OA21899A - A method for controlling the growth of undesirable vegetation. - Google Patents

Abstract

Described herein is a method of controlling the growth of undesirable vegetation weedy Glycine max, the method including treating the locus at which control is desired with a synergistic composition including glufosinate combinations.

Description

A METHOD FOR CONTROLLING THE GROWTH OF UNDESIRABLE

VEGETATION

CROSS-REFERENCE TO RELATED APPLICATIONS

This application claims priority to Indian Patent Application No. IN 202121045719, filed October 07, 2021, which is incorporatcd hcrcin by référencé in its entircty.

FIELD OF THE DISCLOSURE

The présent disclosurc relates to a niethod of controlling the growth of undcsirable végétation. More particularly, the présent disclosure relates to a method of controlling the growth of weedy Glycine max with a synergistic combination/composition.

BACKGROUND

Wecds are undesirable plants that are detrimental to agriculture and significantly affect crop yields. Farmers use various types of herbicides to control wecds. Herbicides with varied modes of action arc gcncrally combincd, which allows for broader spectrum of control and managing résistance to herbicides.

Soybean is a widely cultivated food crop across the globe. Currently, there are about 24 species in the genus Glycine, only two of which (G. max and G. soja) are annuals. Soybean plants that hâve been genetically engineered to be résistant to the herbicides 2,4-D, glufosinate, and glyphosate generally grow as volunteer soybean in cultivation of various other crops such as corn, cotton, etc. Volunteer crop plants, in general, arc considcrcd to be weeds bccausc they can rcduce crop yield and quality and reduce harvesting efficiency. If glyphosate-resistant volunteer soybean populations are high and left uncontrolled, they may cause yield loss in crops. Volunteer soybeans serve as a réservoir for plant pathogens to survive between cropping seasons and increase inoculum of soil borne pathogens. Growers must apply altemate or additional non-glyphosate herbicides to achieve effective control of volunteer glyphosateresistant soybean plants in glyphosate-resistant corn ficlds and in glyphosate-resistant cotton fields. Howevcr, the combinations currently known are not sufficient to control the résistant and persistent weeds such as weedy Glycine max.

Additionally, the combination of herbicides may not always result in the desired effecl. Combinations of herbicides may resuit in an additive effect or an antagonistic effect. Il may also resuit in phytotoxicity to the crops making it an undesirable combination. Consequently, herbicides need to be carcfully sclccted so that (hey can be combined to offer a synergistic effect that would conirol weeds while having no phytoloxic effect on the crop and reducc the chances of the weeds dcveloping résistance to a particular herbicide.

Accordingly, there is, therefore, a need in the art for a method for protecting crops from weedy Glycine max using combinations that hâve advantageous properties such as a herbicidal combination that is synergistic, helps in résistance management, reduces dosage of herbicides used and a herbicidal combination that has excellent residual effects.

OBJECTIVE OF THE INVENTION

It is an objective of the présent disclosure to provide a method of controlling weedy Glycine max by application of a synergistic herbicidal combination.

It is an objective of the présent disclosure to providc a method of controlling weedy Glycine max, by application of a synergistic herbicidal combination comprising glufosinate and at least one herbicide selectcd from nitrophenyl ether, imidazolinonc, organophosphorous, dicarboximide, phenoxyacetic, pyridine, cyclohcxene oxime, aryloxyphenoxypropionic, triazolonc class of herbicides and/or uracil class of herbicides.

It is an objective of the présent disclosure to providc a method of controlling weedy Glycine max, by application of a synergistic herbicidal combination comprising glufosinate and at least two herbicides sclccted from nitrophenyl ether, imidazolinonc, organophosphorous, dicarboximide, phenoxyacetic, pyridine, cyclohcxene oxime, aryloxyphenoxypropionic, triazolone class of herbicides, and/or uracil class of herbicides.

It is an objective of the présent disclosure to providc a method of controlling weedy Glycine max in crop plants.

Il is an objective of (hc présent disclosure to provide a method of increasing yield in a crop by application of a synergistic hcrbicidal combination.

It is an objective of the présent disclosure to providc a method of improving the plant hcalth by application of a synergistic herbicidal combination.

SUMMARY

Dcscribcd herein are methods of controlling weedy Glycine max by application of a synergistic herbicidal combination.

In an aspect, a method of controlling the growth of undesirable végétation - weedy Glycine max comprises treating the locus at which control is desired with a synergistic composition comprising glufosinatc, and at least one herbicide selected from:

(a) nitrophenyl ether class herbicides;

(b) imidazolinone class herbicides;

(c) organophosphorous class herbicides;

(d) dicarboximide class herbicides;

(e) phenoxyacetic class herbicides;

(0 pyridine class herbicides;

(g) cyclohexenc oxime class herbicides;

(h) aryloxyphenoxypropionic class herbicides;

(i) triazolone class herbicides, and/or (j) uracil class herbicides.

In another aspect, a synergistic composition for control of weedy Glycine max comprises glufosinate, and at least one herbicide selected from:

(a) nitrophenyl ether class herbicides;

(b) imidazolinone class herbicides;

(c) organophosphorous class herbicides;

(d) dicarboximide class herbicides;

(e) phenoxyacetic class herbicides;

(f) pyridine class herbicides;

(g) cyclohexenc oxime class herbicides;

(h) aryloxyphenoxypropionic class herbicides;

(i) triazolone class herbicides; and/or (j) uracîl class herbicides.

In a prcfcrrcd embodimcnt. the glufosinate is L-glufosinatc.

In accordance with another aspect, the weight ratio of the composition comprising lufosinatc and the at least one herbicide ranges from 1:100 to 100:1.

In accordance with another aspect, the weight ratio of the composition comprising glufosinate and the at least one herbicide ranges from 1:75 to 75:1.

In accordance with another aspect, a method of controlling the growth of undesirablc végétation weedy Glycine max comprises treating the locus at which control is desired with a synergistic composition comprising glufosinate, an imidazolinonc class herbicide, and a triazolone class herbicide.

In accordance with yet another aspect, the weedy Glycine max is controllcd in a range of crops.

DETAILED DESCRIPTION

Discussed below are some représentative embodiments of the présent disclosure. The invention in its broader aspects is not limited to the spécifie details and représentative methods. Illustrative exemples are described in this section in connection with the embodiments and methods provided.

It is to be noted that, as used in the spécification, the singular forms a, an, and the include plural referents unless the contcxt clcarly dictâtes otherwise. Thus, for example, reference to a composition containing “a surfactant” includes a mixture of two or more surfactants. It should also be noted that the term ‘or” is generally employed in its sense including “and/or” unless the content clearly dictâtes otherwise. The terms “emulsifier” and “surfactant” mean csscntially the same thing and may be used interchangeably. Further, the terms “composition” or “formulation” also mean essentially the same thing and may be used interchangeably.

The expression of varions quantities in terms of “%” or “% w/w” means the percentage by weight of the total solution or composition unless otherwise specified. The présent disclosure, in ail its aspects, is described in detail as follows:

glufosinate (phosphinothricin; DL-homoalanin-4-yl(methyl)phosphinic acid) is a racemic phosphinico amino acid (Hoerlein, G. 1994; glufosinate (Phosphinothricin), a natural amino acid with unexpected herbicidal properties. Rev. of Environmental Contamination and Toxicology 138, 73 - 145). Ils ammonium sait (glufosinate-ammonium) is widely used as a non-selective herbicide and is the active ingrédient of the commercial herbicide formulations Basta™, Bustcr™, Challenge™, Conqucst™, Dash™, Final™, Finale™, Liberty™ and Ignite™. The L-isomer of glufosinate is a structural analogue of glutamate and, therefore, is a compétitive inhibitor of the enzyme glutamine synthetase (GS) of bacteria and plants (Bayer et al, 1972, Phosphinothricin and phosphinothricyl-alanyl-alanin. Helv. Chim. Acta 55, 224 239\ Leason et ai., 1982, Inhibition of pea leaf glutamine synthetase by methioninsulfoximine, Phosphinothricin and other glutamate analogs. J. Phytochem. 21, 855 - 857). The D-isomcr is not a GS inhibitor and is not herbicidally active.

L-O utùsinaît’

Chemical structures of D-glufosinate and L-glufosinate.

It has surprisingly been found by the présent inventors that weedy Glycine max can be compietely controlled by the combination of glufosinate and at least one herbicide selcctcd from:

(a) nitrophenyl ether class herbicides;

(b) imidazolinone class herbicides;

(c) organophosphorous class herbicides;

(d) dicarboximide class herbicides;

(e) phcnoxyacctic class herbicides;

(f) pyridine class herbicides;

(g) cyclohexene oxime class herbicides;

(h) aryloxyphenoxypropionic class herbicides;

(i) triazolone class herbicides; and/or (j) uracil class herbicides.

More surprisingly, it was found that this combination, of glufosinate and the second herbicide, provided a syncrgistic effect in conlrolling weedy Glycine max. The degree of synergistic cnhancemcnt in the efficacy of the above combination towards control of weedy Glycine max was unprcdictablc and unexpectcd.

As used hercin, the tenu “glufosinate” refers to any molécule which is a racemic phosphinico amino acid or a sait thereof. The tcrm also includes forms and isomers of glufosinate such as glufosînatc-p. L-glufosinate, D-glufosinate, and sodium, potassium or ammonium salts thereof. The agronomically acceptable salts such as monosodium sait, disodium sait, monopotassium sait, dipotassium sait, calcium sait, ammonium sait, -NH3(CH3)⁺ sait, -NfhfCHs)²* sait, NH(CH3)³⁺salt, -NHiCtfchiCjfWH)* sait. -NHsCCHsKCîFhOH/ sait and the like can be used. The term can gcncrically refer to any form of glufosinate or its sait such as solvatés, hydrates, anhydrous form, polymorph forms. pseudo polymorph forms, amorphous form or mixture thereof.

Preferably, (hc herbicide glufosinate used in any aspect or embodiment dcscribcd herein may be replaced by, or used intcrchangcably as, its L-isomer, i.e., L-glufosinate.

As used herein, the term “L-glufosinate” refers to the L-isomer of glufosinate or a sait thereof. The L-isomer of glufosinate is a structural analogue of glutamate and, therefore, is a compétitive inhibitor of the enzyme glutamine synthetase (GS) of bacteria and plants. The Lenantiomer of glufosinate acts by inhibition of glutamine synthetase thereby causing accumulation of toxic levels of ammonium ion and indircctly stopping photosynthesis. Il is also known as phosphinothricin or (S)-2-amino-4-(hydroxy(methyl)phosphonoyl)butanoic acid. The term very commonly covers dérivatives such as salts and esters of L-glufosinatc. The term can gcncrically refer to any form of L-glufosinale or its sait such as solvatcs, hydrates, anhydrous form, polymorph forms, pseudo polymorph forms, amorphous form or mixture thereof. The tenu “L-glufosinatc or a sait thereof’ encompasses any sait of L-glufosinate, préférable sodium, potassium and ammonium salts. The term may also refer to an isomeric (racemic) mixture of L-glufosinatc, D-glufosinatc and salts thereof, whcrein the content of Lglufosinatc or a sali thereof in the mixture is 70% or grcatcr, preferably 80% or greater and more preferably 90% or greater.

