PE73199A1 - Metodo para fabricar sertindol - Google Patents

Metodo para fabricar sertindol

Info

Publication number: PE73199A1
Authority: PE; Peru
Prior art keywords: indole; nuorophenyl; glycine; chloro; reduction
Prior art date: 1997-05-09

Application number

PE00035498A

Other languages

English (en)

Spanish (es)

Inventor

Sommer Michael Bech

Original Assignee

Lundbeck & Co As H

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-05-09

Filing date

1998-05-08

Publication date

1999-08-09

1998-05-08 Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H

1999-08-09 Publication of PE73199A1 publication Critical patent/PE73199A1/es

Links

GZKLJWGUPQBVJQ-UHFFFAOYSA-N sertindole Chemical compound C1=CC(F)=CC=C1N1C2=CC=C(Cl)C=C2C(C2CCN(CCN3C(NCC3)=O)CC2)=C1 GZKLJWGUPQBVJQ-UHFFFAOYSA-N 0.000 title abstract 4
238000000034 method Methods 0.000 title abstract 3
238000004519 manufacturing process Methods 0.000 title abstract 2
DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 abstract 4
SIKJAQJRHWYJAI-UHFFFAOYSA-N Indole Chemical compound C1=CC=C2NC=CC2=C1 SIKJAQJRHWYJAI-UHFFFAOYSA-N 0.000 abstract 4
QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 3
229960000652 sertindole Drugs 0.000 abstract 3
VRJHQPZVIGNGMX-UHFFFAOYSA-N 4-piperidinone Chemical compound O=C1CCNCC1 VRJHQPZVIGNGMX-UHFFFAOYSA-N 0.000 abstract 2
239000004471 Glycine Substances 0.000 abstract 2
JBOPQACSHPPKEP-UHFFFAOYSA-N Indoxyl acetate Chemical compound C1=CC=C2C(OC(=O)C)=CNC2=C1 JBOPQACSHPPKEP-UHFFFAOYSA-N 0.000 abstract 2
229910052783 alkali metal Inorganic materials 0.000 abstract 2
-1 alkalimetal salt Chemical class 0.000 abstract 2
PZOUSPYUWWUPPK-UHFFFAOYSA-N indole Natural products CC1=CC=CC2=C1C=CN2 PZOUSPYUWWUPPK-UHFFFAOYSA-N 0.000 abstract 2
RKJUIXBNRJVNHR-UHFFFAOYSA-N indolenine Natural products C1=CC=C2CC=NC2=C1 RKJUIXBNRJVNHR-UHFFFAOYSA-N 0.000 abstract 2
QVTQYSFCFOGITD-UHFFFAOYSA-N 2,5-dichlorobenzoic acid Chemical compound OC(=O)C1=CC(Cl)=CC=C1Cl QVTQYSFCFOGITD-UHFFFAOYSA-N 0.000 abstract 1
ZFIMCCCQJDZLCT-UHFFFAOYSA-N 2-(4-fluoroanilino)acetic acid Chemical compound OC(=O)CNC1=CC=C(F)C=C1 ZFIMCCCQJDZLCT-UHFFFAOYSA-N 0.000 abstract 1
WLQZFXJVVNNEJU-UHFFFAOYSA-N 5-chloro-1-(4-fluorophenyl)-3-(1,2,3,6-tetrahydropyridin-4-yl)indole Chemical compound C1=CC(F)=CC=C1N1C2=CC=C(Cl)C=C2C(C=2CCNCC=2)=C1 WLQZFXJVVNNEJU-UHFFFAOYSA-N 0.000 abstract 1
RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 abstract 1
239000003054 catalyst Substances 0.000 abstract 1
238000006243 chemical reaction Methods 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
229910052802 copper Inorganic materials 0.000 abstract 1
239000010949 copper Substances 0.000 abstract 1
230000008030 elimination Effects 0.000 abstract 1
238000003379 elimination reaction Methods 0.000 abstract 1
238000011031 large-scale manufacturing process Methods 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
239000000376 reactant Substances 0.000 abstract 1
239000002904 solvent Substances 0.000 abstract 1

Landscapes

Indole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

PE00035498A 1997-05-09 1998-05-08 Metodo para fabricar sertindol PE73199A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DK53697		1997-05-09

Publications (1)

Publication Number	Publication Date
PE73199A1 true PE73199A1 (es)	1999-08-09

Family

ID=8094655

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PE00035498A PE73199A1 (es)	1997-05-09	1998-05-08	Metodo para fabricar sertindol

Country Status (13)

Country	Link
AR (1)	AR012661A1 (2)
CA (1)	CA2486883C (2)
CO (1)	CO4950521A1 (2)
DZ (1)	DZ2483A1 (2)
IL (1)	IL156180A0 (2)
IN (3)	IN187834B (2)
JO (1)	JO2015B1 (2)
MA (1)	MA25584A1 (2)
MY (1)	MY124162A (2)
PE (1)	PE73199A1 (2)
TN (1)	TNSN98063A1 (2)
TW (1)	TW487692B (2)
ZA (1)	ZA983726B (2)

1998
- 1998-04-27 MY MYPI9801885 patent/MY124162A/en unknown
- 1998-05-01 IN IN948MA1998 patent/IN187834B/en unknown
- 1998-05-04 ZA ZA983726A patent/ZA983726B/xx unknown
- 1998-05-04 CO CO98024289A patent/CO4950521A1/es unknown
- 1998-05-05 AR ARP980102090 patent/AR012661A1/es active IP Right Grant
- 1998-05-05 DZ DZ980094A patent/DZ2483A1/xx active
- 1998-05-07 JO JO19982015A patent/JO2015B1/en active
- 1998-05-07 CA CA002486883A patent/CA2486883C/en not_active Expired - Fee Related
- 1998-05-07 IL IL15618098A patent/IL156180A0/xx not_active IP Right Cessation
- 1998-05-08 PE PE00035498A patent/PE73199A1/es not_active Application Discontinuation
- 1998-05-08 TN TNTNSN98063A patent/TNSN98063A1/fr unknown
- 1998-05-11 MA MA25070A patent/MA25584A1/fr unknown
- 1998-07-02 TW TW87110712A patent/TW487692B/zh not_active IP Right Cessation
2000
- 2000-09-08 IN IN777MA2000 patent/IN190902B/en unknown
- 2000-09-18 IN IN776MA2000 patent/IN192270B/en unknown

Also Published As

Publication number	Publication date
TW487692B (en)	2002-05-21
JO2015B1 (en)	1999-05-15
CO4950521A1 (es)	2000-09-01
ZA983726B (en)	1998-11-24
IN192270B (2)	2004-03-27
DZ2483A1 (fr)	2004-09-05
AR012661A1 (es)	2000-11-08
MY124162A (en)	2006-06-30
IN187834B (2)	2002-06-29
IN190902B (2)	2003-08-30
IL156180A0 (en)	2003-12-23
CA2486883C (en)	2009-04-28
CA2486883A1 (en)	1998-11-19
MA25584A1 (fr)	2002-12-31
TNSN98063A1 (fr)	2005-03-15

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Legal Events

Date	Code	Title	Description
2001-11-30	FG	Grant, registration
2010-12-21	FD	Application declared void or lapsed