PE104499A1 - Composicion farmaceutica de tiazolidindiona e insulina para el tratamiento de la diabetes - Google Patents
Composicion farmaceutica de tiazolidindiona e insulina para el tratamiento de la diabetesInfo
- Publication number
- PE104499A1 PE104499A1 PE1998000535A PE00053598A PE104499A1 PE 104499 A1 PE104499 A1 PE 104499A1 PE 1998000535 A PE1998000535 A PE 1998000535A PE 00053598 A PE00053598 A PE 00053598A PE 104499 A1 PE104499 A1 PE 104499A1
- Authority
- PE
- Peru
- Prior art keywords
- insulin
- diabetes
- treatment
- tiazolidindiona
- pharmaceutical composition
- Prior art date
Links
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 title abstract 6
- 102000004877 Insulin Human genes 0.000 title abstract 3
- 108090001061 Insulin Proteins 0.000 title abstract 3
- 206010012601 diabetes mellitus Diseases 0.000 title abstract 3
- 229940125396 insulin Drugs 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- -1 AMINO Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
Landscapes
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Endocrinology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Obesity (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Hematology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9712866.4A GB9712866D0 (en) | 1997-06-18 | 1997-06-18 | Novel method of treatment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE104499A1 true PE104499A1 (es) | 2000-01-13 |
Family
ID=10814527
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE1998000535A PE104499A1 (es) | 1997-06-18 | 1998-06-18 | Composicion farmaceutica de tiazolidindiona e insulina para el tratamiento de la diabetes |
Country Status (30)
| Country | Link |
|---|---|
| EP (1) | EP0999837A1 (mo) |
| JP (1) | JP2002504138A (mo) |
| KR (1) | KR20010013843A (mo) |
| CN (1) | CN1133431C (mo) |
| AP (1) | AP1287A (mo) |
| AR (2) | AR015894A1 (mo) |
| AU (1) | AU8216398A (mo) |
| BG (1) | BG104059A (mo) |
| BR (1) | BR9810444A (mo) |
| CA (1) | CA2294141A1 (mo) |
| CO (1) | CO4940454A1 (mo) |
| DZ (1) | DZ2521A1 (mo) |
| EA (1) | EA004800B1 (mo) |
| GB (1) | GB9712866D0 (mo) |
| HU (1) | HUP0003260A3 (mo) |
| ID (1) | ID23951A (mo) |
| IL (1) | IL133143A0 (mo) |
| IN (1) | IN189723B (mo) |
| MA (1) | MA26511A1 (mo) |
| NO (1) | NO996265L (mo) |
| OA (1) | OA11517A (mo) |
| PE (1) | PE104499A1 (mo) |
| PL (1) | PL343123A1 (mo) |
| SK (1) | SK179399A3 (mo) |
| TR (1) | TR199903095T2 (mo) |
| TW (1) | TW587937B (mo) |
| UA (1) | UA70299C2 (mo) |
| UY (1) | UY25050A1 (mo) |
| WO (1) | WO1998057636A1 (mo) |
| ZA (1) | ZA985237B (mo) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6291495B1 (en) * | 1997-02-24 | 2001-09-18 | Robert B. Rieveley | Method and composition for the treatment of diabetes |
| US7045519B2 (en) | 1998-06-19 | 2006-05-16 | Chiron Corporation | Inhibitors of glycogen synthase kinase 3 |
| TWI249401B (en) | 1999-04-14 | 2006-02-21 | Takeda Chemical Industries Ltd | Agent for improving ketosis |
| DE60004658T2 (de) | 1999-04-23 | 2004-06-24 | Smithkline Beecham Plc, Brentford | Thiazolidindionderivat und seine verwendung als antidiabetikum |
| USRE40876E1 (en) | 1999-06-21 | 2009-08-18 | Eli Lilly And Company | Method for treating non-insulin dependent diabetes using thiazolidinediones with glucagonlike peptide-1 and agonists thereof |
| WO2001000223A2 (en) * | 1999-06-25 | 2001-01-04 | Minimed Inc. | Multiple agent diabetes therapy |
| US6468507B1 (en) * | 2000-05-01 | 2002-10-22 | Aeropharm Technology, Inc. | Non-aqueous aerosol formulation comprising rosiglitazone maleate, a non-aqueous carrier, and an amino acid stabilizer |
| GB0023970D0 (en) * | 2000-09-29 | 2000-11-15 | Smithkline Beecham Plc | Novel pharmaceutical |
| AU2002248464A1 (en) | 2001-02-21 | 2002-09-12 | Medtronic Minimed, Inc. | Stabilized insulin formulations |
| US6531461B1 (en) | 2001-06-04 | 2003-03-11 | Louis Obyo Obyo Nelson | Medicament for the treatment of diabetes |
| US20020198203A1 (en) * | 2001-06-07 | 2002-12-26 | Wyeth | Combination of a PTPase inhibitor and a thiazolidinedione agent |
| US6737401B2 (en) | 2001-06-28 | 2004-05-18 | Metronic Minimed, Inc. | Methods of evaluating protein formulation stability and surfactant-stabilized insulin formulations derived therefrom |