Therefore, in an embodiment. the preferred glufosinate herbicide is L-glufosinalc.

The term ‘weedy Glycine max' in the présent scope of discussion refers to a weedy soybean growing in fields whcrein other crops arc being grown. Il may be referred to as volunteer soybcan and comprises both wild-typc or recombinant varictics of soybcan. The term also includes résistant varieties of soybcan to other herbicides, particularly résistant to lhe herbicides 2,4-D, glufosinatc, and glyphosatc. The résistant varieties may bc naturally dcvcloped or genetically engineered to demonstrate the résistance phenotype. That is, weedy Glycine max is a weed as it is not the target crop.

The term ‘herbicide’ as used herein dénotés a compound which Controls or modifies the growth of plants. The term ‘herbicidally effective amounf indicates the quantity of such a compound or combination of such compounds which is capable of producing a controlling or modifying effect on the growth of plants. Controlling effccts include ail déviation from natural development, for cxample: killing, retardation, leaf burn, albinism, dwarfing etc. The term ‘plants’ refers to ail physical parts of a plant, including seeds, seedlings, saplings, roots, tubers, stems, stalks, foliage and fruits. The ‘locus’ is intended to include soil, seeds, and seedlings as wcll as cslablishcd végétation.

The présent disciosure, therefore, in an embodiment, provides a method of controlling the growth of undcsirablc végétation al a locus, the method comprising treating the locus with a synergistic combination comprising glufosinatc, and at least one herbicide selected from:

(a) nitrophenyl ether class herbicides;

(b) imidazolinone class herbicides;

(c) organophosphorous class herbicides;

(d) dicarboximide class herbicides;

(e) phenoxyacetic class herbicides;

(f) pyridine class herbicides;

(g) cyclohcxcne oxime class herbicides;

(h) aryloxyphenoxypropionic class herbicides;

(i) triazolone class herbicides;

(j) uracil class herbicides;

and combinations thereof, wherein the undesirable végétation is weedy Glycine max.

In a preferred embodiment. glufosinatc is L-glufosinatc.

In an embodiment. the présent disclosure provides a method of controlling the growth of| undesirablc végétation at a locus, the method comprising treating the locus with a synergistic[

I combination comprising L-glufosinatc. and at least one herbicide selected from:l (a) nitrophcnyl ether class herbicides;

(b) imidazolinone class herbicides;

(c) organophosphorous class herbicides;

(d) dicarboximîde class herbicides;

(c) phcnoxyacetic class herbicides;

(f) pyridinc class herbicides;

(g) cyclohexene oxime class herbicides;

(h) aryloxyphenoxypropionic class herbicides;

(i) triazolone class herbicides;

(j) uracil class herbicides;

and combinations thercof, wherein the undesirablc végétation is weedy Glycine max.

In an embodiment. the nitrophcnyl ether class herbicide is selected from the group consisting of oxyfluorfen. acifluorfen, aclonifen, bifenox, chlomcthoxyfen, chlornitrofcn, etnipromid, fluorodifen, fluoroglycofcn, fluoronitrofen, fomesafen, fucaomi, furyloxyfen, halosafcn, lactofen, nitrofen, nitrofluorfen, and combinations thcrcof.

In a preferred embodiment. the nitrophcnyl ether class herbicide is oxyfluorfen.

In an embodiment, the présent invention provides a synergistic combination comprising Lglufosinate, and oxyfluorfen for controlling the growth of undesirablc végétation at a locus.

In an embodiment. the imidazolinone class herbicide is selected from the group consisting of imazethapyr. imazamethabenz, imazamox, imazapic, imazapyr, imazaquin and combinations thereof.

In a preferred embodiment, the imidazolinone class herbicide is imazethapyr.

In an embodiment. the organophosphorous class herbicide is selected from the group consisting of glyphosatc, amiprofos-methyl, amiprophos, anilofos, bensulide, bilanafos, butamifos, clacyfos, 2,4-DEP, DMPA, EBEP, fosamîne, glufosinate-P, pipcrophos, and combinations thereof.

In a preferred embodiment. the organophosphorous class herbicide is glyphosate.

In an embodiment. the présent invention provides a synergistic combination comprising Lglufosinate, and glyphosate for controlling the growth of undesirable végétation at a locus.

In an embodiment, the dicarboximide class herbicide is selected from the group consisting of Humioxazin, cinidon-ethyl, flumezin, flumiclorac, flumipropyn, and combinations thereof.

In a preferred embodiment. the dicarboximide class herbicide is flumioxazin.

In an embodiment, the présent invention provides a synergistic combination comprising LI glufosinate, and flumioxazin for controlling the growth of undesirable végétation at a locus. l

In an embodiment, the phenoxyacetic class herbicide is selected from the group consisting of ¹ clacyfos, 22,4-D, 4-CPA (p-Chlorophenoxyacetic acid), 3,4-DA, MCPA (2-methyl-4chlorophenoxyacctic acid), MCPA-thiocthyl, 2,4,5-T, and combinations thereof.

In a preferred embodiment, the phenoxyacetic class herbicide is 2,4-D.

In an embodiment, the présent invention provides a synergistic combination comprising Lglufosinate, and 2,4-D for controlling the growth of undesirable végétation at a locus.

In an embodiment, pyridine class herbicide is selected from the group consisting of triclopyr, aminopyralid, cliodinatc, clopyralid, diflufenican, dithiopyr, florpyrauxifen. flufcnican, fluroxypyr, halauxifcn, haloxydinc, picloram, picolinafcn. pyriclor, pyroxsulam, thiazopyr, xyloxadine, and combinations thereof. !

i

In a preferred embodiment. the pyridine class herbicide is triclopyr.

In an embodiment, the présent invention provides a synergistic combination comprising L- i glufosinate. and triclopyr for controlling the growth of undesirable végétation at a locus.

In an embodiment, the cyclohexene oxime class herbicide is selected from the group consisting of clethodim, alloxydim, butroxydim, cloproxydim, cycloxydim, profoxydim. selhoxydim, tepraloxydim, tralkoxydim, and combinations thereof.

In a preferred embodiment. the cyclohexene oxime class herbicide is clethodim.

i

In an embodiment, the présent invention provides a synergistic combination comprising Lglufosinatc, and clethodim for controlling the growth of undcsirable végétation at a locus.

In an embodîmcnt, the aryloxyphcnoxypropionic class herbicide is selected from the group consisting of haloxyfop, chlorazifop, clodinafop, clofop, cyhalofop, diclofop, fenoxaprop, 5 fcnoxaprop-P, fcnlhiaprop, fluazifop, fluazifop-P, haloxyfop-P, isoxapyrifop, metamifop, propaquizafop, quizalofop, quizalofop P, trifop, and combinations thereof.

In a preferred embodiment, the aryloxyphcnoxypropionic class herbicide is haloxyfop.

In an embodiment, the présent invention provides a synergistic combination comprising Lglufosinalc, and haloxyfop for controlling the growth of undcsirable végétation at a locus.

In an embodiment. the triazolonc class herbicide is selected from the group consisting of carfcntrazone. amicarbazonc. bcncarbazonc, flucarbazone, ipfencarbazone, propoxycarbazone, sulfentrazonc, thicncarbazone and combinations thereof.

In a preferred embodiment, the triazolonc class herbicide is carfcntrazone.

In an embodiment, the présent invention provides a synergistic combination comprising L15 glufosinatc, and carfcntrazone for controlling the growth of undcsirable végétation at a locus.

In an embodiment, the uracil class herbicide is selected from the group consisting of bromacil, isocil, lenacil, terbaeil. bcnzfendizonc, butafenacil, cpyrifcnacil, flupropacil, saflufenacil, tiafenacil, and combinations thereof.

In a preferred embodiment. the uracil class herbicide is saflufenacil.

In an embodiment, the présent invention provides a synergistic combination comprising Lglufosinate, and saflufenacil for controlling the growth of undcsirable végétation at a locus.

In an embodiment, the présent disclosure provides a method of controlling weedy Glycine max at a locus by treating said locus with a combination of glufosinatc, and at least one herbicide, wherein the weight ratio of glufosinatc and the at least one herbicide ranges from 1:100 to 25 100:1.

In an embodiment, the présent disclosure provides a method of controlling weedy Glycine max at a locus by treating said locus with a combination of L-glufosinatc, and ai least onc herbicide, wherein the weight ratio of L-glufosinate and the at least onc herbicide ranges from 1:100 to 100:1.

In an cmbodimcnt, the présent disclosure provides a method of controlling weedy Glycine max at a locus by treating said locus with a combination of glufosinate, and at least one herbicide, wherein the weight ratio of glufosinate and the at least onc herbicide ranges from l :75 to 75: l.

In an cmbodimcnt, preferably, the weight ratio between glufosinate and the at least onc herbicide ranges from l :50 to 50: l.

More preferably, the weight ratio between glufosinate and the at least one herbicide ranges from l :25 to 25: l, more preferably l : 10 to ΙΟ: l.

In a preferred embodiment. the weight ratio between glufosinate and the at least one herbicide ranges from l:5 to 5: l, even more preferably l:2 to 2:l.

In an embodiment, the présent disclosure provides a method of controlling weedy Glycine max at a locus by treating said locus with a combination of glufosinate and at least one herbicide, wherein the weight ratio between glufosinate and the nîtrophcnyl ether class of herbicides ranges from I:l00to 100:1, spccifically l:75 to 75: l, more spccifically 1:50 to 50:1, even more spccifically 1:25 to 25:1. In a preferred embodiment, the weight ratio between glufosinate and the nitrophenyl ether class herbicide ranges from 1:10 to 10:1, preferably 1:5 to 5:1, more preferably 1:2 to 2:1.

In an embodiment, the présent disclosure provides a method of controlling weedy Glycine max at a locus by treating said locus with a combination of glufosinate, and at least one imidazolinone class herbicide, wherein the weight ratio of glufosinate and lhe imidazolinone classof herbicides ranges from l:100to 100:1, spccifically 1:75 to75:l, more spccifically 1:50 to 50:1, even more spccifically 1:25 to 25:1. In a preferred embodiment, the weight ratio between glufosinate and the imidazolinone class herbicide ranges from 1:10 to 10:1, preferably 1:5 to 5:1, more preferably 1:2 to 2:1.

In an embodiment, the présent disclosure provides a method of controlling weedy Glycine max at a locus by treating said locus with a combination of glufosinate, and at least onc herbicide, wherein lhe weight ratio of glufosinate and the imidazolinone class herbicide ranges from 2:5 to.5:2.

In an embodiment, the présent disclosure provides a method of controlling weedy Glycine max at a locus by treating said locus with a combination of glufosinate, and at least one dicarboximide class herbicide, wherein the weight ratio of glufosinate and the dicarboximidc class herbicide ranges from 1:100 to 100:1, spccifically 1:75 to 75:1, more spccifically 1:50 to

50:1, even more specifïcally 1:25 to 25:1. In a preferred embodiment, the weight ratio betweenj glufosînate and the dicarboximide class herbicide ranges from 1:10 to 10:1, preferably 1:5 toj

5:1.‘

In an embodiment, the présent disclosure provides a method of controlling weedy Glycine max at a locus by treating said locus with a combination of glufosînate, and at least one phenoxyacetic class herbicide, wherein the weight ratio of glufosînate and the phenoxyacetic class herbicide ranges from 1:100 to 100:1, specifïcally 1:75 to 75:1, more specifïcally 1:50 to 50:1, even more specifïcally 1:25 to 25:1. In a preferred embodiment, the weight ratio between glufosînate and the phenoxyacetic class herbicide ranges from 1:10 to 10:1, preferably 1:5 to 10 5:1.

