PH20393A - I-aroyl-5-oxo-2-pyrrolidinepropanoic acids and related esters - Google Patents

I-aroyl-5-oxo-2-pyrrolidinepropanoic acids and related esters

Info

Publication number
PH20393A
PH20393A PH29831A PH29831A PH20393A PH 20393 A PH20393 A PH 20393A PH 29831 A PH29831 A PH 29831A PH 29831 A PH29831 A PH 29831A PH 20393 A PH20393 A PH 20393A
Authority
PH
Philippines
Prior art keywords
aroyl
oxo
esters
amnesia
reversal
Prior art date
Application number
PH29831A
Other languages
English (en)
Inventor
Butler Donald Eugene
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of PH20393A publication Critical patent/PH20393A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
PH29831A 1982-11-15 1983-11-14 I-aroyl-5-oxo-2-pyrrolidinepropanoic acids and related esters PH20393A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/441,335 US4452990A (en) 1982-11-15 1982-11-15 1-Aroyl-5-oxo-2-pyrrolidinepropanoic acids and related esters

Publications (1)

Publication Number Publication Date
PH20393A true PH20393A (en) 1986-12-12

Family

ID=23752490

Family Applications (1)

Application Number Title Priority Date Filing Date
PH29831A PH20393A (en) 1982-11-15 1983-11-14 I-aroyl-5-oxo-2-pyrrolidinepropanoic acids and related esters

Country Status (20)

Country Link
US (1) US4452990A (de)
EP (1) EP0110575B1 (de)
JP (1) JPS59101461A (de)
KR (1) KR900005018B1 (de)
AT (1) ATE27272T1 (de)
AU (1) AU557068B2 (de)
CA (1) CA1215977A (de)
DE (1) DE3371628D1 (de)
DK (1) DK519783D0 (de)
ES (1) ES8600238A1 (de)
FI (1) FI77443C (de)
GR (1) GR78737B (de)
HU (1) HU190916B (de)
IE (1) IE56126B1 (de)
IL (1) IL70082A (de)
NO (1) NO161491C (de)
NZ (1) NZ206256A (de)
PH (1) PH20393A (de)
PT (1) PT77653B (de)
ZA (1) ZA838126B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5173489A (en) * 1986-04-10 1992-12-22 The Dupont Merck Pharmaceutical Co. α,α-disubstituted aromatics and heteroaromatics as cognition enhancers
US4760083A (en) * 1986-04-10 1988-07-26 E. I. Dupont De Nemours & Company 3,3-disubstituted indolines
US4876259A (en) * 1987-01-05 1989-10-24 E. I. Du Pont De Nemours And Company 3,3-disubstituted indolines
US5021439A (en) * 1988-10-31 1991-06-04 Takeda Chemical Industries, Ltd. Cerebral function ameliorating agents related to Tan-950 A
AT391692B (de) * 1989-04-24 1990-11-12 Fleischhacker Wilhelm Dr Enantiomerenreine, in position 1 alkylierte 5-oxo-2-pyrrolidinpropansaeuren und deren ester, deren herstellung und verwendung

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS535158A (en) * 1976-07-05 1978-01-18 Teijin Ltd Preparation of optical active alpha-alkylvenzylalcohol and its intermediates

Also Published As

Publication number Publication date
KR900005018B1 (ko) 1990-07-18
HU190916B (en) 1986-12-28
GR78737B (de) 1984-10-02
PT77653B (en) 1986-04-17
ES527241A0 (es) 1985-04-16
AU557068B2 (en) 1986-12-04
IE832475L (en) 1984-05-15
FI77443B (fi) 1988-11-30
NO834149L (no) 1984-05-16
NO161491C (no) 1989-08-23
KR840006622A (ko) 1984-12-01
CA1215977A (en) 1986-12-30
DE3371628D1 (en) 1987-06-25
JPS59101461A (ja) 1984-06-12
AU2087183A (en) 1984-05-24
FI834136A7 (fi) 1984-05-16
DK519783D0 (da) 1983-11-14
EP0110575B1 (de) 1987-05-20
FI834136A0 (fi) 1983-11-11
NO161491B (no) 1989-05-16
US4452990A (en) 1984-06-05
PT77653A (en) 1983-12-01
ES8600238A1 (es) 1985-04-16
ZA838126B (en) 1985-06-26
EP0110575A1 (de) 1984-06-13
IE56126B1 (en) 1991-04-24
IL70082A0 (en) 1984-01-31
FI77443C (fi) 1989-03-10
ATE27272T1 (de) 1987-06-15
IL70082A (en) 1987-07-31
NZ206256A (en) 1985-09-13

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