PE20141068A1 - Formulaciones topicas de tipo suspension que comprenden depsipeptido ciclico - Google Patents

Formulaciones topicas de tipo suspension que comprenden depsipeptido ciclico

Info

Publication number
PE20141068A1
PE20141068A1 PE2013002371A PE2013002371A PE20141068A1 PE 20141068 A1 PE20141068 A1 PE 20141068A1 PE 2013002371 A PE2013002371 A PE 2013002371A PE 2013002371 A PE2013002371 A PE 2013002371A PE 20141068 A1 PE20141068 A1 PE 20141068A1
Authority
PE
Peru
Prior art keywords
cyclic depsipeptide
formulations including
including cyclic
type formulations
topical suspension
Prior art date
Application number
PE2013002371A
Other languages
English (en)
Inventor
Claire Haug
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46148908&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20141068(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of PE20141068A1 publication Critical patent/PE20141068A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/15—Depsipeptides; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

SE REFIERE A UNA COMPOSICION FARMACEUTICA TOPICA QUE COMPRENDE: A) UN DEPSIPEPTIDO CICLICO DE FORMULA (II); B) UNA MATRIZ HIDROFOBICA QUE INCLUYE UNO O MAS COMPUESTOS SELECCIONADO A PARTIR DE PARAFINAS, ACEITES VEGETALES, GRASAS ANIMALES, GLICERIDOS SINTETICOS, ENTRE OTROS; Y C) UN AGENTE DE CONSISTENCIA TAL COMO MIRISTATO DE ISOPROPILO. DICHA COMPOSICION ADEMAS COMPRENDE UNO O MAS EXCIPIENTES SELECCIONADOS DE ANTIOXIDANTES, AGENTES GELIFICANTES, REGULADORES, CONSERVADORES, ENTRE OTROS. DICHA COMPOSICION ES UTIL PARA EL TRATAMIENTO DE ENFERMEDADES INFLAMATORIAS Y/O HIPERPROLIFERATIVAS Y PRURITICAS DE LA PIEL
PE2013002371A 2011-04-20 2012-04-18 Formulaciones topicas de tipo suspension que comprenden depsipeptido ciclico PE20141068A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161477297P 2011-04-20 2011-04-20

Publications (1)

Publication Number Publication Date
PE20141068A1 true PE20141068A1 (es) 2014-09-04

Family

ID=46148908

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2013002371A PE20141068A1 (es) 2011-04-20 2012-04-18 Formulaciones topicas de tipo suspension que comprenden depsipeptido ciclico

Country Status (22)

Country Link
US (2) US8680054B2 (es)
EP (1) EP2699231B1 (es)
JP (1) JP5906304B2 (es)
KR (1) KR101612170B1 (es)
CN (1) CN103476396B (es)
AR (1) AR086109A1 (es)
AU (1) AU2012245960B2 (es)
BR (1) BR112013026698A2 (es)
CA (1) CA2833326A1 (es)
CL (1) CL2013003036A1 (es)
EA (1) EA201391555A1 (es)
ES (1) ES2651639T3 (es)
GT (1) GT201300257A (es)
IL (1) IL228863A0 (es)
MA (1) MA35158B1 (es)
MX (1) MX338156B (es)
PE (1) PE20141068A1 (es)
PH (1) PH12013502054A1 (es)
SG (1) SG11201402441WA (es)
TN (1) TN2013000386A1 (es)
TW (1) TW201247218A (es)
WO (1) WO2012143868A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY151973A (en) 2007-08-17 2014-07-31 Novartis Ag Cyclic depsipeptides
US8680054B2 (en) 2011-04-20 2014-03-25 Novartis Ag Suspension type topical formulations comprising cyclic depsipeptide
US8614289B2 (en) 2011-04-20 2013-12-24 Novartis Ag Processes for the manufacture of macrocyclic depsipeptides and new intermediates
US8987413B2 (en) 2012-10-09 2015-03-24 Novartis Ag Aldehyde acetal based processes for the manufacture of macrocyclic depsipeptides and new intermediates
US9067978B2 (en) 2012-10-09 2015-06-30 Novartis Ag Solution phase processes for the manufacture of macrocyclic depsipeptides and new intermediates
US9226890B1 (en) 2013-12-10 2016-01-05 Englewood Lab, Llc Polysilicone base for scar treatment
CN108888590A (zh) * 2018-08-06 2018-11-27 江苏知原药业有限公司 包含他克莫司的混悬类型的局部制剂
JP2023516754A (ja) * 2020-03-06 2023-04-20 ライフマックス ラボラトリーズ インコーポレイテッド 環状デプシペプチドの局所医薬製剤

