PH31621A - Pharmaceutical compositions. - Google Patents

Pharmaceutical compositions.

Info

Publication number: PH31621A
Authority: PH; Philippines
Prior art keywords: pharmaceutical compositions; psoriasis; malignant; esters; salts
Prior art date: 1992-01-22

Application number

PH45577A

Other languages

English (en)

Inventor

Bollag Werner

Grippo Joseph Francis

Levin Arthur

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-01-22

Filing date

1993-01-19

Publication date

1999-01-12

1993-01-19 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

1999-01-12 Publication of PH31621A publication Critical patent/PH31621A/en

Links

239000008194 pharmaceutical composition Substances 0.000 title 1
SHGAZHPCJJPHSC-ZVCIMWCZSA-N 9-cis-retinoic acid Chemical compound OC(=O)/C=C(\C)/C=C/C=C(/C)\C=C\C1=C(C)CCCC1(C)C SHGAZHPCJJPHSC-ZVCIMWCZSA-N 0.000 abstract 1
201000004681 Psoriasis Diseases 0.000 abstract 1
229960001445 alitretinoin Drugs 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
208000035475 disorder Diseases 0.000 abstract 1
230000009841 epithelial lesion Effects 0.000 abstract 1
150000002148 esters Chemical class 0.000 abstract 1
230000003211 malignant effect Effects 0.000 abstract 1
230000008832 photodamage Effects 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
210000002374 sebum Anatomy 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/07—Retinol compounds, e.g. vitamin A
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Dermatology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Medicinal Preparation (AREA)
Fats And Perfumes (AREA)
Saccharide Compounds (AREA)

PH45577A 1992-01-22 1993-01-19 Pharmaceutical compositions. PH31621A (en)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date
US82374192A	1992-01-22	1992-01-22
US82392892A	1992-01-22	1992-01-22
US82378692A	1992-01-22	1992-01-22
US82464792A	1992-01-23	1992-01-23

Publications (1)

Publication Number	Publication Date
PH31621A true PH31621A (en)	1999-01-12

Family

ID=27505866

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PH45577A PH31621A (en)	1992-01-22	1993-01-19	Pharmaceutical compositions.

Country Status (20)