In an embodiment, the présent disclosure provides a method of controlling weedy Glycine max at a locus by treating said locus with a combination of glufosînate, and at least one pyridine herbicide, wherein the weight ratio of glufosînate and the pyridine class of herbicides ranges from 1:100 to 100:1, specifïcally 1:75 to 75:1, more specifïcally 1:50 to 50:1, even more specifïcally 1:25 to 25:1. In a preferred embodiment, the weight ratio between glufosînate and the pyridine class of herbicides ranges from 1:10 to 10:1, preferably 1:5 to 5:1.

In an embodiment, the présent disclosure provides a method of controlling weedy Glycine max at a locus by treating said locus with a combination of glufosînate, and at least one cyclohexenei oxime class herbicide, wherein the weight ratio of glufosînate and the cyclohexene oxime class herbicide ranges from 1:100 to 100:1, specifïcally 1:75 to 75:1, more specifïcally 1:50 to 50:1,j even more specifïcally 1:25 to 25:1. In a preferred embodiment, the weight ratio between' glufosînate and the cyclohexene oxime class herbicide ranges from 1:10 to 10:1, preferably 1:5 lo5:l.

In an embodiment, the présent disclosure provides a method of controlling weedy Glycine max at a locus by treating said locus with a combination of glufosînate, and at least one aryloxyphenoxypropionic class herbicide, wherein the weight ratio of glufosînate and the aryloxyphenoxypropionic class herbicide ranges from 1:100 to 100:1, specifïcally 1:75 to 75:1, more specifïcally 1:50 to 50:1, even more specifïcally 1:25 to 25:1. In a preferred embodiment, the weight ratio between glufosînate and the aryloxyphenoxypropionic class herbicide ranges 30 from 1:10 to 10:1, preferably 1:5 (o 5:1.

In an embodiment, the présent disclosure provides a method of controlling weedy Glycine max al a locus by treating said locus with a combination of glufosînate, and at least one triazolone _____________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________j class herbicide, whcrcin the weight ratio of glufosinatc and (hc triazolone class herbicide ranges from 1:100 to 100:1, spécifie al ly 1:75 to 75:1, more specifically 1:50 to 50:1.

In an embodiment, the présent disclosure provides a method of controlling weedy Glycine max at a locus by treating said locus with a combination of glufosinatc, and at least one uracil class herbicide, wherein the weight ratio of glufosinatc and the uracil class herbicide ranges from 1:100 to 100:1, specifically 1:75 to 75:1, more specifically 1:50 to 50:1.

Further, it was also surprisingly found by the înventors that weedy Glycine max can be completely controllcd by the combination of glufosinatc, an imidazolinone class herbicide, and a triazolone class herbicide.

More surprisingly, it was found that this combination of glufosinatc, an imidazolinone class herbicide, and a triazolone class herbicide, actcd in a synergistic manner in controlling weedy Glycine max. The degree of synergistic enhancemenl in efficacy of the above combination towards control of weedy Glycine max was unpredictable and unexpected.

Thereforc, in an embodiment, the présent disclosure provides a method of controlling weedy Glycine max at a locus by treating said locus with a combination of glufosinatc, and at least two herbicides, whcrcin the composition comprises glufosinatc; an imidazolinone class herbicide, and a herbicide triazolone class herbicide.

In an embodiment, the présent disclosure provides a method of controlling weedy Glycine max at a locus by treating said locus with a combination of glufosinatc, and at least two herbicides, wherein the herbicide selected from the imidazolinone class of herbicides is imazethapyr, and wherein the herbicide selected from the triazolone class of herbicides is carfentrazone.

In an embodiment, the présent disclosure provides a method of controlling weedy Glycine max at a locus by treating said locus with a combination of glufosinatc, and at least two herbicides, wherein the weight ratio of glufosinatc, and one of the two herbicides ranges between 1:100 to 100:1. Preferably, the weight ratio of glufosinate. and one of the two herbicides ranges between 1:50 to 50:1, more preferably 1:25 to 25:1. In a yet another preferred embodiment. the weight ratio of glufosinatc, and one of the two herbicides ranges between 1:10 and 10:1, more preferably 1:5 and 5:1 and even more preferably 1:2 and 2:1.

In an embodiment, the présent disclosure provides a method of controlling weedy Glycine max at a locus by treating said locus with a combination of glufosinate, and at least two herbicides, wherein the weight ratio of the two herbicides ranges between 1:100 to 100:1. Preferably, the weight ratio of the two herbicides ranges between l:50 to 50: l, more preferably 1:25 to 25:1. In a yet another preferred embodimcnt, the weight ratio of the two herbicides ranges between 1:10 and 10:1, more preferably 1:5 and 5:1 and even more preferably 1:2 and 2:1.

Preferably, the présent disclosure provides a method of controlling weedy Glycine max at a locus by treating said locus with a combination of glufosinatc, imazethapyr and carfentrazonc, whcrein the weight ratio of glufosinate, imazethapyr, and carfentrazonc ranges between 1:10:10 to 10:1:1.

The terms “g ai/L” as used herein dénotés the concentration of the respective active ingrédient in “grams” présent “per litre” of the composition.

The terms “g ai/h” as used herein dénotés the concentration of the respective active ingrédient in “grams” applied “per hectare” of the crop field.

In an embodiment, the présent disclosure provides a method of controlling weedy Glycine max at a locus by treating said locus with a combination of glufosinatc, and at least one herbicide in a composition, whercin the composition comprises glufosinate in an amount in the range of 100 to 400 g ai/L, preferably 180 to 380 g ai/L, more preferably 250 to 350 g ai/L. In a preferred embodiment, the composition comprises 280 g ai/L of glufosinate.

In an embodiment, the présent disclosure provides a method of controlling weedy Glycine max at a locus by treating said locus with a combination of glufosinate, and at least one herbicide, whcrein glufosinate is applied at an application rate of 50- 350 g ai/h, preferably 100 g ai/h (o 250 g ai/h.

In an embodiment, the présent disclosure provides a method of controlling weedy Glycine max at a locus by treating said locus with a combination of L-glufosinate, and at least one herbicide in a composition, whcrein the composition comprises L-glufosinate in an amount in the range of 100 to 400 g ai/L, preferably 180 to 380 g ai/L, more preferably 250 to 350 g ai/L. In a preferred embodiment, the composition comprises 280 g ai/L of L-glufosinatc.

In an embodiment, the présent disclosure provides a method of controlling weedy Glycine max at a locus by treating said locus with a combination of L-glufosinatc, and al least onc herbicide, wherein L-glufosinate is applied at an application rate of 50- 350 g ai/h, preferably 100 g ai/h to 250 g ai/h.

In an embodiment, the présent disclosure provides a method of controlling wccdy Glycine max at a locus by trcating said locus with a combination of glufosinate, and at least one herbicide in a composition, wherein the composition comprises glufosinate and at least one nitrophcnyl cther class herbicide, and wherein the nitrophcnyl ether class herbicide is présent in the composition in an amount in the range of 100 to 400 g ai/L, preferably 140 to 340 g ai/L, more preferably 200 to 250 g ai/L.

In an embodiment, the présent disclosure provides a method of controlling weedy Glycine max at a locus by trcating said locus with a combination of glufosinate, and at least one herbicide, wherein the at least one herbicide is a nitrophcnyl cther class herbicide and is applicd at an application rate of 5-250 g ai/h, preferably at a rate of 50-150 g ai/h and more preferably at a rate of 75 125 g ai/h.

In an embodiment, the présent disclosure provides a method of controlling weedy Glycine max at a locus by trcating said locus with a combination of glufosinate, and at least one herbicide in a composition, wherein the composition comprises glufosinate and the at least one imidazolinone class herbicide, and wherein the composition contains an imidazolinonc class herbicide in an amount in the range of 10 to 250 g ai/L, preferably 50 -200 g ai/L, more preferably 75 -125 g ai/L.

In an embodiment, the présent disclosure provides a method of controlling weedy Glycine max at a locus by treating said locus with a combination of glufosinate, and al least onc herbicide, wherein the at least one herbicide is an imidazolinone class herbicide and is applicd ai an application rate of 5-200 g ai/h, preferably at a rate of 20 to 150 g ai/h and more preferably at a rate of 50 - 100 g ai/h.

In an embodiment, the présent disclosure provides a method of controlling weedy Glycine max at a locus by trcating said locus with a combination of glufosinate, and at least one herbicide in a composition, wherein the composition comprises glufosinate and the at least one organophosphorous class herbicide, and wherein the composition contains an organophosphorous class herbicide in an amount in the range of 200 to 1000 g ai/L, preferably 400 to 800 g ai/L, more preferably 500 - 700 g ai/L.

In an embodiment, the présent disclosure provides a method of controlling weedy Glycine max at a locus by trcating said locus with a combination of glufosinate, and at least onc herbicide, wherein the at least one herbicide is an organophosphorous class herbicide and is applicd at an application rate of 100-800 g ai/h, preferably at a rate of 200 - 500 g ai/h, more preferably 300400 g ai/h.

In an embodiment. the présent disclosurc provides a method of controlling weedy Glycine max at a locus by treating said locus with a combination of glufosinate, and at least one herbicide 5 in a composition, wherein the composition comprises glufosinate and the at least one dicarboximidc class herbicide, and wherein the composition contains dicarboximidc class herbicide in an amount in the range of 200 - 800 g ai/L, preferably 300 to 700 g ai/L. more preferably 400-600 g ai/L.

In an embodiment, the présent disclosurc provides a method of controlling weedy Glycine max 10 at a locus by treating said locus with a combination of glufosinate, and at least one herbicide, wherein the al least one herbicide is a dicarboximidc class herbicide, and is applied at an application rate of Ito 200 g ai/h, preferably 5-100 g ai/h, preferably at a rate of 10 - 50 g ai/h.

In an embodiment. the présent disclosurc provides a method of controlling weedy Glycine max at a locus by treating said locus with a combination of glufosinate, and at least one herbicide 15 in a composition, wherein the composition comprises glufosinate and the at least one phcnoxyacctic class herbicide, and wherein the composition contains the phenoxyacetic class herbicide in an amount in the range of 400 to 1200 g ai/L, preferably 600 - 1000 g ai/L, more preferably 750 - 850 g ai/L.

In an embodiment, the présent disclosurc provides a method of controlling weedy Glycine max 20 at a locus by treating said locus with a combination of glufosinate, and at least one herbicide, wherein the at least one herbicide is a phenoxyacetic class herbicide, and is applied at an application rate of 50 - 400 g ai/h, preferably 100 - 300 g ai/h, preferably at a rate of 150-250 g ai/h.

In an embodiment, the présent disclosurc provides a method of controlling weedy Glycine max 25 at a locus by treating said locus with a combination of glufosinate, and at least one herbicide in a composition, wherein the composition comprises glufosinate and the at least one pyridine class herbicide, wherein the composition contains the pyridine class herbicide in an amount in the range of 300 - 1000 g ai/L, preferably 400 to 900 g ai/L, more preferably 500 to 750 g ai/L.

