PH29958A - Iodinated aryloxy esters - Google Patents

Iodinated aryloxy esters

Info

Publication number
PH29958A
PH29958A PH46915A PH46915A PH29958A PH 29958 A PH29958 A PH 29958A PH 46915 A PH46915 A PH 46915A PH 46915 A PH46915 A PH 46915A PH 29958 A PH29958 A PH 29958A
Authority
PH
Philippines
Prior art keywords
aryloxy
alkyl
aralkyl
cycloalkyl
alkoxy
Prior art date
Application number
PH46915A
Other languages
English (en)
Inventor
Edward R Bacon
Sol J Dau
Paul P Spara
Original Assignee
Sterling Winthrop Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Winthrop Inc filed Critical Sterling Winthrop Inc
Publication of PH29958A publication Critical patent/PH29958A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/04X-ray contrast preparations
    • A61K49/0433X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/01Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/45Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C07C233/53Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
    • C07C233/54Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of a saturated carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/88Carboxylic acid amides having nitrogen atoms of carboxamide groups bound to an acyclic carbon atom and to a carbon atom of a six-membered aromatic ring wherein at least one ortho-hydrogen atom has been replaced
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/90Carboxylic acid amides having nitrogen atoms of carboxamide groups further acylated
    • C07C233/91Carboxylic acid amides having nitrogen atoms of carboxamide groups further acylated with carbon atoms of the carboxamide groups bound to acyclic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
PH46915A 1992-12-16 1993-09-21 Iodinated aryloxy esters PH29958A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/990,987 US5322679A (en) 1992-12-16 1992-12-16 Iodinated aroyloxy esters

Publications (1)

Publication Number Publication Date
PH29958A true PH29958A (en) 1996-09-16

Family

ID=25536725

Family Applications (1)

Application Number Title Priority Date Filing Date
PH46915A PH29958A (en) 1992-12-16 1993-09-21 Iodinated aryloxy esters

Country Status (16)

Country Link
US (2) US5322679A (de)
EP (1) EP0603922B1 (de)
JP (1) JPH06199754A (de)
KR (1) KR940014293A (de)
AT (1) ATE155772T1 (de)
AU (1) AU666220B2 (de)
CA (1) CA2106413A1 (de)
CZ (1) CZ274893A3 (de)
DE (1) DE69312446D1 (de)
FI (1) FI935308A7 (de)
HU (1) HUT65772A (de)
IL (1) IL107796A0 (de)
NO (1) NO934333L (de)
NZ (1) NZ248673A (de)
PH (1) PH29958A (de)
SK (1) SK142593A3 (de)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5330739A (en) * 1992-12-04 1994-07-19 Sterling Winthrop Inc. Iodinated benzoyl acetals and ketals for x-ray imaging
US5322679A (en) * 1992-12-16 1994-06-21 Sterling Winthrop Inc. Iodinated aroyloxy esters
US5346688A (en) * 1992-12-16 1994-09-13 Sterling Winthrop Inc. Iodinated wetting agents
US5316755A (en) * 1993-02-02 1994-05-31 Sterling Winthrop Inc. Compositions of iodophenoxy alkanes and iodophenyl ethers for visualization of the gastrointestinal tract
NO940115D0 (no) * 1994-01-13 1994-01-13 Nycomed Imaging As Kontrastmidler for roentgen- og magnettomografisk avbildning
CA2184089A1 (en) * 1994-02-25 1995-08-31 Carl R. Illig X-ray contrast compositions containing cellulose derivatives
US5488133A (en) * 1994-03-10 1996-01-30 Eastman Kodak Company Iodinated aroyloxy ketones
JPH09512029A (ja) * 1994-04-21 1997-12-02 ニコメド イマギング アクスイェ セルスカプ 薬理学的に許容される粘土を含むx線造影組成物
NL9400762A (nl) * 1994-05-09 1995-12-01 T G Wiersma Vaginaal contrastmiddel voor röntgendiagnostisch onderzoek en werkwijze voor de bereiding ervan.
US5525328A (en) * 1994-06-24 1996-06-11 Nanosystems L.L.C. Nanoparticulate diagnostic diatrizoxy ester X-ray contrast agents for blood pool and lymphatic system imaging
JPH10502083A (ja) * 1994-06-24 1998-02-24 ナノシステムズ エル エル シー 医療診断用の画像形成のためのx線造影剤として有用な2,4,6−トリヨード−5−置換アミノ−イソフタル酸エステル
FI965096A7 (fi) * 1994-06-24 1996-12-18 Nanosystems Llc Alfa-(sykloalkyyli-, aryyli- ja aralkyyli)substituoidut polyjodatut ar oyylioksiyhdisteet
JP4484247B2 (ja) * 1995-02-24 2010-06-16 エラン ファーマ インターナショナル,リミティド ナノ粒子分散体を含有するエアロゾル
US5643552A (en) * 1995-03-09 1997-07-01 Nanosystems L.L.C. Nanoparticulate diagnostic mixed carbonic anhydrides as x-ray contrast agents for blood pool and lymphatic system imaging
US5521218A (en) * 1995-05-15 1996-05-28 Nanosystems L.L.C. Nanoparticulate iodipamide derivatives for use as x-ray contrast agents
US5573750A (en) * 1995-05-22 1996-11-12 Nanosystems L.L.C. Diagnostic imaging x-ray contrast agents
US5834025A (en) 1995-09-29 1998-11-10 Nanosystems L.L.C. Reduction of intravenously administered nanoparticulate-formulation-induced adverse physiological reactions
UA72189C2 (uk) 1997-11-17 2005-02-15 Янссен Фармацевтика Н.В. Фармацевтична композиція, що містить водну суспензію субмікронних ефірів 9-гідроксирисперидон жирних кислот
US6375986B1 (en) 2000-09-21 2002-04-23 Elan Pharma International Ltd. Solid dose nanoparticulate compositions comprising a synergistic combination of a polymeric surface stabilizer and dioctyl sodium sulfosuccinate
US6969529B2 (en) 2000-09-21 2005-11-29 Elan Pharma International Ltd. Nanoparticulate compositions comprising copolymers of vinyl pyrrolidone and vinyl acetate as surface stabilizers
US7521068B2 (en) 1998-11-12 2009-04-21 Elan Pharma International Ltd. Dry powder aerosols of nanoparticulate drugs
US20040141925A1 (en) * 1998-11-12 2004-07-22 Elan Pharma International Ltd. Novel triamcinolone compositions
US7998507B2 (en) * 2000-09-21 2011-08-16 Elan Pharma International Ltd. Nanoparticulate compositions of mitogen-activated protein (MAP) kinase inhibitors
US7198795B2 (en) * 2000-09-21 2007-04-03 Elan Pharma International Ltd. In vitro methods for evaluating the in vivo effectiveness of dosage forms of microparticulate of nanoparticulate active agent compositions
CA2465793A1 (en) * 2001-11-07 2003-05-15 Taffy Williams Methods for vascular imaging using nanoparticulate contrast agents
US20030129242A1 (en) * 2002-01-04 2003-07-10 Bosch H. William Sterile filtered nanoparticulate formulations of budesonide and beclomethasone having tyloxapol as a surface stabilizer
WO2003082213A2 (en) * 2002-03-28 2003-10-09 Imcor Pharmaceutical Company Compositions and methods for delivering pharmaceutically active agents using nanoparticulates
EP1830902A2 (de) * 2004-12-30 2007-09-12 Cinvention Ag Kombination aus einem mittel, das ein signal abgibt, implantatmaterial und arzeimittel
CA2591942A1 (en) * 2005-01-13 2006-07-20 Cinvention Ag Composite materials containing carbon nanoparticles
WO2006077256A1 (en) * 2005-01-24 2006-07-27 Cinvention Ag Metal containing composite materials
EA200702019A1 (ru) * 2005-03-18 2008-02-28 Синвеншен Аг Способ изготовления пористых спечённых металлсодержащих материалов
US20090081297A1 (en) * 2005-04-27 2009-03-26 Cook Robert O Use of surface tension reducing agents in aerosol formulations
WO2007003516A2 (en) * 2005-07-01 2007-01-11 Cinvention Ag Medical devices comprising a reticulated composite material
AU2006265193A1 (en) * 2005-07-01 2007-01-11 Cinvention Ag Process for the production of porous reticulated composite materials
JP2009511727A (ja) * 2005-10-18 2009-03-19 シンベンション アーゲー 熱硬化粒子及びその製造方法
CN101646402A (zh) * 2007-01-19 2010-02-10 金文申有限公司 用粉末模塑法制成的多孔、不可降解植入物
JP6871919B2 (ja) * 2015-06-16 2021-05-19 ナノファギックス エルエルシー 薬物送達及びイメージング化学コンジュゲート、製剤及びその使用方法
JP6867639B2 (ja) * 2016-10-11 2021-05-12 学校法人 聖マリアンナ医科大学 非イオン性ヨード造影剤の結合体

