PH26229A - Azithromycin and derivatives as antiprotozoal agents - Google Patents

Azithromycin and derivatives as antiprotozoal agents Download PDF

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Publication number
PH26229A
PH26229A PH37527A PH37527A PH26229A PH 26229 A PH26229 A PH 26229A PH 37527 A PH37527 A PH 37527A PH 37527 A PH37527 A PH 37527A PH 26229 A PH26229 A PH 26229A
Authority
PH
Philippines
Prior art keywords
azithromycin
deoxy
epi
amino
comprises administering
Prior art date
Application number
PH37527A
Other languages
English (en)
Inventor
Jack Samuel Remington
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of PH26229A publication Critical patent/PH26229A/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
PH37527A 1987-09-10 1988-09-09 Azithromycin and derivatives as antiprotozoal agents PH26229A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1987/002317 WO1989002271A1 (fr) 1987-09-10 1987-09-10 Azithromycine et derives utilises comme agents anti-protozoaires

Publications (1)

Publication Number Publication Date
PH26229A true PH26229A (en) 1992-04-01

Family

ID=22202554

Family Applications (1)

Application Number Title Priority Date Filing Date
PH37527A PH26229A (en) 1987-09-10 1988-09-09 Azithromycin and derivatives as antiprotozoal agents

Country Status (18)

Country Link
US (1) US4963531A (fr)
EP (1) EP0307128B1 (fr)
JP (1) JPH0667847B2 (fr)
KR (1) KR930011996B1 (fr)
AT (1) ATE74508T1 (fr)
AU (1) AU596029B2 (fr)
CA (1) CA1334574C (fr)
DE (1) DE3869880D1 (fr)
DK (1) DK175544B1 (fr)
HU (1) HUT47553A (fr)
IE (1) IE61507B1 (fr)
IL (1) IL87698A (fr)
MY (1) MY103388A (fr)
NZ (1) NZ226112A (fr)
PH (1) PH26229A (fr)
PT (1) PT88448B (fr)
WO (1) WO1989002271A1 (fr)
ZA (1) ZA886727B (fr)

Families Citing this family (57)

