PE104499A1 - Composicion farmaceutica de tiazolidindiona e insulina para el tratamiento de la diabetes - Google Patents

Composicion farmaceutica de tiazolidindiona e insulina para el tratamiento de la diabetes

Info

Publication number: PE104499A1
Authority: PE; Peru
Prior art keywords: insulin; diabetes; treatment; tiazolidindiona; pharmaceutical composition
Prior art date: 1997-06-18

Application number

PE1998000535A

Other languages

English (en)

Spanish (es)

Inventor

Stephen Alistair Smith

Original Assignee

Smithkline Beecham Plc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-06-18

Filing date

1998-06-18

Publication date

2000-01-13

1998-06-18 Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc

2000-01-13 Publication of PE104499A1 publication Critical patent/PE104499A1/es

Links

NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 title abstract 6
102000004877 Insulin Human genes 0.000 title abstract 3
108090001061 Insulin Proteins 0.000 title abstract 3
206010012601 diabetes mellitus Diseases 0.000 title abstract 3
229940125396 insulin Drugs 0.000 title abstract 3
239000008194 pharmaceutical composition Substances 0.000 title 1
-1 AMINO Chemical class 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin

Landscapes

Health & Medical Sciences (AREA)
Diabetes (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Endocrinology (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Epidemiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Gastroenterology & Hepatology (AREA)
Hematology (AREA)
Obesity (AREA)
Emergency Medicine (AREA)
Zoology (AREA)
Immunology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Peptides Or Proteins (AREA)
Plural Heterocyclic Compounds (AREA)

PE1998000535A 1997-06-18 1998-06-18 Composicion farmaceutica de tiazolidindiona e insulina para el tratamiento de la diabetes PE104499A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GBGB9712866.4A GB9712866D0 (en)	1997-06-18	1997-06-18	Novel method of treatment

Publications (1)

Publication Number	Publication Date
PE104499A1 true PE104499A1 (es)	2000-01-13

Family

ID=10814527

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PE1998000535A PE104499A1 (es)	1997-06-18	1998-06-18	Composicion farmaceutica de tiazolidindiona e insulina para el tratamiento de la diabetes

Country Status (30)

Country	Link
EP (1)	EP0999837A1 (da)
JP (1)	JP2002504138A (da)
KR (1)	KR20010013843A (da)
CN (1)	CN1133431C (da)
AP (1)	AP1287A (da)
AR (2)	AR012997A1 (da)
AU (1)	AU8216398A (da)
BG (1)	BG104059A (da)
BR (1)	BR9810444A (da)
CA (1)	CA2294141A1 (da)
CO (1)	CO4940454A1 (da)
DZ (1)	DZ2521A1 (da)
EA (1)	EA004800B1 (da)
GB (1)	GB9712866D0 (da)
HU (1)	HUP0003260A3 (da)
ID (1)	ID23951A (da)
IL (1)	IL133143A0 (da)
IN (1)	IN189723B (da)
MA (1)	MA26511A1 (da)
NO (1)	NO996265L (da)
OA (1)	OA11517A (da)
PE (1)	PE104499A1 (da)
PL (1)	PL343123A1 (da)
SK (1)	SK179399A3 (da)
TR (1)	TR199903095T2 (da)
TW (1)	TW587937B (da)
UA (1)	UA70299C2 (da)
UY (1)	UY25050A1 (da)
WO (1)	WO1998057636A1 (da)
ZA (1)	ZA985237B (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6291495B1 (en) *	1997-02-24	2001-09-18	Robert B. Rieveley	Method and composition for the treatment of diabetes
US7045519B2 (en)	1998-06-19	2006-05-16	Chiron Corporation	Inhibitors of glycogen synthase kinase 3
TWI249401B (en)	1999-04-14	2006-02-21	Takeda Chemical Industries Ltd	Agent for improving ketosis
AU765498B2 (en)	1999-04-23	2003-09-18	Smithkline Beecham Plc	Novel pharmaceutical
US6660716B1 (en) *	1999-06-21	2003-12-09	Eli Lilly And Company	Method for treating non-insulin dependent diabetes using thiazolidinediones with glucagon-like peptide-1 and agonists thereof
CA2369839A1 (en) *	1999-06-25	2001-01-04	Minimed, Inc.	Compositions of insulin and insulin-related peptide for treating diabetes
US6468507B1 (en) *	2000-05-01	2002-10-22	Aeropharm Technology, Inc.	Non-aqueous aerosol formulation comprising rosiglitazone maleate, a non-aqueous carrier, and an amino acid stabilizer
GB0023970D0 (en) *	2000-09-29	2000-11-15	Smithkline Beecham Plc	Novel pharmaceutical
AU2002248464A1 (en)	2001-02-21	2002-09-12	Medtronic Minimed, Inc.	Stabilized insulin formulations
US6531461B1 (en)	2001-06-04	2003-03-11	Louis Obyo Obyo Nelson	Medicament for the treatment of diabetes
WO2002100396A1 (en) *	2001-06-07	2002-12-19	Wyeth	COMBINATION OF A PTPase INHIBITOR AND A THIAZOLIDINEDIONE AGENT
US6737401B2 (en)	2001-06-28	2004-05-18	Metronic Minimed, Inc.	Methods of evaluating protein formulation stability and surfactant-stabilized insulin formulations derived therefrom
ES2295692T3 (es) *	2002-11-08	2008-04-16	F. Hoffmann-La Roche Ag	Nuevos derivados de 4-alcoxioxazol sustituido como agonistas de ppar.
US7264813B2 (en)	2003-09-24	2007-09-04	Nikken Sohonsha Corporation	Therapeutic uses of Dunaliella powder
CN102389427A (zh) *	2011-10-10	2012-03-28	成都恒瑞制药有限公司	含有罗格列酮和盐酸西替利嗪的固体口服制剂

