OA13247A - Phenyl or pyridyl amide coumpounds as prostaglandin E2 antagonists. - Google Patents

Phenyl or pyridyl amide coumpounds as prostaglandin E2 antagonists. Download PDF

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Publication number
OA13247A
OA13247A OA1200600068A OA1200600068A OA13247A OA 13247 A OA13247 A OA 13247A OA 1200600068 A OA1200600068 A OA 1200600068A OA 1200600068 A OA1200600068 A OA 1200600068A OA 13247 A OA13247 A OA 13247A
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OA
OAPI
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groups
carbon atoms
chloro
amino
group
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OA1200600068A
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English (en)
Inventor
Kanzunari Nakao
Yoshiyuki Okumura
Seiji Nukui
Tatsuya Yamagishi
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Pfizer
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Publication of OA13247A publication Critical patent/OA13247A/en

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    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C233/81—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C07C233/82—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/87—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom of a carbon skeleton containing six-membered aromatic rings
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
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CA2536870C (en) 2009-10-27
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