| CN1711084B (zh) * | 2002-11-08 | 2010-04-28 | 霍夫曼-拉罗奇有限公司 | 作为ppar激动剂的取代4-烷氧基噁唑衍生物 |
| US7264813B2 (en) | 2003-09-24 | 2007-09-04 | Nikken Sohonsha Corporation | Therapeutic uses of Dunaliella powder |
| CN102389427A (zh) * | 2011-10-10 | 2012-03-28 | 成都恒瑞制药有限公司 | 含有罗格列酮和盐酸西替利嗪的固体口服制剂 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU679572B2 (en) * | 1993-09-15 | 1997-07-03 | Daiichi Sankyo Company, Limited | Use of thiazolidinediones to prevent or delay onset of NIDDM |
| JPH11510508A (ja) * | 1995-08-10 | 1999-09-14 | ワーナー−ランバート・コンパニー | インシュリン非依存性真性糖尿病患者に投与される外来インシュリンの量を減らす方法 |
| ATE259227T1 (de) * | 1995-09-18 | 2004-02-15 | Ligand Pharm Inc | Behandlung von niddm (nichtinsulinabhängige diabetes mellitus) mit rxr agonisten |
-
1997
- 1997-06-18 GB GBGB9712866.4A patent/GB9712866D0/en active Pending
-
1998
- 1998-06-15 AU AU82163/98A patent/AU8216398A/en not_active Abandoned
- 1998-06-15 PL PL98343123A patent/PL343123A1/xx unknown
- 1998-06-15 CN CNB988062232A patent/CN1133431C/zh not_active Expired - Fee Related
- 1998-06-15 CA CA002294141A patent/CA2294141A1/en not_active Abandoned
- 1998-06-15 BR BR9810444-6A patent/BR9810444A/pt not_active IP Right Cessation
- 1998-06-15 UA UA99126881A patent/UA70299C2/uk unknown
- 1998-06-15 JP JP50375799A patent/JP2002504138A/ja not_active Ceased
- 1998-06-15 AP APAP/P/1999/001718A patent/AP1287A/en active
- 1998-06-15 HU HU0003260A patent/HUP0003260A3/hu unknown
- 1998-06-15 EP EP98932169A patent/EP0999837A1/en not_active Withdrawn
- 1998-06-15 ID IDW991627A patent/ID23951A/id unknown
- 1998-06-15 WO PCT/EP1998/003692 patent/WO1998057636A1/en not_active Ceased
- 1998-06-15 SK SK1793-99A patent/SK179399A3/sk unknown
- 1998-06-15 IL IL13314398A patent/IL133143A0/xx unknown
- 1998-06-15 TR TR1999/03095T patent/TR199903095T2/xx unknown
- 1998-06-15 KR KR1019997011864A patent/KR20010013843A/ko not_active Ceased
- 1998-06-15 EA EA200000042A patent/EA004800B1/ru not_active IP Right Cessation
- 1998-06-17 AR ARP980102886A patent/AR015894A1/es not_active Application Discontinuation
- 1998-06-17 MA MA25122A patent/MA26511A1/fr unknown
- 1998-06-17 DZ DZ980131A patent/DZ2521A1/xx active
- 1998-06-17 ZA ZA9805237A patent/ZA985237B/xx unknown
- 1998-06-17 AR ARP980102883A patent/AR012997A1/es not_active Application Discontinuation
- 1998-06-17 TW TW087109619A patent/TW587937B/zh not_active IP Right Cessation
- 1998-06-18 CO CO98034654A patent/CO4940454A1/es unknown
- 1998-06-18 PE PE1998000535A patent/PE104499A1/es not_active Application Discontinuation
- 1998-06-18 UY UY25050A patent/UY25050A1/es unknown
- 1998-06-18 IN IN1698DE1998 patent/IN189723B/en unknown
-
1999
- 1999-12-17 NO NO996265A patent/NO996265L/no not_active Application Discontinuation
- 1999-12-17 OA OA9900296A patent/OA11517A/en unknown
-
2000
- 2000-01-06 BG BG104059A patent/BG104059A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN1133431C (zh) | 2004-01-07 |
| AP1287A (en) | 2004-06-26 |
| UY25050A1 (es) | 2000-09-29 |
| NO996265D0 (no) | 1999-12-17 |
| BG104059A (en) | 2000-10-31 |
| HUP0003260A2 (hu) | 2001-05-28 |
| ZA985237B (en) | 2000-02-17 |
| EA004800B1 (ru) | 2004-08-26 |
| CO4940454A1 (es) | 2000-07-24 |
| NO996265L (no) | 1999-12-17 |
| AR015894A1 (es) | 2001-05-30 |
| ID23951A (id) | 2000-06-08 |
| PL343123A1 (en) | 2001-07-30 |
| SK179399A3 (en) | 2000-11-07 |
| EP0999837A1 (en) | 2000-05-17 |
| JP2002504138A (ja) | 2002-02-05 |
| GB9712866D0 (en) | 1997-08-20 |
| AR012997A1 (es) | 2000-11-22 |
| MA26511A1 (fr) | 2004-12-20 |
| IL133143A0 (en) | 2001-03-19 |
| CN1260715A (zh) | 2000-07-19 |
| EA200000042A1 (ru) | 2000-08-28 |
| OA11517A (en) | 2004-02-04 |
| CA2294141A1 (en) | 1998-12-23 |
| TR199903095T2 (xx) | 2000-08-21 |
| AU8216398A (en) | 1999-01-04 |
| TW587937B (en) | 2004-05-21 |
| HUP0003260A3 (en) | 2001-12-28 |
| KR20010013843A (ko) | 2001-02-26 |
| DZ2521A1 (fr) | 2003-02-08 |
| IN189723B (mo) | 2003-04-19 |
| UA70299C2 (en) | 2004-10-15 |
| BR9810444A (pt) | 2000-09-05 |
| AP9901718A0 (en) | 1999-12-31 |
| WO1998057636A1 (en) | 1998-12-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC | Refusal |