PH23746A - Novel metal chelate resins - Google Patents

Novel metal chelate resins

Info

Publication number
PH23746A
PH23746A PH35505A PH35505A PH23746A PH 23746 A PH23746 A PH 23746A PH 35505 A PH35505 A PH 35505A PH 35505 A PH35505 A PH 35505A PH 23746 A PH23746 A PH 23746A
Authority
PH
Philippines
Prior art keywords
metal chelate
chelate resins
novel metal
complexed
proteins
Prior art date
Application number
PH35505A
Other languages
English (en)
Inventor
Heinz Dr Dobeli
Erich Dr Hochuli
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=4241469&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PH23746(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of PH23746A publication Critical patent/PH23746A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
    • B01D15/3804—Affinity chromatography
    • B01D15/3828—Ligand exchange chromatography, e.g. complexation, chelation or metal interaction chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3244—Non-macromolecular compounds
    • B01J20/3265—Non-macromolecular compounds with an organic functional group containing a metal, e.g. a metal affinity ligand

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Treatment Of Water By Ion Exchange (AREA)
  • Developing Agents For Electrophotography (AREA)
  • Manufacture And Refinement Of Metals (AREA)
  • Polymerisation Methods In General (AREA)
PH35505A 1986-07-10 1987-07-07 Novel metal chelate resins PH23746A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH278286 1986-07-10

Publications (1)

Publication Number Publication Date
PH23746A true PH23746A (en) 1989-11-03

Family

ID=4241469

Family Applications (1)

Application Number Title Priority Date Filing Date
PH35505A PH23746A (en) 1986-07-10 1987-07-07 Novel metal chelate resins

Country Status (13)

Country Link
US (1) US4877830A (fr)
EP (1) EP0253303B1 (fr)
JP (2) JPH0822382B2 (fr)
AT (1) ATE76866T1 (fr)
AU (1) AU596674B2 (fr)
CA (1) CA1304886C (fr)
DE (1) DE3779501D1 (fr)
DK (2) DK172602B1 (fr)
IE (1) IE60468B1 (fr)
IL (1) IL83079A (fr)
NZ (1) NZ220948A (fr)
PH (1) PH23746A (fr)
ZA (1) ZA874860B (fr)

Families Citing this family (76)

