OA12750A - Compositions pharmaceutiques à base de dérivés d'azétidine. - Google Patents

Compositions pharmaceutiques à base de dérivés d'azétidine. Download PDF

Info

Publication number: OA12750A
Authority: OA; OAPI
Prior art keywords: azetidine; general formula; azetidine derivative; composition according; pharmaceutical composition
Prior art date: 2001-12-21

Application number

OA1200400178A

Other languages

English (en)

French (fr)

Inventor

Sophie Cote

Valerie Bobineau

Maria-Teresa Peracchia

Original Assignee

Aventis Pharma Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-12-21

Filing date

2002-12-20

Publication date

2006-07-03

2002-12-20 Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa

2006-07-03 Publication of OA12750A publication Critical patent/OA12750A/fr

Links

150000001539 azetidines Chemical class 0.000 title claims abstract description 55
239000008194 pharmaceutical composition Substances 0.000 title claims abstract description 20
239000000203 mixture Substances 0.000 claims abstract description 116
230000000694 effects Effects 0.000 claims abstract description 22
238000009472 formulation Methods 0.000 claims abstract description 21
230000003389 potentiating effect Effects 0.000 claims abstract description 19
239000000546 pharmaceutical excipient Substances 0.000 claims abstract description 15
239000002736 nonionic surfactant Substances 0.000 claims abstract description 12
230000015572 biosynthetic process Effects 0.000 claims abstract description 11
239000000084 colloidal system Substances 0.000 claims abstract description 11
230000000087 stabilizing effect Effects 0.000 claims abstract description 10
230000003381 solubilizing effect Effects 0.000 claims abstract description 8
125000003118 aryl group Chemical group 0.000 claims abstract description 5
125000001072 heteroaryl group Chemical group 0.000 claims abstract description 5
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150000002367 halogens Chemical class 0.000 claims abstract description 4
125000004178 (C1-C4) alkyl group Chemical group 0.000 claims abstract description 3
125000000229 (C1-C4)alkoxy group Chemical group 0.000 claims abstract description 3
JCXJVPUVTGWSNB-UHFFFAOYSA-N Nitrogen dioxide Chemical compound O=[N]=O JCXJVPUVTGWSNB-UHFFFAOYSA-N 0.000 claims abstract description 3
OIQOAYVCKAHSEJ-UHFFFAOYSA-N 2-[2,3-bis(2-hydroxyethoxy)propoxy]ethanol;hexadecanoic acid;octadecanoic acid Chemical compound OCCOCC(OCCO)COCCO.CCCCCCCCCCCCCCCC(O)=O.CCCCCCCCCCCCCCCCCC(O)=O OIQOAYVCKAHSEJ-UHFFFAOYSA-N 0.000 claims description 25
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HONIICLYMWZJFZ-UHFFFAOYSA-N azetidine Chemical compound C1CNC1 HONIICLYMWZJFZ-UHFFFAOYSA-N 0.000 claims description 7
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229940045145 uridine Drugs 0.000 description 1
MWOOGOJBHIARFG-UHFFFAOYSA-N vanillin Chemical compound COC1=CC(C=O)=CC=C1O MWOOGOJBHIARFG-UHFFFAOYSA-N 0.000 description 1
FGQOOHJZONJGDT-UHFFFAOYSA-N vanillin Natural products COC1=CC(O)=CC(C=O)=C1 FGQOOHJZONJGDT-UHFFFAOYSA-N 0.000 description 1
235000012141 vanillin Nutrition 0.000 description 1
239000002076 α-tocopherol Substances 0.000 description 1
235000004835 α-tocopherol Nutrition 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Neurology (AREA)
Psychiatry (AREA)
Oil, Petroleum & Natural Gas (AREA)
Obesity (AREA)
Hematology (AREA)
Psychology (AREA)
Child & Adolescent Psychology (AREA)
Hospice & Palliative Care (AREA)
Diabetes (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Plural Heterocyclic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

OA1200400178A 2001-12-21 2002-12-20 Compositions pharmaceutiques à base de dérivés d'azétidine. OA12750A (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR0116638A FR2833842B1 (fr)	2001-12-21	2001-12-21	Compositions pharmaceutiques a base de derives d'azetidine

Publications (1)

Publication Number	Publication Date
OA12750A true OA12750A (fr)	2006-07-03

Family

ID=8870824

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
OA1200400178A OA12750A (fr)	2001-12-21	2002-12-20	Compositions pharmaceutiques à base de dérivés d'azétidine.

