en)
AU (1) AU7558491A (en)
CA (1) CA2079796A1 (en)
OA (1) OA09677A (en)
WO (1) WO1991015498A2 (en)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2073063A1 (en) * 1989-11-06 1991-05-07 Jo Klaveness Nucleoside derivatives
UA41261C2 (en) * 1992-06-22 2001-09-17 Елі Ліллі Енд Компані METHOD OF OBTAINING BETA-ANOMER-ENRICHED NUCLEOSIDES
YU43193A (en) * 1992-06-22 1997-01-08 Eli Lilly And Company 2'-DEOXY-2 ', 2'-DIFLUORO (4-SUBSTITUTED) PYRIMIDINE NUCLEOSIDS OF ANTIVIRUS AND ANTICANCEROGENIC ACTIVITY AND INTERMEDIATES
JPH0692987A (en) * 1992-09-17 1994-04-05 Tanabe Seiyaku Co Ltd Uridine derivative and process for producing the same
JPH11217396A (en) * 1998-01-30 1999-08-10 Ajinomoto Co Inc Production of nucleoside derivative
US6326507B1 (en) 1998-06-19 2001-12-04 Trustees Of Dartmouth College Therapeutic compounds and methods of use
US7435755B2 (en) 2000-11-28 2008-10-14 The Trustees Of Dartmouth College CDDO-compounds and combination therapies thereof
US7176237B2 (en) 2002-01-15 2007-02-13 The Trustees Of Dartmouth College Tricyclic-bis-enone derivatives and methods of use thereof
WO2004041203A2 (en) 2002-11-04 2004-05-21 Xenoport, Inc. Gemcitabine prodrugs, pharmaceutical compositions and uses thereof
CN1693309A (en) * 2005-04-18 2005-11-09 成都正开生物科技发展有限公司 N4 (substituted oxycarbonyl) 2',2'-bifluoro-2'-deoxycytidine derivate and application thereof
EP2094651A1 (en) 2006-11-17 2009-09-02 Trustees Of Dartmouth College Synthesis and biological activities of new tricyclic-bis-enones (tbes)
US8921340B2 (en) 2006-11-17 2014-12-30 Trustees Of Dartmouth College Methods for using synthetic triterpenoids in the treatment of bone or cartilage diseases or conditions
US8299046B2 (en) 2006-11-17 2012-10-30 Trustees Of Dartmouth College Synthetic triterpenoids and tricyclic-bis-enones for use in stimulating bone and cartilage growth
BRPI0907423A2 (en) 2008-01-11 2020-10-27 Reata Pharmaceuticals, Inc. synthetic triterpenoid compound for use in a method of improving kidney function in an individual, and use of that compound
MX2010011439A (en) 2008-04-18 2011-01-25 Reata Pharmaceuticals Inc Antioxidant inflammation modulators: c-17 homologated oleanolic acid derivatives.
KR101713140B1 (en) 2008-04-18 2017-03-08 리타 파마슈티컬스 잉크. Antioxidant inflammation modulators: oleanolic acid derivatives with saturation in the C-ring
WO2009146218A2 (en) 2008-04-18 2009-12-03 Reata Pharmaceuticals, Inc. Compounds including an anti-inflammatory pharmacore and methods of use
US8071632B2 (en) 2008-04-18 2011-12-06 Reata Pharmaceuticals, Inc. Antioxidant inflammation modulators: novel derivatives of oleanolic acid
JP5529851B2 (en) 2008-04-18 2014-06-25 リアタ ファーマシューティカルズ インコーポレイテッド Antioxidative inflammation modulator: oleanolic acid derivative with amino modification and other modifications in C-17
CN108686203A (en) 2012-04-04 2018-10-23 哈洛齐梅公司 Use the combination treatment of anti-hyaluronic acid agent and cancer target taxane
US8921419B2 (en) 2012-05-08 2014-12-30 Trustees Of Dartmouth College Triterpenoids and compositions containing the same
WO2016078160A1 (en) * 2014-11-17 2016-05-26 常州方圆制药有限公司 Cytidine derivative and application thereof
WO2016078397A1 (en) * 2014-11-17 2016-05-26 常州方圆制药有限公司 New type of cytidine derivative and application thereof
US20190351031A1 (en) 2018-05-16 2019-11-21 Halozyme, Inc. Methods of selecting subjects for combination cancer therapy with a polymer-conjugated soluble ph20
GR1009958B (en) * 2019-04-24 2021-03-18 ΕΝΟΡΑΣΙΣ ΑΝΩΝΥΜΗ ΕΜΠΟΡΙΚΗ ΕΤΑΙΡΕΙΑ ΦΑΡΜΑΚΕΥΤΙΚΩΝ ΚΑΙ ΙΑΤΡΙΚΩΝ ΥΛΙΚΩΝ ΚΑΙ ΜΗΧΑΝΗΜΑΤΩΝ με δ.τ. "ΕΝΟΡΑΣΙΣ Α.Ε." Gemcitabine derivatives and methods of forming gemcotabine derivatives
CN113906040B (en) * 2019-05-03 2024-06-14 拓臻制药公司 Compounds used to treat cancer
US20250282812A1 (en) * 2022-04-20 2025-09-11 Shanghai Institute Of Materia Medica , Chinese Academy Of Sciences Antiviral nucleoside analogue, and pharmaceutical composition and use thereof