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CA1304886C (fr) * 1986-07-10 1992-07-07 Heinz Dobeli Resines chelatant des metaux
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CA1340522C (fr) * 1987-03-10 1999-05-04 Heinz Dobeli Proteins hybrides renfermant des histidines voisines pour une purification amelioree
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US5225534A (en) * 1987-09-08 1993-07-06 Hoffmann-La Roche Inc. Recombinant malarial polypeptides
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EP0486580B1 (fr) * 1989-08-19 1996-11-06 QIAGEN GmbH Procede et dispositif permettant de separer et de detecter les elements d'un melange de substances par electrophorese a gel a gradient de temperature
US5266686A (en) * 1992-09-25 1993-11-30 Pierce Chemical Company Method for isolation and purification of enzyme-antibody conjugates
CA2125467C (fr) * 1993-07-06 2001-02-06 Heinz Dobeli Methode de preparation de polypeptides, proteines ou peptides hydrophobes
SE9303822D0 (sv) * 1993-11-18 1993-11-18 Kabi Pharmacia Ab Method for purification
DE4433980C2 (de) * 1994-09-23 1996-08-22 Boehringer Ingelheim Int Verfahren und Biosensorhit zur Untersuchung der Wechselwirkung von Biomolekülen mittels Oberflächen-Plasma-Resonanz
US5620850A (en) 1994-09-26 1997-04-15 President And Fellows Of Harvard College Molecular recognition at surfaces derivatized with self-assembled monolayers
US6472148B1 (en) 1994-09-26 2002-10-29 President And Fellows Of Harvard College Molecular recognition at surfaces derivatized with self-assembled monolayers
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DE19531173A1 (de) * 1995-08-24 1997-02-27 Boehringer Mannheim Gmbh Verfahren zum Stabilisieren des Gehalts glykierten Proteins einer Probe auf einem Matrixmaterial
DE69730551T2 (de) 1996-04-15 2005-09-01 Givaudan S.A. Hydroxyperoxide Lyasen
US5858724A (en) * 1996-07-16 1999-01-12 Pel-Freez Recombinant rabbit tissue factor
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US7014992B1 (en) 1996-11-05 2006-03-21 Clinical Micro Sensors, Inc. Conductive oligomers attached to electrodes and nucleoside analogs
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AU748903B2 (en) * 1997-06-24 2002-06-13 Proteus Molecular Design Limited Angiotensin derivatives
US6068993A (en) * 1997-07-02 2000-05-30 Biobras Sa Vector for expression of heterologous protein and methods for extracting recombinant protein and for purifying isolated recombinant insulin
US7087148B1 (en) 1998-06-23 2006-08-08 Clinical Micro Sensors, Inc. Binding acceleration techniques for the detection of analytes
CA2277372C (fr) * 1998-07-13 2011-03-15 Tran Quang Minh Resines metalliques a affinite immobilisee
ATE302940T1 (de) 1999-03-04 2005-09-15 Retsch Kurt Gmbh & Co Kg Verfahren und vorrichtung zum aufschluss von biologischem material
US6479300B1 (en) * 1999-03-15 2002-11-12 Millipore Corporation Metal loaded ligand bound membranes for metal ion affinity chromatography
US7312087B2 (en) * 2000-01-11 2007-12-25 Clinical Micro Sensors, Inc. Devices and methods for biochip multiplexing
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JP2001029783A (ja) * 1999-07-13 2001-02-06 Tran Quang Minh 親和性固定化金属樹脂
DK1069131T3 (da) 1999-07-15 2006-06-26 Qiagen Gmbh Fremgangsmåde til at skille partikelformige substrater fra en oplösning med et minimalt tab af partikler
US6379708B1 (en) * 1999-11-20 2002-04-30 Cytologic, Llc Method for enhancing immune responses in mammals
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GB0028879D0 (en) * 2000-11-27 2001-01-10 Prometic Biosciences Ltd Adsorbents and their use
EP1461620A4 (fr) * 2001-12-05 2005-02-02 Large Scale Biology Corp Procede et appareil souples pour flux de production eleve et purification de multiples proteines
AU2003233498A1 (en) * 2002-06-10 2003-12-22 Phynexus, Inc. Biomolecule open channel solid phase extraction systems and methods
US20040224329A1 (en) * 2003-05-08 2004-11-11 Gjerde Douglas T. Three-dimensional solid phase extraction surfaces
US7151167B2 (en) * 2002-06-10 2006-12-19 Phynexus, Inc. Open channel solid phase extraction systems and methods
US7879621B2 (en) * 2003-05-08 2011-02-01 Phynexus, Inc. Open channel solid phase extraction systems and methods
US7122640B2 (en) * 2002-06-10 2006-10-17 Phynexus, Inc. Open channel solid phase extraction systems and methods
US8025873B2 (en) * 2002-06-20 2011-09-27 Paladin Labs, Inc. Chimeric antigens for eliciting an immune response
US8029803B2 (en) 2002-06-20 2011-10-04 Paladin Labs, Inc. Chimeric antigens for eliciting an immune response
AU2003286553A1 (en) * 2002-10-18 2004-05-04 Promega Corporation Methods for separating molecules
US7799526B2 (en) * 2002-11-21 2010-09-21 The University Of North Carolina At Chapel Hill Phosphoprotein detection reagent and methods of making and using the same
SE526214C2 (sv) * 2003-02-28 2005-07-26 Amersham Biosciences Ab Ett sätt att generera metallkelaterande affinitetsligander
SE0301011D0 (sv) * 2003-04-04 2003-04-04 Amersham Biosciences Ab Preparation of a metal chelating separation medium
US20040241721A1 (en) * 2003-05-08 2004-12-02 Gjerde Douglas T. Open channel solid phase extraction systems and methods
SI1626982T1 (sl) * 2003-05-23 2007-10-31 Aplagen Gmbh Kovinski kelatni kompleksi, imobilizirani na trdnih nosilcih, za pripravo peptidov
US8007805B2 (en) * 2003-08-08 2011-08-30 Paladin Labs, Inc. Chimeric antigens for breaking host tolerance to foreign antigens
US20050123932A1 (en) * 2003-12-09 2005-06-09 Mekbib Astatke Nucleic acid-chelating agent conjugates
US7276362B2 (en) * 2004-01-30 2007-10-02 Roche Diagnostics Operations, Inc. Recombinant histidine-tagged inosine monophosphate dehydrogenase polypeptides
DE102004038134B4 (de) 2004-08-05 2013-07-25 Johann Wolfgang Goethe-Universität Frankfurt am Main Multivalente Chelatoren zum Modifizieren und Organisieren von Zielmolekülen, Verfahren zu ihrer Herstellung sowie ihre Verwendung
JP2008520616A (ja) * 2004-11-24 2008-06-19 アプラーゲン ゲゼルシャフト ミット ベシュレンクテル ハフツング 固相ペプチド合成および精製方法
WO2006098671A1 (fr) * 2005-02-14 2006-09-21 Ge Healthcare Bio-Sciences Ab Procede de chromatographie en phase liquide
US7229769B2 (en) * 2005-03-25 2007-06-12 Illumina, Inc. Compositions and methods for detecting protease activity
US20070196833A1 (en) * 2005-04-21 2007-08-23 Gjerde Douglas T Open channel solid phase extraction systems and methods
EA200800109A1 (ru) * 2005-06-23 2008-06-30 Аплаген Гмбх Суправалентные соединения
US20070065514A1 (en) * 2005-09-22 2007-03-22 Howell Mark D Method for enhancing immune responses in mammals
JP2009511024A (ja) * 2005-10-13 2009-03-19 ヴィレックス メディカル コーポレイション 免疫応答を誘導するためのＣ型肝炎ウイルスポリペプチドおよびＦｃフラグメントを含むキメラ抗原
WO2007120999A2 (fr) * 2006-03-06 2007-10-25 Bio-Rad Laboratories, Inc. Chélation de monomères et de polymères
GB0610479D0 (en) * 2006-05-26 2006-07-05 Ge Healthcare Bio Sciences Ab A method for generating metal chelating affinity ligands
EP2164591B1 (fr) * 2007-07-09 2013-05-08 GE Healthcare Bio-Sciences AB Procede pour la preparation d'un agent d'adsorption biomoleculaire
US20090162845A1 (en) * 2007-12-20 2009-06-25 Elazar Rabbani Affinity tag nucleic acid and protein compositions, and processes for using same
NZ589557A (en) * 2008-06-04 2012-08-31 Talecris Biotherapeutics Inc Immobilised streptokinase, method and kit for preparing plasmin
EP2192410B1 (fr) 2008-11-26 2012-07-11 Corning Incorporated Capture par affinité de nanoparticules pour système de détection indépendant des étiquettes
HUE025670T2 (en) 2009-03-03 2016-04-28 Grifols Therapeutics Inc A method for producing plasminogen
JP2013507124A (ja) * 2009-10-09 2013-03-04 アナフォア インコーポレイテッド Ｉｌ−２３ｒを結合するポリペプチド
EP2362220A1 (fr) 2010-02-25 2011-08-31 Corning Incorporated Hydrogel d'affinité et procédés de détection indépendants de l'étiquette correspondants
HU230585B1 (hu) 2012-05-30 2017-01-30 Budapesti Műszaki és Gazdaságtudományi Egyetem Fehérjék megkötésére és elválasztására alkalmas lantanida fémionokkal komplexált hordozók
JP2014113108A (ja) * 2012-12-11 2014-06-26 Tokyo Medical Univ タンパク質の可溶化活性を有する多量体タンパク質およびその用途
CA3121103C (fr) 2018-11-28 2023-10-10 Cube Biotech Gmbh Materiau chelateur en phase solide, son procede de production et son utilisation pour la purification de proteines
CN109535274B (zh) * 2018-11-30 2021-02-19 淮阴工学院 一种蒲菜多糖脱蛋白脱色的方法
EP4288411B1 (fr) 2021-02-02 2025-11-05 Cube Biotech GmbH Chélateur soluble pour le ciblage de protéines recombinantes
CN113150194A (zh) * 2021-02-24 2021-07-23 广东昊邦医药健康有限责任公司 金属螯合树脂及其制备方法、应用
CN116874642B (zh) * 2023-06-28 2026-05-12 百林科(兰州)新材料有限公司 一种金属螯合层析介质及其制备方法
CN117339580B (zh) * 2023-12-05 2024-04-02 凯莱英生命科学技术(天津)有限公司 螯合载体、其制备方法及应用