Country Status (31)

Country	Link
EP (1)	EP1458413B1 (es)
JP (1)	JP5021887B2 (es)
KR (1)	KR20040068308A (es)
CN (1)	CN100388918C (es)
AP (1)	AP1754A (es)
AR (1)	AR037687A1 (es)
AU (1)	AU2002364866B2 (es)
BR (1)	BR0215048A (es)
CA (1)	CA2470443A1 (es)
CO (1)	CO5590911A2 (es)
DE (1)	DE60233071D1 (es)
DK (1)	DK1458413T3 (es)
EA (1)	EA006510B1 (es)
EC (1)	ECSP045162A (es)
FR (1)	FR2833842B1 (es)
HR (1)	HRP20040575A2 (es)
HU (1)	HUP0402586A3 (es)
IL (1)	IL162563A0 (es)
MA (1)	MA27086A1 (es)
ME (1)	MEP16608A (es)
MX (1)	MXPA04005558A (es)
MY (1)	MY138172A (es)
NO (1)	NO20042781L (es)
NZ (1)	NZ533225A (es)
OA (1)	OA12750A (es)
PL (1)	PL203248B1 (es)
RS (1)	RS55504A (es)
TW (1)	TWI256304B (es)
UA (1)	UA77736C2 (es)
WO (1)	WO2003053431A2 (es)
ZA (1)	ZA200404338B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1498122A1 (en) *	2003-07-18	2005-01-19	Aventis Pharma S.A.	Semi-solid systems containing azetidine derivatives
EP1498123A1 (en) *	2003-07-18	2005-01-19	Aventis Pharma S.A.	Emulsifying systems containing azetidine derivatives
BRPI0507801A (pt)	2004-02-17	2007-07-10	Esteve Labor Dr	compostos de azetidina substituìda, processo para a preparação de compostos de azetidina substituìda, medicamento e uso de pelo menos um composto de azetidina substituìda
FR2879932B1 (fr) *	2004-12-27	2007-03-23	Aventis Pharma Sa	Formulations injectable ou administrable par voie orale de derives d'azetidine
NZ564759A (en)	2005-06-30	2011-08-26	Prosidion Ltd	GPCR agonists
AR064736A1 (es)	2007-01-04	2009-04-22	Prosidion Ltd	Agonistas de gpcr
BRPI0806498A2 (pt)	2007-01-04	2014-04-22	Prosidion Ltd	Agonistas gpcr piperidina
WO2008081208A1 (en)	2007-01-04	2008-07-10	Prosidion Limited	Piperidine gpcr agonists
GB0700122D0 (en)	2007-01-04	2007-02-14	Prosidion Ltd	GPCR agonists
CL2008000018A1 (es)	2007-01-04	2008-08-01	Prosidion Ltd	Compuestos derivados de heterociclos de nitrogeno y oxigeno, agonistas de gpcr; composicion farmaceutica que comprende a dicho compuesto; y uso del compuesto para el tratamiento de la obesidad, diabetes, sindrome metabolico, hiperlipidemia, toleranci
GB0720389D0 (en)	2007-10-18	2008-11-12	Prosidion Ltd	G-Protein Coupled Receptor Agonists
GB0720390D0 (en)	2007-10-18	2007-11-28	Prosidion Ltd	G-Protein coupled receptor agonists
FR2923719B1 (fr) *	2007-11-15	2009-11-20	Sanofi Aventis	Compositions pharmaceutiques a base de derives d'azetidine
FR2928149B1 (fr)	2008-02-29	2011-01-14	Sanofi Aventis	Composes derives d'azetidines, leur preparation et leur application en therapeutique
FR2946650B1 (fr) *	2009-06-16	2011-08-19	Sanofi Aventis	Esters derives d'azetidines, leur preparation et leur application en therapeutique.
UA153183U (uk)	2022-10-27	2023-05-31	Андрій Валерійович Максимов	Стаканчик для приготування напою

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GR73668B (es) *	1978-11-21	1984-03-28	Hoffmann La Roche
US5631365A (en) *	1993-09-21	1997-05-20	Schering Corporation	Hydroxy-substituted azetidinone compounds useful as hypocholesterolemic agents
HRP980026A2 (en) *	1998-01-20	1999-10-31	Pliva Pharm & Chem Works	1-izothiazolydinone derivatives of azetidine-2-ones, processes for the preparation and use thereof
WO2000003753A2 (en) *	1998-07-14	2000-01-27	Em Industries, Inc.	Microdisperse drug delivery systems
FR2783246B1 (fr) *	1998-09-11	2000-11-17	Aventis Pharma Sa	Derives d'azetidine, leur preparation et les medicaments les contenant
FR2805810B1 (fr) *	2000-03-03	2002-04-26	Aventis Pharma Sa	Compositions pharmaceutiques contenant des derives de 3- amino-azetidine, les nouveaux derives et leur preparation
FR2805818B1 (fr) *	2000-03-03	2002-04-26	Aventis Pharma Sa	Derives d'azetidine, leur preparation et les compositions pharmaceutiques les contenant
FR2805817B1 (fr) *	2000-03-03	2002-04-26	Aventis Pharma Sa	Compositions pharmaceutiques contenant des derives d'azetidine, les nouveaux derives d'azetidine et leur preparation
FR2814678B1 (fr) *	2000-10-04	2002-12-20	Aventis Pharma Sa	Association d'un antagoniste du recepteur cb1 et de sibutramine, les compositions pharmaceutiques les contenant et leur utilisation pour la traitement de l'obesite

2001
- 2001-12-21 FR FR0116638A patent/FR2833842B1/fr not_active Expired - Fee Related
2002
- 2002-12-02 AR ARP020104646A patent/AR037687A1/es unknown
- 2002-12-03 TW TW091135077A patent/TWI256304B/zh active
- 2002-12-20 MX MXPA04005558A patent/MXPA04005558A/es active IP Right Grant
- 2002-12-20 EP EP02801165A patent/EP1458413B1/fr not_active Expired - Lifetime
- 2002-12-20 AP APAP/P/2004/003066A patent/AP1754A/en active
- 2002-12-20 JP JP2003554188A patent/JP5021887B2/ja not_active Expired - Fee Related
- 2002-12-20 IL IL16256302A patent/IL162563A0/xx unknown
- 2002-12-20 HU HU0402586A patent/HUP0402586A3/hu unknown
- 2002-12-20 BR BR0215048-4A patent/BR0215048A/pt not_active IP Right Cessation
- 2002-12-20 WO PCT/FR2002/004514 patent/WO2003053431A2/fr not_active Ceased
- 2002-12-20 HR HR20040575A patent/HRP20040575A2/hr not_active Application Discontinuation
- 2002-12-20 NZ NZ533225A patent/NZ533225A/en not_active IP Right Cessation
- 2002-12-20 MY MYPI20024828A patent/MY138172A/en unknown
- 2002-12-20 ME MEP-166/08A patent/MEP16608A/xx unknown
- 2002-12-20 DE DE60233071T patent/DE60233071D1/de not_active Expired - Lifetime
- 2002-12-20 OA OA1200400178A patent/OA12750A/fr unknown
- 2002-12-20 UA UA20040706001A patent/UA77736C2/uk unknown
- 2002-12-20 CA CA002470443A patent/CA2470443A1/fr not_active Abandoned
- 2002-12-20 PL PL372708A patent/PL203248B1/pl not_active IP Right Cessation
- 2002-12-20 RS YUP-555/04A patent/RS55504A/sr unknown
- 2002-12-20 DK DK02801165T patent/DK1458413T3/da active
- 2002-12-20 CN CNB028248406A patent/CN100388918C/zh not_active Expired - Fee Related
- 2002-12-20 KR KR10-2004-7009708A patent/KR20040068308A/ko not_active Ceased
- 2002-12-20 AU AU2002364866A patent/AU2002364866B2/en not_active Ceased
- 2002-12-20 EA EA200400843A patent/EA006510B1/ru not_active IP Right Cessation
2004
- 2004-05-21 MA MA27694A patent/MA27086A1/fr unknown
- 2004-06-02 ZA ZA200404338A patent/ZA200404338B/en unknown
- 2004-06-17 CO CO04056913A patent/CO5590911A2/es not_active Application Discontinuation
- 2004-06-18 EC EC2004005162A patent/ECSP045162A/es unknown
- 2004-07-01 NO NO20042781A patent/NO20042781L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
CN100388918C (zh)	2008-05-21
CO5590911A2 (es)	2005-12-30
AU2002364866B2 (en)	2006-11-30
EA006510B1 (ru)	2005-12-29
MA27086A1 (fr)	2004-12-20
CN1602206A (zh)	2005-03-30
TW200301108A (en)	2003-07-01
HRP20040575A2 (en)	2004-10-31
TWI256304B (en)	2006-06-11
HK1070840A1 (zh)	2005-06-30
HUP0402586A3 (en)	2011-05-30
DK1458413T3 (da)	2009-11-23
WO2003053431A3 (fr)	2003-12-18
JP5021887B2 (ja)	2012-09-12
DE60233071D1 (de)	2009-09-03
AU2002364866A1 (en)	2003-07-09
PL203248B1 (pl)	2009-09-30
CA2470443A1 (fr)	2003-07-03
ECSP045162A (es)	2004-08-27
ZA200404338B (en)	2005-06-02
BR0215048A (pt)	2004-11-03
AP2004003066A0 (en)	2004-06-30
NO20042781L (no)	2004-09-20
HUP0402586A2 (hu)	2005-03-29
FR2833842B1 (fr)	2004-02-13
IL162563A0 (en)	2005-11-20
UA77736C2 (en)	2007-01-15
NZ533225A (en)	2007-02-23
JP2005516945A (ja)	2005-06-09
EA200400843A1 (ru)	2004-12-30
EP1458413A2 (fr)	2004-09-22
AP1754A (en)	2007-07-18
EP1458413B1 (fr)	2009-07-22
MEP16608A (en)	2010-06-10
MY138172A (en)	2009-04-30
KR20040068308A (ko)	2004-07-30
PL372708A1 (en)	2005-07-25
FR2833842A1 (fr)	2003-06-27
RS55504A (sr)	2007-06-04
AR037687A1 (es)	2004-12-01
WO2003053431A2 (fr)	2003-07-03
MXPA04005558A (es)	2004-12-06

