OA12756A - 3-(Imidazolyl)-2-alkoxypropanoic acids as tafia inhibitors. - Google Patents

3-(Imidazolyl)-2-alkoxypropanoic acids as tafia inhibitors. Download PDF

Info

Publication number: OA12756A
Authority: OA; OAPI
Prior art keywords: préparation; hydrogen; compound according; nmr; 400mhz
Prior art date: 2002-01-22

Application number

OA1200400190A

Other languages

English (en)

Inventor

Charlotte Moira Norfo Allerton

David John Bull

Mark Edward Bunnage

Robert John Maguire

John Steele

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-01-22

Filing date

2003-01-10

Publication date

2006-07-03

2002-01-22 Priority claimed from GB0201389A external-priority patent/GB0201389D0/en

2002-01-29 Priority claimed from GB0202027A external-priority patent/GB0202027D0/en

2003-01-10 Application filed by Pfizer filed Critical Pfizer

2006-07-03 Publication of OA12756A publication Critical patent/OA12756A/en

Links

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Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

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Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Heart & Thoracic Surgery (AREA)
Biomedical Technology (AREA)
Cardiology (AREA)
Rheumatology (AREA)
Surgery (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Pain & Pain Management (AREA)
Hematology (AREA)
Diabetes (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Dermatology (AREA)
Physical Education & Sports Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

OA1200400190A 2002-01-22 2003-01-10 3-(Imidazolyl)-2-alkoxypropanoic acids as tafia inhibitors. OA12756A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB0201389A GB0201389D0 (en)	2002-01-22	2002-01-22	3-(imidazolyl)-2-alkoxypropanoic acids
GB0202027A GB0202027D0 (en)	2002-01-29	2002-01-29	3-(imidazolyl)-2-alkoxypropanoic acids

Publications (1)

Publication Number	Publication Date
OA12756A true OA12756A (en)	2006-07-03

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OA1200400190A OA12756A (en)	2002-01-22	2003-01-10	3-(Imidazolyl)-2-alkoxypropanoic acids as tafia inhibitors.

Country Status (24)

Country	Link
EP (1)	EP1467731A1 (is)
JP (1)	JP2005520811A (is)
KR (1)	KR20040077775A (is)
CN (1)	CN1620291A (is)
AP (1)	AP2004003084A0 (is)
AR (1)	AR038197A1 (is)
BR (1)	BR0307016A (is)
CA (1)	CA2472238A1 (is)
EA (1)	EA200400716A1 (is)
EC (1)	ECSP045200A (is)
HR (1)	HRP20040659A2 (is)
IL (1)	IL162677A0 (is)
IS (1)	IS7310A (is)
MA (1)	MA27167A1 (is)
MX (1)	MXPA04006573A (is)
NO (1)	NO20043457L (is)
OA (1)	OA12756A (is)
PA (1)	PA8563501A1 (is)
PE (1)	PE20030929A1 (is)
PL (1)	PL371487A1 (is)
TN (1)	TNSN04121A1 (is)
TW (1)	TW200302094A (is)
UY (1)	UY27615A1 (is)
WO (1)	WO2003061652A1 (is)

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WO2005051384A1 (en) *	2003-11-25	2005-06-09	Pfizer Limited	Stabilised pharmaceutical compositions
CA2604912A1 (en) *	2005-04-18	2006-10-26	Bayer Schering Pharma Aktiengesellschaft	Use of tafi inhibitors for enhanced myocardial reperfusion and facilitated pci
AU2009310841A1 (en)	2008-10-29	2010-05-06	Taisho Pharmaceutical Co., Ltd.	Compounds having TAFIa inhibitory activity
AU2009322342A1 (en) *	2008-12-05	2011-06-30	Merck Sharp & Dohme Corp.	Morpholinone compounds as factor IXa inhibitors
US8987242B2 (en)	2008-12-05	2015-03-24	Merck Sharp & Dohme Corp.	Morpholinone compounds as factor IXA inhibitors
KR20130006620A (ko) *	2010-03-18	2013-01-17	다이이찌 산쿄 가부시키가이샤	시클로프로판카르복실산 유도체
SG10201502026XA (en)	2010-03-18	2015-05-28	Daiichi Sankyo Co Ltd	Cycloalkyl-substituted imidazole derivative
RU2015156612A (ru)	2013-06-10	2017-07-17	Санофи	Макроциклические производные мочевины в качестве ингибиторов tafia, их получение и их применение в качестве фармацевтических средств
US20190117624A1 (en)	2016-03-29	2019-04-25	Daiichi Sankyo Company, Limited	Therapeutic agent for inflammatory bowel diseases
MY202326A (en)	2017-09-14	2024-04-24	Daiichi Sankyo Co Ltd	Compound having cyclic structure