In an embodiment, the présent disclosurc provides a method of controlling weedy Glycine max 30 at a locus by treating said locus with a combination of glufosinate, and at least one herbicide, wherein the at least one herbicide is a pyridine class of herbicides, and is applied at an application rate of 50-500 g ai/h, preferably at a rate of 100-400 g ai/h and more preferably 200-350 g aî/h.

in an embodiment, the présent disclosurc provides a method of controlling weedy Glycine max at a locus by treating said locus with a combination of glufosinate, and at least onc herbicide in a composition, wherein the composition comprises glufosinate and the at least onc cyclohexene oxime class herbicide, and wherein the composition has the cyclohexcne oxime class herbicide in an amount in the range of 100 - 400 g ai/L. preferably 150 to 350 g ai/L, preferably 200-300 g ai/L.

In an embodiment, the présent disclosurc provides a method of controlling weedy Glycine max at a locus by treating said locus with a combination of glufosinate, and al least one herbicide, wherein the at least one herbicide is a cyclohexene oxime class of herbicides, and is applied at an application rate of 1-150 g ai/h, preferably at a rate of 10 - 100 g ai/h, more preferably 2575 g ai/h.

In an embodiment, the présent disclosurc provides a method of controlling weedy Glycine max at a locus by treating said locus with a combination of glufosinate, and at least onc herbicide in a composition, wherein the composition comprises glufosinate and the at least one aryloxyphenoxypropionic class herbicide, and wherein the composition has the aryloxyphenoxypropionic class herbicide in an amount in the range of 1 to 250 g ai/L, preferably 10 - 200 g ai/L and more preferably 50 - 150 g ai/L.

In an embodiment, the présent disclosurc provides a method of controlling weedy Glycine max at a locus by treating said locus with a combination of glufosinate, and al leasl one herbicide, wherein the at leasl one herbicide is an aryloxyphenoxypropionic class herbicide, and is applied at an application rate of 1 -150 g ai/h, preferably at a rate of 10 - 100g ai/h, and more preferably at a rate of 25 - 75 g ai/h.

In an embodiment. the présent disclosurc provides a method of controlling weedy Glycine max at a locus by treating said locus with a combination of glufosinate, and al least one herbicide in a composition, wherein the composition comprises glufosinate and the at least onc triazolone class herbicide, wherein the composition has the triazolone class herbicide in an amount in the range of 100 - 800 g ai/L, preferably 200 to 600 g ai/L, more preferably preferably 300 to 500 g ai/L,

In an embodiment, lhe présent disclosure provides a method of controlling weedy Glycine max at a locus by treating said locus with a combination of glufosinate, and al least one herbicide, wherein the at least one herbicide is a triazolone class herbicide is applicd at an application rate of 0.5-100 g ai/h, preferably at a rate of l - 50 g ai/h, more preferably 2-30 g ai/h.

In an embodiment. the present disclosure provides a method of controlling weedy Glycine max at a locus by treating said locus with a combination of glufosinate, and at least one herbicide in a composition, wherein the composition comprises glufosinate and the at least one uracil class herbicide, wherein the composition has the uracil class herbicide in an amount in the range of l — 1000 g ai/L, preferably 50 to 800 g ai/L.

In an embodiment, the present disclosure provides a method of controlling weedy Glycine max at a locus by treating said locus with a combination of glufosinate, and at least one herbicide, wherein the at least one herbicide is a uracil class herbicide is applicd al an application rate of 10-150 g ai/h, preferably at a rate of 20-70 g ai/h.

The compositions of the present disclosure can be used in agricultural lands such as fields, paddy fields, lawns and orchards or in non-agricultural lands. The présent disclosure may be used to control diseases in agricultural lands for cultivating the plants without any phytotoxicity to the plant. Examples of the crops on which the present compositions may bc used include but arc not limited to corn, rice, wheat, barley, rye, oat, sorghum, cotton, soybean, peanut, buckwheat, beet, rapeseed. sunflower, sugar cane, tobacco, etc.; vegetables: solanaceous vegetables such as eggplanl. tomato, pimento, pepper, polato, etc., cucurbit vegetables such as cucumbcr, pumpkin, zucchini, water melon, melon, squash, etc., crucifcrous vegetables such as radish, white turnip, horseradish, kohlrabi, Chinese cabbage, cabbage, leaf mustard, broccoli, cauliflower, etc., astcraceous vegetables such as burdock, crown daisy, artichoke, lettuce, etc, liliaceous vegetables such as green onion, onion, garlic, and asparagus, ammiaceous vegetables such as carrot, parsley, celery, parsnip, etc., chenopodiaceous vegetables such as spinach, Swiss chard, etc., lamiaceous vegetables such as Perilla frutescens, mint, basil, etc, slrawberry, sweet polato, Dioscorea japonica. colocasia, etc., flowers, foliage plants, turf grasses, fruits: pome fruits such apple, pear, quince, etc, stone fleshy fruits such as peach, plum. nectarine, Prunus munie, cherry fruit, apricot, prune, etc., citrus fruits such as orange, lemon, rime, grapefruit, etc., nuts such as chestnuts, walnuts, hazelnuls, almond, pistachio, cashew nuts, macadamia nuts, etc. bernes such as blueberry, cranberry, blackberry, raspberry, etc., grape, kaki fruit, olive, plum. banana. coffee, date palm, coconuts, etc., trocs other than fruit trees; tea, mulberry, flowering plant, trees such as ash, bîrch, dogwood, Eucalyptus, Ginkgo biloba. lilac, maple, Quercus, poplar, Judas tree, Liquidambar formosana, plane tree, zelkova, Japanese arborvitac, fir wood, hcmlock, juniper, Pinus, Picea, and Taxus cuspidatc. etc.

In an embodiment, the présent disclosure provides a synergistic composition for controlling weedy Glycine max comprising glufosinatc and at least one herbicide selected from:

(a) nitrophenyl ether class herbicides;

(b) imidazolinone class herbicides;

(c) organophosphorous class herbicides;

(d) dicarboximide class herbicides;

(e) phenoxyacetic class herbicides;

(f) pyridine class herbicides;

(g) cyclohexenc oxime class herbicides;

(h) aryloxyphenoxypropionic class herbicides;

(i) triazolone class herbicides;

(j) uracil class herbicides, and combinations thereof.

In a preferred embodiment. the glufosinate is L-glufosinate.

Therefore, in an embodiment, the présent disclosure provides a synergistic composition for controlling weedy Glycine max comprising L-glufosinate and at least one herbicide selected from:

(a) nitrophenyl ether class herbicides;

(b) imidazolinone class herbicides;

(c) organophosphorous class herbicides;

(d) dicarboximide class herbicides;

(e) phenoxyacetic class herbicides;

(f) pyridine class herbicides;

(g) cyclohexene oxime class herbicides;

(h) aryloxyphenoxypropionic class herbicides;

(i) triazolone class herbicides;

(j) uracil class herbicides, and combinations thereof.

In an embodimenl, the weight ratio of glufosinate and the at least one herbicide ranges from l : 100 to 100: l.

In an embodiment, the weight ratio of L-glufosinatc and the at least one herbicide ranges from 1:100 to 100:1.

In another embodiment, the weight ratio of glufosinate and the at least one herbicide ranges from 1:75 to75:l.

In an embodiment, the weight ratio between glufosinate and the at least one herbicide ranges from 1:50 to 50:1.

In an embodiment, the weight ratio between glufosinate and the at least one herbicide ranges from 1:25 to 25:1. more preferably 1:10 to 10:1.

In an embodiment, the weight ratio between glufosinate and the at least one herbicide ranges from 1:5 to 5:1.

In an embodiment, the weight ratio between glufosinate and the at least one herbicide ranges from 1:2 to 2:1.

In an embodiment, glufosinate is présent in the composition in an amount in the range of 100 to 400 g ai/L. preferably 180 to 380 g ai/L

In an embodiment. the al least one herbicide selected from (a) the nitrophenyl ether class herbicide is présent in an amount in the range of 100 to 400 g ai/L, preferably 140 to 340 g ai/L;

(b) the imidazolinonc class herbicide is présent in an amount in the range of 10 to 250 g ai/L. preferably 50 - 200 g ai/L;

(c) the organophosphorous class herbicide is présent in an amount in the range of 200 to 1000 g ai/L. preferably 400 to 800 g ai/L;

(d) the dicarboximide class herbicide is présent in an amount in the range of 200 - 800 g ai/L. preferably 300 to 700 g ai/L;

(e) the phenoxyacetic class herbicide is présent in an amount in the range of 400 to 1200 g ai/L. preferably 600 - 1000 g ai/L;

(f) the pyridine class herbicide is présent in an amount in the range of 300 - 1000 g ai/L. preferably 400 to 900 g ai/L;

(g) the cyclohexene oxime class herbicide is présent in an amount in the range of 100 - 400 g ai/L, preferably 150 to 350 g ai/L;

(h) the aryloxyphenoxypropionic class herbicide is présent in an amount in the range of l to 250 g ai/L, preferably 10 - 200 g ai/L;

(i) the triazolone class herbicide is présent in an amount in the range of 100 — 800 g ai/L, preferably 200 to 600 g ai/L; and/or (j) the uracil class herbicide is présent in an amount in the range of l - 1000 g ai/L, preferably 50 to 800 g ai/L.

In another embodiment, the présent disclosure provides a syncrgistic composition for controlling weedy Glycine max comprising glufosinate; an imidazolinonc class herbicide, and a triazolone class herbicide.

In a preferred embodiment, the herbicide selected from the herbicide selected from the imidazolinone class herbicides is imazethapyr, and wherein the herbicide selected from the triazolone class herbicides is carfcntrazone.

In an embodiment, the herbicide selected from the imidazolinone class herbicides, and the herbicide selected from the triazolone class herbicides arc présent in the composition in a ratio of l : 100 ίο 100:1, more preferably 1:10 to 10:1.

In an embodiment, the compositions of the présent disclosure additionally comprise one or more agrochemically suitable excipient such as adjuvants, additives, or carrier along with other ingrédients such as surfactants.

In an embodiment, the présent invention provides a syncrgistic composition for controlling weedy Glycine max comprising glufosinate, at least one herbicide selected from:

(a) nitrophenyl ether class herbicides;

(b) imidazolinone class herbicides;

(c) organophosphorous class herbicides;

(d) dicarboximide class herbicides;

(e) phenoxyacetic class herbicides;

(f) pyridine class herbicides;

(g) cyclohexene oxime class herbicides;

(h) aryloxyphenoxypropionic class herbicides;

(i) triazolone class herbicides;

(j) uracil class herbicides, and combinations thereof;

and at least one agrochemically suitable excipient.

In an embodiment, the présent invention provides a synergistîc composition for controlling weedy Glycine max comprising L-glufosinate, at least one herbicide selected from:

(k) nitrophenyl ether class herbicides;

(!) imidazolinone class herbicides;

(m)organophosphorous class herbicides;

(n) dicarboximide class herbicides;

(o) phenoxyacetic class herbicides;

(p) pyridinc class herbicides;

(q) cyclohexene oxime class herbicides;

(r) aryloxyphenoxypropionic class herbicides;

(s) triazolone class herbicides;

(t) uracil class herbicides, and combinations thereof;

and at least one agrochemically suitable excipient.