Country	Link
EP (1)	EP0552624B1 (es)
JP (1)	JP3631259B2 (es)
CN (2)	CN1068200C (es)
AT (1)	ATE194077T1 (es)
AU (1)	AU667864B2 (es)
CA (1)	CA2087251C (es)
CY (1)	CY2251B1 (es)
CZ (1)	CZ282548B6 (es)
DE (1)	DE69328910T2 (es)
DK (1)	DK0552624T3 (es)
ES (1)	ES2148184T3 (es)
GR (1)	GR3034323T3 (es)
HU (2)	HU212734B (es)
IL (1)	IL104450A (es)
NO (1)	NO302274B1 (es)
NZ (1)	NZ245686A (es)
PH (1)	PH31621A (es)
PT (1)	PT552624E (es)
RU (1)	RU2119333C1 (es)
TW (1)	TW226329B (es)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE617614T1 (de)	1991-12-18	1995-06-08	Baylor College Of Medicine, Houston, Tex.	Mitteln zur modulierung von verfahren durch retinoid rezeptoren und dafür nützliche verbindungen.
US5968989A (en)	1991-12-18	1999-10-19	The Salk Institute For Biological Studies	Means for the modulation of processes mediated by retinoid receptors and compounds useful therefor
US7056954B2 (en)	1991-12-18	2006-06-06	The Salk Institute For Biological Studies	Means for the modulation of processes mediated by retinoid receptors and compounds useful therefor
US5780676A (en) *	1992-04-22	1998-07-14	Ligand Pharmaceuticals Incorporated	Compounds having selective activity for Retinoid X Receptors, and means for modulation of processes mediated by Retinoid X Receptors
US5962731A (en) *	1992-04-22	1999-10-05	Ligand Pharmaceuticals Incorporated	Compounds having selective activity for retinoid X receptors, and means for modulation of processes mediated by retinoid X receptors
US7655699B1 (en)	1992-04-22	2010-02-02	Eisai Inc.	Compounds having selective activity for retinoid X receptors, and means for modulation of processes mediated by retinoid X receptors
US5549888A (en) *	1994-01-31	1996-08-27	Procter & Gamble	Aqueous topical anti-acne compositions of low pH
US5534261A (en) *	1995-01-17	1996-07-09	University Of Southern California	Retinoid-based compositions and method for preventing adhesion formation using the same
US7115728B1 (en)	1995-01-30	2006-10-03	Ligand Pharmaceutical Incorporated	Human peroxisome proliferator activated receptor γ
US5821254A (en) *	1995-02-17	1998-10-13	The United States Of America As Represented By The Department Of Health And Human Services	Uses of 9-cis-retinoic acids and derivatives thereof alone or in combination with antineoplastic agents in the prevention or treatment of cancer
US5807900A (en) *	1995-03-31	1998-09-15	Hoffmann-La Roche, Inc.	Method for identifying compounds having increased activity for the repair of skin photodamage
AU5721096A (en) *	1995-04-21	1996-11-07	Ligand Pharmaceuticals Incorporated	Inhibition of apoptosis in cells expressing fas-ligand follo wing activation
DE19523079A1 (de) *	1995-06-26	1997-01-02	Basf Ag	Ester und Amide der 9(Z)-Retinsäure
EP0788353A1 (en)	1995-09-18	1997-08-13	Ligand Pharmaceuticals, Inc.	Ppar gamma antagonists for treating obesity
PT859608E (pt) *	1995-09-18	2004-06-30	Ligand Pharm Inc	Tratamento de niddm com agonistas de rxr
TW442459B (en) *	1996-04-15	2001-06-23	Hoffmann La Roche	Retinoid compounds, pharmaceutical composition comprising same and process for the preparation thereof
FR2765480B1 (fr)	1997-07-07	1999-09-10	Oreal	Utilisation pour le revetement des matieres keratiniques d'un materiau polymerique hybride ; compositions cosmetiques ou dermatologiques
WO1999005161A1 (en)	1997-07-25	1999-02-04	Ligand Pharmaceuticals Incorporated	HUMAN PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA (PPARη) GENE REGULATORY SEQUENCES AND USES THEREFOR
AU1707599A (en) *	1998-03-20	1999-10-18	Warner-Lambert Company	Retinoid-glitazone combinations
HUP0200996A3 (en)	1999-04-07	2003-01-28	Sankyo Company Ltd Chuo Ku	Amine derivatives, pharmaceutical compositions containing them and their use
CA2392453C (en) *	1999-11-23	2012-03-20	Gerhart Graupner	Modulation of signal transduction
RU2214830C2 (ru) *	2001-12-03	2003-10-27	Рязанский государственный медицинский университет им. акад. И.П.Павлова	Способ лечения и профилактики местных лучевых реакций на коже
JP5249484B2 (ja) *	2001-12-11	2013-07-31	第一三共株式会社	医薬組成物
RU2197235C1 (ru) *	2002-04-05	2003-01-27	Фармацевтическое научно-производственное предприятие "Ретиноиды" (акционерное общество закрытого типа)	Раствор для лечения заболеваний кожи, способ его получения и способ лечения заболеваний кожи
US20050245440A1 (en) *	2002-04-05	2005-11-03	University Of Utah Research Foundation	Regulation of a novel colon specific retinol dehydrogenase by apc and cdx2
US20040122110A1 (en) *	2002-09-06	2004-06-24	Maccabee Mendy S.	Effect of vitamin A gel on paranasal sinus mucosal regeneration
EP1527774A1 (en)	2003-11-03	2005-05-04	Basilea Pharmaceutica AG	New formulation for retinoid-containing soft gelatin capsules
JP4825957B2 (ja) *	2005-03-29	2011-11-30	国立大学法人鹿児島大学	抗腫瘍剤
RU2546005C2 (ru)	2009-09-15	2015-04-10	Кью Эл Ти ИНК.	Фармацевтические составы, содержащие 9-цис-ретиниловые сложные эфиры в липидном наполнителе
JP2013527155A (ja) *	2010-04-16	2013-06-27	ダボスライフサイエンスピーティーイー．リミテッド	皮膚科用途のための少なくとも１つのビタミンｅ成分およびチロシナーゼ阻害剤の相乗的相互作用
SG10201507819VA (en)	2010-04-19	2015-10-29	Quadra Logic Tech Inc	Therapeutic Regimen And Methods For Treating Or Ameliorating Visual Disorders Associated With An Endogenous Retinoid Deficiency
AU2013232697B2 (en)	2012-03-01	2017-10-19	Eluminex Biosciences (Suzhou) Limited	Therapeutic regimens and methods for improving visual function in visual disorders associated with an endogenous retinoid deficiency
JP6182728B2 (ja) *	2012-11-02	2017-08-23	国立大学法人名古屋大学	幹細胞を標的とした薬効及び毒性の評価法
US20230320967A1 (en)	2020-09-11	2023-10-12	Chemyunion Ltda.	Composition, use of the composition, cosmetic method for modulating the production of sebum
EP4489744A4 (en) *	2022-03-08	2025-11-05	Mastery Biotech Co Ltd	PHARMACEUTICAL COMPOSITION COMPRISING RETINOIC ACID AND A CARBOHYDRATE AND ITS USE
WO2025077810A1 (zh) *	2023-10-12	2025-04-17	南京纽邦生物科技有限公司	预防或延缓皮肤衰老及维持或改善皮肤状况的方法和组合物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ZA713539B (en) *	1970-06-23	1972-02-23	Hoffmann La Roche	Pharmaceutical compositions
WO1988007857A1 (en) *	1987-04-06	1988-10-20	Daltex Medical Sciences, Inc.	Treatment of aged skin with oral 13-cis-retinoic acid
US4994491A (en) *	1988-12-14	1991-02-19	Molecular Design International	Dermal uses of trans-retinoids for the treatment of cancer
LU86969A1 (fr) *	1987-08-12	1989-03-08	Oreal	Association de derives de pyrimidine et de retinoides en composants separes pour induire et stimuler la croissance des cheveux et diminuer leur chute
DE617614T1 (de) *	1991-12-18	1995-06-08	Baylor College Of Medicine, Houston, Tex.	Mitteln zur modulierung von verfahren durch retinoid rezeptoren und dafür nützliche verbindungen.

