PH20457A - Sorbinil by optical resolution with aminopinane derivatives - Google Patents
Sorbinil by optical resolution with aminopinane derivativesInfo
- Publication number
- PH20457A PH20457A PH29803A PH29803A PH20457A PH 20457 A PH20457 A PH 20457A PH 29803 A PH29803 A PH 29803A PH 29803 A PH29803 A PH 29803A PH 20457 A PH20457 A PH 20457A
- Authority
- PH
- Philippines
- Prior art keywords
- sorbinil
- optical resolution
- aminopinane
- derivatives
- salt
- Prior art date
Links
- LXANPKRCLVQAOG-NSHDSACASA-N sorbinil Chemical compound C12=CC(F)=CC=C2OCC[C@@]21NC(=O)NC2=O LXANPKRCLVQAOG-NSHDSACASA-N 0.000 title abstract 5
- 229950004311 sorbinil Drugs 0.000 title abstract 5
- 230000003287 optical effect Effects 0.000 title abstract 2
- WXEJLHJZGPUQHN-UHFFFAOYSA-N 4,6,6-trimethylbicyclo[3.1.1]heptan-5-amine Chemical class CC1CCC2C(C)(C)C1(N)C2 WXEJLHJZGPUQHN-UHFFFAOYSA-N 0.000 title 1
- MUOITVAMHSVXLO-UHFFFAOYSA-N (4,6,6-trimethyl-3-bicyclo[3.1.1]heptanyl)methanamine Chemical class C1C(CN)C(C)C2C(C)(C)C1C2 MUOITVAMHSVXLO-UHFFFAOYSA-N 0.000 abstract 2
- LOUPRKONTZGTKE-WZBLMQSHSA-N Quinine Chemical class C([C@H]([C@H](C1)C=C)C2)C[N@@]1[C@@H]2[C@H](O)C1=CC=NC2=CC=C(OC)C=C21 LOUPRKONTZGTKE-WZBLMQSHSA-N 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000012141 concentrate Substances 0.000 abstract 1
- 239000012452 mother liquor Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
- Electrochromic Elements, Electrophoresis, Or Variable Reflection Or Absorption Elements (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyrane Compounds (AREA)
- Physical Water Treatments (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Control Of Turbines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US44068682A | 1982-11-10 | 1982-11-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PH20457A true PH20457A (en) | 1987-01-14 |
Family
ID=23749769
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PH29803A PH20457A (en) | 1982-11-10 | 1983-11-09 | Sorbinil by optical resolution with aminopinane derivatives |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0109231B1 (de) |
| AT (1) | ATE23046T1 (de) |
| CA (1) | CA1202310A (de) |
| DE (1) | DE3367103D1 (de) |
| HU (1) | HU188383B (de) |
| IE (1) | IE56212B1 (de) |
| PH (1) | PH20457A (de) |
| RO (1) | RO87830A2 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4620019A (en) * | 1984-08-23 | 1986-10-28 | Pfizer Inc. | S-6-fluoro-4-aminochroman-4-carboxylic acid derivatives useful as intermediates for sorbinil |
| US4575507A (en) * | 1985-05-29 | 1986-03-11 | Pfizer Inc. | Spiro-imidazolidines as aldose reductase inhibitors and their pharmaceutical use |
| US4952694A (en) * | 1988-07-27 | 1990-08-28 | Pfizer Inc. | Novel resolution process for racemic spiro-hydantoins |
| US5006657A (en) * | 1988-07-27 | 1991-04-09 | Pfizer Inc. | Intermediates in a resolution process for racemic spiro hydantoins |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4177282A (en) * | 1977-05-23 | 1979-12-04 | Pfizer Inc. | Hydantoin therapeutic agents |
-
1983
- 1983-11-03 EP EP83306690A patent/EP0109231B1/de not_active Expired
- 1983-11-03 AT AT83306690T patent/ATE23046T1/de not_active IP Right Cessation
- 1983-11-03 DE DE8383306690T patent/DE3367103D1/de not_active Expired
- 1983-11-08 CA CA000440664A patent/CA1202310A/en not_active Expired
- 1983-11-09 IE IE2618/83A patent/IE56212B1/en not_active IP Right Cessation
- 1983-11-09 HU HU833842A patent/HU188383B/hu not_active IP Right Cessation
- 1983-11-09 PH PH29803A patent/PH20457A/en unknown
- 1983-11-15 RO RO83112566A patent/RO87830A2/ro unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0109231B1 (de) | 1986-10-22 |
| RO87830A2 (ro) | 1985-12-20 |
| EP0109231A1 (de) | 1984-05-23 |
| IE56212B1 (en) | 1991-05-22 |
| CA1202310A (en) | 1986-03-25 |
| IE832618L (en) | 1984-05-10 |
| ATE23046T1 (de) | 1986-11-15 |
| DE3367103D1 (en) | 1986-11-27 |
| HU188383B (en) | 1986-04-28 |
| RO87830B1 (ro) | 1985-12-02 |
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