The agrochemically suitable excipient may be any one or a combination of adjuvants, cosolvents, surfactants, colorants, dispersants, cmulsifiers, thickeners, antifreeze agents, bîoeides, anti-foam agents, stabilizers, wetting agents or a mixture thereof which may be optionally added to the compositions of the présent disclosure.

The surfactants may be selected from non-ionic, anionic or cationic surfactants, and combinations thereof.

Examples of nonionic surfactants include polyarylphcnol polycthoxy ethers, polyalkylphenol polyethoxy ethers, polyglycol ether dérivatives of saturated fatty acids, polyglycol ether dérivatives of unsaturated fatty acids, polyglycol ether dérivatives of aliphatic alcohols, polyglycol ether dérivatives of cycloaliphatic alcohols, fatty acid esters of polyoxyethylene sorbitan, alkoxylated vegetable oils, alkoxylatcd acetylenic diols, polyalkoxylated alkylphenols, fatty acid alkoxylates, sorbitan alkoxylates, sorbilol esters, C8-C22 alkyl or alkenyl polyglycosides, polyalkoxy styrylaryl ethers, alkylamine oxides, block copolymer ethers, polyalkoxylated fatty glycende, polyalkylene glycol cthers, hncar aliphatic or aromatic polyesters, organo silicones, polyaryl phénols, sorbitol ester alkoxylates, polyalkylene oxide block copolymers, acrylic copolymers and mono- and diesters of ethylenc glycol and mixtures thercof.

Examples of anionic surfactants include alcohol sulfates, alcohol ether sulfates, alkylaryl cther sulfates, alkylaryl sulfonates such as alkylbenzene sulfonates and alkylnaphthalene sulfonates and salts thereof, alkyl sulfonates, mono- or di-phosphate esters of polyalkoxylated alkyl alcohols or alkylphenols , mono- or di-sulfosuccinatc esters of C12-C15 alkanols or polyalkoxylated C12-C15 alkanols, alcohol ether carboxylates, phenolic ether carboxylates, polybasic acid esters of ethoxylated polyoxyalkylene glycols consisting of oxybutylene or the residue of tetrahydrofuran. sulfoalkylamides and salts thereof such as N-mcthyl-Noleoyltaurate Na sait, polyoxyalkylene alkylphenol carboxylates, polyoxyalkylene alcohol carboxylates alkyl polyglycoside/alkcnyl succinic anhydride condensation products, alkyl ester sulfates, napthalene sulfonates, naphthalene formaldéhyde condensâtes, alkyl sulfonamides, sulfonated aliphatic polyesters, sulfate esters of styrylphenyl alkoxylates, and sulfonale esters of styrylphenyl alkoxylates and their corresponding sodium, potassium, calcium, magnésium, zinc, ammonium, alkylammonium. dicthanolammonium, or triethanolammonium salts, salts of ligninsulfonic acid such as the sodium, potassium, magnésium, calcium or ammonium sait, polyarylphenol polyalkoxycther sulfates and polyarylphenol polyalkoxyether phosphates, and sulfatcd alkyl phénol ethoxylates and phosphated alkyl phénol ethoxylates.

Cationic surfactants include alkanol amides of Cs-Cis fatty acids and Cs-Cis fatty amine polyalkoxylates, Cio-Cis alkyldimethylbenzylammonium chlorides, coconut alkyldimethylaminoacetic acids, and phosphate esters of Cs-Cis fatty amine polyalkoxylates.

Emulsifiers which can be advantageously employed herein can be rcadily determined by those skilled in the art and include various non-ionic, anionic, cationic and amphoteric emulsifiers, or a blend of two or more emulsifiers. Examples of nonionic emulsifiers useful in preparing the emulsifiable concentrâtes include the polyalkylene glycol ethers and condensation products of alkyl and aryl phénols, aliphatic alcohols, aliphatic amines or fatty acids with ethylenc oxide, propylene oxides such as the ethoxylated alkyl phénols and carboxylic esters solubilized with the polyol or polyoxyalkylene. Cationic emulsifiers include quatemary ammonium compounds and fatty amine salts. Anionic emulsifiers include the oil-soluble salts (e.g., calcium) of alkylaryl sulfonic acids, oil-soluble salis or sulfated polyglycol cthers and appropriatc salis of phosphatcd polyglycol cthcr.

In an embodiment, colorants include iron oxide, titanium oxide and Prussian Bluc, and organic dyestuffs, such as alizarin dyestuffs. azo dyestuffs or métal phthalocyaninc dyesluffs, and trace 5 cléments, such as salts of iron, manganèse, boron, copper, cobalt, molybdenum and zinc.

Another embodiment involves addition of a thickener or binder which may be selccted from bul not limitcd lo molasses, granulatcd sugar, alginatcs, karaya gum. jaguar gum, tragacanth gum, polysaccharide gum, mucilage, xanthan gum or combination thcrcof. In another embodiment. lhe binder may be selccted from silicates such as magnésium aluminium silicate, 10 polyvinyl acétates, polyvinyl acétate copolymcrs, polyvinyl alcohols, polyvinyl alcohol copolymers, celluloses, including cthylcelluloses and methylcelluloses, hydroxymethyl celluloses, hydroxypropylcelluloscs, hydroxymethylpropyl-cclluloscs, polyvinylpyrolidones, dextrins, malto-dextrins. polysaccharides, fats, oils, proteins, gum arabics, shellacs, vinylîdene chloride, vinylidene chloride copolymcrs, calcium lignosulfonates, acrylic copolymers, 15 starches, polyvinylacrylales, zeins, gclatin, carboxymcthylccllulose, chitosan, polycthylene oxide, acrylimide polymers and copolymcrs, polyhydroxycthyl acrylate, mcthylacrylimide monomers, alginate, cthylcellulose, polychloroprcnc and syrups or mixtures lhereof; polymers and copolymcrs of vinyl acétate, mcthyl cellulose, vinylidene chloride, acrylic, cellulose, polyvinylpyrrolidonc and polysaccharide; polymers and copolymers of vinylidene chloride and 20 vinyl acetate-ethylenc copolymcrs; combinations of polyvinyl alcohol and sucrose; plasticizers such as glyccrol, propylene glycol, polyglycols.

In another embodiment. antifreeze agcnl(s) added to the composition may be alcohols selected from the group comprising of but not limitcd to ethylcnc glycol, 1,2-propylene glycol, 1,3propylcne glycol, 1,2-butanediol, 1,3-butanediol, 1,4-bulancdiol, 1,4-pentancdiol, 3-methyl25 1.5-penlancdiol, 2,3-dimethyl-2,3-bulanediol, trimethylol propane, mannitol, sorbitol, glycerol, pentacrythritol. 1,4-cyclohcxanedimethanol, xylenol. bisphenols such as bisphcnol A or the like. In addition, cthcr alcohols such as dielhylcnc glycol, tricthylcnc glycol, tetraethylene glycol, polyoxycthylcnc or polyoxypropylcnc glycols of molecular wcighl up to about 4000, dielhylcnc glycol monomethylether, dielhylcnc glycol monoethylether, tricthylcnc 30 glycol monomethylether, butoxyelhanol, butylène glycol monobutylether, dipcntaerythritol, tripentaerythritol, tctrapcntacrythritol, diglycerol, triglycerol. tetraglycerol, pcnlaglyceroi, hexaglycerol. hcptaglyccrol, octaglyccroL

According to an embodiment. biocides include benzothiazoles, l,2-bcnzisothîazolin-3-one, sodium dichloro-s-triazinetrione, sodium benzoatc, potassium sorbatc. l,2-phenylisothiazolin-3-onc, inter chloroxylcnol paraoxybenzoatc butyl.

According to an embodiment. antifoam agents include polydimcthoxysiloxanc, polydimethylsiloxane, alkyl poly acrylatcs, castor oil, fatty acids, fatty acid esters, fatty acid sulfates, fatty alcohols, fatty alcohol esters, fatty alcohol sulfates, olive oil, mono and di glycerides, paraffin oil, paraffin wax, polypropylene glycol, silicone oil, vegctable and animal fats, sulfates of vegctable and animal fat. vegctable and animal oils, sulfates of vegctable and animal oils. vegctable and animal waxes. sulfates of vegctable and animal waxes , agents based on Silicon or magnésium stéarate, and combinations lhereof

Représentative organic liquids which can be employcd in preparing an emulsifiable concentratc include, for example, the aromatic liquids such as xylcnc, propyl benzene fractions, or mixed naphthalcnc fractions, minerai oils, substituted aromatic organic liquids such as dioctyl phthalate, kcroscnc, dialkyl amides of various fatty acids, particularly the dîmcthyl amides of fatty glycols and glycol dérivatives such as the n-butyl ether, ethyl ether or methyi ether of dicthylene glycol, and the methyi ether of triethylene glycol. Mixtures of two or more organic liquids arc also often suitably employcd in the préparation of an emulsifiable concentrate. The formulations can also contain other compatible additives, forcxample, plant growth regulators and other biologically active compounds used in agriculture.

The additives to be used for the formulation include, for cxample, a solid carrier such as kaolinite, sericitc, diatomaceous earth, slaked lime, calcium carbonate, talc, white carbon, kaoline, bentonitc, clay, sodium carbonate, sodium bicarbonate, mirabilitc, zeolite or starch; a solvent such as water, toluene. xylcnc, solvent naphtha, dioxane, dimethylsulfoxide, N,Ndimcthylformamide, dimethylacetamidc, N-methyl-2-pyrrolidone or an alcohol; an anionic surfactant such as a sait of fatty acid, a benzoate, a polycarboxylate, a sait of alkylsulfuric acid ester, an alkyl sulfate, an alkylaryl sulfate, an alkyl diglycol ether sulfate, a sait of alcohol sulfuric acid ester, an alkyl sulfonatc, an alkylaryl sulfonate, an aryl sulfonatc, a lignin sulfonate, an alkyldiphenylether disulfonate, a polystyrène sulfonate, a sait of alkylphosphoric acid ester, an alkylaryl phosphate, a styrylaryl phosphate, a sait of polyoxyethylene alkyl ether sulfuric acid ester, a polyoxyethylene alkylaryl ether sulfate, a sait of polyoxyethylene alkylaryl ether sulfuric acid ester, a polyoxyethylene alkyl ether phosphate, a sait of polyoxyethylene alkylaryl phosphoric acid ester, a sait of polyoxyethylene aryl ether phosphoric acid ester, a naphthalene sulfonic acid condcnscd with formaldéhyde or a sait of alkylnaphthalenc sulfonic acid condenscd with formaldéhyde; a nonionic surfactant such as a sorbitan fatty acid ester, a glycerin fatty acid ester, a fatty acid polyglyceridc, a fatty acid alcohol polyglycol ether, acetylene glycol, acetylene alcohol, an oxyalkylene block polymer, a polyoxyethylene alkyl ether, a polyoxyethylene alkylaryl ether, a polyoxyethylene styrylaryl ether, a polyoxyethylene glycol alkyl ether, polyethylcnc glycol, a polyoxyethylene fatty acid ester, a polyoxyethylene sorbitan fatty acid ester, a polyoxyethylene glycerin fatty acid ester, a polyoxyethylene hydrogenated castor oil or a polyoxypropylene fatty acid ester; and a vegetable oil or minerai oil such as olive oil, kapok oil, castor oil, palm oil, camcllia oil. coconut oil. sesame oil, corn oil, rice bran oil, peanut oil, cottonsced oil, soybean oil, rapeseed oil, linsecd oil, tung oil or liquid paraffins. These additives may suitably be selected for use alonc or in combination as a mixture of two or more of them. so long as the objccl of the présent disclosurc is met. Further, additives other than the above-mentioned may be suitably selected for use among those known in this fïeld. For cxample, various additives commoniy used. such as a fillcr, a thickcner, an anti-settling agent, an anti-freezing agent, a dispersion stabilizer, a safener, an anti-mold agent, a bubble agent, a disintegrator and a binder, may be used.