1992
- 1992-12-17 CZ CS923728A patent/CZ282548B6/cs not_active IP Right Cessation
- 1992-12-24 TW TW081110357A patent/TW226329B/zh active
1993
- 1993-01-11 EP EP93100257A patent/EP0552624B1/en not_active Expired - Lifetime
- 1993-01-11 PT PT93100257T patent/PT552624E/pt unknown
- 1993-01-11 ES ES93100257T patent/ES2148184T3/es not_active Expired - Lifetime
- 1993-01-11 AT AT93100257T patent/ATE194077T1/de not_active IP Right Cessation
- 1993-01-11 DE DE69328910T patent/DE69328910T2/de not_active Expired - Lifetime
- 1993-01-11 DK DK93100257T patent/DK0552624T3/da active
- 1993-01-13 CA CA002087251A patent/CA2087251C/en not_active Expired - Fee Related
- 1993-01-15 NZ NZ245686A patent/NZ245686A/en not_active IP Right Cessation
- 1993-01-18 AU AU31861/93A patent/AU667864B2/en not_active Expired
- 1993-01-18 HU HU9300116A patent/HU212734B/hu not_active IP Right Cessation
- 1993-01-19 PH PH45577A patent/PH31621A/en unknown
- 1993-01-20 JP JP02342993A patent/JP3631259B2/ja not_active Expired - Fee Related
- 1993-01-20 IL IL104450A patent/IL104450A/xx not_active IP Right Cessation
- 1993-01-20 RU RU93005355A patent/RU2119333C1/ru not_active IP Right Cessation
- 1993-01-21 NO NO930206A patent/NO302274B1/no not_active IP Right Cessation
- 1993-01-21 CN CN93100632A patent/CN1068200C/zh not_active Expired - Fee Related
1995
- 1995-06-19 HU HU95P/P00256P patent/HU211167A9/hu unknown
1999
- 1999-12-15 CN CNB99126469XA patent/CN1155376C/zh not_active Expired - Fee Related
2000
- 2000-09-04 GR GR20000402010T patent/GR3034323T3/el not_active IP Right Cessation
2001
- 2001-12-11 CY CY0100043A patent/CY2251B1/xx unknown

