OA12352A - Tartrate salts of thiazolidinedione derivative. - Google Patents

Tartrate salts of thiazolidinedione derivative. Download PDF

Info

Publication number: OA12352A
Authority: OA; OAPI
Prior art keywords: tartrate; compound; accordance; ethoxy; methyl
Prior art date: 2000-08-04

Application number

OA1200300026A

Other languages

English (en)

Inventor

Bernadette Marie Choudary

Andrew Simon Craig

Tim Chien Ting Ho

Donald Colin Mackenzie

Deirdre O'keeffe

Original Assignee

Smithkline Beecham Plc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-08-04

Filing date

2001-08-03

Publication date

2006-05-16

2001-08-03 Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc

2006-05-16 Publication of OA12352A publication Critical patent/OA12352A/en

Links

150000003892 tartrate salts Chemical class 0.000 title description 3
150000001467 thiazolidinediones Chemical class 0.000 title 1
FEWJPZIEWOKRBE-LWMBPPNESA-L D-tartrate(2-) Chemical compound [O-]C(=O)[C@@H](O)[C@H](O)C([O-])=O FEWJPZIEWOKRBE-LWMBPPNESA-L 0.000 claims abstract description 51
150000001875 compounds Chemical class 0.000 claims abstract description 34
125000001301 ethoxy group Chemical group [H]C([H])([H])C([H])([H])O* 0.000 claims abstract description 13
238000004519 manufacturing process Methods 0.000 claims abstract description 4
239000007787 solid Substances 0.000 claims description 13
YASAKCUCGLMORW-UHFFFAOYSA-N Rosiglitazone Chemical compound C=1C=CC=NC=1N(C)CCOC(C=C1)=CC=C1CC1SC(=O)NC1=O YASAKCUCGLMORW-UHFFFAOYSA-N 0.000 claims description 8
238000000634 powder X-ray diffraction Methods 0.000 claims description 8
238000001237 Raman spectrum Methods 0.000 claims description 5
238000002329 infrared spectrum Methods 0.000 claims description 5
238000001460 carbon-13 nuclear magnetic resonance spectrum Methods 0.000 claims description 3
239000007909 solid dosage form Substances 0.000 claims description 2
239000000203 mixture Substances 0.000 abstract description 20
ZOBPZXTWZATXDG-UHFFFAOYSA-N 1,3-thiazolidine-2,4-dione Chemical compound O=C1CSC(=O)N1 ZOBPZXTWZATXDG-UHFFFAOYSA-N 0.000 abstract description 9
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract description 6
239000003814 drug Substances 0.000 abstract 1
239000012453 solvate Substances 0.000 abstract 1
239000000047 product Substances 0.000 description 12
FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 description 10
AUONNNVJUCSETH-UHFFFAOYSA-N icosanoyl icosanoate Chemical compound CCCCCCCCCCCCCCCCCCCC(=O)OC(=O)CCCCCCCCCCCCCCCCCCC AUONNNVJUCSETH-UHFFFAOYSA-N 0.000 description 10
KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 9
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FEWJPZIEWOKRBE-JCYAYHJZSA-L L-tartrate(2-) Chemical compound [O-]C(=O)[C@H](O)[C@@H](O)C([O-])=O FEWJPZIEWOKRBE-JCYAYHJZSA-L 0.000 description 8
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Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Diabetes (AREA)
General Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Hematology (AREA)
Obesity (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Cosmetics (AREA)

OA1200300026A 2000-08-04 2001-08-03 Tartrate salts of thiazolidinedione derivative. OA12352A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GBGB0019228.6A GB0019228D0 (en)	2000-08-04	2000-08-04	Novel pharmaceutical

Publications (1)

Publication Number	Publication Date
OA12352A true OA12352A (en)	2006-05-16

Family

ID=9897030

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
OA1200300026A OA12352A (en)	2000-08-04	2001-08-03	Tartrate salts of thiazolidinedione derivative.

Country Status (35)