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3043252C2 (de) 1980-11-15 1982-12-02 Degussa Ag, 6000 Frankfurt Cyclische Acetale von N-Acylglutaminsäure -γ- semialdehyden, Verfahren zu deren Herstellung und ihre Verwendung
US5595756A (en) 1993-12-22 1997-01-21 Inex Pharmaceuticals Corporation Liposomal compositions for enhanced retention of bioactive agents
DE4421113A1 (de) 1994-06-16 1995-12-21 Biotechnolog Forschung Gmbh Chondramide, Gewinnungsverfahren, Mittel mit Chondramiden und Mischkultur zur Chondramid-Gewinnung
DE19828043A1 (de) 1998-06-24 1999-12-30 Bayer Ag Ektoparasitizide Mittel
JP2000154198A (ja) 1998-11-20 2000-06-06 Nisshin Flour Milling Co Ltd 環状デプシペプチドの固相合成方法及びその中間体
JP2001131085A (ja) * 1999-08-25 2001-05-15 Saitama Daiichi Seiyaku Kk 経皮・経粘膜吸収用の医薬組成物
GB0108234D0 (en) 2001-04-02 2001-05-23 Pharma Mar Sa Process for producing trunkamide A compounds
US20040110228A1 (en) 2002-04-01 2004-06-10 Mcalpine Shelli R. Combinatorial organic synthesis of unique biologically active compounds
KR101205257B1 (ko) 2003-06-06 2012-11-27 아렉시스 악티에볼라그 피부 상태 또는 암 치료를 위한 ｓｃｃｅ 저해제로서의 융합된 헤테로사이클 화합물의 용도
GB0322140D0 (en) * 2003-09-22 2003-10-22 Pfizer Ltd Combinations
DE10358525A1 (de) * 2003-12-13 2005-07-07 Bayer Healthcare Ag Endoparasitizide Mittel zur topischen Applikation
EP1716248A1 (en) 2004-02-03 2006-11-02 Bayer HealthCare AG Diagnostics and therapeutics for diseases associated with kallikrein 7 (klk7)
CA2651796A1 (en) 2006-02-27 2007-09-07 Arizona Board Of Regents For And On Behalf Of Arizona State University Identification and use of novopeptides for the treatment of cancer
MY151973A (en) 2007-08-17 2014-07-31 Novartis Ag Cyclic depsipeptides
WO2009024528A1 (en) 2007-08-17 2009-02-26 Novartis Ag Use of cyclic depsipeptides to inhibit kallikrein 7
DE102007052391A1 (de) 2007-10-31 2009-05-07 Henkel Ag & Co. Kgaa Mattwachs
JP2010241784A (ja) * 2008-06-19 2010-10-28 Mitsubishi Tanabe Pharma Corp 経皮投与製剤
US20110112121A1 (en) * 2009-07-06 2011-05-12 Joerg Berghausen Pharmaceutical Compositions and Solid Forms
KR101004362B1 (ko) 2010-03-19 2010-12-28 가톨릭대학교 산학협력단 자가 면역 질환 예방 및 치료용 ＴＮＦ－α와 ＴＷＥＡＫ 이중 길항제
US20120064136A1 (en) 2010-09-10 2012-03-15 Nanobio Corporation Anti-aging and wrinkle treatment methods using nanoemulsion compositions
WO2012035468A2 (en) 2010-09-14 2012-03-22 Trima - Israel Pharmaceutical Products Maabarot Ltd. Foamable topical composition
KR20140005998A (ko) 2011-01-24 2014-01-15 안테리오스, 인코퍼레이티드 나노입자 조성물, 이의 제형, 및 그의 용도
EP2667854B1 (en) 2011-01-24 2019-01-16 Anterios, Inc. Nanoparticle compositions
US8614289B2 (en) 2011-04-20 2013-12-24 Novartis Ag Processes for the manufacture of macrocyclic depsipeptides and new intermediates
US8680054B2 (en) 2011-04-20 2014-03-25 Novartis Ag Suspension type topical formulations comprising cyclic depsipeptide
US9067978B2 (en) 2012-10-09 2015-06-30 Novartis Ag Solution phase processes for the manufacture of macrocyclic depsipeptides and new intermediates
US8987413B2 (en) 2012-10-09 2015-03-24 Novartis Ag Aldehyde acetal based processes for the manufacture of macrocyclic depsipeptides and new intermediates