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3651045A (en) * 1968-10-21 1972-03-21 Parke Davis & Co 9-(beta-d-arabinofuranosyl)adenine esters and methods for their production
DK149026C (en) * 1980-06-23 1986-07-07 Univ Minnesota METHOD OF ANALOGUE FOR THE PREPARATION OF ADENINNUCLEOSIDE DERIVATIVES
DE3100478A1 (en) * 1981-01-09 1982-08-12 Dr. Thilo & Co GmbH, 8021 Sauerlach 5'ESTERS OF PYRIMIDINE NUCLEOSIDES WITH ANTIVIRAL EFFECTIVENESS, METHOD FOR THE PRODUCTION AND MEDICINAL PRODUCTS THEREOF
US4495180A (en) * 1982-06-21 1985-01-22 Merck & Co., Inc. Prodrugs of Ara-A an antiviral agent
EP0104857A1 (en) * 1982-09-28 1984-04-04 Beecham Group Plc Deoxyuridine compounds, methods for preparing them and their use in medicine
DE3481191D1 (en) * 1983-07-20 1990-03-08 Teijin Ltd ANTINEOPLASTIC AGENT.
DE3650741T2 (en) * 1985-09-17 2000-10-12 The Wellcome Foundation Ltd., Greenford Combination of therapeutic nucleosides with other therapeutically active components.
US4751221A (en) * 1985-10-18 1988-06-14 Sloan-Kettering Institute For Cancer Research 2-fluoro-arabinofuranosyl purine nucleosides
US4780452A (en) * 1986-09-08 1988-10-25 Burroughs Wellcome Co. F-substituted-3-β-D-ribofuranosyl-3H-imidazo[4,5-b]pyridines and pharmaceutical compositions thereof
AU613026B2 (en) * 1987-03-24 1991-07-25 Nycomed As 2',3' dideoxyribofuranoxide derivatives
EP0329348B1 (en) * 1988-02-16 1995-07-12 Eli Lilly And Company 2',3'-Dideoxy-2',2'-difluoronucleosides
JPH02152976A (en) * 1988-05-06 1990-06-12 Bristol Myers Co Prodrug of 2',3'-didehydro-2',3'-dideoxynucleoside
US4900828A (en) * 1988-05-12 1990-02-13 Hoffmann-Laroche Inc. Intermediate compounds and an improved procedure for the synthesis of 2',3'-dideoxycytidine
EP0346108A3 (en) * 1988-06-09 1991-04-24 The Wellcome Foundation Limited Anti-infective nucleosides
EP0355031A3 (en) * 1988-08-17 1990-12-27 MATTHES, Eckart, Dr. Substituted pyrimidine nucleosides, process for their preparation and pharmaceutical compounds containing them
GB8823320D0 (en) * 1988-10-05 1988-11-09 Nycomed As Chemical compounds
GB8823319D0 (en) * 1988-10-05 1988-11-09 Nycomed As Chemical compounds
GB8920534D0 (en) * 1989-09-11 1989-10-25 Wellcome Found Antiviral compounds

Also Published As

Publication number Publication date
WO1991015498A2 (en) 1991-10-17
EP0523110A1 (en) 1993-01-20
AU7558491A (en) 1991-10-30
WO1991015498A3 (en) 1992-06-11
JPH05505815A (en) 1993-08-26
CA2079796A1 (en) 1991-10-05

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