PH23584A - Piperidine compounds and pharmaceutical compositions containing the same - Google Patents

Piperidine compounds and pharmaceutical compositions containing the same

Info

Publication number: PH23584A
Authority: PH; Philippines
Prior art keywords: piperidine compounds; same; pharmaceutical compositions; compositions containing; chem
Prior art date: 1986-09-08

Application number

PH35635A

Other languages

English (en)

Inventor

Leif Helth Jensen

Per Sauerberg

Frank Waetjen

Jens William Kindtler

Original Assignee

Ferrosan As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-09-08

Filing date

1987-08-06

Publication date

1989-09-11

1986-09-08 Priority claimed from DK426986A external-priority patent/DK426986D0/da

1986-12-12 Priority claimed from DK597186A external-priority patent/DK597186D0/da

1987-08-06 Application filed by Ferrosan As filed Critical Ferrosan As

1989-09-11 Publication of PH23584A publication Critical patent/PH23584A/en

Links

150000003053 piperidines Chemical class 0.000 title abstract 2
239000008194 pharmaceutical composition Substances 0.000 title 1
125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 2
-1 wherein R' is H Chemical group 0.000 abstract 1
125000004209 (C1-C8) alkyl group Chemical group 0.000 abstract 1
208000024827 Alzheimer disease Diseases 0.000 abstract 1
241000124008 Mammalia Species 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
230000003920 cognitive function Effects 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000001559 cyclopropyl group Chemical group [H]C1([H])C([H])([H])C1([H])* 0.000 abstract 1
210000001320 hippocampus Anatomy 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
210000004129 prosencephalon Anatomy 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000001544 thienyl group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Cephalosporin Compounds (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

PH35635A 1986-09-08 1987-08-06 Piperidine compounds and pharmaceutical compositions containing the same PH23584A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DK426986A DK426986D0 (da)	1986-09-08	1986-09-08	Piperidine forbindelser, deres fremstilling og anvendelse
DK597186A DK597186D0 (da)	1986-12-12	1986-12-12	Heterocykliske forbindelser, deres fremstilling og anvendelse

Publications (1)

Publication Number	Publication Date
PH23584A true PH23584A (en)	1989-09-11

Family

ID=26067417

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PH35635A PH23584A (en)	1986-09-08	1987-08-06	Piperidine compounds and pharmaceutical compositions containing the same

Country Status (17)