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RO107257B1 (ro) 1987-07-09 1993-10-30 Pfizer Procedeu de obtinere a unui dihidrat de azitromicina, cristalin
SI9011409A (en) * 1990-07-18 1995-10-31 Pliva Pharm & Chem Works O-methyl azitromycin derivates, methods and intermediates for their preparation and methods for preparation of pharmaceuticals products which comprise them
US5912331A (en) * 1991-03-15 1999-06-15 Merck & Co., Inc. Process for the preparation of 9-deoxo-9(Z)-hydroxyiminoerythromycin A
US5985844A (en) * 1992-03-26 1999-11-16 Merck & Co., Inc. Homoerythromycin A derivatives modified at the 4"-and 8A-positions
US5189159A (en) * 1992-04-02 1993-02-23 Merck & Co., Inc. 8a-AZA-8a-homoerythromycin cyclic iminoethers
US5215980A (en) * 1992-01-17 1993-06-01 Merck & Co., Inc. 10-AZA-9-deoxo-11-deoxy-erythromycin A and derivatives thereof
TW271400B (fr) * 1992-07-30 1996-03-01 Pfizer
US5210235A (en) * 1992-08-26 1993-05-11 Merck & Co., Inc. Methods of elaborating erythromycin fragments into amine-containing fragments of azalide antibiotics
US5332807A (en) * 1993-04-14 1994-07-26 Merck & Co., Inc. Process of producing 8A- and 9A-azalide antibiotics
US5529994A (en) * 1993-05-05 1996-06-25 Palo Alto Medical Foundation Treatment for toxoplasmosis
DE69400631T2 (de) * 1993-05-05 1997-02-27 Palo Alto Medical Foundation, Palo Alto, Calif. Verwendung von rifamycinderivaten zur herstellung eines arzneimittels zur behandlung der toxoplasmose
CA2189001A1 (fr) * 1994-04-26 1995-11-02 Nobuhiro Narita Composition medicinale servant de medicament contre le cancer bronchopulmonaire "non a petites cellules"
AU744318B2 (en) * 1994-04-29 2002-02-21 Pfizer Inc. Method of administering azithromycin
US5605889A (en) * 1994-04-29 1997-02-25 Pfizer Inc. Method of administering azithromycin
JP2977907B2 (ja) * 1994-05-06 1999-11-15 ファイザー・インコーポレーテッド アジスロマイシンの放出調節された剤形
US20030212123A1 (en) * 1997-05-05 2003-11-13 Pfizer Inc. COX-2 selective carprofen for treating pain and inflammation in dogs
US6407074B1 (en) * 1997-06-11 2002-06-18 Pfizer Inc C-4″-substituted macrolide derivatives
JP2003512290A (ja) * 1997-09-10 2003-04-02 メルク エンド カムパニー インコーポレーテッド 家畜抗菌剤としての８ａ−アザライド
JP2001520234A (ja) * 1997-10-16 2001-10-30 プリバ フアルマセウトスカ インダストリヤ デイオニツコ ドルストヴオ ９ａ−アザリド類から誘導される新規３，６−ヘミケタール類
AU768219B2 (en) * 1998-11-30 2003-12-04 Teva Pharmaceutical Industries Ltd. Ethanolate of azithromycin, process for manufacture, and pharmaceutical compositions thereof
US6555139B2 (en) 1999-06-28 2003-04-29 Wockhardt Europe Limited Preparation of micron-size pharmaceutical particles by microfluidization
IT1313610B1 (it) * 1999-08-09 2002-09-09 S I F I Societa Ind Farmaceuti Processo per la preparazione di formulazioni acquose per uso oftalmico
US6608033B1 (en) 1999-08-27 2003-08-19 Pfizer Inc. Treatment or prevention of coccidiosis
WO2001049697A1 (fr) * 2000-01-04 2001-07-12 Teva Pharmaceutical Industries Ltd. Procede de preparation d'azithromycine dihydratee
WO2002007736A1 (fr) * 2000-07-24 2002-01-31 Cadila Pharmaceuticals Limited Fabrication d'une composition pharmaceutique liquide limpide d'azithromycine
WO2002010144A1 (fr) 2000-07-25 2002-02-07 Laboratorio Silanes, S.A. De C.V. Procede permettant de preparer en une seule etape de la 7,16-dioxa-2-aza-10-o-cladinosyl-12-o-desosaminyl-4,5-dihydroxy-6-ethyl-3,5,9,11,13,15-hexamethylbicyclo[11.2.1]hexa-deca-1(2)-en-8-one et permettant d'obtenir une nouvelle forme de 9-desoxo-9a-aza-9a-methyl-9a-homoerythromycine a
WO2002009640A2 (fr) * 2000-08-01 2002-02-07 Shiva Prasad Singh Élaboration d'azithromycine anhydre
AU2001280000A1 (en) 2000-08-23 2002-03-04 Jaweed Mukarram, Siddiqui Mohammed Process for preparation of anhydrous azithromycin
CA2429639C (fr) * 2000-11-27 2009-07-14 Biochemie S.A. Monohydrate d'azithromycine stable
KR100491183B1 (ko) 2001-03-21 2005-05-25 한미약품 주식회사 아지트로마이신의 제조방법 및 이 방법에 사용되는9-데옥소-9에이-아자-9에이-호모에리트로마이신 에이의결정성 수화물
US6861413B2 (en) * 2001-05-22 2005-03-01 Pfizer Inc. Stable non-dihydrate azithromycin oral suspensions
EP1671978A1 (fr) 2001-05-22 2006-06-21 Pfizer Products Inc. Nouvelle forme cristalline de l'azithromycine
PL367091A1 (en) * 2001-05-22 2005-02-21 Pfizer Products Inc. Crystal forms of azithromycin
SK1012004A3 (sk) * 2001-08-21 2005-04-01 Pfizer Products Inc. Použitie azitromycínu na výrobu liečiva na liečenie respiračných infekcií u človeka
DE60232005D1 (de) * 2001-10-18 2009-05-28 Teva Pharma Stabilisierte azithromycin-zusammensetzungen
US20080149521A9 (en) * 2001-10-18 2008-06-26 Michael Pesachovich Methods of stabilizing azithromycin
MXPA04003027A (es) * 2001-12-21 2004-07-05 Pfizer Prod Inc Metodos para granulacion humeda de azitromicina.
EP1455758A1 (fr) * 2001-12-21 2004-09-15 Pfizer Products Inc. Formulations d'azithromycine directement compressibles
RU2212242C1 (ru) * 2001-12-24 2003-09-20 Закрытое акционерное общество "Брынцалов-А" Антибиотик сумазид
EP1478347A1 (fr) * 2002-02-01 2004-11-24 Pfizer Products Inc. Preparation d'azithromycine en granulat sec
ES2220229B1 (es) * 2003-05-29 2005-10-16 Quimica Sintetica, S.A. Sales de adicion de azitromicina y acido citrico y procedimiento para su obtencion.
US20050013835A1 (en) * 2003-07-15 2005-01-20 Pfizer Inc. Stable non-dihydrate azithromycin oral suspensions
CA2547597A1 (fr) * 2003-12-04 2005-06-16 Pfizer Products Inc. Compositions multiparticulaires a stabilite amelioree
MXPA06005913A (es) * 2003-12-04 2006-06-27 Pfizer Prod Inc Formas de dosificacion de multiparticulas de azitromicina por procedimientos basados en liquidos.
BRPI0417348A (pt) 2003-12-04 2007-03-13 Pfizer Prod Inc processo de gelatinização por spray com utilização de uma extrusora para preparação de composições de droga cristalina multiparticulada contendo preferencialmente um poloxámero e um glicerìdeo
RU2331410C2 (ru) 2003-12-04 2008-08-20 Пфайзер Продактс Инк. Способ получения фармацевтических мультичастиц
WO2005053652A1 (fr) 2003-12-04 2005-06-16 Pfizer Products Inc. Compositions medicamenteuses cristallines multiparticulaires contenant un poloxamere et un glyceride
WO2005053639A2 (fr) * 2003-12-04 2005-06-16 Pfizer Products Inc. Formes multiparticulaires a liberation controlee produites avec des optimiseurs de dissolution
US6984403B2 (en) * 2003-12-04 2006-01-10 Pfizer Inc. Azithromycin dosage forms with reduced side effects
KR20060109481A (ko) * 2003-12-04 2006-10-20 화이자 프로덕츠 인코포레이티드 바람직하게는 폴록사머와 글리세라이드를 함유하는다미립자 아지트로마이신 조성물의 제조를 위해 압출기를사용하는 분무응결 방법
CN1295719C (zh) * 2003-12-30 2007-01-17 郑玉庆 远程智能型变压器
US7468428B2 (en) 2004-03-17 2008-12-23 App Pharmaceuticals, Llc Lyophilized azithromycin formulation
WO2006115494A1 (fr) * 2005-04-26 2006-11-02 American Pharmaceutical Partners, Inc. Formulation d’azithromycine lyophilisee
US20060046970A1 (en) * 2004-08-31 2006-03-02 Insite Vision Incorporated Topical otic compositions and methods of topical treatment of prevention of otic infections
US20060198895A1 (en) * 2005-03-07 2006-09-07 Kotliar Eleonora M Azithromycin powder for oral suspension compositions
CN100427499C (zh) * 2005-12-20 2008-10-22 山东诚创医药技术开发有限公司 一种阿奇霉素的可溶性盐及其制备方法
WO2013088274A1 (fr) 2011-12-14 2013-06-20 Wockhardt Limited Composition d'azithromycine amorphe anhydre dépourvue de dihydrate d'azithromycine

