PL1601646T3 - Analogi 2-podstawionej witaminy D i ich zastosowania terapeutyczne - Google Patents

Analogi 2-podstawionej witaminy D i ich zastosowania terapeutyczne

Info

Publication number
PL1601646T3
PL1601646T3 PL04718886T PL04718886T PL1601646T3 PL 1601646 T3 PL1601646 T3 PL 1601646T3 PL 04718886 T PL04718886 T PL 04718886T PL 04718886 T PL04718886 T PL 04718886T PL 1601646 T3 PL1601646 T3 PL 1601646T3
Authority
PL
Poland
Prior art keywords
analogues
vitamin
therapeutic uses
substituted vitamin
alkyl
Prior art date
Application number
PL04718886T
Other languages
English (en)
Inventor
Roger Bouillon
Annemieke Verstuyf
Maurits Vandewalle
Clercq Pierre De
Original Assignee
K U Leuven Res And Development
Univ Gent
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by K U Leuven Res And Development, Univ Gent filed Critical K U Leuven Res And Development
Publication of PL1601646T3 publication Critical patent/PL1601646T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL04718886T 2003-03-10 2004-03-10 Analogi 2-podstawionej witaminy D i ich zastosowania terapeutyczne PL1601646T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0305332.9A GB0305332D0 (en) 2003-03-10 2003-03-10 Biological evaluation of novel vitamin D analogues
EP04718886A EP1601646B1 (en) 2003-03-10 2004-03-10 2-substituted vitamin d analogues and their therapeutic uses
PCT/BE2004/000037 WO2004080922A2 (en) 2003-03-10 2004-03-10 Substituted vitamin d analogues and their therapeutic uses

Publications (1)

Publication Number Publication Date
PL1601646T3 true PL1601646T3 (pl) 2011-12-30

Family

ID=9954381

Family Applications (1)

Application Number Title Priority Date Filing Date
PL04718886T PL1601646T3 (pl) 2003-03-10 2004-03-10 Analogi 2-podstawionej witaminy D i ich zastosowania terapeutyczne

Country Status (14)

