PE20081114A1 - Composiciones farmaceuticas bioadhesivas de agente dual para uso topico - Google Patents

Composiciones farmaceuticas bioadhesivas de agente dual para uso topico

Info

Publication number
PE20081114A1
PE20081114A1 PE2007001327A PE2007001327A PE20081114A1 PE 20081114 A1 PE20081114 A1 PE 20081114A1 PE 2007001327 A PE2007001327 A PE 2007001327A PE 2007001327 A PE2007001327 A PE 2007001327A PE 20081114 A1 PE20081114 A1 PE 20081114A1
Authority
PE
Peru
Prior art keywords
pharmaceutical compositions
topical use
bioadhesive pharmaceutical
dual agent
concentration
Prior art date
Application number
PE2007001327A
Other languages
English (en)
Inventor
Jonathan Bortz
R Saul Levinson
Jisheng Ge
Jeremy Donald Wang
Original Assignee
Drugtech Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Drugtech Corp filed Critical Drugtech Corp
Publication of PE20081114A1 publication Critical patent/PE20081114A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

SE REFIERE A UNA COMPOSICION FARMACEUTICA BIOADHESIVA QUE SE UNE A UNA SUPERFICIE DE LA MUCOSA ORAL QUE COMPRENDE: A) FENITOINA QUE SE ENCUENTRA EN UNA CONCENTRACION DE 1 A 400MG/ML Y B) UN ANALGESICO OPIOIDE TAL COMO CODEINA, HIDROCODONA, SULFATO DE MORFINA QUE SE ENCUENTRA EN UNA CONCENTRACION DE 1 A 200MG/ML, EN DONDE LA DISTRIBUCION DE LOS COMPONENTES ES SOBRE LA SUPERFICIE DE LA MUCOSA SIN UNA ABSORCION SISTEMICA SUBSTANCIAL. DICHA COMPOSICION CONTIENE UNA FASE INTERNA NO LIPOIDE Y UNA FASE EXTERNA LIPOIDE QUE ES BIOADHESIVA Y EXHIBE RETENCION SOBRE LA SUPERFICIE DE LA MUCOSA ORAL POR UN PERIODO DE 0,5H A 24H SIENDO UTIL PARA EL TRATAMIENTO DE MUCOSITIS ORAL
PE2007001327A 2006-10-05 2007-10-02 Composiciones farmaceuticas bioadhesivas de agente dual para uso topico PE20081114A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US82831906P 2006-10-05 2006-10-05

Publications (1)

Publication Number Publication Date
PE20081114A1 true PE20081114A1 (es) 2008-08-28

Family

ID=39322783

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2007001327A PE20081114A1 (es) 2006-10-05 2007-10-02 Composiciones farmaceuticas bioadhesivas de agente dual para uso topico

Country Status (5)

Country Link
US (1) US20080299050A1 (es)
AR (1) AR063109A1 (es)
CL (1) CL2007002837A1 (es)
PE (1) PE20081114A1 (es)
WO (1) WO2008060764A2 (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6057287A (en) 1994-01-11 2000-05-02 Dyax Corp. Kallikrein-binding "Kunitz domain" proteins and analogues thereof
WO2003103475A2 (en) 2002-06-07 2003-12-18 Dyax Corp. Prevention and reduction of blood loss
US7153829B2 (en) 2002-06-07 2006-12-26 Dyax Corp. Kallikrein-inhibitor therapies
JP2005537006A (ja) 2002-08-28 2005-12-08 ダイアックス、コープ 臓器及び組織の保存方法
US7235530B2 (en) 2004-09-27 2007-06-26 Dyax Corporation Kallikrein inhibitors and anti-thrombolytic agents and uses thereof
CA2744235A1 (en) 2009-01-06 2010-07-15 Dyax Corp. Treatment of mucositis with kallikrein inhibitors
US8906883B2 (en) 2009-06-10 2014-12-09 Exthera Ab Treatment of oral mucositis by administering an ionic complex of chitosan and a negatively charged polysaccharide selected from heparin, heparan sulfate and dextran sulfate
US8829020B2 (en) 2009-07-16 2014-09-09 Mallinckrodt Llc Compounds and compositions for use in phototherapy and in treatment of ocular neovascular disease and cancers
EP3459564B1 (en) 2010-01-06 2021-10-27 Takeda Pharmaceutical Company Limited Plasma kallikrein binding proteins
CA2823776A1 (en) 2011-01-06 2012-07-12 Dyax Corp. Plasma kallikrein binding proteins
SMT202100228T1 (it) 2011-04-29 2021-05-07 Moberg Pharma Ab Composizioni farmaceutiche comprendenti un anestetico locale come bupivacaina per somministrazione locale alla bocca o alla gola
EP2874824B1 (en) 2012-07-23 2025-04-30 Crayola, LLC Dissolvable films and methods of using the same
EA201591755A1 (ru) * 2013-03-14 2016-03-31 3 ИН 1 ДЕНТАЛ ПиЭлЭлСи Композиции для лечения ксеростомии и для лечения зубов
US9433644B2 (en) 2013-07-25 2016-09-06 Rutgilli Pharmaceuticals, Llc Formulations and methods for treating oral inflammation, injury, or pain
WO2015101693A1 (es) * 2013-12-31 2015-07-09 Servicio Andaluz De Salud Composiciones y preparaciones combinadas para el tratamiento de las algias orofaríngeas
US11103546B2 (en) 2014-01-29 2021-08-31 Vita Ice Therapeutics Llc Edible oil compositions to treat oral complications and methods of using same
US9763934B2 (en) * 2014-03-05 2017-09-19 Professional Compounding Centers Of America Synergistic effect of poloxamer-based composition and itraconazole on fungus and yeast
IL295414B2 (en) 2014-03-27 2026-02-01 Takeda Pharmaceuticals Co Compositions and methods for treating macular edema due to diabetes
AU2016366557B2 (en) 2015-12-11 2024-01-25 Takeda Pharmaceutical Company Limited Plasma kallikrein inhibitors and uses thereof for treating hereditary angioedema attack
US12528880B2 (en) 2020-01-13 2026-01-20 Takeda Pharmaceutical Company Limited Plasma kallikrein inhibitors and uses thereof for treating pediatric hereditary angioedema attack

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5589480A (en) * 1994-08-17 1996-12-31 Elkhoury; George F. Topical application of opioid analgesic drugs such as morphine
US6274168B1 (en) * 1999-02-23 2001-08-14 Mylan Pharmaceuticals Inc. Phenytoin sodium pharmaceutical compositions
US20020013331A1 (en) * 2000-06-26 2002-01-31 Williams Robert O. Methods and compositions for treating pain of the mucous membrane
US6906038B2 (en) * 2001-08-29 2005-06-14 Abbott Laboratories Methods for alleviating mucositis
WO2004005338A1 (en) * 2002-07-08 2004-01-15 Genova, Ltd. Secreted peptides

Also Published As

Publication number Publication date
WO2008060764A2 (en) 2008-05-22
US20080299050A1 (en) 2008-12-04
AR063109A1 (es) 2008-12-30
CL2007002837A1 (es) 2008-07-18
WO2008060764A3 (en) 2008-07-24

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal