PL1620373T3 - Urządzenie i sposób fluorowania nukleofilowego - Google Patents

Urządzenie i sposób fluorowania nukleofilowego

Info

Publication number
PL1620373T3
PL1620373T3 PL04731136T PL04731136T PL1620373T3 PL 1620373 T3 PL1620373 T3 PL 1620373T3 PL 04731136 T PL04731136 T PL 04731136T PL 04731136 T PL04731136 T PL 04731136T PL 1620373 T3 PL1620373 T3 PL 1620373T3
Authority
PL
Poland
Prior art keywords
anion exchange
measurement
fluoride ions
exchange device
target fluid
Prior art date
Application number
PL04731136T
Other languages
English (en)
Inventor
Peter Maeding
Frank Fuechtner
Original Assignee
Bayer Schering Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10320552A external-priority patent/DE10320552A1/de
Application filed by Bayer Schering Pharma Ag filed Critical Bayer Schering Pharma Ag
Publication of PL1620373T3 publication Critical patent/PL1620373T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/041—Heterocyclic compounds
    • A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0459—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nuclear Medicine (AREA)
  • Saccharide Compounds (AREA)
PL04731136T 2003-05-07 2004-05-05 Urządzenie i sposób fluorowania nukleofilowego PL1620373T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE10320552A DE10320552A1 (de) 2003-05-07 2003-05-07 Vorrichtung und Verfahren zum nucleophilen Fluorieren
US46896303P 2003-05-09 2003-05-09
EP04731136A EP1620373B1 (de) 2003-05-07 2004-05-05 Vorrichtung und verfahren zum nucleophilen fluorieren
PCT/EP2004/004784 WO2004100490A2 (de) 2003-05-07 2004-05-05 Vorrichtung und verfahren zum nucleophilen fluorieren

Publications (1)

Publication Number Publication Date
PL1620373T3 true PL1620373T3 (pl) 2008-09-30

Family

ID=33435959

Family Applications (1)

Application Number Title Priority Date Filing Date
PL04731136T PL1620373T3 (pl) 2003-05-07 2004-05-05 Urządzenie i sposób fluorowania nukleofilowego

Country Status (11)

Country Link
US (1) US7482498B2 (pl)
EP (1) EP1620373B1 (pl)
JP (1) JP2006525279A (pl)
AT (1) ATE390395T1 (pl)
AU (1) AU2004237297B2 (pl)
DE (1) DE502004006670D1 (pl)
DK (1) DK1620373T3 (pl)
ES (1) ES2305769T3 (pl)
PL (1) PL1620373T3 (pl)
PT (1) PT1620373E (pl)
WO (1) WO2004100490A2 (pl)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2007292578B2 (en) * 2006-09-06 2012-11-29 Nihon Medi-Physics Co., Ltd. Process for producing radioactive fluorine labeled organic compound, and relevant synthetic apparatus and program
US8293208B2 (en) 2009-05-15 2012-10-23 The Governors Of The University Of Alberta Fluorinated fructose derivatives for PET imaging
WO2011044453A2 (en) * 2009-10-08 2011-04-14 Ge Healthcare Limited Multi-stream spectrophotometer module
WO2012092394A1 (en) 2010-12-29 2012-07-05 Cardinal Health 414, Llc Closed vial fill system for aseptic dispensing
KR101245790B1 (ko) * 2011-05-13 2013-03-20 성균관대학교산학협력단 방사성 화합물 합성장치
WO2013012822A1 (en) 2011-07-15 2013-01-24 Cardinal Health 414, Llc Systems, methods, and devices for producing, manufacturing, and control of radiopharmaceuticals
US9417332B2 (en) 2011-07-15 2016-08-16 Cardinal Health 414, Llc Radiopharmaceutical CZT sensor and apparatus
US20130023657A1 (en) * 2011-07-15 2013-01-24 Cardinal Health 414, Llc System for radiopharmaceutical preparation involving solid and liquid phase interactions
US20130020727A1 (en) 2011-07-15 2013-01-24 Cardinal Health 414, Llc. Modular cassette synthesis unit
EP2760808B1 (en) * 2011-09-30 2015-11-18 GE Healthcare Limited Calibration and normalization systems and methods for radiopharmaceutical synthesizers
CN102744346B (zh) * 2012-07-17 2014-04-23 济宁科力光电产业有限责任公司 安全光幕的动态自检方法
KR101276741B1 (ko) 2012-10-22 2013-06-19 성균관대학교산학협력단 방사성 화합물 합성장치
CN109806822B (zh) * 2019-01-30 2021-07-30 杭州吉蕊科技有限公司 一种模块化、多功能的pet探针自动化合成系统