Country	Link
US (2)	US4837241A (pt)
EP (1)	EP0259621B1 (pt)
JP (1)	JPH0662616B2 (pt)
KR (1)	KR950009366B1 (pt)
AT (1)	ATE82751T1 (pt)
AU (1)	AU603603B2 (pt)
CA (1)	CA1340937C (pt)
DE (1)	DE3782785T2 (pt)
ES (1)	ES2043624T3 (pt)
FI (1)	FI86424C (pt)
GR (1)	GR3007053T3 (pt)
IE (1)	IE62485B1 (pt)
IL (1)	IL83275A (pt)
NO (1)	NO169285C (pt)
NZ (1)	NZ221672A (pt)
PH (1)	PH23584A (pt)
PT (1)	PT85650B (pt)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NZ219646A (en) *	1986-03-27	1990-10-26	Merck Sharp & Dohme	Oxadiazole derivatives of azacyclics for treating cns disorders
GB8714789D0 (en) *	1987-06-24	1987-07-29	Lundbeck & Co As H	Heterocyclic compounds
IE63906B1 (en) *	1987-11-13	1995-06-14	Novo Nordisk As	Azabicyclic compounds and their preparation and use
EP0322034A3 (en) *	1987-12-22	1991-01-02	Merck Sharp & Dohme Ltd.	Methyl tetrahydropyridyl oxadiazoles
IL88846A0 (en) *	1988-01-08	1989-07-31	Merck Sharp & Dohme	Lipophilic oxadiazoles,their preparation and pharmaceutical compositions containing them
DK162892C (da) *	1988-07-04	1992-05-11	Novo Nordisk As	1,2,5,6-tetrahydropyridinforbindelser, deres fremstilling og farmaceutiske praeparater indeholdende disse
US5328925A (en) *	1989-02-22	1994-07-12	Novo Nordisk A/S	Piperidine compounds and their use
US5264444A (en) *	1989-02-22	1993-11-23	Novo Nordisk A/S	Piperidine compounds and use
US5260311A (en) *	1989-02-22	1993-11-09	Novo Nordisk A/S	Piperidine compounds and their use
US5043345A (en) *	1989-02-22	1991-08-27	Novo Nordisk A/S	Piperidine compounds and their preparation and use
EP0459568A3 (en) *	1990-05-31	1992-09-30	Merck Sharp & Dohme Ltd.	Substituted oxadiazoles and thiadiazoles for use in the treatment of glaucoma and novel compounds having such use
MX9100517A (es) *	1990-08-06	1992-04-01	Smith Kline French Lab	Compuestos
DK198490D0 (da) *	1990-08-21	1990-08-21	Novo Nordisk As	Heterocykliske forbindelser, deres fremstilling og anvendelse
WO1992009280A1 (en) *	1990-11-29	1992-06-11	Allergan, Inc.	Use of pyridine derivatives in the treatment of ocular hypertension
US5175166A (en) *	1991-08-27	1992-12-29	The University Of Toledo	Muscarinic agonists
JPH07502529A (ja) *	1991-12-31	1995-03-16	藤沢薬品工業株式会社	アセチルコリンエステラーゼ阻害およびムスカリン様のアゴニスト活性を有するオキサジアゾール誘導体
US5424301A (en) *	1993-02-01	1995-06-13	Warner-Lambert Company	Starch stabilized o-substituted tetrahydropyridine oxime cholinergic agents
DE69418789T2 (de) *	1993-08-05	1999-12-02	Hoechst Marion Roussel, Inc.	2-(Piperidin-4-yl, Pyridin-4-yl und Tetrahydropyridin-4-yl)-benzofuran-7-carbamat Derivate, ihre Herstellung und Verwendung als Acetylcholinesterase Inhibitoren
US5753683A (en) *	1993-08-19	1998-05-19	Novo Nordisk A/S	Antipsychotic method
US5605908A (en) *	1994-10-24	1997-02-25	Eli Lilly And Company	Heterocyclic compounds and their use
US5821370A (en) *	1994-10-24	1998-10-13	Eli Lilly And Company	Heterocyclic compounds and their preparation and use
US5998404A (en)	1994-10-24	1999-12-07	Eli Lilly And Company	Heterocyclic compounds and their use
US5574028A (en) *	1994-10-31	1996-11-12	Eli Lilly And Company	Method for treating anxiety
US5488056A (en) *	1994-10-31	1996-01-30	Eli Lilly And Company	Method for treating anxiety
US5726193A (en) *	1994-10-31	1998-03-10	Eli Lilly And Company	Method for treating anxiety
AU7639598A (en)	1997-05-29	1998-12-30	H. Lundbeck A/S	Treatment of schizophrenia and psychosis
AU2307899A (en) *	1997-12-23	1999-07-12	Alcon Laboratories, Inc.	Muscarinic agents and use thereof to treat glaucoma, myopia and various other conditions
US6107313A (en) *	1998-10-02	2000-08-22	Combichem, Inc.	Dopamine receptor antagonists
US7332508B2 (en)	2002-12-18	2008-02-19	Novo Nordisk A/S	Substituted homopiperidine, piperidine or pyrrolidine derivatives
NZ548693A (en) *	2004-02-18	2010-05-28	Astrazeneca Ab	Polyheterocyclic compounds and their use as metabotropic glutamate receptor antagonists
EP1720874A4 (en) *	2004-02-24	2010-03-03	Bioaxone Therapeutique Inc	4-SUBSTITUTED PIPERIDINE DERIVATIVES
CN101939311A (zh) *	2007-04-24	2011-01-05	索尔瓦药物有限公司	对毒蕈碱受体具有亲和力的杂环类化合物
US8084473B2 (en)	2007-04-24	2011-12-27	Solvay Pharmaceuticals B.V.	Heterocyclic compounds with affinity to muscarinic receptors
US20110294835A1 (en)	2008-05-15	2011-12-01	The Board Of Trustees Of The University Of Illinois	Muscarinic Agonists as Cognitive Enhancers
WO2012149524A1 (en)	2011-04-29	2012-11-01	The University Of Toledo	Muscarinic agonists as enhancers of working memory and cognitive flexibility
US10857157B2 (en)	2015-01-26	2020-12-08	BioAxone BioSciences, Inc.	Treatment of cerebral cavernous malformations and cerebral aneurysms with rho kinase inhibitors
US10106525B2 (en)	2015-01-26	2018-10-23	BioAxone BioSciences, Inc.	Rho kinase inhibitor BA-1049 (R) and active metabolites thereof
US10149856B2 (en)	2015-01-26	2018-12-11	BioAxone BioSciences, Inc.	Treatment of cerebral cavernous malformations and cerebral aneurysms with rho kinase inhibitors
US11198680B2 (en)	2016-12-21	2021-12-14	BioAxone BioSciences, Inc.	Rho kinase inhibitor BA-1049 (R) and active metabolites thereof
US10537567B2 (en)	2017-07-11	2020-01-21	BioAxone BioSciences, Inc.	Kinase inhibitors for treatment of disease
WO2020206410A1 (en) *	2019-04-04	2020-10-08	University Of Maryland, Baltimore	Methods of using muscarinic antagonists in the treatment of depression
EP4216949A4 (en) *	2020-09-28	2024-12-11	Yale University	Selective agonists of 5-ht2a receptor and methods of use

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3966748A (en) *	1975-05-08	1976-06-29	American Cyanamid Company	Para-fluorophenyl-N-heterocyclic substituted butanes
US4518601A (en) *	1982-06-16	1985-05-21	Ciba Geigy Corporation	2-(3-Pyridyl)-1,3,4-oxadiazoles and use thereof in pest control
NZ219646A (en) *	1986-03-27	1990-10-26	Merck Sharp & Dohme	Oxadiazole derivatives of azacyclics for treating cns disorders