Country Link
US (1) US20060189576A1 (pl)
EP (1) EP1601646B1 (pl)
JP (1) JP2006519788A (pl)
AT (1) ATE517864T1 (pl)
AU (1) AU2004220477B8 (pl)
CA (1) CA2518531A1 (pl)
CY (1) CY1111843T1 (pl)
DK (1) DK1601646T3 (pl)
ES (1) ES2368064T3 (pl)
GB (1) GB0305332D0 (pl)
PL (1) PL1601646T3 (pl)
PT (1) PT1601646E (pl)
SI (1) SI1601646T1 (pl)
WO (1) WO2004080922A2 (pl)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008520689A (ja) 2004-11-22 2008-06-19 ウィスコンシン・アルムニ・リサーチ・ファウンデーション １９，２６，２７−トリノル−（２０Ｓ）−１α−ヒドロキシビタミンＤ３の２α−メチルおよび２β−メチル類似体およびそれらの使用
JP5161582B2 (ja) 2004-11-22 2013-03-13 ウィスコンシン・アルムニ・リサーチ・ファウンデーション １７，２０（ｚ）−デヒドロビタミンｄ類似体およびそれらの使用
AU2005309804B9 (en) * 2004-11-22 2011-12-08 Wisconsin Alumni Research Foundation 2alpha-methyl-19-nor-(20S)-1alpha-hydroxy-bishomopregnacalciferol and its uses
WO2006060885A1 (en) * 2004-12-07 2006-06-15 K.U.Leuven Research & Development 7-(2-cyclohexylidene-ethylidene)-spiro[5.5]undecanes useful for making pharmaceutical compositions
CA2605727A1 (en) 2005-05-03 2006-11-09 Wisconsin Alumni Research Foundation 19,26,27-trinor-1.alpha.,25-dihydroxyvitamin d3 compounds
US7528122B2 (en) 2006-02-02 2009-05-05 Wisconsin Alumni Research Foundation Vitamin D analog—NEL, methods and uses thereof
US7803789B2 (en) 2006-02-02 2010-09-28 Wisconsin Alumni Research Foundation Vitamin D analog—RAK, methods and uses thereof
MX2008012671A (es) 2006-04-06 2008-10-15 Wisconsin Alumni Res Found Analogos 1 a,25-dihidroxi- 19, 26,27-trinor vitamina d 2-sustituidos y sus usos.
JP2009533483A (ja) 2006-04-06 2009-09-17 ウイスコンシン アラムニ リサーチ ファンデーション ２−メチレン−１α，２５−ジヒドロキシ−１８，１９，２１−トリノルビタミンＤ３およびその使用
US7648973B2 (en) 2006-04-06 2010-01-19 Wisconsin Alumni Research Foundation 2-methylene-1α,25-dihydroxy-19,21-dinorvitamin D3 analogs and uses thereof
MX2009003241A (es) 2006-09-28 2009-05-05 Wisconsin Alumni Res Found Analogos de 2-metilen-(20r,25s)-19,27-dinor-(22e)-vitamina d.
DE602010000019D1 (de) * 2009-05-20 2011-05-26 Hybrigenics Sa Neue therapeutische Verwendungen von Inecalcitol
ES2437921T3 (es) * 2009-10-21 2014-01-15 Wisconsin Alumni Research Foundation Método para prevenir la diabetes tipo 1
US20120015913A1 (en) * 2010-07-15 2012-01-19 Delansorne Remi Formulations of 14-EPI-Analogues of Vitamin D
EP2407155B1 (en) 2010-07-15 2012-12-26 Hybrigenics S.A. Formulations of inecalcitol
EP2407152A1 (en) 2010-07-15 2012-01-18 Hybrigenics S.A. Formulations of 14-epi-analogues of vitamin D
EP2682386B1 (en) * 2011-03-02 2016-08-17 Nihon University Novel vitamin d receptor modulator with partial agonist activity
WO2016065042A1 (en) 2014-10-22 2016-04-28 Extend Biosciences, Inc. Therapeutic vitamin d conjugates
US9616109B2 (en) 2014-10-22 2017-04-11 Extend Biosciences, Inc. Insulin vitamin D conjugates
CN104326922B (zh) * 2014-11-03 2016-08-17 成都百裕制药股份有限公司 替格瑞洛中间体(1r,2s)-2-(2,3-二氟苯基)环丙胺的制备方法
KR20250075704A (ko) 2022-09-30 2025-05-28 익스텐드 바이오사이언시즈, 인크. 장기-지속형 부갑상선 호르몬

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4804502A (en) * 1988-01-20 1989-02-14 Hoffmann-La Roche Inc. Vitamin D compounds
PT972762E (pt) * 1993-07-09 2004-02-27 Theramex Novos analogos estruturais da vitamina d
US5936105A (en) * 1997-06-13 1999-08-10 Tetrionics, Inc. 14-EPI-19-nor-vitamin D compounds and methods
US6806262B2 (en) * 2000-05-31 2004-10-19 Wisconsin Alumni Research Foundation 2-ethyl and 2-ethylidene-19-nor-vitamin D compounds

Also Published As

Publication number Publication date
EP1601646B1 (en) 2011-07-27
JP2006519788A (ja) 2006-08-31
AU2004220477A1 (en) 2004-09-23
WO2004080922A3 (en) 2004-12-09
ES2368064T3 (es) 2011-11-14
ATE517864T1 (de) 2011-08-15
SI1601646T1 (sl) 2011-11-30
CA2518531A1 (en) 2004-09-23
PT1601646E (pt) 2011-09-16
US20060189576A1 (en) 2006-08-24
CY1111843T1 (el) 2015-10-07
DK1601646T3 (da) 2011-10-03
EP1601646A2 (en) 2005-12-07
AU2004220477B2 (en) 2010-05-06
AU2004220477B8 (en) 2010-10-14
WO2004080922A2 (en) 2004-09-23
GB0305332D0 (en) 2003-04-09

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