Publication	Publication Date	Title
EP1458413B1 (fr)	2009-07-22	Compositions pharmaceutiques a base de derives d azetidine
CA2102777C (fr)	2004-09-07	Nouvelles compositions a base de derives de la classe des taxanes
US20110053903A1 (en)	2011-03-03	Pharmaceutical compositions based on azetidine derivatives
BE1009198A5 (fr)	1996-12-03	Compositions pharmaceutiques nouvelles contenant du propofol.
EP2269592B1 (fr)	2013-08-07	Composition pharmaceutique à base de progestérone micronisée et ses utilisations
JP2021523909A (ja)	2021-09-09	医薬製剤
US8293789B2 (en)	2012-10-23	Method of preparing a latanoprost opthalmic solution and the resulting solution
FR2814074A1 (fr)	2002-03-22	Nouvelles compositions estro-progestatives topiques a effet systemique
EP0758231A1 (fr)	1997-02-19	Compositions pharmaceutiques a base de derives de la classe des taxanes
LU87681A1 (fr)	1991-10-08	Compositions pharmaceutiques
WO2006070129A1 (fr)	2006-07-06	Formulations injectables ou administrables par voie orale de derives d'azetidine
FR2839888A1 (fr)	2003-11-28	Complexes d'inclusion de fenofibrate et de cyclodextrine et composition pharmaceutique les renfermant
JP2009513560A (ja)	2009-04-02	アゼチジン誘導体を含有する半固体系
JPH10265375A (ja)	1998-10-06	高級脂肪族アルコール製剤
HK1070840B (en)	2008-11-28	Pharmaceutical compositions based on azetidine derivatives
EP0433140B1 (fr)	1993-03-31	Nouvelle préparation pharmaceutique anti-allergique à action prolongée
FR2923719A1 (fr)	2009-05-22	Compositions pharmaceutiques a base de derives d'azetidine