PH30917A - Novel cyclosporin galenic forms. - Google Patents

Novel cyclosporin galenic forms.

Info

Publication number: PH30917A
Authority: PH; Philippines
Prior art keywords: galenic forms; novel cyclosporin; cyclosporin galenic; novel; forms
Prior art date: 1989-02-09

Application number

PH40014A

Inventor

Hauer Birgit

Posanski Ulrich

Original Assignee

Sandoz Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-02-09

Filing date

1990-02-07

Publication date

1997-12-23

1989-02-09 Priority claimed from GB898902901A external-priority patent/GB8902901D0/en

1989-02-09 Priority claimed from GB898902898A external-priority patent/GB8902898D0/en

1989-02-13 Priority claimed from GB898903147A external-priority patent/GB8903147D0/en

1989-02-17 Priority claimed from GB898903663A external-priority patent/GB8903663D0/en

1990-02-07 Application filed by Sandoz Ltd filed Critical Sandoz Ltd

1997-12-23 Publication of PH30917A publication Critical patent/PH30917A/en

Links

PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 title 1
229930105110 Cyclosporin A Natural products 0.000 title 1
108010036949 Cyclosporine Proteins 0.000 title 1
229960001265 ciclosporin Drugs 0.000 title 1
229930182912 cyclosporin Natural products 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/485—Inorganic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Immunology (AREA)
Epidemiology (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Gastroenterology & Hepatology (AREA)
Physical Education & Sports Medicine (AREA)
Orthopedic Medicine & Surgery (AREA)
Rheumatology (AREA)
Diabetes (AREA)
Biophysics (AREA)
Inorganic Chemistry (AREA)
Biochemistry (AREA)
Oil, Petroleum & Natural Gas (AREA)
Dermatology (AREA)
Neurology (AREA)
Pain & Pain Management (AREA)
Hematology (AREA)
Tropical Medicine & Parasitology (AREA)
Transplantation (AREA)
Medicinal Preparation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

PH40014A 1989-02-09 1990-02-07 Novel cyclosporin galenic forms. PH30917A (en)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
GB898902901A GB8902901D0 (en)	1989-02-09	1989-02-09	Improvements in or relating to organic compounds
GB898902898A GB8902898D0 (en)	1989-02-09	1989-02-09	Improvements in or relating to organic compounds
GB898903147A GB8903147D0 (en)	1989-02-13	1989-02-13	Improvements in or relating to organic compounds
GB898903663A GB8903663D0 (en)	1989-02-17	1989-02-17	Improvements in or relating to organic compounds

Publications (1)

Publication Number	Publication Date
PH30917A true PH30917A (en)	1997-12-23

Family

ID=27450262

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PH40014A PH30917A (en)	1989-02-09	1990-02-07	Novel cyclosporin galenic forms.

Country Status (25)