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK0719140T3 (da) *	1993-09-15	2008-03-03	Daiichi Sankyo Co Ltd	Anvendelse af thiazolidindioner til forebyggelse eller forsinkelse af indtræden af NIDDM
CN1192683A (zh) *	1995-08-10	1998-09-09	沃尼尔·朗伯公司	减少非胰岛素依赖型糖尿病患者外源性胰岛素给药量的方法
DK0859608T3 (da) *	1995-09-18	2004-06-14	Ligand Pharm Inc	Behandling af NIDDM med RXR-agonister

1997
- 1997-06-18 GB GBGB9712866.4A patent/GB9712866D0/en active Pending
1998
- 1998-06-15 UA UA99126881A patent/UA70299C2/uk unknown
- 1998-06-15 HU HU0003260A patent/HUP0003260A3/hu unknown
- 1998-06-15 CN CNB988062232A patent/CN1133431C/zh not_active Expired - Fee Related
- 1998-06-15 AP APAP/P/1999/001718A patent/AP1287A/en active
- 1998-06-15 EP EP98932169A patent/EP0999837A1/en not_active Withdrawn
- 1998-06-15 TR TR1999/03095T patent/TR199903095T2/xx unknown
- 1998-06-15 JP JP50375799A patent/JP2002504138A/ja not_active Ceased
- 1998-06-15 SK SK1793-99A patent/SK179399A3/sk unknown
- 1998-06-15 PL PL98343123A patent/PL343123A1/xx unknown
- 1998-06-15 ID IDW991627A patent/ID23951A/id unknown
- 1998-06-15 IL IL13314398A patent/IL133143A0/xx unknown
- 1998-06-15 AU AU82163/98A patent/AU8216398A/en not_active Abandoned
- 1998-06-15 KR KR1019997011864A patent/KR20010013843A/ko not_active Ceased
- 1998-06-15 CA CA002294141A patent/CA2294141A1/en not_active Abandoned
- 1998-06-15 EA EA200000042A patent/EA004800B1/ru not_active IP Right Cessation
- 1998-06-15 WO PCT/EP1998/003692 patent/WO1998057636A1/en not_active Ceased
- 1998-06-15 BR BR9810444-6A patent/BR9810444A/pt not_active IP Right Cessation
- 1998-06-17 AR ARP980102883A patent/AR012997A1/es not_active Application Discontinuation
- 1998-06-17 DZ DZ980131A patent/DZ2521A1/xx active
- 1998-06-17 AR ARP980102886A patent/AR015894A1/es not_active Application Discontinuation
- 1998-06-17 MA MA25122A patent/MA26511A1/fr unknown
- 1998-06-17 ZA ZA9805237A patent/ZA985237B/xx unknown
- 1998-06-17 TW TW087109619A patent/TW587937B/zh not_active IP Right Cessation
- 1998-06-18 UY UY25050A patent/UY25050A1/es unknown
- 1998-06-18 CO CO98034654A patent/CO4940454A1/es unknown
- 1998-06-18 PE PE1998000535A patent/PE104499A1/es not_active Application Discontinuation
- 1998-06-18 IN IN1698DE1998 patent/IN189723B/en unknown
1999
- 1999-12-17 OA OA9900296A patent/OA11517A/en unknown
- 1999-12-17 NO NO996265A patent/NO996265L/no not_active Application Discontinuation
2000
- 2000-01-06 BG BG104059A patent/BG104059A/xx unknown

Also Published As

Publication number	Publication date
ID23951A (id)	2000-06-08
GB9712866D0 (en)	1997-08-20
HUP0003260A3 (en)	2001-12-28
AU8216398A (en)	1999-01-04
CN1133431C (zh)	2004-01-07
DZ2521A1 (fr)	2003-02-08
TR199903095T2 (xx)	2000-08-21
AP1287A (en)	2004-06-26
ZA985237B (en)	2000-02-17
KR20010013843A (ko)	2001-02-26
HUP0003260A2 (hu)	2001-05-28
OA11517A (en)	2004-02-04
AP9901718A0 (en)	1999-12-31
EA200000042A1 (ru)	2000-08-28
MA26511A1 (fr)	2004-12-20
AR012997A1 (es)	2000-11-22
SK179399A3 (en)	2000-11-07
CN1260715A (zh)	2000-07-19
IL133143A0 (en)	2001-03-19
PL343123A1 (en)	2001-07-30
TW587937B (en)	2004-05-21
NO996265D0 (no)	1999-12-17
UY25050A1 (es)	2000-09-29
BR9810444A (pt)	2000-09-05
UA70299C2 (en)	2004-10-15
WO1998057636A1 (en)	1998-12-23
IN189723B (da)	2003-04-19
BG104059A (en)	2000-10-31
CO4940454A1 (es)	2000-07-24
NO996265L (no)	1999-12-17
EP0999837A1 (en)	2000-05-17
JP2002504138A (ja)	2002-02-05
CA2294141A1 (en)	1998-12-23
EA004800B1 (ru)	2004-08-26
AR015894A1 (es)	2001-05-30

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Legal Events

Date	Code	Title	Description
2003-09-25	FC	Refusal