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3424525A1 (de) * 1984-07-04 1986-01-16 Kernforschungsanlage Jülich GmbH, 5170 Jülich Verfahren zur herstellung von (pfeil hoch)1(pfeil hoch)(pfeil hoch)8(pfeil hoch)f-alkyl- und arylverbindungen durch halogenaustausch
US5932178A (en) * 1996-03-29 1999-08-03 Nkk Plant Engineering Corporation FDG synthesizer using columns
JP3133251B2 (ja) * 1996-03-29 2001-02-05 エヌケ−ケ−プラント建設株式会社 陽イオン交換樹脂カラム上で、溶媒除去と加水分解反応を同時に行うｆｄｇ合成装置
JP3133252B2 (ja) * 1996-03-29 2001-02-05 エヌケ−ケ−プラント建設株式会社 三方切り替え活栓を組み込んだｆｄｇ合成装置
JP3279914B2 (ja) * 1996-03-29 2002-04-30 エヌケ−ケ−プラント建設株式会社 オンカラムｆｄｇ合成装置
JPH11295494A (ja) * 1998-04-08 1999-10-29 Nippon Meji Physics Kk ［ｆ−１８］−フッ化物イオンの製造方法
UY27003A1 (es) * 2000-11-06 2002-07-31 Schering Ag Productos radiofarmacéuticos para el diagnóstico de la enfermedad de alzheimer
CA2450484C (en) * 2001-06-13 2008-11-04 Stefan K. Zeisler Apparatus and method for generating 18f-fluoride by ion beams
GB0305848D0 (en) * 2003-03-14 2003-04-16 Imaging Res Solutions Ltd Radiopharmaceutical generation system
CA2523189A1 (en) * 2003-04-22 2004-11-04 Molecular Technologies, Inc. System and method for synthesis of molecular imaging probes including fdg

Also Published As

Publication number Publication date
PT1620373E (pt) 2008-06-30
AU2004237297B2 (en) 2010-04-08
EP1620373A2 (de) 2006-02-01
ES2305769T3 (es) 2008-11-01
AU2004237297A1 (en) 2004-11-18
WO2004100490A2 (de) 2004-11-18
DK1620373T3 (da) 2008-07-28
WO2004100490A3 (de) 2005-05-26
JP2006525279A (ja) 2006-11-09
ATE390395T1 (de) 2008-04-15
US20090005617A1 (en) 2009-01-01
DE502004006670D1 (de) 2008-05-08
US7482498B2 (en) 2009-01-27
EP1620373B1 (de) 2008-03-26

Similar Documents

Publication Publication Date Title
PT1620373E (pt) Dispositivo e método de fluoração nucleofílica
HUP0400253A2 (hu) Szilárd fázisú nukleofil fluorozás
van der Meulen et al. Cyclotron production of 44Sc: From bench to bedside
Pruszyński et al. Post-elution processing of 44Ti/44Sc generator-derived 44Sc for clinical application
JP7427703B2 (ja) 放射線標識した前立腺特異的膜抗原（ＰＳＭＡ）阻害剤 ［１８Ｆ］ＤＣＦＰｙＬ の改良合成
Wilson et al. Evaluation of nitrogen-rich macrocyclic ligands for the chelation of therapeutic bismuth radioisotopes
Kersemans et al. Automated radiosynthesis of Al [18F] PSMA-11 for large scale routine use
Asti et al. Influence of cations on the complexation yield of DOTATATE with yttrium and lutetium: a perspective study for enhancing the 90Y and 177Lu labeling conditions
EA201892668A1 (ru) Tc-EDDA/HYNIC-iPSMA В КАЧЕСТВЕ РАДИОФАРМАЦЕВТИЧЕСКОГО ПРЕПАРАТА ДЛЯ ОБНАРУЖЕНИЯ СВЕРХЭКСПРЕССИИ ПРОСТАТСПЕЦИФИЧЕСКОГО МЕМБРАННОГО АНТИГЕНА
Martins et al. Spectroscopic, radiochemical, and theoretical studies of the Ga3+‐N‐2‐hydroxyethyl piperazine‐N′‐2‐ethanesulfonic acid (HEPES buffer) system: evidence for the formation of Ga3+‐HEPES complexes in 68 Ga labeling reactions
KR20160133451A (ko) 실시간 핵 동위체 검출
Breunig et al. Production of no-carrier-added radiobromine: new nickel selenide target and optimized separation by dry distillation.
Feng et al. Evaluation of 72Se/72As generator and production of 72Se for supplying 72As as a potential PET imaging radionuclide
Huclier-Markai et al. A comparative thermodynamic study of the formation of scandium complexes with DTPA and DOTA
Doyle et al. A practical guide for the preparation of C1-labeled α-amino acids using aldehyde catalysis with isotopically labeled CO2
Bigott et al. Advances in the production, processing and microPET image quality of technetium-94m
Ruangma et al. Three-dimensional maximum a posteriori (MAP) imaging with radiopharmaceuticals labeled with three Cu radionuclides
Chakravarty et al. Clinical 68Ga-PET: is radiosynthesis module an absolute necessity?
Garcia‐Arguello et al. Automated production of [68Ga] Ga‐DOTANOC and [68Ga] Ga‐PSMA‐11 using a TRACERlab FXFN synthesis module
JP6274689B1 (ja) Ｒｉ標識化合物製造装置及びｒｉ標識化合物製造方法
ATE439869T1 (de) Automatisches radioaktives markierungsverafhren
Szydlo et al. Synthesis and quality control of 68Ga-PSMA PET/CT tracer used in prostate cancer imaging and comparison with 18F-fluorocholine as a reference point
WO2009083530A3 (en) Fluoride processing method
AP Breeman et al. Alternative method to determine specific activity of 177Lu by HPLC
bin Ahmad Fadzil et al. Synthesis and clinical evaluation of cyclotron-produced [68Ga] PSMA-11 and [18F] PSMA-1007 for prostate cancer imaging