PL1636217T3 - 1-Imidazobenzotiazole jako ligandy receptora adenozynowego - Google Patents
1-Imidazobenzotiazole jako ligandy receptora adenozynowegoInfo
- Publication number
- PL1636217T3 PL1636217T3 PL04731369T PL04731369T PL1636217T3 PL 1636217 T3 PL1636217 T3 PL 1636217T3 PL 04731369 T PL04731369 T PL 04731369T PL 04731369 T PL04731369 T PL 04731369T PL 1636217 T3 PL1636217 T3 PL 1636217T3
- Authority
- PL
- Poland
- Prior art keywords
- sup
- benzothiazoles
- imidazo
- sub
- receptor ligands
- Prior art date
Links
- 102000009346 Adenosine receptors Human genes 0.000 title abstract 2
- 108050000203 Adenosine receptors Proteins 0.000 title abstract 2
- 239000003446 ligand Substances 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 102000005962 receptors Human genes 0.000 abstract 1
- 108020003175 receptors Proteins 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Addiction (AREA)
- Psychology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Transplantation (AREA)
- Anesthesiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Saccharide Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03009842 | 2003-05-13 | ||
| PCT/EP2004/004843 WO2004101558A1 (en) | 2003-05-13 | 2004-05-06 | 2-imidazo-benzothiazoles as adenosine receptor ligands |
| EP04731369A EP1636217B1 (en) | 2003-05-13 | 2004-05-06 | 2-imidazo-benzothiazoles as adenosine receptor ligands |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL1636217T3 true PL1636217T3 (pl) | 2009-02-27 |
Family
ID=33395778
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL04731369T PL1636217T3 (pl) | 2003-05-13 | 2004-05-06 | 1-Imidazobenzotiazole jako ligandy receptora adenozynowego |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US7122545B2 (pl) |
| EP (1) | EP1636217B1 (pl) |
| JP (1) | JP4408291B2 (pl) |
| KR (1) | KR100710453B1 (pl) |
| CN (1) | CN100372844C (pl) |
| AT (1) | ATE407133T1 (pl) |
| AU (1) | AU2004238508B2 (pl) |
| BR (1) | BRPI0410315A (pl) |
| CA (1) | CA2523959A1 (pl) |
| DE (1) | DE602004016328D1 (pl) |
| ES (1) | ES2313001T3 (pl) |
| MX (1) | MXPA05012120A (pl) |
| PL (1) | PL1636217T3 (pl) |
| RU (1) | RU2340612C2 (pl) |
| WO (1) | WO2004101558A1 (pl) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1909910A1 (en) * | 2005-08-04 | 2008-04-16 | Sirtris Pharmaceuticals, Inc. | Benzimidazole derivatives as sirtuin modulators |
| TW200736252A (en) * | 2006-01-27 | 2007-10-01 | Astrazeneca Ab | Novel heteroaryl substituted benzothiazoles |
| TW200813035A (en) | 2006-06-19 | 2008-03-16 | Astrazeneca Ab | Novel heteroaryl substituted benzoxazoles |
| TW200901998A (en) | 2007-03-06 | 2009-01-16 | Astrazeneca Ab | Novel 2-heteroaryl substituted benzothiophenes and benzofuranes |
| SG174125A1 (en) * | 2009-04-02 | 2011-10-28 | Merck Serono Sa | Dihydroorotate dehydrogenase inhibitors |
| US20120029190A1 (en) * | 2009-04-03 | 2012-02-02 | Douglas Burdi | Compounds for treating disorders mediated by metabotropic glutamate receptor 5, and methods of use thereof |
| US8575336B2 (en) | 2011-07-27 | 2013-11-05 | Pfizer Limited | Indazoles |
| WO2016164565A1 (en) * | 2015-04-08 | 2016-10-13 | University Of Delaware | Trans-cycloheptenes and hetero-trans-cycloheptenes for bioorthogonal coupling |
| WO2018193090A2 (en) * | 2017-04-21 | 2018-10-25 | Amneal Pharmaceuticals Company Gmbh | Process for preparation of eliglustat hemitartrate and intermediates thereof |
| CN110997662B (zh) | 2017-08-21 | 2023-10-31 | 默克专利股份公司 | 作为腺苷受体拮抗剂的苯并咪唑衍生物 |
| WO2025160629A1 (en) * | 2024-01-31 | 2025-08-07 | Certa Therapeutics Pty Ltd | Proton sensing gpcr modulators |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI91859C (fi) * | 1987-06-17 | 1994-08-25 | Eisai Co Ltd | Analogiamenetelmä antiallergisena aineena aktiivisen bentsotiatsolijohdannaisen valmistamiseksi |
| IL90337A0 (en) * | 1988-05-24 | 1989-12-15 | Pfizer | Aromatic and heterocyclic carboxamide derivatives as antineoplastic agents |
| IT1260444B (it) * | 1992-01-24 | 1996-04-09 | Mario Brufani | Derivati della 8-(1-amminocicloalchil)1,3-dialchilxantina, procedimenbto di preparazione e loro composizioni farmaceutiche antidepressive, nootropiche e psicostimolanti |
| US6037473A (en) * | 1997-11-13 | 2000-03-14 | Haarmann & Reimer Gmbh | Use of substituted benzazoles as UV absorbers, new benzazoles and processes for their preparation |