The agrochcmical formulation may also comprise one or more antioxidants. Preferably, the agrochemical formulation comprises an antioxidants. Antioxidants arc, for cxample. amino acids (e.g. glycine, histidine, tyrosine, tryptophan) and dérivatives thercof, imidazolc and imidazole dérivatives (e.g. urocanic acid), peptides, such as, for example, D.L-carnosine, Dcarnosinc, L-camosinc and dérivatives thcrcof (e.g. anscrine), carotenoids, carotènes (e.g. acarotene, β-carotcnc, lycopene) and dérivatives thereof, lipoic acid and dérivatives thereof (e.g. dihydrolipoic acid), aurothioglucose, propylthiouracil and further thio compounds (e.g. thioglyccrol, thiosorbitol, thioglycolic acid, thioredoxin, glutathione, cystcine, cystine, cystamine and the glycosyl, N-acctyl, mclhyl, ethyl, propyl, amyl, butyl, lauryl, palmitoyl, oleyl, γ-linoleyl, cholesteryl and glyceryl esters thercof), and salts thcrcof, dilauryl thiodipropionalc, distearyl thiodipropionate, thiodipropionic acid and dérivatives thereof (esters, ethers, peptides, lipids, nucléotides, nuclcosides and salts), and sulfoximinc compounds (e.g. buthionine sulfoximines, homocystéine sulfoximinc, buthionine sulfones, penta-, hexa-, heptathioninc sulfoximine) in very low tolcrated doses (e.g. pmol/kg to pmol/kg), also métal chelating agents (e.g. α-hydroxy fatty acids, EDTA, EGTA, phytic acid, lactoferrin), a-hydroxy acids (e.g. ci trie acid, lactic acid, malic acid), humic acids, bile acid, bile cxtracts, gallic esters (e.g. propyl, octyl and dodecyl gallatc), flavonoids, catechîns, bilirubin, biliverdin and dérivatives thereof, unsaturated fatty acids and dérivatives thereof (e.g. γ-linolenic acid, linoleic acid, arachidonic acid, oleic acid), folie acid and dérivatives thereof, hydroquinone and dérivatives thereof (e.g. arbutin), ubiquinone and ubiquinol, and dérivatives thereof, vitamin C and dérivatives thereof (e.g. ascorbyl palmitate, stéarate, dipalmitate, acetate, Mg ascorbyl phosphates, sodium and magnésium ascorbatc, disodium ascorbyl phosphate and sulfate, potassium ascorbyl tocopheryl phosphate, chitosan ascorbate), isoascorbic acid and dérivatives thereof, tocopherols and dérivatives thereof (e.g. tocopheryl acétate, linoleate, oleate and succinate, tocophereth-5, tocophereth-10, tocophereth-12, tocophereth-18, tocophereth-50, tocophersolan), vitamin A and dérivatives (e.g. vitamin A palmitate), the coniferyl benzoate of benzoin resin, rutin, rutinic acid and dérivatives thereof, disodium rutinyl disulfate, cinnamic acid and dérivatives thereof (e.g. ferulic acid, ethyl ferulate, caffeeic acid), kojic acid, chitosan glycolate and salicylate, butylhydroxytoluene, butylhydroxyanisol, nordihydroguaiacic acid, nordihydroguaiaretic acid, trihydroxybutyrophenone, uric acid and dérivatives thereof, mannose and dérivatives thereof, sélénium and sélénium dérivatives (e.g. selenomethionine), stilbenes and stilbene dérivatives (e.g. stilbene oxide, trans-stilbene oxide). According to the invention, suitable dérivatives (salts, esters, sugars, nucléotides, nucleosides, peptides and lipids) and mixtures of these specified active ingrédients or plant extracts (e.g. teatrec oil, rosemary extract and rosemarinic acid) which comprise these antioxidants can be used. In general, mixtures of the aforementions antioxidants are possible.

According to an embodiment, examples of solvents arc water, aromatic solvents (for example Solvesso products, xylene), paraffins (for example minerai oil fractions such as kerosene or diesel oil), coal tar oils and oils of vegctable or animal origin, aliphatic, cyclic and aromatic hydrocarbons, for example toluene, xylene, paraffm, tctrahydronaphthalcne, alkylated naphthalcnes or their dérivatives, alcohols (for example methanol. butanol, pcntanol, bcnzyl alcohol, cyclohexanol), ketones (for example cyclohexanone, gamma-butyrolactone), pyrrolidones (NMP, NEP, NOP), acétates (glycol diacetate), glycols, fatty acid dimethylamides, fatty acids and fatty acid esters, isophorone and dimcthylsulfoxide. In principle, solvent mixtures may also be used.

According to an embodiment, exemplary surfactants are alkali métal, alkalinc earth métal and ammonium salts of lignosulfonic acid, naphthalenesulfonates, phenolsulfonic acid, dibutylnaphthalcnesulfonic acid, alkylarylsulfonatcs, alkyl sulfates, alkylsulfonates, fatty alcohol sulfates, fatty acids and sulfated fatty alcohol glycol ethers, furthermore condensâtes of sulfonated naphthalene and naphthalene dérivatives with formaldéhyde, condensâtes of naphthalene or of naphthalenesulfonic acid with phénol and formaldéhyde, polyoxyethylene octylphenol ethers, ethoxylated isooctylphenol, octylphcnol, nonylphcnol, alkylphcnol polyglycol ethers, tributylphcnyl polyglycol ethers, tristcarylphenyl polyglycol ethers, alkylaryl polyether alcohols, alcohol and fatty alcohol/cthylcne oxide condensâtes, ethoxylated castor oil, polyoxyethylene alkyl ethers, ethoxylated polyoxypropylene, lauryl alcohol polyglycol ether acetal, sorbitol esters, lignosulfite wastc liquors and methylcellulose.

According to an embodiment, examples of carriers are minerai carths such as silica gels, silicates, talc, kaolin, attaclay, attapulgite, limestone, lime, chalk, bolc, loess, clay, dolomite, dialomaceous earth, calcium sulfate, magnésium sulfate, magnésium oxide, ground synthctic matcrials, fertilizers, such as, for cxample, ammonium sulfate, ammonium phosphate, ammonium nitrate, ureas, and products of vcgctable origin, such as ccrcal mcal. tree bark mcal, wood mcal and nutshcll mcal, cellulose powders, polyvinylpyrrolidone and other solid carriers.).

Excmplary preservatives arc for cxample l,2-benzisothiazolin-3-onc and/or 2-Mcthyl-2Hisothiazol-3-one or sodium benzoate or benzoie acid.

In an embodiment, the composition may bc in any agriculluraily suitable form for storage and application to the ground. The compositions may be produced by mixing the actives in the composition with an inert carrier, and adding surfactants and other adjuvants and carriers as needed and formulated into solid. or liquid formulations, including but not limited to wcttablc powders, granules, dusts, soluble (liquid) concentrâtes, suspension concentrâtes, oil in water émulsion, water in oil émulsion, emulsifiable concentrâtes, capsule suspensions, ZC formulations, oil dispersions or other known formulation types. The composition may also be used for treatment of a plant propagation material such as sceds etc.

In an embodiment, the method for controlling target weeds comprises

i. preparing a premix or tank-mix of the glufosinatc and the at least one herbicide; and ii. applying the prepared premix or tank-mix at the desired locus.

The compositions of the présent disclosure maybe applied simultancously as a tank mix or a formulation or may bc applied scqucntially. The application may bc made to the soil bcforc émergence of the plants, either prc-planting or post-planting. The application may bc made to lhe soil after emergence of the plants. The application may bc made as a foliar spray at different timings during crop development, with either one or more applications early or late post emergence. Herbicidal compositions according to the invention can also be incorporated into the soîl beforc, during or after sowing seeds of a crop. Thcse combinations as described above may bc applicd to the locus of the weeds, in an herbicidally effective amount.

In an embodiment. the method comprises applying composition containing glufosinate and at least onc herbicide as a tank mix.

In an embodiment. the method comprises applying composition containing glufosinate and the at least one herbicide as a premix.

In an embodiment. the method comprises applying in immédiate succession the glufosinate and at least onc herbicide.

The compositions of the présent disclosure may bc applicd in any known ways or conventional methods known to a person skilled in art. Non-limiting examples of such methods are foliar spray, basal barking, stem injection, drill and fill method, axe eut method, cul stump, eut and swab, stem scrapcr, wick application and so forth. The compositions of the présent disclosure arc used in the customary manner, for example by watering. spraying, alomizing, dusting or scattering. Said compositions can bc applicd to a locus by the use of conventional ground sprayers, granule applicators, watering (drcnching), drip irrigation, spraying, atomizing, broadeasting, dusting, foaming, spreading-on, aerial methods of spraying, aerial methods of application, methods utilizing application using modem technologies such as. but not limited to, drones, robots and by other conventional mcans known to thosc skilled in the art.

In an embodiment, the présent invention provides a method of increasing yicld in a crop by application of a syncrgistic herbicidal combination as described herein.

In an embodiment. the présent invention provides a method of improving the plant hcalth by application of a syncrgistic herbicidal combination as described herein.

The herbicidal combinations/compositions of the présent invention are highly safe to crop plants and capable of controlling target weeds problematic in e.g. paddy ficlds, upland fields or non-agricultural fields over a widc range of from pre-cmergency to post-emcrgcncc.

The présent disclosure is more particularly described in the following examples that are intended as illustration only, sincc numerous modifications and variations within the scope of the présent disclosurc will be apparent to (hose of skiil in the art. Unlcss otherwisc noted, ail parts, percentages, and ratios reported in the following cxamples are on a weight basis, and ail rcagents used in the examples werc obtained or are availabié from the Chemical suppliers.

The following cxamples illustrâtes the composition, underlying effect and basic methodology of the présent disclosurc.

Examples:

The following cxamples demonstratc the présent disclosurc.

Composition:

Following active ingrédient compounds were used in the présent disclosurc to prépare combinations/compositions of L-glufosinate with other herbicides.

Active ingrédient	Dose a.i., g/L
L-glufosinate	280
Oxyfluorfen	240
Imazethapyr	106
Carfentrazone	400
Glyphosatc	648
Flumioxazin	500
2,4-D	670
Triclopyr	480
Clethodim	240
Haloxyfop	124.7

Evaluation of Post-emergence Herbicidal Activity of composition under Field Conditions

Methodology: Grccnhouse trials werc carried out to evaluate the efficacy of the combination of L-glufosinate and the other herbicides on weedy Glycine max. The soil used was sandy clay loam - Sand: 68,0%; Silt: 8,0%; Clay: 24,0%. Ail treatments were in 3 réplications per treatment with a spray volume of 150 L/h.