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US4530963A (en) * 1982-08-20 1985-07-23 Devoe-Holbein International, N.V. Insoluble chelating compositions
CA1304886C (fr) * 1986-07-10 1992-07-07 Heinz Dobeli Resines chelatant des metaux

Also Published As

Publication number Publication date
US4877830A (en) 1989-10-31
EP0253303A2 (fr) 1988-01-20
DK172891B1 (da) 1999-09-13
IL83079A0 (en) 1987-12-31
ZA874860B (en) 1988-01-11
NZ220948A (en) 1990-07-26
JPH0822382B2 (ja) 1996-03-06
IL83079A (en) 1991-11-21
DK172602B1 (da) 1999-02-22
AU7524587A (en) 1988-01-14
EP0253303B1 (fr) 1992-06-03
CA1304886C (fr) 1992-07-07
IE60468B1 (en) 1994-07-13
IE871842L (en) 1988-01-10
JP2562571B2 (ja) 1996-12-11
DE3779501D1 (de) 1992-07-09
JPS6344947A (ja) 1988-02-25
DK149397A (da) 1997-12-19
JPH0899944A (ja) 1996-04-16
DK285187D0 (da) 1987-06-03
ATE76866T1 (de) 1992-06-15
DK285187A (da) 1988-01-11
AU596674B2 (en) 1990-05-10
EP0253303A3 (en) 1989-05-24

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