Also Published As

Publication number	Publication date
NZ245686A (en)	1995-05-26
JP3631259B2 (ja)	2005-03-23
HUT63053A (en)	1993-07-28
CN1155376C (zh)	2004-06-30
HU211167A9 (en)	1995-11-28
RU2119333C1 (ru)	1998-09-27
NO302274B1 (no)	1998-02-16
PT552624E (pt)	2000-10-31
JPH06107542A (ja)	1994-04-19
CZ372892A3 (en)	1993-12-15
ATE194077T1 (de)	2000-07-15
AU667864B2 (en)	1996-04-18
EP0552624A1 (en)	1993-07-28
NO930206L (no)	1993-07-23
CN1256916A (zh)	2000-06-21
TW226329B (es)	1994-07-11
ES2148184T3 (es)	2000-10-16
CA2087251A1 (en)	1993-07-23
DE69328910T2 (de)	2001-01-11
CZ282548B6 (cs)	1997-08-13
CN1074826A (zh)	1993-08-04
DE69328910D1 (de)	2000-08-03
NO930206D0 (no)	1993-01-21
HU212734B (en)	1996-10-28
AU3186193A (en)	1993-07-29
CY2251B1 (en)	2003-07-04
HU9300116D0 (en)	1993-04-28
CA2087251C (en)	2003-06-24
GR3034323T3 (en)	2000-12-29
IL104450A (en)	1997-03-18
DK0552624T3 (da)	2000-09-25
EP0552624B1 (en)	2000-06-28
IL104450A0 (en)	1993-05-13
CN1068200C (zh)	2001-07-11

Publication	Publication Date	Title
CY2251B1 (en)	2003-07-04	Pharmaceutical compositions containing 9-cis retinoic acid salts and esters thereof
RU93005355A (ru)	1995-09-27	Фармакологические композиции
AU2080988A (en)	1989-01-30	Esters of 13-trans-retinoic acid
EP0303915A3 (en)	1990-08-08	Retinoids for the treatment of skin damaged by light
AU4156493A (en)	1994-01-13	Compositions containing retinoic acids and tocopherol
ZA903339B (en)	1992-01-29	Method of topically treating acne vulgaris
DE3568272D1 (en)	1989-03-23	4-vinylbenzoic-acid derivatives, their preparation and their use as therapeutical compositions and as ligands
ATE181231T1 (de)	1999-07-15	Verfahren zur hautpflege und mittel
IT1223290B (it)	1990-09-19	Acidi poliinsaturi ad azione vasocinetica e relative formulazioni farmaceutiche e cosmetiche
DE69315927D1 (de)	1998-02-05	Kosmetische Zusammensetzung, die einen Lipidstoff und eine Hydroxy - oder Ketofettsäure enthält
AU6333794A (en)	1994-12-01	Retinoid composition
DE3485337D1 (de)	1992-01-23	Topische zubereitungen mit gehalt an teer und fettsaeuren.
KR930016100A (ko)	1993-08-26	약제학적 조성물
GR3026086T3 (en)	1998-05-29	L-carnitine salt and cosmetic and pharmaceutical compositions containing same for treating dermatoses
IL90056A0 (en)	1989-12-15	Topical pharmaceutical compositions containing 4-quinoline carboxylic acid derivatives
ATE113209T1 (de)	1994-11-15	Verwendung von 5-amino-salicylsäure für die behandlung von hautkrankheiten.
IE873478L (en)	1988-06-22	Use of 13-cis retinoic acid
ATE179889T1 (de)	1999-05-15	Arzneimittel, die ester omega-3 polyungesättigter säuren enthalten und deren verwendung in der topischen behandlung morbider erkrankungen
ES2064958T3 (es)	1995-02-01	Gel acuoso a base de acido retinoico y de hidroxipropil-beta-ciclodextrina.
EP0357646A4 (en)	1991-05-08	Treatment of aged skin with oral 13-cis-retinoic acid
IT9019422A1 (it)	1991-08-21	Composizioni farmaceutiche ad attivita' depigmentante e contro il danneggiamento cutaneo fotoindotto.
CA2033183A1 (en)	1990-11-23	Water-soluble vitamin a preparations for application to the skin
CA2062422A1 (en)	1992-09-09	Method for treating patients with precancerous lesions by administering substituted sulfonyl indenyl acetic and propionic acids and esters thereof
BG102864A (en)	1999-09-30	Application of phosphonic acid esters for the treatment of functional disorders of the brain and depressions