PL123236U1 - Microsystem for cell culture - Google Patents

Microsystem for cell culture

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Publication number
PL123236U1
PL123236U1 PL123236U PL12323610U PL123236U1 PL 123236 U1 PL123236 U1 PL 123236U1 PL 123236 U PL123236 U PL 123236U PL 12323610 U PL12323610 U PL 12323610U PL 123236 U1 PL123236 U1 PL 123236U1
Authority
PL
Poland
Prior art keywords
culture
microchannels
polymer
microcells
microchip
Prior art date
Application number
PL123236U
Other languages
Polish (pl)
Other versions
PL68197Y1 (en
Inventor
Elżbieta Jędrych
Karolina Ziółkowska
Maciej Skolimowski
Artur Dybko
Zbigniew Brzózka
Original Assignee
Politechnika Warszawska
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Politechnika Warszawska filed Critical Politechnika Warszawska
Priority to PL123236U priority Critical patent/PL68197Y1/en
Publication of PL123236U1 publication Critical patent/PL123236U1/en
Publication of PL68197Y1 publication Critical patent/PL68197Y1/en

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Abstract

Przedmiotem wzoru użytkowego jest mikroukład do hodowli komórkowej stosowany do prowadzenia testów z materiałem biologicznym. Mikroukład składa się dwóch połączonych płytek - szklanej (1) i polimerowej (2), w szklanej płytce (1) znajduje się macierz mikrokomór hodowlanych (3) w układzie liniowym a w płytce polimerowej (2) znajdują się mikrokanały (4) tworzące generator gradientu stężeń, zawierający dwa kanały wlotowe (5a) i (5b) do wprowadzenia dwóch stężeń badanych substancji i kanały wylotowe (6) połączone z mikrokomorami hodowlanymi (3) i łączące mikrokomory hodowlane (3) ze sobą wzdłuż mikroukładu. Od strony dwóch kanałów wlotowych (5a) i (5b) znajdują się trzy mikrokanały (4), każdy następny etap generatora gradientu stężeń utworzony przez mikrokanały (4) zawiera o jeden mikrokanał więcej a w ostatnim etapie generatora stężeń utworzonym przez mikrokanały (4) znajduje się taka ilość mikrokanałów, która odpowiada ilości linii mikrokomór hodowlanych (3). Ponadto mikroukład zawiera wywiercony w płytce polimerowej (2) otwór (7) do wprowadzenia komórek oraz pożywek hodowlanych. Mikroukład charakteryzuje się tym, że zaopatrzony jest w przezroczystą grzałkę (8) z kontaktami elektrycznymi (9) umieszczoną na spodniej stronie płytki szklanej (1).The subject of the utility model is a cell culture chip used to conduct tests with biological material. The microchip consists of two connected plates - glass (1) and polymer (2), the glass plate (1) has a culture microcell array (3) in a linear arrangement and the polymer plate (2) has microchannels (4) forming a concentration gradient generator , comprising two inlet channels (5a) and (5b) for introducing two concentrations of test substances and outlet channels (6) connected to the culture microcells (3) and connecting the culture microcells (3) together along the microchip. On the side of the two inlet channels (5a) and (5b) there are three microchannels (4), each subsequent stage of the concentration gradient generator created by the microchannels (4) contains one more microchannel and in the last stage of the concentration generator created by the microchannels (4) there is the number of microchannels that corresponds to the number of microcell culture lines (3). In addition, the microcircuit contains a hole (7) drilled in the polymer plate (7) for introducing cells and culture media. The chip is characterized by the fact that it is equipped with a transparent heater (8) with electrical contacts (9) located on the underside of the glass plate (1).

PL123236U 2010-12-13 2010-12-13 Microsystem for cell culture PL68197Y1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL123236U PL68197Y1 (en) 2010-12-13 2010-12-13 Microsystem for cell culture

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL123236U PL68197Y1 (en) 2010-12-13 2010-12-13 Microsystem for cell culture

Publications (2)

Publication Number Publication Date
PL123236U1 true PL123236U1 (en) 2015-03-02
PL68197Y1 PL68197Y1 (en) 2016-01-29

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ID=52574603

Family Applications (1)

Application Number Title Priority Date Filing Date
PL123236U PL68197Y1 (en) 2010-12-13 2010-12-13 Microsystem for cell culture

Country Status (1)

Country Link
PL (1) PL68197Y1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114653640A (en) * 2022-03-14 2022-06-24 天津市胸科医院 Cell growth inhibition experimental device for drug development

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL71591Y1 (en) * 2018-04-05 2020-11-02 Politechnika Warszawska Multifunctional flow-through micro-system

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114653640A (en) * 2022-03-14 2022-06-24 天津市胸科医院 Cell growth inhibition experimental device for drug development

Also Published As

Publication number Publication date
PL68197Y1 (en) 2016-01-29

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