PL103683B1 - METHOD OF MAKING S-OXAZOLIDIN - Google Patents

METHOD OF MAKING S-OXAZOLIDIN Download PDF

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Publication number
PL103683B1
PL103683B1 PL16668169A PL16668169A PL103683B1 PL 103683 B1 PL103683 B1 PL 103683B1 PL 16668169 A PL16668169 A PL 16668169A PL 16668169 A PL16668169 A PL 16668169A PL 103683 B1 PL103683 B1 PL 103683B1
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PL
Poland
Prior art keywords
formula
propanolamine
butyl
phenyl
butylaminopropane
Prior art date
Application number
PL16668169A
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Polish (pl)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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Publication of PL103683B1 publication Critical patent/PL103683B1/en

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  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Claims (4)

Zastrzezenia patentowePatent claims 1. Sposób wytwarzania S-oksazolidyny o wzorze 2, w którym A oznacza atom wodoru, podstawiona rodnikiem fenylowym grupe sulfonyIowa lub grupe 3-morfolino-1,2,5-tiadiazoli-4-lowa, Z oznacza atom wodoru, nizszy rodnik alkilowy lub fenylowy, A Y oznacza nizszy rodnik alkilowy, znamienny tym, ze S-propanoloamine o wzorze 1 poddaje sie reakcji z aldehydem o wzorze ZCHO, przy czym w powyzszych wzorach wszystkie symbole maja wyzej podane znaczenie.A method for the preparation of an S-oxazolidine of formula II, wherein A is a hydrogen atom, a sulfonyl group substituted with a phenyl radical, or a 3-morpholine-1,2,5-thiadiazol-4-yl group, Z is a hydrogen atom, a lower alkyl radical or phenyl, AY is a lower alkyl radical, characterized in that the S-propanolamine of formula I is reacted with an aldehyde of formula ZCHO, where in the above formulas all symbols have the above meaning. 2. Sposób wedlug zastrz. 1, znamienny tym, ze S-1 ,2-dwuhydroksy-3-t-butyloaminopropan pod¬ daje sie reakcji z benzaldehydem, przy czym otrzymuje sie S-2-fenylo-3-t-butylo-5-hydroksymetylooksazolidyne.2. The method according to claim The process of claim 1, wherein S-1,2-dihydroxy-3-t-butylaminopropane is reacted with benzaldehyde to give S-2-phenyl-3-t-butyl-5-hydroxymethyloxazolidine. 3. Sposób wedlug zastrz. 1, znamienny tym, ze jako S-propanoloamine stosuje sie S-1 -sulfonylok- sy-2-hydroksy-3-t-butyloaminopropan, przy czym otrzymuje sie S-2-Z-3-t-butylo-5-sulfonyloksymetylooksazolid- yne, w której Z ma znaczenie jak w zastrz. 1.103 683 33. The method according to p. The process of claim 1, wherein S-1 -sulfonyloxy-2-hydroxy-3-t-butylaminopropane is used as S-propanolamine, which gives S-2-Z-3-t-butyl-5-sulfonyloxymethyloxazolide. yne, wherein Z is as in claim 1.103 683 3 4. Sposób wedlug zastrz. 1, znamienny tym, ze jako S-propanoloarnine stosuje sie S*3-morfollno-4' «(3 t-butyloamino-2-hydroksypropyloksy) -1 ,2,5-tiadiazol, przy czym otrzymuje sie S-2-Zv3*t-butylo£-(3*morfoli' no-1,2,5-tiadiazolo- 4-oksymetylo)-oksazolidyne, w której Z ma znaczenie jak w zastrz. 1. OH I S -A0- CH2- CH- CH2- NHY Wzór 1 S-A0-CH2-CH -CH2 l I 0 N-Y /Cx Z H IVzOr 24. The method according to p. The process of claim 1, wherein the S-propanolamine is S * 3-morpholino-4 "(3 t-butylamino-2-hydroxypropoxy) -1,2,5-thiadiazole, giving S-2-Zv3 * t-butyl E- (3 * morpholino-1,2,5-thiadiazole-4-oxymethyl) -oxazolidine, wherein Z is as in claim 1. OH I S -A0- CH2- CH- CH2- NHY Formula 1 S-A0-CH2-CH -CH2 l I 0 N-Y / Cx Z H IVzOr 2
PL16668169A 1969-04-21 1969-05-21 METHOD OF MAKING S-OXAZOLIDIN PL103683B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US81847469A 1969-04-21 1969-04-21

Publications (1)

Publication Number Publication Date
PL103683B1 true PL103683B1 (en) 1979-07-31

Family

ID=25225622

Family Applications (3)

Application Number Title Priority Date Filing Date
PL17820669A PL92132B1 (en) 1969-04-21 1969-05-21
PL16668169A PL103683B1 (en) 1969-04-21 1969-05-21 METHOD OF MAKING S-OXAZOLIDIN
PL13374569A PL85165B1 (en) 1969-04-21 1969-05-21

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL17820669A PL92132B1 (en) 1969-04-21 1969-05-21

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL13374569A PL85165B1 (en) 1969-04-21 1969-05-21

Country Status (9)

Country Link
BR (1) BR6909035D0 (en)
DK (4) DK135532B (en)
ES (1) ES367524A1 (en)
FI (1) FI55506C (en)
HU (1) HU162246B (en)
IE (1) IE34352B1 (en)
PH (1) PH15523A (en)
PL (3) PL92132B1 (en)
YU (4) YU34083B (en)

Also Published As

Publication number Publication date
FI55506C (en) 1979-08-10
YU14178A (en) 1983-01-21
PL92132B1 (en) 1977-03-31
YU293877A (en) 1979-04-30
YU22278A (en) 1982-10-31
DK135532C (en) 1977-10-24
PH15523A (en) 1983-02-09
IE34352L (en) 1970-10-21
BR6909035D0 (en) 1973-02-08
YU125369A (en) 1978-06-30
DK138647C (en) 1979-03-12
DK221575A (en) 1975-08-25
DK138422C (en) 1979-02-12
DK135532B (en) 1977-05-16
DK138018C (en) 1978-11-20
DK138422B (en) 1978-09-04
YU34692B (en) 1979-12-31
IE34352B1 (en) 1975-04-16
YU34083B (en) 1978-12-31
PL85165B1 (en) 1976-04-30
HU162246B (en) 1973-01-29
DK138018B (en) 1978-06-26
FI55506B (en) 1979-04-30
ES367524A1 (en) 1971-07-16
DK138647B (en) 1978-10-09

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