PH27364A - Antibacterial 5-alkylquino-lonecarboxylic acids - Google Patents

Antibacterial 5-alkylquino-lonecarboxylic acids

Info

Publication number
PH27364A
PH27364A PH40321A PH40321A PH27364A PH 27364 A PH27364 A PH 27364A PH 40321 A PH40321 A PH 40321A PH 40321 A PH40321 A PH 40321A PH 27364 A PH27364 A PH 27364A
Authority
PH
Philippines
Prior art keywords
lonecarboxylic
alkylquino
antibacterial
acids
lonecarboxylic acids
Prior art date
Application number
PH40321A
Inventor
Michael Schriewer
Klaus Grohe
Andreas Krebs
Ingo Haller
Karl Georg Metzger
Rainer Endermann
Uwe Petersen
Thomas Schenke
Hans-Joachim Zeiller
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of PH27364A publication Critical patent/PH27364A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
PH40321A 1989-04-03 1990-04-03 Antibacterial 5-alkylquino-lonecarboxylic acids PH27364A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3910663A DE3910663A1 (en) 1989-04-03 1989-04-03 5-ALKYLCHINOLON CARBONIC ACIDS

Publications (1)

Publication Number Publication Date
PH27364A true PH27364A (en) 1993-06-21

Family

ID=6377683

Family Applications (1)

Application Number Title Priority Date Filing Date
PH40321A PH27364A (en) 1989-04-03 1990-04-03 Antibacterial 5-alkylquino-lonecarboxylic acids

Country Status (16)

Country Link
EP (1) EP0391132A1 (en)
JP (1) JP3046035B2 (en)
KR (1) KR0156245B1 (en)
CN (1) CN1035945C (en)
AU (1) AU638005B2 (en)
CA (1) CA2013449C (en)
DD (1) DD298400A5 (en)
DE (1) DE3910663A1 (en)
FI (1) FI901615A7 (en)
HU (2) HUT58056A (en)
IL (1) IL93954A0 (en)
NO (1) NO173547C (en)
NZ (1) NZ233142A (en)
PH (1) PH27364A (en)
PT (1) PT93639A (en)
ZA (1) ZA902510B (en)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4920120A (en) * 1988-01-25 1990-04-24 Warner-Lambert Company Antibacterial agents
MY105136A (en) * 1988-04-27 1994-08-30 Daiichi Seiyaku Co Optically active pyridonecarboxylic acid derivatives.
DD285601A5 (en) * 1988-07-15 1990-12-19 Bayer Ag,De PROCESS FOR PREPARING 7- (1-PYRROLIDINYL) -3-CHINOLONE AND NAPHTHYRIDONE CARBOXYLIC ACID DERIVATIVES
DE59009705D1 (en) * 1989-04-17 1995-11-02 Bayer Ag Process for the preparation of 2,7-diazabicyclo (3.3.0) octanes.
US5177210A (en) * 1989-04-17 1993-01-05 Bayer Aktiengesellschaft Preparation of 2,7-diazabicyclo(3.3.0)octanes
US5241076A (en) * 1989-04-17 1993-08-31 Bayer Aktiengesellschaft 1,4-diazatricyclo [6.3.0.0]undecanes
EP0593766B1 (en) * 1991-05-28 2000-09-06 Daiichi Pharmaceutical Co., Ltd. Pyridonecarboxylic acid derivative
DE4120646A1 (en) * 1991-06-22 1992-12-24 Bayer Ag 7-ISOINDOLINYL-CHINOLONE AND NAPHTHYRIDONE CARBONIC ACID DERIVATIVES
TW209865B (en) * 1992-01-10 1993-07-21 Bayer Ag
KR960003611B1 (en) * 1992-07-23 1996-03-20 재단법인 한국화학연구소 New diazabicyclo alkene derivatives and the preparation process thereof
DE4234078A1 (en) * 1992-10-09 1994-04-14 Bayer Ag Quinolonecarboxylic acids
DE4234330A1 (en) * 1992-10-12 1994-04-14 Bayer Ag Quinolonecarboxylic acids
JP3268098B2 (en) * 1992-12-25 2002-03-25 第一製薬株式会社 Bicyclic cyclic amine derivative
AU4272793A (en) * 1993-04-24 1994-11-21 Korea Research Institute Of Chemical Technology Novel quinolone carboxylic acid derivatives and process for preparing the same
DE4329600A1 (en) * 1993-09-02 1995-03-09 Bayer Ag Pyrido [1,2,3-d, e] [1,3,4] benzoxadiazine derivatives
DE4339134A1 (en) * 1993-11-16 1995-05-18 Bayer Ag 1- (2-fluorocyclopropyl) quinolone and naphthyridonecarboxylic acid derivatives
DE4408212A1 (en) * 1994-03-11 1995-09-14 Bayer Ag 5-vinyl and 5-ethynyl quinolone and naphthyridone carboxylic acids
DE19546249A1 (en) * 1995-12-12 1997-06-19 Bayer Ag New crystal modification of 1-cyclopropyl-7 - ([S, S] -2,8-diazabicyclo [4,3,0] non-8-yl) -6-fluoro-1,4-dihydro-8-methoxy-4 -oxo-3-quinoline carboxylic acid hydrochloride (CDCH), process for its preparation and pharmaceutical preparations containing it
ATE228130T1 (en) * 1996-02-23 2002-12-15 Bayer Ag OPTIONALLY SUBSTITUTED 8-CYAN-1-CYCLOPROPYL-7-(2,8-DIAZABICYCLO-4.3.0)-NONAN-8-YL)-6-FLUORO-1,4-DIHYDRO-4-OXO-3-HINOLINECARBONIC ACIDS AND THEIR DERIVATIVES
DE19633805A1 (en) * 1996-02-23 1997-08-28 Bayer Ag Optionally substituted 8-cyano-l-cyclopropyl-7- (2,8-diazabicyclo- [4.3.0] -nonan-8-yl) -6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids and their derivatives
DE19652239A1 (en) 1996-12-16 1998-06-18 Bayer Ag Use of 7- (2-oxa-5,8-diazabicyclo [4.3.0] non-8-yl) -quinolone and naphthyridonecarboxylic acid derivatives for the therapy of Helicobacter pylori infections and the associated gastroduodenal diseases
DE19854356A1 (en) * 1998-11-25 2000-05-31 Bayer Ag Crystal modification A of 8-cyan-1-cyclopropyl-7- (1S, 6S-2,8-diazabicyclo- / 4.3.0 / nonan-8-yl) -6-fluoro-1,4-dihydro-4-oxo 3-quinoline carboxylic acid
DE19854355A1 (en) * 1998-11-25 2000-05-31 Bayer Ag Crystal modification B of 8-cyan-1-cyclopropyl-7- (1S, 6S-2,8-diazabicyclo- / 4.3.O / nonan-8-yl) -6-fluoro-1,4-dihydro-4-oxo 3-quinoline carboxylic acid
DE19854357A1 (en) * 1998-11-25 2000-05-31 Bayer Ag Semi-hydrochloride of 8-cyano-1-cyclopropyl-7- (1S, 6S-2,8-diazabicyclo / 4.3.0 / -nonan-8-yl) -6-fluoro-1,4-dihydro-4-oxo -3-quinoline carboxylic acid
JP2006504690A (en) * 2002-09-10 2006-02-09 ファイザー・プロダクツ・インク Diazabicyclic compounds useful for the treatment of CNS and other disorders
SI1666477T1 (en) 2003-09-10 2013-10-30 Kyorin Pharmaceutical Co., Ltd. 7-(4-substituted 3- cyclopropylaminomethyl-1- pyrrolidinyl) q uinolonecarboxylic acid derivative
US8222407B2 (en) 2007-05-24 2012-07-17 Kyorin Pharmaceutical Co., Ltd. Mutilin derivative having heterocyclic aromatic ring carboxylic acid structure in substituent at 14-position