Evaluation

The cxpccted efficacy of a combination of L-glufosinatc and the other herbicides was calculated using the well-cstablishcd Colby method. Any différence between the observed and “expected” efficacy could be attributed to synergy between the two compounds.

In the Colby method, the expccted (or predicted) response of a combination of herbicides is calculated by taking the product of the observed response for each îndividual component of the combination when applied alonc, divided by 100, and subtracting this value from the sum of the observed response for each component when applied alone. An unexpectcd enhancement in efficacy of the combination is then determined by comparing the observed response of the combination to the cxpccted (or predicted) response as calculated from the observed response of each îndividual component alonc. If the observed response of the combination is greater than the expected (or predicted) response, or stated conversely, if the différence between the observed and expccted response is greater than zéro, then the combination is said to be synergistic or unexpcctcdly effective (Colby,S. R., Weeds. 1967(15), p. 20-22). The Colby method requires only a single dose of each herbicide applied alone and the mixture of both doses. The formula used to calculate the expccted efficacy (EE) which was compared with the observed efficacy (OE) to détermine the efficacy of the présent disclosure is explaincd hcreinbelow:

The cxpccted efficacy for a combination of two active ingrédients is as follows:

EE = (A + B - (A x B)/100)

The cxpccted efficacy for a combination of thrcc active ingrédients is as follows:

EE = A + B + C - (AB + AC + BC)/100 + ABC/10,000 Whcrc.

A = Observed efficacy of active ingrédient A at the same concentration as used in the mixture. B = Observed efficacy of the active ingrédient B at the same concentration as used in the mixture.

C - Observed efficacy of the active ingrédient C at the same concentration as used in the mixture.

Table l: Table l demonstrates synergy on weeds using the combination of L-glufosinate and other herbicides. The percentage efficacy was calculatcd after 14, 21, 28, 35 days of applications (DAA). The target weed was weedy Glycine max, and the concentration of the herbicide and the rcsults are recorded in the table 1 below:

Active ingrédient, dose a.i., g/h	14 DAA	21 DAA	28 DAA	35 DAA
Control%	Colby*	Control %	Colby*	Control %	Colby*	Control%	Colby*
L-glufosinate, 150	60	-	63.3	-	63.3	-	52.7	-
Oxyfluorfen, 107.1	46.7	-	45.0	-	43.3	-	35.0	-
Imazethapyr, 75.0	10	-	20.0	-	20.0	-	15.0	-
Carfentrazone. 7,5	50.3	-	44.3	-	44.3	-	39.3	-
Carfentrazone, 9.0	51.7		51.0	-	51.0	-	46.7	-
L-glufosinate, 150 + oxyfluorfen 107.1	87.7	78.7	86.3	79.8		79.2	81.0	69.3
L-glufosinate, 150 + imazethapyr, 75		64.0		70.6	IIIIM·	70.6	fijlili	59.8
L-glufosinate, 150 + carfentrazone, 7.5	89,3	80.1	90Ό	79.6	lllfllll	79.6	lililliii	71.3
L-glufosinate, 150 + carfentrazone. 9		80.7	91.7	82.0		82.0		74.8
L-glufosinate, 150 + imazethapyr, 75 + carfentrazone, 7.5		82.1		83.6		83.6	96,0	75.6

*Expected control according to Colby ’s Formula

Table 2: Table 2 demonstrates synergy on weeds using the combination of L-glufosinate and glyphosate. The percentage efficacy was calculated after 3, 7, 14, 21, 28, 35 days of application 10 (DAA). The target weed was weedy Glycine max, and the concentration of the herbicide and the results are recorded in the table 2 below:

Active ingrédient, g ai/h

3 DAA

7 DAA

14 DAA

21 DAA

28 DAA

35 DAA

% contro 1

Colb y value

% contro 1

Colb y value

% contro 1

Colb y value

% contro 1

Colb y value

% contro 1

Colb y value

% contro 1

Colb y value

Lglufosinate , 150

15

53.3

71

66.7

56.7

41.7

Glyphosat e, 379	0	-	0	-	0	-	0	-	0	-	0	-
Lglufosinate , 150 + Glyphosat e, 379	29.3	15	76	53.3	90	71	93	66.7	93	56.7	90.7	41.7

*Expected control according to Colby ’s Formula

Table 3: Table 3 demonstrates synergy on weeds using the combination of L-glufosinate and 5 flumioxazin. The pcrccntage effïcacy was calculatcd after 3, 7, 21, 28, 35 days of application (DAA). The target weed was weedy Glycine max, and the concentration of the herbicide and the results are recorded in the table 3 below:

Active ingrédient, g ai/h	3 DAA	7 DAA	21 DAA	28 DAA	35 DAA
% control	Colby value	% control	Colby value	% control	Colby value	% control	Colby value	% control	Colby value
L-glufosinate, 150	15	-	53.3	-	66.7	-	56.7	-	41.7	-
Flumioxazin, 30	7.7		31.7	-	40	-	40	-	30	-
L-glufosinate, 150 + Flumioxazin, 30	eg||	21.5		68.1	833	80	81,7	74	767	59.2

Table 4: Table 4 demonstratcs synergy on wccds using lhe combination of Lglufosinate and 2,4-D. The pcrcentage efficacy was calculated aftcr 7, 14, 21, 28, 35 days of application (DAA). The target wccd was weedy Glycine max, and the concentration of the herbicide and the results arc rccordcd in the table 4 below:

Active ingrédient, g ai/h	7 DAA	14 DAA	21 DAA	28 DAA	35 DAA
% contre 1	Colb y value	% contre 1	Colb y value	% contre 1	Colb y value	% contre l	Colb y value	% contre 1	Colb y value
Lglufosinatc , 150	53.3		71		66.7		56.7		41.7
2.4-D, 204	41.7	-	42.7	-	50.7	-	53.3	-	48.3	-
Lglufosinate , 150 + 2,4d, 204	77	72.8	m	83.4	93.3	83.6		79.8	84.3	69.9

Table 5: Table 5 demonstratcs synergy on weeds using the combination of Lglufosinatc and triclopyr. The pcrcentage efficacy was calculated aftcr 7 and 14 days of application (DAA). The target weed was weedy Glycine max, and lhe concentration of the herbicide and lhe results arc rccorded in the table 5 below:

Active ingrédient, g ai/h	7 DAA	14 DAA
	% control	Colby value	% control	Colby value
L-glufosinate, 150	53.3	-	71	-
Triclopyr, 288	50	-	79.3	-
L-glufosinate, 150 + triclopyr, 288	82.7	76.7	983	94

Table 6: Table 6 demonstratcs synergy on wccds using the combination of Lglufosinatc and clethodim. The pcrcentage efficacy was calculated aftcr 3, 7, 14, 21, 28, 35 days of application (DAA). The target wccd was weedy Glycine max, and lhe concentration of lhe herbicide and the results are recordcd in the table 6 below;

Active ingredie nt. g ai/h	3 DAA	7 DAA	14 DAA	21 DAA	28 DAA	35 DAA
% contr ol	Col by valu e	% contr ol	Col by valu e	% contr ol	Col fey valu e	% contr ol	Col by valu e	% contr ol	Col by valu e	% contr ol	Col by valu e
Lglufosin ate. 150	15		53.3		71		66.7		56.7		41.7
Clethodi m. 45	0	-	0	-	0	-	0	-	0	-	0	-
Lglufosin ate, 150 + clethodi m, 45	30		15		53.3	Oïii	71	88	66.7		56.7	«2.7	41.7

Table 7: Table 7 demonstrates synergy on weeds using the combination of Lglufosinate and haloxyfop. The percentage efficacy was calculated after 3, 7, 14, 5 21, 28, 35 days of application (DAA). The targel weed was weedy Glycine max, and the concentration of the herbicide and the results are recorded in the table 7 below:

Active ingredie □L g ai/h	3 DAA	7 DAA	14 DAA	21 DAA	28 DAA	35 DAA
% contr ol	Col by valu e	% contr ol	Col by valu e	% contr ol	Col by valu e	% contr ol	Col by valu e	% contr ol	Col by valu e	% contr ol	Col by valu e
L- glufosin ate, 150	15		53.3		71		66.7		56.7		41.7
Haloxyf op, 50	5	-	13.3	-	15	-	12.3	-	12.3	-	12.3
Lglufosin ate, 150 +	3m,v;	19.3		59.5	51	75.4	92.3	70.8	90	62	4M,	48.9

haloxyfo p, 50

The rcsults in tables l and 2-7 clearly demonstrate synergy between L-glufosinate and the other herbicides. The large différence between the observed and the expectcd cfficacy clearly demonstrates the syncrgistic effcct of the combination.

Whilc (hc foregoing written description of the invention enablcs one of ordinary skîll to makc and use what is considered presenlly to be the best mode thereof, those of ordinary skill will understand and apprcciatc the existence of variations, 10 combinations, and équivalents of the spécifie embodiment, method, and examples herein. The invention should, therefore, not be lîmitcd by the above describcd embodiment, method, and examples, but by ail embodiments and methods within the scope and spirit of the invention.

Claims (21)

1. l. A method comprising controlling growth of undesirablc végétation at a locus by treating the locus with a synergistic combination comprising glufosinate and at least one herbicide selected from:

   (a) nitrophenyl ether class herbicides;

   (b) imidazolinone class herbicides;

   (c) organophosphorous class herbicides;

   (d) dicarboximide class herbicides;

   (e) phenoxyacetic class herbicides;

   (f) pyridine class herbicides;

   (g) cyclohexene oxime class herbicides;

   (h) aryloxyphcnoxypropionic class herbicides;

   (i) triazolone class herbicides, (j) uracil class herbicides, and combinations thereof, wherein the undesirable végétation is weedy Glycine max.
2. 2. The method as claimed in claim 1, wherein the glufosinate is L-glufosinate.
3. 3. The method as claimed in claim 1, wherein:

   (a) the nitrophenyl ether class herbicide is selected from the group consisting of oxyfluorfen, acifluorfen, aclonifen, bifenox, chlomethoxyfen, chlornitrofen, etnipromid, fluorodifen, fluoroglycofen, fluoronitrofen, fomesafen, fucaomi, furyloxyfen, halosafen. lactofen, nitrofen, nitrofluorfen, and combinations thereof;

   (b) the imidazolinone class herbicide is selected from the group consisting of imazethapyr, imazamethabenz, imazamox, imazapic, imazapyr, imazaquin, and combinations thereof;

   (c) the organophosphorous class herbicide is selected from the group consisting of glyphosatc, amiprofos-mcthyl, amiprophos, anilofos, bensulide, bilanafos, butamifos, elaeyfos, 2,4-DEP, DMPA ((0-(2,4dichlorophenyl) O-mcthyl isopropylphosphoramidothioate)), EBEP (cthyl bis(2-ethylhexyl)phosphinatc), fosaminc, glufosinate-P, piperophos, and combinations thercof;

   (d) the dicarboximidc class herbicide is selected from the group consisting of cinidon-ethyl, flumezin, flumiclorac, flumioxazin, flumipropyn, and combinations thercof;