Also Published As

Publication number Publication date
AR086109A1 (es) 2013-11-20
EA201391555A1 (ru) 2014-11-28
MX2013012187A (es) 2013-11-04
WO2012143868A1 (en) 2012-10-26
CA2833326A1 (en) 2012-10-26
TN2013000386A1 (en) 2015-01-20
US20140162959A1 (en) 2014-06-12
GT201300257A (es) 2015-02-19
MA35158B1 (fr) 2014-06-02
AU2012245960B2 (en) 2014-09-25
NZ615551A (en) 2015-08-28
IL228863A0 (en) 2013-12-31
CN103476396A (zh) 2013-12-25
AU2012245960A1 (en) 2013-10-17
US8680054B2 (en) 2014-03-25
MX338156B (es) 2016-04-05
BR112013026698A2 (pt) 2016-12-27
CL2013003036A1 (es) 2014-04-04
US9114110B2 (en) 2015-08-25
KR20130133295A (ko) 2013-12-06
PH12013502054A1 (en) 2013-12-16
TW201247218A (en) 2012-12-01
JP2014512377A (ja) 2014-05-22
US20120270796A1 (en) 2012-10-25
JP5906304B2 (ja) 2016-04-20
ES2651639T3 (es) 2018-01-29
CN103476396B (zh) 2015-08-05
SG11201402441WA (en) 2014-09-26
EP2699231A1 (en) 2014-02-26
KR101612170B1 (ko) 2016-04-12
EP2699231B1 (en) 2017-09-13

Similar Documents

Publication Publication Date Title
PE20141068A1 (es) Formulaciones topicas de tipo suspension que comprenden depsipeptido ciclico
PE20151982A1 (es) Derivados de bencimidazolona como inhibidores del bromodominio
PE20142367A1 (es) Formulaciones de imiquimod
MX2016007067A (es) Microcapsulas lipidicas que comprenden de preferencia un retinoide y composicion que las contiene, su procedimiento de preparacion y su uso en dermatologia.
BR122021018243A8 (pt) Composição tópica de baixo ph e método para aumentar a aplicação tópica de um ingrediente ativo cosmeticamente aceitável
EP3639832A4 (en) USE OF A COMPOSITION WITH EXOSOME FROM ADAPTIVE TISSUE STEM CELLS AS AN ACTIVE INGREDIENT TO RELIEVE DERMATITIS
CR20160212A (es) Composiciones y métodos para modular los receptores x farnesoides
PE20150200A1 (es) Formulacion de anticuerpos
PE20130216A1 (es) Formulacion topica para un inhibidor de jak
PE20151786A1 (es) Compuestos heterociclicos y sus usos
BRPI0925036B8 (pt) uso de trans-t-butil ciclo-hexanol, composição cosmética, medicamento, seus usos e processos para tratar irritação na pele
BR112012023421A2 (pt) composição farmacêutica para tratamento de aumento de pressão intraocular
UY35040A (es) Pirrolopirimidinilamino-benzotiazolonas sustituidas
EA201391521A1 (ru) Композиции и способы для ингибирования и/или модулирования эффекторных t-клеток, участвующих в воспалительном нейродегенеративном заболевании
MX2019007811A (es) Composicion anhidra que comprende una sal de magnesio.
MX348064B (es) Imidazopiridazinas sustituidas con amino.
MX2016011529A (es) Formulacion para analogos anticolinergicos suaves.
CL2019002172A1 (es) Agente terapéutico para enfermedades del hígado.
BR112012015433B8 (pt) composição farmacêutica substancialmente anidra para aplicação cutânea
UY35338A (es) Compuestos bicíclicos moduladores de la actividad de s1p1 y composiciones farmacéuticas que los contienen
BR112012012649A2 (pt) agente indutor de beta-defensina humana, formulação, e, usos de um agente indutor de beta-defensiva humana, e de pelo menos uma gordura ou óleo de um triglicerídeo de ácido graxo essencial ou de um derivado do mesmo.
BR112015025726A2 (pt) composição multi-funcional para formulações cosméticas
BR112014014207A2 (pt) análogos de magnolol solubilizados
AR083095A1 (es) Cocristal de aprepitant l-prolina y composicion farmaceutica
MX2017005163A (es) Composiciones de liberación prolongada de onapristona y métodos.

Legal Events

Date Code Title Description
FD Application declared void or lapsed