1987
- 1987-07-21 IL IL8327587A patent/IL83275A/en unknown
- 1987-08-06 PH PH35635A patent/PH23584A/en unknown
- 1987-08-07 DE DE8787111470T patent/DE3782785T2/de not_active Expired - Fee Related
- 1987-08-07 ES ES87111470T patent/ES2043624T3/es not_active Expired - Lifetime
- 1987-08-07 AT AT87111470T patent/ATE82751T1/de not_active IP Right Cessation
- 1987-08-07 EP EP87111470A patent/EP0259621B1/en not_active Expired - Lifetime
- 1987-08-14 IE IE217387A patent/IE62485B1/en not_active IP Right Cessation
- 1987-08-26 US US07/089,747 patent/US4837241A/en not_active Expired - Lifetime
- 1987-09-02 FI FI873809A patent/FI86424C/fi not_active IP Right Cessation
- 1987-09-03 PT PT85650A patent/PT85650B/pt not_active IP Right Cessation
- 1987-09-04 NZ NZ221672A patent/NZ221672A/xx unknown
- 1987-09-07 NO NO873731A patent/NO169285C/no not_active IP Right Cessation
- 1987-09-08 JP JP62223199A patent/JPH0662616B2/ja not_active Expired - Lifetime
- 1987-09-08 CA CA000546359A patent/CA1340937C/en not_active Expired - Fee Related
- 1987-09-08 KR KR1019870009915A patent/KR950009366B1/ko not_active Expired - Fee Related
- 1987-09-08 AU AU78165/87A patent/AU603603B2/en not_active Ceased
1988
- 1988-08-25 US US07/236,550 patent/US4933353A/en not_active Expired - Fee Related
1993
- 1993-02-11 GR GR930400285T patent/GR3007053T3/el unknown

Also Published As

Publication number	Publication date
JPH0662616B2 (ja)	1994-08-17
NO169285B (no)	1992-02-24
DE3782785D1 (de)	1993-01-07
JPS6377877A (ja)	1988-04-08
ATE82751T1 (de)	1992-12-15
NO169285C (no)	1992-06-03
EP0259621A3 (en)	1988-10-12
FI873809A0 (fi)	1987-09-02
US4933353A (en)	1990-06-12
FI86424B (fi)	1992-05-15
PT85650B (pt)	1990-05-31
KR950009366B1 (ko)	1995-08-21
FI873809A7 (fi)	1988-03-09
IE872173L (en)	1989-03-08
US4837241A (en)	1989-06-06
AU7816587A (en)	1988-03-31
NO873731D0 (no)	1987-09-07
EP0259621B1 (en)	1992-11-25
GR3007053T3 (pt)	1993-07-30
IL83275A (en)	1994-02-27
KR880003939A (ko)	1988-06-01
IE62485B1 (en)	1995-02-08
EP0259621A2 (en)	1988-03-16
NZ221672A (en)	1990-09-26
PT85650A (en)	1987-10-01
DE3782785T2 (de)	1993-04-01
AU603603B2 (en)	1990-11-22
ES2043624T3 (es)	1994-01-01
FI86424C (fi)	1992-08-25
IL83275A0 (en)	1987-12-31
NO873731L (no)	1988-03-09
CA1340937C (en)	2000-03-28

Publication	Publication Date	Title
PH23584A (en)	1989-09-11	Piperidine compounds and pharmaceutical compositions containing the same
GR3003548T3 (pt)	1993-03-16
EP0181001A3 (en)	1989-04-19	Polypeptide, a process for preparing the same, a pharmaceutical composition containing said polypeptide as well as the use thereof
PT86115A (en)	1987-12-01	Therapeutic agents
AR245117A1 (es)	1993-12-30	Procedimiento para la preparacion de 6-metil-3,4-dihidro-1,2,3-oxatiazin-4-on-2,2-dioxido y sus sales asi como su purificacion.
HUT45984A (en)	1988-09-28	Process for production of quinoline-derivatives and of their medically acceptable acid-additioned salts
DE3879429D1 (de)	1993-04-22	Cyclopropanderivate.
DK297485A (da)	1986-03-14	Carbapenemer med kvaternaere heteroarylalkylthio 2-substituenter samt laegemiddel indeholdende saadanne forbindelser
GB8706662D0 (en)	1987-04-23	Anti-arrhythmia agents
DE3371909D1 (en)	1987-07-09	7-alpha-acylthio-15,16-methylene-3-oxo-17-alpha-pregna-1,4-diene-21,17-carbolactones, their preparation and use as medicinal agents
GR82015B (pt)	1984-12-12
IL75430A0 (en)	1985-10-31	Pineapple ketone carbonate derivatives and their use as flavoring agents
DK444087A (da)	1988-03-09	Piperidinforbindelser, deres fremstilling og anvendelse
TW265342B (pt)	1995-12-11