PH18224A - Pyrimido(6,1-a)isoquinolin-4-one derivatives pharmaceutical compositions containing same and method of treatment thereof - Google Patents

Pyrimido(6,1-a)isoquinolin-4-one derivatives pharmaceutical compositions containing same and method of treatment thereof

Info

Publication number
PH18224A
PH18224A PH28310A PH28310A PH18224A PH 18224 A PH18224 A PH 18224A PH 28310 A PH28310 A PH 28310A PH 28310 A PH28310 A PH 28310A PH 18224 A PH18224 A PH 18224A
Authority
PH
Philippines
Prior art keywords
pyrimido
isoquinolin
treatment
pharmaceutical compositions
compositions containing
Prior art date
Application number
PH28310A
Inventor
Bansi Lal
Bani Kanta Bhattacharya
Alihussein Nomanbha Dohadwalla
Noel John De Souza
Horst Dornauer
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IN433/BOM/76A external-priority patent/IN147624B/en
Priority claimed from DE19772720085 external-priority patent/DE2720085A1/en
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of PH18224A publication Critical patent/PH18224A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6509—Six-membered rings
    • C07F9/650905—Six-membered rings having the nitrogen atoms in the positions 1 and 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PH28310A 1976-12-10 1982-12-21 Pyrimido(6,1-a)isoquinolin-4-one derivatives pharmaceutical compositions containing same and method of treatment thereof PH18224A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN433/BOM/76A IN147624B (en) 1976-12-10 1976-12-10
DE19772720085 DE2720085A1 (en) 1977-05-05 1977-05-05 PYRIMIDO (6.1-A) ISOCHINOLIN-2-ON DERIVATIVES

Publications (1)

Publication Number Publication Date
PH18224A true PH18224A (en) 1985-04-30

Family

ID=25771976

Family Applications (1)

Application Number Title Priority Date Filing Date
PH28310A PH18224A (en) 1976-12-10 1982-12-21 Pyrimido(6,1-a)isoquinolin-4-one derivatives pharmaceutical compositions containing same and method of treatment thereof

Country Status (6)

Country Link
AU (2) AU527997B2 (en)
CA (1) CA1140123A (en)
GB (1) GB1597717A (en)
IE (1) IE45850B1 (en)
NZ (1) NZ185900A (en)
PH (1) PH18224A (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3135831A1 (en) * 1981-09-10 1983-04-28 Hoechst Ag, 6230 Frankfurt 9,10-SUBSTITUTED 2-MESITYLIMINO-3-ALKYL-3,4,6,7-TETRAHYDRO-2H-PYRIMIDO (6.1-A) ISOCHINOLIN-4-ONE, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS A MEDICINAL PRODUCT
ZW6284A1 (en) * 1983-05-05 1985-10-30 Hoffmann La Roche Novel pyrimidone derivatives
DE60005493T2 (en) 1999-03-31 2004-07-01 Vernalis Ltd., Wokingham Pyrimido [6,1-A] ISOCHINOLINONDERIVATE
GB201613054D0 (en) 2016-07-28 2016-09-14 Verona Pharma Plc New compound and process
PT3822272T (en) 2018-07-13 2025-01-22 Chia Tai Tianqing Pharmaceutical Group Co Ltd Fused tri-cyclic compound as pde3/pde4 dual inhibitor
CN116917287A (en) * 2021-04-29 2023-10-20 苏州盛迪亚生物医药有限公司 Isoquinolinone compounds and their uses
TW202325301A (en) * 2021-12-14 2023-07-01 大陸商海思科醫藥集團股份有限公司 Tricyclic fused heterocyclic PDE3/4 dual inhibitor and use thereof
GB202202297D0 (en) 2022-02-21 2022-04-06 Verona Pharma Plc Formulation production process
CN117946099A (en) * 2022-10-28 2024-04-30 江苏恒瑞医药股份有限公司 A pharmaceutically acceptable salt of isoquinolinone compound, crystal form and preparation method thereof
AU2024309346C1 (en) 2023-06-26 2026-03-12 Verona Pharma Plc Particulate composition comprising ensifentrine

Also Published As

Publication number Publication date
AU1586583A (en) 1983-12-22
CA1140123A (en) 1983-01-25
IE45850L (en) 1978-06-10
GB1597717A (en) 1981-09-09
NZ185900A (en) 1981-04-24
IE45850B1 (en) 1982-12-15
AU3141177A (en) 1979-06-14
AU527997B2 (en) 1983-03-31

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