PL1718340T3 - Nowe koniugaty efektorowe, sposób ich wytwarzania i ich zastosowanie farmaceutyczne - Google Patents
Nowe koniugaty efektorowe, sposób ich wytwarzania i ich zastosowanie farmaceutyczneInfo
- Publication number
- PL1718340T3 PL1718340T3 PL05707090T PL05707090T PL1718340T3 PL 1718340 T3 PL1718340 T3 PL 1718340T3 PL 05707090 T PL05707090 T PL 05707090T PL 05707090 T PL05707090 T PL 05707090T PL 1718340 T3 PL1718340 T3 PL 1718340T3
- Authority
- PL
- Poland
- Prior art keywords
- production
- pharmaceutical use
- new effector
- effector conjugates
- conjugates
- Prior art date
Links
- 239000012636 effector Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6849—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a receptor, a cell surface antigen or a cell surface determinant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Ophthalmology & Optometry (AREA)
- Rheumatology (AREA)
- Cell Biology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US53997704P | 2004-01-30 | 2004-01-30 | |
| DE102004004787A DE102004004787A1 (de) | 2004-01-30 | 2004-01-30 | Neue Effektor-Konjugate, Verfahren zu ihrer Herstellung und ihre pharmazeutische Verwendung |
| EP05707090A EP1718340B1 (en) | 2004-01-30 | 2005-01-31 | New effector conjugates, process for their production and their pharmaceutical use |
| PCT/EP2005/000917 WO2005074901A2 (en) | 2004-01-30 | 2005-01-31 | New effector conjugates, process for their production and their pharmaceutical use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL1718340T3 true PL1718340T3 (pl) | 2008-04-30 |
Family
ID=34839581
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL05707090T PL1718340T3 (pl) | 2004-01-30 | 2005-01-31 | Nowe koniugaty efektorowe, sposób ich wytwarzania i ich zastosowanie farmaceutyczne |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP1718340B1 (pl) |
| JP (1) | JP2007519681A (pl) |
| CY (1) | CY1107207T1 (pl) |
| DE (1) | DE602005003453T2 (pl) |
| DK (1) | DK1718340T3 (pl) |
| ES (1) | ES2296133T3 (pl) |
| PL (1) | PL1718340T3 (pl) |
| PT (1) | PT1718340E (pl) |
| SI (1) | SI1718340T1 (pl) |
| WO (1) | WO2005074901A2 (pl) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8288557B2 (en) | 2004-07-23 | 2012-10-16 | Endocyte, Inc. | Bivalent linkers and conjugates thereof |
| AR061181A1 (es) | 2006-05-25 | 2008-08-13 | Bristol Myers Squibb Co | Compuestos de aziridinil-epotilona |
| CN101678124A (zh) | 2007-03-14 | 2010-03-24 | 恩多塞特公司 | 结合配体连接的微管溶素递药缀合物 |
| CN101754969A (zh) | 2007-05-25 | 2010-06-23 | 百时美施贵宝公司 | 制备埃坡霉素化合物和类似物的方法 |
| US20100178293A1 (en) * | 2007-06-22 | 2010-07-15 | Olaf Weber | Use of antibodies against the cd52 antigen for the treatment of neurological disorders, particularly transmissible spongiform encephalopathy and alzheimer's disease |
| CN101784565B (zh) | 2007-06-25 | 2014-12-10 | 恩多塞特公司 | 含有亲水性间隔区接头的共轭物 |
| US9877965B2 (en) | 2007-06-25 | 2018-01-30 | Endocyte, Inc. | Vitamin receptor drug delivery conjugates for treating inflammation |
| CA2703491C (en) | 2007-10-25 | 2017-06-13 | Endocyte, Inc. | Tubulysins and processes for preparing |
| WO2013126797A1 (en) | 2012-02-24 | 2013-08-29 | Purdue Research Foundation | Cholecystokinin b receptor targeting for imaging and therapy |
| US20140080175A1 (en) | 2012-03-29 | 2014-03-20 | Endocyte, Inc. | Processes for preparing tubulysin derivatives and conjugates thereof |
| AU2013331440A1 (en) | 2012-10-16 | 2015-04-30 | Endocyte, Inc. | Drug delivery conjugates containing unnatural amino acids and methods for using |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10234975A1 (de) * | 2002-07-31 | 2004-02-12 | Schering Ag | Neue Effektor-Konjugate, Verfahren zu ihrer Herstellung und ihre pharmazeutische Verwendung |
| DE10305098A1 (de) * | 2003-02-07 | 2004-08-19 | Schering Ag | Neue Effektor-Konjugate, Verfahren zu ihrer Herstellung und ihre pharmazeutische Verwendung |
| WO2004012735A2 (en) * | 2002-07-31 | 2004-02-12 | Schering Ag | New effector conjugates, process for their production and their pharmaceutical use |
| US20040126379A1 (en) * | 2002-08-21 | 2004-07-01 | Boehringer Ingelheim International Gmbh | Compositions and methods for treating cancer using cytotoxic CD44 antibody immunoconjugates and chemotherapeutic agents |
| DE10256982A1 (de) * | 2002-12-05 | 2004-06-24 | Schering Ag | Neue Effektor-Konjugate, Verfahren zu Ihrer Herstellung und Ihre Pharmazeutische Verwendung |
| JP2006510626A (ja) * | 2002-12-05 | 2006-03-30 | シエーリング アクチエンゲゼルシャフト | 増殖疾患の処理における部位特異的供給のためのエポチロン類似体 |
-
2005
- 2005-01-31 DK DK05707090T patent/DK1718340T3/da active
- 2005-01-31 DE DE602005003453T patent/DE602005003453T2/de not_active Expired - Fee Related
- 2005-01-31 PT PT05707090T patent/PT1718340E/pt unknown
- 2005-01-31 EP EP05707090A patent/EP1718340B1/en not_active Expired - Lifetime
- 2005-01-31 PL PL05707090T patent/PL1718340T3/pl unknown
- 2005-01-31 WO PCT/EP2005/000917 patent/WO2005074901A2/en not_active Ceased
- 2005-01-31 SI SI200530139T patent/SI1718340T1/sl unknown
- 2005-01-31 JP JP2006550125A patent/JP2007519681A/ja not_active Withdrawn
- 2005-01-31 ES ES05707090T patent/ES2296133T3/es not_active Expired - Lifetime
-
2008
- 2008-02-21 CY CY20081100203T patent/CY1107207T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CY1107207T1 (el) | 2012-11-21 |
| DE602005003453D1 (de) | 2008-01-03 |
| WO2005074901A3 (en) | 2006-03-30 |
| PT1718340E (pt) | 2008-02-07 |
| JP2007519681A (ja) | 2007-07-19 |
| DE602005003453T2 (de) | 2008-09-25 |
| EP1718340B1 (en) | 2007-11-21 |
| DK1718340T3 (da) | 2008-03-03 |
| WO2005074901A2 (en) | 2005-08-18 |
| SI1718340T1 (sl) | 2008-04-30 |
| ES2296133T3 (es) | 2008-04-16 |
| EP1718340A2 (en) | 2006-11-08 |
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