PL1718340T3 - Nowe koniugaty efektorowe, sposób ich wytwarzania i ich zastosowanie farmaceutyczne - Google Patents
Nowe koniugaty efektorowe, sposób ich wytwarzania i ich zastosowanie farmaceutyczneInfo
- Publication number
- PL1718340T3 PL1718340T3 PL05707090T PL05707090T PL1718340T3 PL 1718340 T3 PL1718340 T3 PL 1718340T3 PL 05707090 T PL05707090 T PL 05707090T PL 05707090 T PL05707090 T PL 05707090T PL 1718340 T3 PL1718340 T3 PL 1718340T3
- Authority
- PL
- Poland
- Prior art keywords
- production
- pharmaceutical use
- new effector
- effector conjugates
- conjugates
- Prior art date
Links
- 239000012636 effector Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6849—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a receptor, a cell surface antigen or a cell surface determinant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Ophthalmology & Optometry (AREA)
- Hospice & Palliative Care (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Oncology (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychiatry (AREA)
- Cell Biology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US53997704P | 2004-01-30 | 2004-01-30 | |
| DE102004004787A DE102004004787A1 (de) | 2004-01-30 | 2004-01-30 | Neue Effektor-Konjugate, Verfahren zu ihrer Herstellung und ihre pharmazeutische Verwendung |
| EP05707090A EP1718340B1 (en) | 2004-01-30 | 2005-01-31 | New effector conjugates, process for their production and their pharmaceutical use |
| PCT/EP2005/000917 WO2005074901A2 (en) | 2004-01-30 | 2005-01-31 | New effector conjugates, process for their production and their pharmaceutical use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL1718340T3 true PL1718340T3 (pl) | 2008-04-30 |
Family
ID=34839581
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL05707090T PL1718340T3 (pl) | 2004-01-30 | 2005-01-31 | Nowe koniugaty efektorowe, sposób ich wytwarzania i ich zastosowanie farmaceutyczne |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP1718340B1 (pl) |
| JP (1) | JP2007519681A (pl) |
| CY (1) | CY1107207T1 (pl) |
| DE (1) | DE602005003453T2 (pl) |
| DK (1) | DK1718340T3 (pl) |
| ES (1) | ES2296133T3 (pl) |
| PL (1) | PL1718340T3 (pl) |
| PT (1) | PT1718340E (pl) |
| SI (1) | SI1718340T1 (pl) |
| WO (1) | WO2005074901A2 (pl) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101098854B (zh) | 2004-07-23 | 2012-12-05 | 恩多塞特公司 | 二价连接体及其轭合物 |
| PE20080316A1 (es) | 2006-05-25 | 2008-04-10 | Bristol Myers Squibb Co | Compuestos de aziridinil-epotilona |
| AU2008224988A1 (en) | 2007-03-14 | 2008-09-18 | Endocyte, Inc. | Binding ligand linked drug delivery conjugates of tubulysins |
| EP2152717A1 (en) | 2007-05-25 | 2010-02-17 | Bristol-Myers Squibb Company | Processes for making epothilone compounds and analogs |
| WO2009000406A1 (en) * | 2007-06-22 | 2008-12-31 | Bayer Healthcare Ag | Use of antibodies against the cd52 antigen for the treatment of neurological disorders, particularly transmissible spongiform encephalopathy and alzheimer's disease |
| CN101784565B (zh) | 2007-06-25 | 2014-12-10 | 恩多塞特公司 | 含有亲水性间隔区接头的共轭物 |
| US9877965B2 (en) | 2007-06-25 | 2018-01-30 | Endocyte, Inc. | Vitamin receptor drug delivery conjugates for treating inflammation |
| CN101909441B (zh) | 2007-10-25 | 2015-05-13 | 恩多塞特公司 | 微管蛋白抑制剂及其制备方法 |
| US10080805B2 (en) | 2012-02-24 | 2018-09-25 | Purdue Research Foundation | Cholecystokinin B receptor targeting for imaging and therapy |
| US20140080175A1 (en) | 2012-03-29 | 2014-03-20 | Endocyte, Inc. | Processes for preparing tubulysin derivatives and conjugates thereof |
| BR112015008365A2 (pt) | 2012-10-16 | 2017-07-04 | Endocyte Inc | composto da fórmula b-l(d)x, ou um sal farmaceuticamente aceitável do mesmo, composição farmacêutica, uso de um composto, composição de forma de dosagem unitária ou dose unitária, composição para tratar um câncer em um paciente, e método para tratar um câncer em um paciente |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10234975A1 (de) * | 2002-07-31 | 2004-02-12 | Schering Ag | Neue Effektor-Konjugate, Verfahren zu ihrer Herstellung und ihre pharmazeutische Verwendung |
| DE10305098A1 (de) * | 2003-02-07 | 2004-08-19 | Schering Ag | Neue Effektor-Konjugate, Verfahren zu ihrer Herstellung und ihre pharmazeutische Verwendung |
| BR0313043A (pt) * | 2002-07-31 | 2005-06-14 | Schering Ag | Conjugados efetores, processo para sua produção e seu uso farmacêutico |
| US20040126379A1 (en) * | 2002-08-21 | 2004-07-01 | Boehringer Ingelheim International Gmbh | Compositions and methods for treating cancer using cytotoxic CD44 antibody immunoconjugates and chemotherapeutic agents |
| DE10256982A1 (de) * | 2002-12-05 | 2004-06-24 | Schering Ag | Neue Effektor-Konjugate, Verfahren zu Ihrer Herstellung und Ihre Pharmazeutische Verwendung |
| JP2006510626A (ja) * | 2002-12-05 | 2006-03-30 | シエーリング アクチエンゲゼルシャフト | 増殖疾患の処理における部位特異的供給のためのエポチロン類似体 |
-
2005
- 2005-01-31 DK DK05707090T patent/DK1718340T3/da active
- 2005-01-31 DE DE602005003453T patent/DE602005003453T2/de not_active Expired - Fee Related
- 2005-01-31 PT PT05707090T patent/PT1718340E/pt unknown
- 2005-01-31 PL PL05707090T patent/PL1718340T3/pl unknown
- 2005-01-31 ES ES05707090T patent/ES2296133T3/es not_active Expired - Lifetime
- 2005-01-31 EP EP05707090A patent/EP1718340B1/en not_active Expired - Lifetime
- 2005-01-31 SI SI200530139T patent/SI1718340T1/sl unknown
- 2005-01-31 WO PCT/EP2005/000917 patent/WO2005074901A2/en not_active Ceased
- 2005-01-31 JP JP2006550125A patent/JP2007519681A/ja not_active Withdrawn
-
2008
- 2008-02-21 CY CY20081100203T patent/CY1107207T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005074901A2 (en) | 2005-08-18 |
| ES2296133T3 (es) | 2008-04-16 |
| PT1718340E (pt) | 2008-02-07 |
| EP1718340A2 (en) | 2006-11-08 |
| DK1718340T3 (da) | 2008-03-03 |
| SI1718340T1 (sl) | 2008-04-30 |
| JP2007519681A (ja) | 2007-07-19 |
| EP1718340B1 (en) | 2007-11-21 |
| DE602005003453T2 (de) | 2008-09-25 |
| WO2005074901A3 (en) | 2006-03-30 |
| DE602005003453D1 (de) | 2008-01-03 |
| CY1107207T1 (el) | 2012-11-21 |
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