Country	Link
JP (3)	JP3484190B2 (en)
KR (1)	KR0170769B1 (en)
AT (1)	AT404552B (en)
AU (1)	AU630413B2 (en)
BE (1)	BE1003009A5 (en)
CA (1)	CA2009533C (en)
CH (1)	CH679277A5 (en)
CY (1)	CY1903A (en)
DE (1)	DE4003844B4 (en)
DK (1)	DK176209B1 (en)
ES (1)	ES2021942A6 (en)
FI (1)	FI97524C (en)
FR (1)	FR2642650B1 (en)
GB (1)	GB2230440B (en)
HK (1)	HK37296A (en)
HU (1)	HU213394B (en)
IT (1)	IT1240758B (en)
LU (1)	LU87675A1 (en)
MY (1)	MY107377A (en)
NL (1)	NL195028C (en)
NO (1)	NO301576B1 (en)
NZ (1)	NZ232401A (en)
PH (1)	PH30917A (en)
PT (1)	PT93079B (en)
SE (1)	SE511398C2 (en)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
KR0148748B1 (en) *	1988-09-16	1998-08-17	장 크라메르, 한스 루돌프 하우스	Pharmaceutical composition containing cyclosporin
HU208491B (en) *	1990-11-27	1993-11-29	Gyogyszerkutato Intezet	Process for producing oral pharmaceutical composition containing cyclosporin
MX9201782A (en) †	1991-04-19	1992-10-01	Sandoz Ag	PARTICLES OF BIOLOGICALLY ACTIVE SUBSTANCES, SUBSTANTIALLY INSOLUBLE IN WATER, PROCESS FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITION THAT CONTAINS THEM.
GB9113872D0 (en) *	1991-06-27	1991-08-14	Sandoz Ag	Improvements in or relating to organic compounds
US6262022B1 (en)	1992-06-25	2001-07-17	Novartis Ag	Pharmaceutical compositions containing cyclosporin as the active agent
SG45449A1 (en)	1992-05-13	1998-01-16	Sandoz Ltd	Ophthalmic compositions
US5759566A (en) *	1992-07-28	1998-06-02	Poli Industria Chimica Spa	Microemulsion pharmaceutical compositions for the delivery of pharmaceutically active agents
DK0589843T3 (en)	1992-09-25	2002-04-02	Novartis Ag	Cyclosporin-containing pharmaceutical preparations
DE4412201A1 (en) *	1993-04-20	1994-11-10	Rentschler Arzneimittel	New pharmaceutical preparations for oral administration containing cyclosporin
ATE218878T1 (en) *	1993-04-20	2002-06-15	Novartis Erfind Verwalt Gmbh	NEW PHARMACEUTICAL PREPARATIONS FOR ORAL ADMINISTRATION CONTAINING CYCLOSPORINE
DE4340781C3 (en) *	1993-11-30	2000-01-27	Novartis Ag	Liquid preparations containing cyclosporin and process for their preparation
KR0146671B1 (en) *	1994-02-25	1998-08-17	김충환	Cyclosporin-containing powder composition
ES2177652T3 (en)	1994-11-03	2002-12-16	Novartis Ag	NEW FORMS OF PREPARATION OF CYCLOSPORINE FOR ORAL APPLICATION WITH SIMPLE COMPOSITION AND HIGH BIODISPONIBILITY, AND PROCEDURE FOR OBTAINING IT.
US5679566A (en) *	1995-01-20	1997-10-21	University Of Massachusetts Medical Center	Yeast NMD2 gene
US5766629A (en) *	1995-08-25	1998-06-16	Sangstat Medical Corporation	Oral cyclosporin formulations
US5962019A (en) *	1995-08-25	1999-10-05	Sangstat Medical Corporation	Oral cyclosporin formulations
US5827822A (en) *	1996-03-25	1998-10-27	Sangstat Medical Corporation	Cyclosporin a formulations as nanoparticles
US5834017A (en) *	1995-08-25	1998-11-10	Sangstat Medical Corporation	Oral cyclopsporin formulations
DE19544507B4 (en)	1995-11-29	2007-11-15	Novartis Ag	Cyclosporin containing preparations
US5798333A (en) *	1996-09-17	1998-08-25	Sherman; Bernard C.	Water-soluble concentrates containing cyclosporins
AU762247B2 (en) *	1997-01-30	2003-06-19	Novartis Ag	Oil-free pharmaceutical compositions containing cyclosporin A
KR20050084502A (en) *	1997-01-30	2005-08-26	노파르티스 아게	Oil-free pharmaceutical compositions containing cyclosporin a
KR100966245B1 (en) *	1997-03-12	2010-06-28	아보트 러보러터리즈	Hydrophilic two-way system for cyclosporin administration
NZ328751A (en) *	1997-09-16	1999-01-28	Bernard Charles Sherman	Solid medicament containing an anionic surfactant and cyclosporin
US6447806B1 (en)	1999-02-25	2002-09-10	Novartis Ag	Pharmaceutical compositions comprised of stabilized peptide particles
EP2116228A1 (en)	2001-10-19	2009-11-11	Isotechnika Inc.	Novel cyclosporin analog microemulsion preconcentrates
US6979672B2 (en)	2002-12-20	2005-12-27	Polichem, S.A.	Cyclosporin-based pharmaceutical compositions
JP4521554B2 (en) *	2004-03-31	2010-08-11	マイラン製薬株式会社	Cyclosporine preparation
US8333989B2 (en) *	2005-10-26	2012-12-18	Banner Pharmacaps, Inc.	Hydrophilic vehicle-based dual controlled release matrix system
AU2007230716B2 (en)	2006-03-28	2012-05-03	Javelin Pharmaceuticals, Inc.	Formulations of low dose diclofenac and beta-cyclodextrin
US7495024B2 (en)	2006-08-07	2009-02-24	Via Pharmaceuticals, Inc.	Phenylalkyl N-hydroxyureas for combating atherosclerotic plaque
DE102008059201A1 (en) *	2008-11-27	2010-06-02	GÖPFERICH, Achim, Prof. Dr.	In situ precipitating drug solutions
KR102146704B1 (en)	2018-04-13	2020-08-21	가천대학교 산학협력단	Cyclosporin a containing microstructures for transdermal and intradermal drug delivery
KR20240070705A (en) *	2021-10-13	2024-05-21	추가이 세이야쿠 가부시키가이샤	Compositions Comprising Peptide Compounds and Surfactants
KR20250002095A (en) *	2022-05-02	2025-01-07	추가이 세이야쿠 가부시키가이샤	Composition comprising a peptide compound for use in combination with a surfactant