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3522405A1 (en) * 1985-06-22 1987-01-02 Bayer Ag 1,8-BRIDGED 4-CHINOLON-3-CARBONIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND THE MEDICINAL PRODUCTS CONTAINING THE SAME AND THE USE THEREOF FOR THE PRODUCTION OF MEDICINAL PRODUCTS
DE3543513A1 (en) * 1985-12-10 1987-06-11 Bayer Ag ENANTIOMER-PURE 1,8-BRIDGED 4-CHINOLON-3-CARBONIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND THE MEDICINAL PRODUCTS CONTAINING THEM AND THEIR USE FOR THE PRODUCTION OF MEDICINAL PRODUCTS
DE3601567A1 (en) * 1986-01-21 1987-07-23 Bayer Ag 7- (AZABICYCLOALKYL) -CHINOLONCARBONIC ACID AND -NAPHTHYRIDON-CARBONIC ACID DERIVATIVES
DE3702393A1 (en) * 1987-01-28 1988-08-11 Bayer Ag 8-CYANO-1-CYCLOPROPYL-1,4-DIHYDRO-4-OXO- 3-CHINOLINE CARBONIC ACIDS, METHOD FOR THEIR PRODUCTION AND ANTIBACTERIAL AGENTS CONTAINING THEM
US5591744A (en) * 1987-04-16 1997-01-07 Otsuka Pharmaceutical Company, Limited Benzoheterocyclic compounds
US4920120A (en) * 1988-01-25 1990-04-24 Warner-Lambert Company Antibacterial agents

Also Published As

Publication number Publication date
CA2013449C (en) 2001-01-02
FI901615A7 (en) 1990-10-04
AU638005B2 (en) 1993-06-17
KR900016186A (en) 1990-11-12
NZ233142A (en) 1992-09-25
PT93639A (en) 1990-11-20
AU5231790A (en) 1990-10-04
EP0391132A1 (en) 1990-10-10
NO901274D0 (en) 1990-03-20
JP3046035B2 (en) 2000-05-29
FI901615A0 (en) 1990-03-30
ZA902510B (en) 1991-01-30
HUT58056A (en) 1992-01-28
HU204811B (en) 1992-02-28
KR0156245B1 (en) 1998-11-16
NO173547C (en) 1993-12-29
IL93954A0 (en) 1990-12-23
HUT56563A (en) 1991-09-30
HU902055D0 (en) 1990-08-28
HU912263D0 (en) 1991-12-30
DE3910663A1 (en) 1990-10-04
NO173547B (en) 1993-09-20
CA2013449A1 (en) 1990-10-03
JPH02289583A (en) 1990-11-29
CN1046162A (en) 1990-10-17
DD298400A5 (en) 1992-02-20
CN1035945C (en) 1997-09-24
NO901274L (en) 1990-10-04

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