Country	Link
US (1)	US20040048899A1 (es)
EP (1)	EP1305312B1 (es)
JP (1)	JP2004505972A (es)
KR (1)	KR100755173B1 (es)
CN (1)	CN1458931A (es)
AP (1)	AP1814A (es)
AT (1)	ATE393153T1 (es)
AU (1)	AU2001276509A1 (es)
BG (1)	BG107606A (es)
BR (1)	BR0112981A (es)
CA (1)	CA2417829A1 (es)
CZ (1)	CZ2003316A3 (es)
DE (1)	DE60133746T2 (es)
DK (1)	DK1305312T3 (es)
DZ (1)	DZ3467A1 (es)
EA (1)	EA004764B1 (es)
EC (1)	ECSP034469A (es)
ES (1)	ES2302506T3 (es)
GB (1)	GB0019228D0 (es)
HR (1)	HRP20030070A2 (es)
HU (1)	HUP0300777A3 (es)
IL (2)	IL154278A0 (es)
MA (1)	MA25898A1 (es)
MX (1)	MXPA03001087A (es)
NO (1)	NO324595B1 (es)
NZ (1)	NZ524032A (es)
OA (1)	OA12352A (es)
PL (1)	PL360703A1 (es)
PT (1)	PT1305312E (es)
SI (1)	SI1305312T1 (es)
SK (1)	SK1442003A3 (es)
UA (1)	UA76721C2 (es)
WO (1)	WO2002012234A1 (es)
YU (1)	YU16303A (es)
ZA (1)	ZA200300963B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
USRE39384E1 (en)	1993-09-01	2006-11-07	Smithkline Beecham P.L.C.	Substituted thiazolidinedione derivatives
AR047530A1 (es)	2004-02-04	2006-01-25	Novartis Ag	Formas de sal de 4-(4-metilpiperazin-1-ilmetil)-n-(4-metil-3-(4-piridin-3-il)pirimidin-2-ilamino)fenil)-benzamida
EP1763521A1 (en) *	2004-06-30	2007-03-21	Eli Lilly and Company	1- (indole-6-carbonyl-d-phenylglycinyl)-4- (l-methylpiperidin-4- yl) piperazine d-tartrate
US7435741B2 (en) *	2006-05-09	2008-10-14	Teva Pharmaceutical Industries, Ltd.	2-N{5-[[4-[2-(methyl-2-pyridinylamino) ethoxy] phenyl]methyl]-2,4-thiazolidinedione} butanedioic acid, methods of preparation and compositions with rosiglitazone maleate
GB0616574D0 (en) *	2006-08-21	2006-09-27	Glaxo Group Ltd	Compounds
DE102009053562A1 (de)	2009-11-18	2011-05-19	Alfred E. Tiefenbacher (Gmbh & Co. Kg)	Rosiglitazonsuccinat enthaltende pharmazeutische Zusammensetzung
CN102532122B (zh) *	2010-12-29	2015-12-02	开封制药(集团)有限公司	酒石酸罗格列酮的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0842925A1 (en) *	1987-09-04	1998-05-20	Beecham Group Plc	Substituted thiazolidinedione derivatives
US6288095B1 (en) *	1987-09-04	2001-09-11	Beecham Group P.L.C.	Compounds
GB9218830D0 (en) *	1992-09-05	1992-10-21	Smithkline Beecham Plc	Novel compounds
US5741803A (en) *	1992-09-05	1998-04-21	Smithkline Beecham Plc	Substituted thiazolidinedionle derivatives

2000
- 2000-08-04 GB GBGB0019228.6A patent/GB0019228D0/en not_active Ceased
2001
- 2001-03-08 UA UA2003020940A patent/UA76721C2/uk unknown
- 2001-08-03 JP JP2002518209A patent/JP2004505972A/ja not_active Withdrawn
- 2001-08-03 NZ NZ524032A patent/NZ524032A/en unknown
- 2001-08-03 IL IL15427801A patent/IL154278A0/xx active IP Right Grant
- 2001-08-03 MX MXPA03001087A patent/MXPA03001087A/es active IP Right Grant
- 2001-08-03 CN CN01815685A patent/CN1458931A/zh active Pending
- 2001-08-03 EA EA200300234A patent/EA004764B1/ru not_active IP Right Cessation
- 2001-08-03 PL PL36070301A patent/PL360703A1/xx not_active Application Discontinuation
- 2001-08-03 HR HR20030070A patent/HRP20030070A2/hr not_active Application Discontinuation
- 2001-08-03 DK DK01954162T patent/DK1305312T3/da active
- 2001-08-03 AT AT01954162T patent/ATE393153T1/de not_active IP Right Cessation
- 2001-08-03 SK SK144-2003A patent/SK1442003A3/sk unknown
- 2001-08-03 HU HU0300777A patent/HUP0300777A3/hu unknown
- 2001-08-03 SI SI200130830T patent/SI1305312T1/sl unknown
- 2001-08-03 AP APAP/P/2003/002738A patent/AP1814A/en active
- 2001-08-03 CA CA002417829A patent/CA2417829A1/en not_active Abandoned
- 2001-08-03 WO PCT/GB2001/003515 patent/WO2002012234A1/en not_active Ceased
- 2001-08-03 EP EP01954162A patent/EP1305312B1/en not_active Expired - Lifetime
- 2001-08-03 US US10/343,866 patent/US20040048899A1/en not_active Abandoned
- 2001-08-03 DZ DZ013467A patent/DZ3467A1/fr active
- 2001-08-03 OA OA1200300026A patent/OA12352A/en unknown
- 2001-08-03 YU YU16303A patent/YU16303A/sh unknown
- 2001-08-03 KR KR1020037001606A patent/KR100755173B1/ko not_active Expired - Fee Related
- 2001-08-03 ES ES01954162T patent/ES2302506T3/es not_active Expired - Lifetime
- 2001-08-03 BR BR0112981-3A patent/BR0112981A/pt not_active IP Right Cessation
- 2001-08-03 DE DE60133746T patent/DE60133746T2/de not_active Expired - Fee Related
- 2001-08-03 AU AU2001276509A patent/AU2001276509A1/en not_active Abandoned
- 2001-08-03 CZ CZ2003316A patent/CZ2003316A3/cs unknown
- 2001-08-03 PT PT01954162T patent/PT1305312E/pt unknown
2003
- 2003-01-31 NO NO20030507A patent/NO324595B1/no not_active IP Right Cessation
- 2003-02-03 IL IL154278A patent/IL154278A/en not_active IP Right Cessation
- 2003-02-03 MA MA27021A patent/MA25898A1/fr unknown
- 2003-02-04 EC EC2003004469A patent/ECSP034469A/es unknown
- 2003-02-28 BG BG107606A patent/BG107606A/bg unknown
- 2003-03-04 ZA ZA200300963A patent/ZA200300963B/en unknown