   (e) the phenoxyacctic class herbicide is selected from the group consisting of elaeyfos, 4-CPA (p-Chlorophenoxyacctic acid), 2,4-D, 3,4DA, MCPA (2-mcthyl-4-chlorophenoxyacetic acid), MCPA-thioethyl, 2,4,5-T and combinations thercof;

   (f) the pyridine class herbicide is selected from the group consisting of aminopyralid, cliodinate. clopyralid, diflufcnican, dithiopyr, florpyrauxifen, flufcnican, fluroxypyr, halauxifen, haloxydine, picloram, picolinafen, pyriclor, pyroxsulam, thîazopyr, triclopyr, xyloxadine, and combinations thercof;

   (g) the cyclohcxcnc oxime class herbicide is selected from the group consisting of alloxydim, butroxydim, clcthodim, cloproxydim, cycloxydim, profoxydim, sethoxydim, tepraloxydim, tralkoxydim, and combinations thercof;

   (h) the aryloxyphenoxypropionic class herbicide is sclcctcd from the group consisting of chlorazifop, clodinafop, clofop, cyhalofop, diclofop, fenoxaprop, fenoxaprop-P, fenthiaprop, fluazifop, fluazifop-P, haloxyfop, haloxyfop-P, isoxapyrifop, metamifop, propaquizafop, quizalofop, quizalofop-P, trifop, and combinations thereof;

   (i) the triazolone class herbicide is selected from the group consisting of amicarbazonc, bcncarbazonc, carfcntrazone, flucarbazone, ipfencarbazone, propoxycarbazone, sulfentrazonc, thiencarbazone and combinations thereof; and/or (j) the uracil class herbicide is sclcctcd from the group consisting of bromacil, isocil, lenacil, tcrbacil, benzfendizone, butafenacil, cpyrifcnacil, flupropacil, sanufcnacil, liafenacil, and combinations thereof.
4. 4. The method as claimcd in claim 3. whcrein:

   (a) the nitrophcnyi cthcr class herbicide is oxyfluorfen;

   (b) the imidazolinonc class herbicide is imazethapyr;

   (c) the organophosphorous class herbicide is glyphosatc;

   (d) the dicarboximide class herbicide is flumioxazin;

   (c) the phenoxyacctic class herbicide is 2,4-D;

   (f) the pyridinc class herbicide is triclopyr; i (g) the cyclohexenc oxime class herbicide is clethodim;

   (h) the aryloxyphcnoxypropionic class herbicide is haloxyfop;

   (i) the triazolone class herbicide is carfcntrazonc; and/or । (j) the uracil class herbicide is saflufenacil.
5. 5. The method as claimcd in claim l, whcrein the weight ratio of glufosinate and the at least onc herbicide is l : 100 to 100:1.
6. 6. The method as claimcd in claim 5, whcrein lhe weight ratio of glufosinate and the at least onc herbicide is 1:75 to 75:1.

   i I
7. 7. The method as claimcd in daims 1, whcrein glufosinate is présent in an amount in the range of 100 to 400 g ai/L, preferably 180 to 380 g ai/L.
8. 8. The method as claimcd in daims 1, whcrein at least one herbicide sclcctcd from (a) the nitrophenyl cthcr class herbicide is présent in an amount in the range of 100 to 400 g ai/L, preferably 140 to 340 g ai/L;

   (b) the imidazolinone class herbicide is présent in an amount in the range of 10 to 250 g ai/L, preferably 50 - 200 g aî/L;

   (c) the organophosphorous class herbicide is présent in an amount in the range of 200 to 1000 g ai/L, preferably 400 to 800 g aî/L;

   (d) the dicarboximide class herbicide is présent in an amount in the range of 200 - 800 g ai/L, preferably 300 to 700 g ai/L;

   (c) the phenoxyacctic class herbicide is présent in an amount in the range of 400 to 1200 g ai/L, preferably 600 - 1000 g ai/L;

   (f) the pyridine class herbicide is présent in an amount in the range of 300 - 1000 g ai/L. preferably 400 to 900 g ai/L;

   (g) the cyclohexcne oxime class herbicide is présent in an amount in the range of 100 - 400 g ai/L, preferably 150 to 350 g ai/L;

   (h) the aryloxyphcnoxypropionic class herbicide is présent in an amount in the range of l to 250 g ai/L, preferably 10 - 200 g ai/L;

   (i) the triazolone class herbicide is présent in an amount in the range of 100 - 800 g ai/L, preferably 200 to 600 g ai/L; and/or (j) the uracil class herbicide is présent in an amount in the range of 1 1000 g ai/L, preferably 50 to 800 g ai/L.
9. 9. The method as claimed in claîms 1, whercin glufosinate is applicd at an application rate of 50 - 350 g ai/h, preferably 100 g ai/h to 250 g ai/h.
10. 10. The method as claimed in daims 1, wherein atleast one herbicide selected from (a) the nitrophcnyl ether class herbicide is applicd at an application rate of 5-250 g ai/h. preferably at a rate of 50-150 g ai/h;

    (b) the imidazolinone class herbicide is applicd at an application rate of 5200 g ai/h, preferably at a rate of 20 to 150 g ai/h;

    (c) the organophosphorous class herbicide is applied at an application rate of 100-800 g ai/h. preferably at a rate of 200 - 500 g ai/h;

    (d) the dicarboximide class herbicide is applicd at an application rate of l to 200 g ai/h, preferably 5-100 g ai/h;

    (e) the phenoxyacetic class herbicide is applied at an application rate of 50 - 400 g ai/h, preferably 100 - 300 g ai/h;

    (f) the pyridine class herbicide is applicd at an application rate of 50-500 g ai/h, preferably at a rate of 100-400 g ai/h;

    (g) the cyclohexene oxime class herbicide is applied at an application rate of 1-150 g ai/h, preferably at a rate of 10 - 100 g ai/h;

    (h) the aryloxyphenoxypropionic class herbicide is applied at an application rate of 1 -150 g ai/h, preferably at a rate of 10 - 100g ai/h;

    (i) the triazolone class herbicide is applied at an application rate of 0.5-100 g ai/h, preferably at a rate of 1 - 50 g ai/h; and/or (j) the uracil class herbicide is applicd at an application rate of 10-150 g ai/h, preferably at a rate of 20 - 70 g ai/h.
11. 11. The method as claimed in claîm 1, wherein the syncrgistic combination comprises glufosinate; an imidazolinone class herbicide, and a triazolone class herbicids.
12. 12. The method as claimed in claim 11, wherein the imidazolinone class herbicide is imazethapyr, and wherein triazolone class herbicide is carfentrazone.
13. 13. The method as claimed in claim 11, wherein the imidazolinone class herbicides, and the triazolone class herbicide arc présent in a ratio of 1:100 to 100:1, more preferably 1:10 to 10:1.
14. 14. The method as claimed in claim 1, wherein the method comprises i. preparing a premix or a tank-mix of the glufosinate and the al least one herbicide; and ii. applying the prepared premix or tank-mix at the locus.
15. 15. The method as elaimed in claim 1, whercin the method comprises applying in immédiate succession the glufosinate and the at least onc herbicide.
16. 16. A synergistic composition for controlling weedy Glycine max comprising glufosinate and at least one herbicide selected from:

    (a) nitrophenyl ether class herbicides;

    (b) imidazolinone class herbicides;

    (c) organophosphorous class herbicides;

    (d) dicarboximide class herbicides;

    (c) phenoxyacctic class herbicides;

    (f) pyridine class herbicides;

    (g) cyclohexene oxime class herbicides;

    (h) aryloxyphenoxypropionic class herbicides;

    (i) triazolone class herbicides;

    (j) uracil class herbicides, and combinations thcrcof.
17. 17. The synergistic composition as elaimed in claim 16, wherein the glufosinate is L-glufosinate.
18. 18. The synergistic composition as elaimed in claim 16, whercin the composition further comprises at least one agrochemîcally suitablc excipient.
19. 19. The synergistic composition as elaimed in claim 16, whercin:

    (a) the nitrophcnyl ether class herbicide is selected from the group consisting of oxyfluorfen, acifluorfcn, aclonifen, bifenox, chlomcthoxyfen, chlornitrofen. etnipromid. fluorodifen, fluoroglycofen, fluoronitrofen, fomcsafen. fucaomi, furyloxyfen, halosafen, lactofen, nitrofcn, nitrofluorfen, and combinations thereof;

    (b) the imidazolinone class herbicide is selected from the group consisting of imazelhapyr, imazamethabenz. imazamox, imazapic, imazapyr, imazaquin, and combinations thereof;

    (c) the organophosphorous class herbicide is selected from the group consisting of glyphosatc, amiprofos-methyl, amiprophos, anilofos, bensulide. bilanafos, butamifos, elaeyfos, 2,4-DEP, DMPA ((0-(2,4dichlorophenyl) O-mcthyl isopropylphosphoramidothioate)), EBEP (ethyl bis(2-ethylhexyl)phosphinatc), fosaminc, glufosinate-P, piperophos. and combinations thereof;

    (d) the dicarboximide class herbicide is selected from the group consisting of cinidon-cthyl, flumezin, flumiclorac, flumioxazîn, flumipropyn. and combinations thereof;

    (e) the phenoxyacetic class herbicide is selected from the group consisting of elaeyfos, 4-CPA (p-Chlorophenoxyacetic acid), 2,4-D, 3,4DA, MCPA (2-mcthyl-4-chlorophenoxyacetic acid), MCPA-thiocthyl, 2,4,5-T and combinations thereof;

    (f) the pyridinc class herbicide is selected from the group consisting of aminopyralid, cliodinate, clopyralid, diflufcnican, dithiopyr, florpyrauxifen, flufenican, fluroxypyr, halauxifen, haloxydine, picloram. picolinafen, pyriclor, pyroxsulam, thiazopyr, triclopyr, xyloxadine, and combinations thereof;

    (g) the cyclohexcnc oxime class herbicide is selected from the group consisting of alloxydim, butroxydim, clelhodim, cloproxydim, cycloxydim, profoxydim. sethoxydim, tepraloxydim, tralkoxydim, and combinations thereof;

    (h) the aryloxyphcnoxypropionic class herbicide is selected from lhe group consisting of chlorazifop, clodinafop, clofop, cyhalofop, diclofop, fenoxaprop, fenoxaprop-P, fenthiaprop, fluazifop, fluazifop-P. haloxyfop.

    haloxyfop-P, isoxapyrifop, metamifop, propaquizafop, quizalofop, quizalofop-P, trifop, and combinations thereof;

    (i) the triazolonc class herbicide is selected from the group consisting of amicarbazonc, bcncarbazonc, carfentrazone, flucarbazone, ipfcncarbazonc, propoxycarbazone, sulfentrazone, thiencarbazone and combinations thereof; and/or (j) the uracil class herbicide is selected from the group consisting of bromacil, isocil, lenacil, terbaeil, benzfendizone, butafenacîl, epyrifenacil, flupropacil, saflufenacil, tiafenacîl. and combinations thereof.
20. 20. The composition as elaimed in claim 16, wherein the weight ratio of glufosinate. and the at least one herbicide is l : 100 to 100:1.
21. 21. A synergistic composition for controlling weedy Glycine max comprising glufosinate; a herbicide selected from imidazolinone class of herbicides and a herbicide selected from triazolonc class of herbicides.