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE445174B (en) *	1978-03-07	1986-06-09	Sandoz Ag	PHARMACEUTICAL COMPOSITION CONTAINING A CYCLOSPORIN AND A HEALING SUBSTANCE
JPS61280435A (en) *	1985-04-04	1986-12-11	Kanji Takada	Lymph orienting preparation of cyclosporin
NL8600050A (en) *	1986-01-13	1987-08-03	Sanico Nv	PHARMACEUTICAL PREPARATION WITH DELAYED DELIVERY OF THE ACTIVE SUBSTANCE AND METHOD FOR PREPARING IT.
GB8602372D0 (en) *	1986-01-31	1986-03-05	Sandoz Ltd	Organic compounds
CA1290249C (en) *	1986-04-09	1991-10-08	Cetus Corporation	COMBINATION THERAPY USING INTERLEUKIN-2 AND/OR INTERFERON-.beta. AND TUMOR NECROSIS FACTOR
EP0267615A3 (en) *	1986-11-13	1989-05-03	Sloan-Kettering Institute For Cancer Research	Compositions and method for treatment of cancer using monoclonal antibody against gd3 ganglioside together with il-2
ES2059558T3 (en) *	1987-06-17	1994-11-16	Sandoz Ag	CYCLOSPORINS AND THEIR USE AS PHARMACEUTICAL PRODUCTS.
JP2536876B2 (en) *	1987-07-31	1996-09-25	寛治高田	Dissolvable powder formulation of cyclosporine
US5756450A (en) *	1987-09-15	1998-05-26	Novartis Corporation	Water soluble monoesters as solubilisers for pharmacologically active compounds and pharmaceutical excipients and novel cyclosporin galenic forms
HU205010B (en) *	1987-09-15	1992-03-30	Sandoz Ag	Process for producing pharmaceutical compositions comprising compounds soluble up to 1 per cent and having medical activity
DE3830494B4 (en) *	1987-09-15	2006-05-18	Novartis Ag	Water-soluble monoesters as solubilizers for pharmacologically active substances and pharmaceutical excipients
JP2792862B2 (en) *	1988-07-30	1998-09-03	寛治高田	Oral enteric formulation
KR0148748B1 (en) *	1988-09-16	1998-08-17	장 크라메르, 한스 루돌프 하우스	Pharmaceutical composition containing cyclosporin
JPH1038029A (en) *	1996-07-26	1998-02-13	Ebara Corp	Dick shape structure with vibration damping function
JPH10280435A (en) *	1997-04-03	1998-10-20	Sekisui Chem Co Ltd	How to build a basement

1990
- 1990-02-05 BE BE9000133A patent/BE1003009A5/en not_active IP Right Cessation
- 1990-02-05 GB GB9002504A patent/GB2230440B/en not_active Expired - Lifetime
- 1990-02-05 CH CH359/90A patent/CH679277A5/de not_active IP Right Cessation
- 1990-02-05 FR FR9001389A patent/FR2642650B1/en not_active Expired - Lifetime
- 1990-02-07 NZ NZ232401A patent/NZ232401A/en unknown
- 1990-02-07 LU LU87675A patent/LU87675A1/en unknown
- 1990-02-07 FI FI900604A patent/FI97524C/en active IP Right Grant
- 1990-02-07 CA CA002009533A patent/CA2009533C/en not_active Expired - Lifetime
- 1990-02-07 PT PT93079A patent/PT93079B/en not_active IP Right Cessation
- 1990-02-07 HU HU90701A patent/HU213394B/en unknown
- 1990-02-07 NO NO900577A patent/NO301576B1/en not_active IP Right Cessation
- 1990-02-07 DK DK199000327A patent/DK176209B1/en not_active IP Right Cessation
- 1990-02-07 PH PH40014A patent/PH30917A/en unknown
- 1990-02-07 SE SE9000441A patent/SE511398C2/en not_active Application Discontinuation
- 1990-02-07 MY MYPI90000191A patent/MY107377A/en unknown
- 1990-02-08 AU AU49252/90A patent/AU630413B2/en not_active Expired
- 1990-02-08 JP JP03134890A patent/JP3484190B2/en not_active Expired - Lifetime
- 1990-02-08 AT AT0027290A patent/AT404552B/en not_active IP Right Cessation
- 1990-02-08 IT IT47609A patent/IT1240758B/en active IP Right Grant
- 1990-02-08 KR KR1019900001492A patent/KR0170769B1/en not_active Expired - Lifetime
- 1990-02-08 DE DE4003844A patent/DE4003844B4/en not_active Expired - Lifetime
- 1990-02-08 NL NL9000299A patent/NL195028C/en not_active IP Right Cessation
- 1990-02-09 ES ES9000397A patent/ES2021942A6/en not_active Expired - Lifetime
1996
- 1996-03-07 HK HK37296A patent/HK37296A/en not_active IP Right Cessation
- 1996-11-22 CY CY190396A patent/CY1903A/en unknown
2001
- 2001-04-25 JP JP2001127538A patent/JP4073641B2/en not_active Expired - Lifetime
2005
- 2005-09-13 JP JP2005265724A patent/JP2006001947A/en active Pending

