PH12021550037A1 - Pharmaceutical composition in the form of a chewable tablet of diosmin or of a flavonoid moiety - Google Patents

Pharmaceutical composition in the form of a chewable tablet of diosmin or of a flavonoid moiety

Info

Publication number
PH12021550037A1
PH12021550037A1 PH12021550037A PH12021550037A PH12021550037A1 PH 12021550037 A1 PH12021550037 A1 PH 12021550037A1 PH 12021550037 A PH12021550037 A PH 12021550037A PH 12021550037 A PH12021550037 A PH 12021550037A PH 12021550037 A1 PH12021550037 A1 PH 12021550037A1
Authority
PH
Philippines
Prior art keywords
pharmaceutical composition
diosmin
chewable tablet
flavonoid moiety
pcnt
Prior art date
Application number
PH12021550037A
Inventor
St‚Phanie Marsas
Jean-Manuel Pean
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Servier Lab filed Critical Servier Lab
Publication of PH12021550037A1 publication Critical patent/PH12021550037A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2095Tabletting processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nutrition Science (AREA)
  • Organic Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Physiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Disclosed is a pharmaceutical composition in the form of a chewable tablet containing a high dose of micronized diosmin. Said pharmaceutical composition comprises micronized diosmin amounting to 20 pcnt to 80 pcnt of the total weight of the pharmaceutical composition. The disclosed pharmaceutical composition is used in the treatment of venous insufficiency and hemorrhoidal crises.
PH12021550037A 2018-07-20 2021-01-07 Pharmaceutical composition in the form of a chewable tablet of diosmin or of a flavonoid moiety PH12021550037A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR1856769A FR3083980B1 (en) 2018-07-20 2018-07-20 PHARMACEUTICAL COMPOSITION IN THE FORM OF A CHEWABLE TABLET OF DIOSMINE OR A FLAVONOIC FRACTION
PCT/EP2019/069498 WO2020016408A1 (en) 2018-07-20 2019-07-19 Pharmaceutical composition in the form of a chewable tablet of diosmin or of a flavonoid moiety

Publications (1)

Publication Number Publication Date
PH12021550037A1 true PH12021550037A1 (en) 2021-09-27

Family

ID=65243687

Family Applications (1)

Application Number Title Priority Date Filing Date
PH12021550037A PH12021550037A1 (en) 2018-07-20 2021-01-07 Pharmaceutical composition in the form of a chewable tablet of diosmin or of a flavonoid moiety

Country Status (36)

Country Link
EP (2) EP3823588B1 (en)
KR (1) KR20210034036A (en)
CN (2) CN119345141A (en)
AR (1) AR117612A1 (en)
AU (1) AU2019306315B2 (en)
BR (1) BR112021000440A2 (en)
CA (1) CA3106495C (en)
CL (1) CL2021000083A1 (en)
CO (1) CO2021000115A2 (en)
CR (1) CR20210023A (en)
DK (1) DK3823588T3 (en)
EA (1) EA202190269A1 (en)
EC (1) ECSP21001232A (en)
ES (1) ES2991941T3 (en)
FI (1) FI3823588T3 (en)
FR (1) FR3083980B1 (en)
GE (1) GEP20237532B (en)
HR (1) HRP20250037T1 (en)
HU (1) HUE069700T2 (en)
JO (1) JOP20210003A1 (en)
LT (1) LT3823588T (en)
MA (1) MA53159B1 (en)
MD (1) MD3823588T2 (en)
MX (1) MX2021000763A (en)
MY (1) MY200586A (en)
NI (1) NI202100002A (en)
PE (1) PE20210929A1 (en)
PH (1) PH12021550037A1 (en)
PL (1) PL3823588T3 (en)
PT (1) PT3823588T (en)
RS (1) RS66288B1 (en)
SG (1) SG11202100181YA (en)
SI (1) SI3823588T1 (en)
TW (1) TWI831808B (en)
UA (1) UA128677C2 (en)
WO (1) WO2020016408A1 (en)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2661610B1 (en) * 1990-05-02 1994-09-30 Rhone Poulenc Sante NOVEL LYOPHILIZED FORM OF DIOSMINE AND ITS PREPARATION.
FR2661830B1 (en) * 1990-05-11 1992-09-04 Corbiere Jerome NOVEL PHARMACEUTICAL COMPOSITIONS BASED ON FLAVONOSIDE.
FR2726469B1 (en) 1994-11-08 1996-12-13 Adir PHARMACEUTICAL COMPOSITION FOR ORAL ADMINISTRATION OF FLAVONOIDS
FR2845597B1 (en) * 2002-10-11 2005-03-11 Innothera Lab Sa DRY ORAL FORMULATION CONTAINING DIOSMINE AS A PHARMACEUTICAL FORM OF A TABLET TO BE CROQUERED
ITMI20050517A1 (en) 2005-03-30 2006-09-30 Therapicon Srl PHARMACEUTICAL COMPOSITION OF A TYPICAL MICROCRYSTALLINE FRACTION OF FLAVONOIDS
FR2999934B1 (en) * 2012-12-21 2015-02-20 Servier Lab PHARMACEUTICAL COMPOSITION IN THE FORM OF AN ORAL SUSPENSION COMPRISING A FLAVONOIC FRACTION AND XANTHAN GUM

Also Published As

Publication number Publication date
FR3083980A1 (en) 2020-01-24
CA3106495A1 (en) 2020-01-23
MA53159B1 (en) 2024-12-31
UA128677C2 (en) 2024-09-25
DK3823588T3 (en) 2025-01-02
FR3083980B1 (en) 2021-04-16
MA53159A (en) 2021-05-26
TW202019439A (en) 2020-06-01
WO2020016408A1 (en) 2020-01-23
GEP20237532B (en) 2023-08-25
HUE069700T2 (en) 2025-04-28
EP3823588A1 (en) 2021-05-26
CL2021000083A1 (en) 2021-07-30
PL3823588T3 (en) 2025-03-31
MX2021000763A (en) 2021-03-29
EP3823588B1 (en) 2024-10-23
KR20210034036A (en) 2021-03-29
CA3106495C (en) 2023-08-08
ES2991941T3 (en) 2024-12-05
AU2019306315A1 (en) 2021-02-11
SI3823588T1 (en) 2025-04-30
CR20210023A (en) 2021-02-22
EP4473977A2 (en) 2024-12-11
FI3823588T3 (en) 2024-12-27
MD3823588T2 (en) 2025-04-30
CN119345141A (en) 2025-01-24
TWI831808B (en) 2024-02-11
JOP20210003A1 (en) 2021-01-10
MY200586A (en) 2024-01-04
PE20210929A1 (en) 2021-05-19
PT3823588T (en) 2024-10-31
CN112423735A (en) 2021-02-26
ECSP21001232A (en) 2021-02-26
CO2021000115A2 (en) 2021-01-29
LT3823588T (en) 2024-11-11
NZ771968A (en) 2025-05-02
EA202190269A1 (en) 2021-06-15
AR117612A1 (en) 2021-08-18
HRP20250037T1 (en) 2025-03-14
AU2019306315B2 (en) 2023-03-09
RS66288B1 (en) 2025-01-31
BR112021000440A2 (en) 2021-04-06
SG11202100181YA (en) 2021-02-25
NI202100002A (en) 2021-06-22
GEAP202315564A (en) 2023-05-10
EP4473977A3 (en) 2025-03-05

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