| DE60022366T2 (de) * | 1999-07-02 | 2006-06-14 | Eisai Co Ltd | Kondensierte imidazolderivate und arzneimittel gegen diabetes mellitus |
| NZ522928A (en) * | 2000-06-21 | 2005-05-27 | F | Benzothiazole derivatives |
| EP1628662B1 (en) * | 2003-05-21 | 2007-02-14 | F. Hoffmann-La Roche Ag | Benzothiazole derivatives and use thereof in the treatment of diseases related to the adenosine a2a receptor |
-
2004
- 2004-05-06 DE DE602004016328T patent/DE602004016328D1/de not_active Expired - Lifetime
- 2004-05-06 BR BRPI0410315-7A patent/BRPI0410315A/pt not_active IP Right Cessation
- 2004-05-06 JP JP2006529752A patent/JP4408291B2/ja not_active Expired - Fee Related
- 2004-05-06 EP EP04731369A patent/EP1636217B1/en not_active Expired - Lifetime
- 2004-05-06 ES ES04731369T patent/ES2313001T3/es not_active Expired - Lifetime
- 2004-05-06 RU RU2005138546/04A patent/RU2340612C2/ru not_active IP Right Cessation
- 2004-05-06 AT AT04731369T patent/ATE407133T1/de not_active IP Right Cessation
- 2004-05-06 CA CA002523959A patent/CA2523959A1/en not_active Abandoned
- 2004-05-06 KR KR1020057021535A patent/KR100710453B1/ko not_active Expired - Fee Related
- 2004-05-06 PL PL04731369T patent/PL1636217T3/pl unknown
- 2004-05-06 MX MXPA05012120A patent/MXPA05012120A/es active IP Right Grant
- 2004-05-06 CN CNB2004800117819A patent/CN100372844C/zh not_active Expired - Fee Related
- 2004-05-06 WO PCT/EP2004/004843 patent/WO2004101558A1/en not_active Ceased
- 2004-05-06 AU AU2004238508A patent/AU2004238508B2/en not_active Ceased
- 2004-05-11 US US10/843,241 patent/US7122545B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP1636217B1 (en) | 2008-09-03 |
| MXPA05012120A (es) | 2006-02-08 |
| CN100372844C (zh) | 2008-03-05 |
| DE602004016328D1 (de) | 2008-10-16 |
| EP1636217A1 (en) | 2006-03-22 |
| AU2004238508B2 (en) | 2009-11-19 |
| ATE407133T1 (de) | 2008-09-15 |
| BRPI0410315A (pt) | 2006-05-23 |
| US20040229862A1 (en) | 2004-11-18 |
| AU2004238508A1 (en) | 2004-11-25 |
| JP2006528215A (ja) | 2006-12-14 |
| WO2004101558A1 (en) | 2004-11-25 |
| US7122545B2 (en) | 2006-10-17 |
| KR20060009928A (ko) | 2006-02-01 |
| CA2523959A1 (en) | 2004-11-25 |
| ES2313001T3 (es) | 2009-03-01 |
| KR100710453B1 (ko) | 2007-04-24 |
| CN1780831A (zh) | 2006-05-31 |
| RU2005138546A (ru) | 2006-07-27 |
| RU2340612C2 (ru) | 2008-12-10 |
| JP4408291B2 (ja) | 2010-02-03 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| TW200505902A (en) | Cannabinoid receptor ligands | |
| NZ541974A (en) | Nucleotide phosphoramidates as anticancer agents | |
| MX2008000141A (es) | Moduladores de lxr basados en imidazol. | |
| WO2004026248A3 (en) | Octahydro-2-h-naphtho[1,2-f] indole-4-carboxamide derivatives as selective glucocorticoid receptor modulators | |
| IL161074A0 (en) | Lactam derivatives as antagonists for human 11cby receptors | |
| IL155875A0 (en) | Piperazinylpyrazines compounds as antagonists of serotonin 5-ht2 receptor | |
| MXPA05009367A (es) | Antagonistas del receptor opioide. | |
| UA94833C2 (en) | Substituted bicyclolactams | |
| GEP20115174B (en) | Triazolopyrazine derivatives useful as anti-cancer agents | |
| CZ305838B6 (cs) | N-(2-arylethyl)benzylaminy jako antagonisté receptoru 5-HT6 | |
| YU80902A (sh) | Novi indolin-2-on derivati, njihovo dobijanje i farmaceuski oblici koji ih sadrže | |
| MXPA05013474A (es) | Derivados de quinolilamida como antagonistas de ccr-5. | |
| TW200517388A (en) | Thiazole derivatives as cannabinoid receptor modulators | |
| EA200400467A1 (ru) | Производные 3-азабицикло (3.1.0) гексана в качестве антагонистов опиоидного рецептора | |
| ATE374190T1 (de) | Tetrahydrochinazolinderivate als cfr-antagonisten | |
| EA200401455A1 (ru) | Производные бензоксазина в качестве модуляторов 5-htи их применение | |
| AU2003239389A1 (en) | Opioid receptor antagonists | |
| WO2005060959A8 (en) | Pyrazole derivatives and use thereof as orexin receptor antagonists | |
| ATE407133T1 (de) | 2-imidazo-benzothiazole als adenosin-rezeptor liganden | |
| MY138826A (en) | 2,7-substituted indoles | |
| WO2004112704A3 (en) | Substituted piperidine compounds and methods of their use | |
| WO2000073269A3 (en) | Nicotine receptor ligands | |
| MXPA05005198A (es) | Derivados de imidazoquinolina, como ligandos del receptor a3 de adenosina. | |
| MXPA04006113A (es) | Derivados de triazoloquinolina utiles como ligandos receptores de adenosina. | |
| MXPA04005988A (es) | 3,4-dihidro-1h-isoquinolin-2-il-derivados. |