PH18224A - Pyrimido(6,1-a)isoquinolin-4-one derivatives pharmaceutical compositions containing same and method of treatment thereof - Google Patents
Pyrimido(6,1-a)isoquinolin-4-one derivatives pharmaceutical compositions containing same and method of treatment thereofInfo
- Publication number
- PH18224A PH18224A PH28310A PH28310A PH18224A PH 18224 A PH18224 A PH 18224A PH 28310 A PH28310 A PH 28310A PH 28310 A PH28310 A PH 28310A PH 18224 A PH18224 A PH 18224A
- Authority
- PH
- Philippines
- Prior art keywords
- pyrimido
- isoquinolin
- treatment
- pharmaceutical compositions
- compositions containing
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- CIVQDIGHVMGTPD-UHFFFAOYSA-N pyrimido[6,1-a]isoquinolin-4-one Chemical class C1=CC=C2C=CN3C(=O)N=CC=C3C2=C1 CIVQDIGHVMGTPD-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
- C07F9/6509—Six-membered rings
- C07F9/650905—Six-membered rings having the nitrogen atoms in the positions 1 and 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN433/BOM/76A IN147624B (en) | 1976-12-10 | 1976-12-10 | |
| DE19772720085 DE2720085A1 (en) | 1977-05-05 | 1977-05-05 | PYRIMIDO (6.1-A) ISOCHINOLIN-2-ON DERIVATIVES |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PH18224A true PH18224A (en) | 1985-04-30 |
Family
ID=25771976
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PH28310A PH18224A (en) | 1976-12-10 | 1982-12-21 | Pyrimido(6,1-a)isoquinolin-4-one derivatives pharmaceutical compositions containing same and method of treatment thereof |
Country Status (6)
| Country | Link |
|---|---|
| AU (2) | AU527997B2 (en) |
| CA (1) | CA1140123A (en) |
| GB (1) | GB1597717A (en) |
| IE (1) | IE45850B1 (en) |
| NZ (1) | NZ185900A (en) |
| PH (1) | PH18224A (en) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3135831A1 (en) * | 1981-09-10 | 1983-04-28 | Hoechst Ag, 6230 Frankfurt | 9,10-SUBSTITUTED 2-MESITYLIMINO-3-ALKYL-3,4,6,7-TETRAHYDRO-2H-PYRIMIDO (6.1-A) ISOCHINOLIN-4-ONE, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS A MEDICINAL PRODUCT |
| ZW6284A1 (en) * | 1983-05-05 | 1985-10-30 | Hoffmann La Roche | Novel pyrimidone derivatives |
| CA2368413C (en) | 1999-03-31 | 2008-07-29 | Verona Pharma Plc | Derivatives of pyrimido[6,1-a]isoquinolin-4-one |
| GB201613054D0 (en) | 2016-07-28 | 2016-09-14 | Verona Pharma Plc | New compound and process |
| IL280075B2 (en) | 2018-07-13 | 2024-06-01 | Chia Tai Tianqing Pharmaceutical Group Co Ltd | Fused tri-cyclic compound as pde3/pde4 dual inhibitor |
| KR20240004495A (en) * | 2021-04-29 | 2024-01-11 | 쑤저우 선카디아 바이오파마수티컬즈 컴퍼니 리미티드 | Isoquinolone compounds and their uses |
| WO2023109802A1 (en) | 2021-12-14 | 2023-06-22 | 海思科医药集团股份有限公司 | Tricyclic fused heterocyclic pde3/4 dual inhibitor and use thereof |
| GB202202297D0 (en) | 2022-02-21 | 2022-04-06 | Verona Pharma Plc | Formulation production process |
| CN117946099A (en) * | 2022-10-28 | 2024-04-30 | 江苏恒瑞医药股份有限公司 | A pharmaceutically acceptable salt of isoquinolinone compound, crystal form and preparation method thereof |
| CN121620356A (en) | 2023-06-26 | 2026-03-06 | 维罗纳制药公司 | Comprises enkephalin particulate composition of (2) |
| CN120329302B (en) * | 2025-05-13 | 2026-05-01 | 广东医科大学 | Pyrimido [2,1-a:4,3-a' ] diisoquinoline compound and preparation method and application thereof |
-
1977
- 1977-12-08 NZ NZ185900A patent/NZ185900A/en unknown
- 1977-12-09 AU AU31411/77A patent/AU527997B2/en not_active Expired
- 1977-12-09 IE IE2498/77A patent/IE45850B1/en unknown
- 1977-12-09 GB GB51331/77A patent/GB1597717A/en not_active Expired
- 1977-12-09 CA CA000292819A patent/CA1140123A/en not_active Expired
-
1982
- 1982-12-21 PH PH28310A patent/PH18224A/en unknown
-
1983
- 1983-06-16 AU AU15865/83A patent/AU1586583A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU527997B2 (en) | 1983-03-31 |
| IE45850L (en) | 1978-06-10 |
| AU1586583A (en) | 1983-12-22 |
| AU3141177A (en) | 1979-06-14 |
| NZ185900A (en) | 1981-04-24 |
| GB1597717A (en) | 1981-09-09 |
| CA1140123A (en) | 1983-01-25 |
| IE45850B1 (en) | 1982-12-15 |
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