Also Published As

Publication number	Publication date
US20040048899A1 (en)	2004-03-11
IL154278A0 (en)	2003-09-17
ZA200300963B (en)	2004-04-19
HK1057359A1 (en)	2004-04-02
EA200300234A1 (ru)	2003-06-26
HUP0300777A2 (hu)	2003-11-28
DE60133746D1 (de)	2008-06-05
YU16303A (sh)	2006-01-16
AU2001276509A1 (en)	2002-02-18
IL154278A (en)	2009-02-11
PT1305312E (pt)	2008-06-19
AP2003002738A0 (en)	2003-03-31
WO2002012234A1 (en)	2002-02-14
EP1305312B1 (en)	2008-04-23
NO324595B1 (no)	2007-11-26
CA2417829A1 (en)	2002-02-14
GB0019228D0 (en)	2000-09-27
ATE393153T1 (de)	2008-05-15
SI1305312T1 (sl)	2008-08-31
KR20030022357A (ko)	2003-03-15
DZ3467A1 (fr)	2002-02-14
DK1305312T3 (da)	2008-07-28
ECSP034469A (es)	2003-06-25
CZ2003316A3 (en)	2004-03-17
AP1814A (en)	2008-01-04
HUP0300777A3 (en)	2005-04-28
KR100755173B1 (ko)	2007-09-03
SK1442003A3 (en)	2004-05-04
NZ524032A (en)	2004-07-30
DE60133746T2 (de)	2009-05-14
EA004764B1 (ru)	2004-08-26
HRP20030070A2 (en)	2005-02-28
CN1458931A (zh)	2003-11-26
NO20030507L (no)	2003-03-26
NO20030507D0 (no)	2003-01-31
JP2004505972A (ja)	2004-02-26
BR0112981A (pt)	2003-08-26
UA76721C2 (uk)	2006-09-15
PL360703A1 (en)	2004-09-20
BG107606A (bg)	2003-09-30
EP1305312A1 (en)	2003-05-02
MA25898A1 (fr)	2003-10-01
ES2302506T3 (es)	2008-07-16
MXPA03001087A (es)	2003-05-27

Publication	Publication Date	Title
OA12352A (en)	2006-05-16	Tartrate salts of thiazolidinedione derivative.
EP1315721B1 (en)	2006-10-25	A thiazolidinedione derivative and its use as antidiabetic
EP1305311B1 (en)	2008-01-16	Tartrate salt of thiazolidinedione derivative
EP1305310B1 (en)	2008-02-20	Tartrate salts of thiazolidinedione derivative
CA2417828A1 (en)	2002-02-14	Tartrate salts of thiazolidinedione derivative
US20040014752A1 (en)	2004-01-22	Sodium salts of 5-[4-]2-(n-methyl-N-(2-pyridyl) ethoxy]benzyl]thiazolidine-2,4-dione
US20040038968A1 (en)	2004-02-26	Thiazolidinedione derivative and its use as antidiabetic
US20040102485A1 (en)	2004-05-27	Tartrate salt of thiazolidinedione derivative
HK1057360B (en)	2009-01-23	Tartrate salts of thiazolidinedione derivative
HK1057359B (en)	2009-03-27	Tartrate salts of thiazolidinedione derivative
HK1057204B (en)	2007-05-04	A thiazolidinedione derivative and its use as antidiabetic
HK1057358B (en)	2008-05-30	Tartrate salt of thiazolidinedione derivative
HK1105818A (en)	2008-02-22	A thiazolidinedione derivative and its use as antidiabetic
AU2005229688A1 (en)	2005-11-24	Tartrate salts of thiazolidinedione derivative