OA11557A - 2-Aminopyridines containing fused ring substituents as nitric oxide synthase inhibitors. - Google Patents

2-Aminopyridines containing fused ring substituents as nitric oxide synthase inhibitors. Download PDF

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Publication number
OA11557A
OA11557A OA1200000325A OA1200000325A OA11557A OA 11557 A OA11557 A OA 11557A OA 1200000325 A OA1200000325 A OA 1200000325A OA 1200000325 A OA1200000325 A OA 1200000325A OA 11557 A OA11557 A OA 11557A
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OA
OAPI
Prior art keywords
alkyl
substituents
phenyl
independently
disease
Prior art date
Application number
OA1200000325A
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English (en)
Inventor
Lowe John Adams Iii
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Pfizer Prod Inc
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Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of OA11557A publication Critical patent/OA11557A/en

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    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/73—Unsubstituted amino or imino radicals
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    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/06—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with radicals, containing only hydrogen and carbon atoms, attached to ring carbon atoms
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
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    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Addiction (AREA)
  • Reproductive Health (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Psychology (AREA)
  • Immunology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Hematology (AREA)
  • Otolaryngology (AREA)
  • Emergency Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
OA1200000325A 1998-06-03 1999-05-07 2-Aminopyridines containing fused ring substituents as nitric oxide synthase inhibitors. OA11557A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8788198P 1998-06-03 1998-06-03

Publications (1)

Publication Number Publication Date
OA11557A true OA11557A (en) 2004-05-24

Family

ID=22207822

Family Applications (1)

Application Number Title Priority Date Filing Date
OA1200000325A OA11557A (en) 1998-06-03 1999-05-07 2-Aminopyridines containing fused ring substituents as nitric oxide synthase inhibitors.

Country Status (35)

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EP (1) EP1084109B1 (is)
JP (1) JP3444495B2 (is)
KR (1) KR20010052515A (is)
CN (1) CN1303379A (is)
AP (1) AP1208A (is)
AR (1) AR016724A1 (is)
AT (1) ATE287876T1 (is)
AU (1) AU765851B2 (is)
BG (1) BG105089A (is)
BR (1) BR9911615A (is)
CA (1) CA2334012C (is)
CO (1) CO5060509A1 (is)
DE (1) DE69923448T2 (is)
DZ (1) DZ2807A1 (is)
EA (1) EA003991B1 (is)
ES (1) ES2235475T3 (is)
GT (1) GT199900078A (is)
HR (1) HRP20000825A2 (is)
HU (1) HUP0102236A3 (is)
ID (1) ID27027A (is)
IL (1) IL139734A0 (is)
IS (1) IS5726A (is)
MA (1) MA24872A1 (is)
NO (1) NO20006042L (is)
NZ (1) NZ508057A (is)
OA (1) OA11557A (is)
PA (1) PA8473501A1 (is)
PE (1) PE20000554A1 (is)
PL (1) PL344699A1 (is)
SK (1) SK17912000A3 (is)
TN (1) TNSN99105A1 (is)
UY (1) UY25539A1 (is)
WO (1) WO1999062883A1 (is)
YU (1) YU73200A (is)
ZA (1) ZA993699B (is)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1341099A (zh) * 1999-02-25 2002-03-20 辉瑞产品公司 含有稠合环取代基的2－氨基吡啶
GB0004153D0 (en) 2000-02-23 2000-04-12 Astrazeneca Uk Ltd Novel use
GB0004152D0 (en) 2000-02-23 2000-04-12 Astrazeneca Uk Ltd Novel compounds
GB0004151D0 (en) 2000-02-23 2000-04-12 Astrazeneca Uk Ltd Novel use
GB0004149D0 (en) * 2000-02-23 2000-04-12 Astrazeneca Uk Ltd Novel compounds
SE0102640D0 (sv) 2001-07-31 2001-07-31 Astrazeneca Ab Novel compounds
UA105182C2 (ru) 2008-07-03 2014-04-25 Ньюрексон, Інк. Бензоксазины, бензотиазины и родственные соединения, которые имеют ингибирующую nos активность

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW432073B (en) * 1995-12-28 2001-05-01 Pfizer Pyrazolopyridine compounds
HN1996000101A (es) * 1996-02-28 1997-06-26 Inc Pfizer Terapia combinada para la osteoporosis
PT891332E (pt) * 1996-03-29 2004-07-30 Pfizer Derivados de 6-fenilpiridil-2-amina
HN1997000027A (es) 1996-12-06 1997-06-05 Pfizer Prod Inc Derivados de 6-fenil piridil - 2 amina
YU35699A (sh) * 1997-02-10 2002-06-19 Pfizer Products Inc. 2-amino-6-(2-supstituisan-4-fenoksi)-supstituisani piridini
HN1998000118A (es) * 1997-08-27 1999-02-09 Pfizer Prod Inc 2 - aminopiridinas que contienen sustituyentes de anillos condensados.

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IL139734A0 (en) 2002-02-10
HUP0102236A3 (en) 2003-01-28
ATE287876T1 (de) 2005-02-15
CO5060509A1 (es) 2001-07-30
PE20000554A1 (es) 2000-07-08
IS5726A (is) 2000-11-24
PL344699A1 (en) 2001-11-19
EP1084109B1 (en) 2005-01-26
AR016724A1 (es) 2001-07-25
YU73200A (sh) 2003-02-28
HUP0102236A2 (hu) 2001-11-28
EP1084109A1 (en) 2001-03-21
AU765851B2 (en) 2003-10-02
AU3438799A (en) 1999-12-20
AP9901558A0 (en) 1999-06-30
DE69923448D1 (de) 2005-03-03
SK17912000A3 (sk) 2001-09-11
BR9911615A (pt) 2001-02-06
KR20010052515A (ko) 2001-06-25
PA8473501A1 (es) 2000-09-29
GT199900078A (es) 2000-11-22
HRP20000825A2 (en) 2001-12-31
JP3444495B2 (ja) 2003-09-08
NO20006042L (no) 2001-01-31
ID27027A (id) 2001-02-22
EA200001143A1 (ru) 2001-06-25
EA003991B1 (ru) 2003-12-25
DE69923448T2 (de) 2005-12-29
DZ2807A1 (fr) 2003-12-01
CA2334012A1 (en) 1999-12-09
TNSN99105A1 (fr) 2005-11-10
MA24872A1 (fr) 1999-12-31
WO1999062883A1 (en) 1999-12-09
ES2235475T3 (es) 2005-07-01
BG105089A (en) 2001-09-28
CA2334012C (en) 2006-05-02
ZA993699B (en) 2000-12-01
NO20006042D0 (no) 2000-11-29
NZ508057A (en) 2003-07-25
JP2002516907A (ja) 2002-06-11
AP1208A (en) 2003-09-29
UY25539A1 (es) 2000-12-29
CN1303379A (zh) 2001-07-11

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