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL239757A (de) * 1958-06-03
US3144479A (en) * 1958-08-07 1964-08-11 Chemie Linz Ag New iodine-containing benzoic acid esters
DE1082368B (de) * 1958-08-11 1960-05-25 Lentia Gmbh Roentgenkontrastmittel
US3317569A (en) * 1963-03-01 1967-05-02 Sterling Drug Inc Esters of monoiodinated benzoyloxyalkanoic acids
US3484481A (en) * 1965-04-09 1969-12-16 Chemie Linz Ag 3-amino-2,4,6-triiodobenzoic acid derivatives
US4924009A (en) * 1987-06-03 1990-05-08 Bowling Green State University Xanthene dye complexes
GB8900376D0 (en) * 1989-01-09 1989-03-08 Nycomed As Iodinated esters
US5145684A (en) * 1991-01-25 1992-09-08 Sterling Drug Inc. Surface modified drug nanoparticles
AU642066B2 (en) * 1991-01-25 1993-10-07 Nanosystems L.L.C. X-ray contrast compositions useful in medical imaging
US5330739A (en) * 1992-12-04 1994-07-19 Sterling Winthrop Inc. Iodinated benzoyl acetals and ketals for x-ray imaging
US5322679A (en) * 1992-12-16 1994-06-21 Sterling Winthrop Inc. Iodinated aroyloxy esters
US5346688A (en) * 1992-12-16 1994-09-13 Sterling Winthrop Inc. Iodinated wetting agents

Also Published As

Publication number Publication date
SK142593A3 (en) 1994-07-06
US5466433A (en) 1995-11-14
IL107796A0 (en) 1994-02-27
FI935308A0 (fi) 1993-11-29
AU666220B2 (en) 1996-02-01
NO934333L (no) 1994-06-17
NZ248673A (en) 1995-09-26
FI935308L (fi) 1994-06-17
CZ274893A3 (en) 1994-07-13
JPH06199754A (ja) 1994-07-19
EP0603922B1 (de) 1997-07-23
NO934333D0 (no) 1993-11-30
DE69312446D1 (de) 1997-09-04
AU4737593A (en) 1994-06-30
HUT65772A (en) 1994-07-28
CA2106413A1 (en) 1994-06-17
US5322679A (en) 1994-06-21
HU9303593D0 (en) 1994-04-28
FI935308A7 (fi) 1994-06-17
ATE155772T1 (de) 1997-08-15
KR940014293A (ko) 1994-07-18
EP0603922A1 (de) 1994-06-29

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