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SE9901572D0 (sv) *	1999-05-03	1999-05-03	Astra Ab	New compounds
PT1311488E (pt) *	2000-08-17	2009-12-30	Pfizer Ltd	Imidazóis substituídos utilizados como inibidores de tafia

2003
- 2003-01-10 EP EP03700059A patent/EP1467731A1/en not_active Withdrawn
- 2003-01-10 EA EA200400716A patent/EA200400716A1/ru unknown
- 2003-01-10 IL IL16267703A patent/IL162677A0/xx unknown
- 2003-01-10 OA OA1200400190A patent/OA12756A/en unknown
- 2003-01-10 JP JP2003561596A patent/JP2005520811A/ja active Pending
- 2003-01-10 CA CA002472238A patent/CA2472238A1/en not_active Abandoned
- 2003-01-10 KR KR10-2004-7011370A patent/KR20040077775A/ko not_active Ceased
- 2003-01-10 PL PL03371487A patent/PL371487A1/xx unknown
- 2003-01-10 MX MXPA04006573A patent/MXPA04006573A/es unknown
- 2003-01-10 WO PCT/IB2003/000060 patent/WO2003061652A1/en not_active Ceased
- 2003-01-10 BR BR0307016-6A patent/BR0307016A/pt not_active IP Right Cessation
- 2003-01-10 CN CNA03802599XA patent/CN1620291A/zh active Pending
- 2003-01-10 HR HR20040659A patent/HRP20040659A2/hr not_active Application Discontinuation
- 2003-01-10 AP APAP/P/2004/003084A patent/AP2004003084A0/en unknown
- 2003-01-16 TW TW092100889A patent/TW200302094A/zh unknown
- 2003-01-17 PE PE2003000058A patent/PE20030929A1/es not_active Application Discontinuation
- 2003-01-20 UY UY27615A patent/UY27615A1/es not_active Application Discontinuation
- 2003-01-21 AR ARP030100165A patent/AR038197A1/es unknown
- 2003-01-22 PA PA20038563501A patent/PA8563501A1/es unknown
2004
- 2004-06-14 IS IS7310A patent/IS7310A/is unknown
- 2004-06-30 TN TNP2004000121A patent/TNSN04121A1/en unknown
- 2004-07-15 MA MA27786A patent/MA27167A1/fr unknown
- 2004-07-22 EC EC2004005200A patent/ECSP045200A/es unknown
- 2004-08-19 NO NO20043457A patent/NO20043457L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
IL162677A0 (en)	2005-11-20
UY27615A1 (es)	2003-08-29
IS7310A (is)	2004-06-14
TNSN04121A1 (en)	2006-06-01
KR20040077775A (ko)	2004-09-06
WO2003061652A8 (en)	2004-09-10
TW200302094A (en)	2003-08-01
AP2004003084A0 (en)	2004-09-30
PE20030929A1 (es)	2003-11-05
EP1467731A1 (en)	2004-10-20
MXPA04006573A (es)	2004-10-04
JP2005520811A (ja)	2005-07-14
CN1620291A (zh)	2005-05-25
AR038197A1 (es)	2005-01-05
MA27167A1 (fr)	2005-01-03
BR0307016A (pt)	2004-11-03
HRP20040659A2 (en)	2004-10-31
NO20043457L (no)	2004-08-19
WO2003061652A1 (en)	2003-07-31
PL371487A1 (en)	2005-06-13
CA2472238A1 (en)	2003-07-31
PA8563501A1 (es)	2004-08-31
ECSP045200A (es)	2004-08-27
EA200400716A1 (ru)	2004-12-30

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