Also Published As

Publication number	Publication date
CA2009533C (en)	2002-11-12
MY107377A (en)	1995-11-30
IT9047609A0 (en)	1990-02-08
JP2006001947A (en)	2006-01-05
SE9000441D0 (en)	1990-02-07
DE4003844A1 (en)	1990-08-16
HU213394B (en)	1997-06-30
NO900577L (en)	1990-08-10
NO900577D0 (en)	1990-02-07
PT93079A (en)	1990-08-31
IT1240758B (en)	1993-12-17
JP4073641B2 (en)	2008-04-09
SE511398C2 (en)	1999-09-20
SE9000441L (en)	1991-08-08
FR2642650B1 (en)	1994-12-09
JPH02235817A (en)	1990-09-18
AU4925290A (en)	1990-08-16
AU630413B2 (en)	1992-10-29
JP3484190B2 (en)	2004-01-06
FI97524B (en)	1996-09-30
GB9002504D0 (en)	1990-04-04
FI97524C (en)	1997-01-10
FI900604A0 (en)	1990-02-07
ES2021942A6 (en)	1991-11-16
LU87675A1 (en)	1991-10-08
CY1903A (en)	1996-11-22
GB2230440B (en)	1993-05-19
JP2001302538A (en)	2001-10-31
CA2009533A1 (en)	1990-08-09
FR2642650A1 (en)	1990-08-10
BE1003009A5 (en)	1991-10-22
DK32790A (en)	1990-08-10
KR900012625A (en)	1990-09-01
NO301576B1 (en)	1997-11-17
DE4003844B4 (en)	2007-09-20
NL195028C (en)	2003-12-02
AT404552B (en)	1998-12-28
ATA27290A (en)	1998-05-15
KR0170769B1 (en)	1999-02-01
IT9047609A1 (en)	1991-08-08
GB2230440A (en)	1990-10-24
NL9000299A (en)	1990-09-03
DK176209B1 (en)	2007-02-05
NL195028B (en)	2003-08-01
HU900701D0 (en)	1990-04-28
HK37296A (en)	1996-03-15
DK32790D0 (en)	1990-02-07
CH679277A5 (en)	1992-01-31
PT93079B (en)	1996-04-30
NZ232401A (en)	1992-10-28

Publication	Publication Date	Title
GB2228198B (en)	1992-12-16	Novel cyclosporin galenic forms
GB2230440B (en)	1993-05-19	Novel cyclosporin galenic forms
DE69014117D1 (en)	1994-12-15	Radiotherapiesystem.
EP0593428A4 (en)	1992-09-01	Myconematicide.
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DE69012800D1 (en)	1994-10-27	Hüftprothese.
GR3018421T3 (en)	1996-03-31	Glutarimides.
DE69001591D1 (en)	1993-06-17	Tuerschliesser.
DE69013160D1 (en)	1994-11-10	Reibscheibentoroidgetriebe.
DE68907587D1 (en)	1993-08-19	Trappingssystem.
DE69013161D1 (en)	1994-11-10	Reibscheibentoroidalgetriebe.
GB2235734B (en)	1993-08-25	Turbo-rotor construction.
OA09196A (en)	1992-06-30	"Tétrahydroimidazo (1,4) benzodiazépin-2-thiones antivirales".
DE59001953D1 (en)	1993-08-19	Interferometeranordnung.
DE59006531D1 (en)	1994-08-25	Interferometeranordnung.
DE69022965D1 (en)	1995-11-16	Aminopiperazinderivate.
DE59008181D1 (en)	1995-02-16	Trifluormethylcyclohexan-derivate.
DE69002778D1 (en)	1993-09-23	Pyrolytisches bornitrid.
DE69008186D1 (en)	1994-05-19	Allylhydroperoxidkettenübertragungsmittel.
ZA904897B (en)	1991-03-27	Vip-analogs ii.
DE59001720D1 (en)	1993-07-15	Spruehvorrichtung.
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ZA903177B (en)	1990-12-28	N-sulfenyl-and n-sulfinyl-n,n'-diacylhydrazides