OA13038A - Pryridyloxymethyl and benzisoxazole azabicyclic derivatives. - Google Patents

Info

Publication number

OA13038A

OA13038A OA1200500259A OA1200500259A OA13038A OA 13038 A OA13038 A OA 13038A OA 1200500259 A OA1200500259 A OA 1200500259A OA 1200500259 A OA1200500259 A OA 1200500259A OA 13038 A OA13038 A OA 13038A

Authority

OA

OAPI

Prior art keywords

pyridin

benzo

octahydro

pyrido

isoxazol

Prior art date

2003-03-12

Links

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• KTZQTRPPVKQPFO-UHFFFAOYSA-N 1,2-benzoxazole Chemical compound C1=CC=C2C=NOC2=C1 KTZQTRPPVKQPFO-UHFFFAOYSA-N 0.000 title abstract description 4
• 150000001875 compounds Chemical class 0.000 claims abstract description 209
• -1 aminomethylpyridyloxymethyl Chemical group 0.000 claims abstract description 46
• 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims abstract description 44
• 239000001257 hydrogen Substances 0.000 claims abstract description 44
• 229910052739 hydrogen Inorganic materials 0.000 claims abstract description 44
• 208000035475 disorder Diseases 0.000 claims abstract description 42
• 229910052757 nitrogen Inorganic materials 0.000 claims abstract description 35
• 125000004435 hydrogen atom Chemical group [H]* 0.000 claims abstract description 34
• IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims abstract description 31
• 229910052760 oxygen Inorganic materials 0.000 claims abstract description 24
• 229910052736 halogen Inorganic materials 0.000 claims abstract description 23
• QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims abstract description 22
• 239000001301 oxygen Substances 0.000 claims abstract description 22
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• 125000002887 hydroxy group Chemical group [H]O* 0.000 claims abstract description 14
• 229910052717 sulfur Inorganic materials 0.000 claims abstract description 13
• NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 claims abstract description 11
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• DYLIWHYUXAJDOJ-OWOJBTEDSA-N (e)-4-(6-aminopurin-9-yl)but-2-en-1-ol Chemical compound NC1=NC=NC2=C1N=CN2C\C=C\CO DYLIWHYUXAJDOJ-OWOJBTEDSA-N 0.000 claims abstract description 4
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• 125000004169 (C1-C6) alkyl group Chemical group 0.000 claims abstract 5
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• AFVFQIVMOAPDHO-UHFFFAOYSA-N methanesulfonic acid Substances CS(O)(=O)=O AFVFQIVMOAPDHO-UHFFFAOYSA-N 0.000 claims description 35
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