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI8110592A8 (en) * 1981-03-06 1996-06-30 Pliva Pharm & Chem Works Process for preparing of n-methyl-11-aza-10-deoxo-10-dihydroerythromycine a and derivatives thereof
US4474768A (en) * 1982-07-19 1984-10-02 Pfizer Inc. N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor
ZA835204B (en) * 1982-07-19 1985-02-27 Pfizer N-methyl 11-aza-10-deoxo-10-dihydroerythromycin a,intermediates therefor and processes for their preparation
PH19293A (en) * 1982-11-15 1986-03-04 Pfizer Epimeric azahomoerythromycin,pharmaceutical composition containing the same and method of use thereof
US4526889A (en) * 1982-11-15 1985-07-02 Pfizer Inc. Epimeric azahomoerythromycin A derivative, intermediates and method of use
US4512982A (en) * 1984-04-13 1985-04-23 Pfizer Inc. 9α-Aza-9α-homoerythromycin compounds, pharmaceutical composition and therapeutic method
AU8280087A (en) * 1987-09-10 1989-04-17 Pfizer Inc. Azithromycin and derivatives as antiprotozoal agents

Also Published As

Publication number Publication date
AU2206188A (en) 1989-05-11
EP0307128A3 (en) 1990-07-04
DE3869880D1 (de) 1992-05-14
IE61507B1 (en) 1994-11-02
MY103388A (en) 1993-06-30
EP0307128A2 (fr) 1989-03-15
IE882762L (en) 1989-03-10
ZA886727B (en) 1990-04-25
KR930011996B1 (ko) 1993-12-23
WO1989002271A1 (fr) 1989-03-23
ATE74508T1 (de) 1992-04-15
DK502888A (da) 1989-03-13
NZ226112A (en) 1997-03-24
DK175544B1 (da) 2004-11-29
IL87698A (en) 1992-12-01
EP0307128B1 (fr) 1992-04-08
PT88448B (pt) 1992-10-30
AU596029B2 (en) 1990-04-12
US4963531A (en) 1990-10-16
HUT47553A (en) 1989-03-28
CA1334574C (fr) 1995-02-28
JPH0667847B2 (ja) 1994-08-31
KR890004709A (ko) 1989-05-09
IL87698A0 (en) 1989-02-28
PT88448A (pt) 1989-07-31
DK502888D0 (da) 1988-09-09
JPH0283326A (ja) 1990-03-23

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