PL1729739T3 - Sposób wytwarzania stałej kompozycji farmaceutycznej - Google Patents

Sposób wytwarzania stałej kompozycji farmaceutycznej

Info

Publication number
PL1729739T3
PL1729739T3 PL05730288T PL05730288T PL1729739T3 PL 1729739 T3 PL1729739 T3 PL 1729739T3 PL 05730288 T PL05730288 T PL 05730288T PL 05730288 T PL05730288 T PL 05730288T PL 1729739 T3 PL1729739 T3 PL 1729739T3
Authority
PL
Poland
Prior art keywords
preparing
pharmaceutical composition
solid pharmaceutical
solid
composition
Prior art date
Application number
PL05730288T
Other languages
English (en)
Inventor
Iztok Klobcar
Alesa Puncuh-Kolar
Anica Grandovec
Urska Turk
Polona Solmajer-Lampic
Original Assignee
Les Laboratoires Servier
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34963866&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL1729739(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DE200410019845 external-priority patent/DE102004019845A1/de
Priority claimed from DE102004059521A external-priority patent/DE102004059521A1/de
Application filed by Les Laboratoires Servier filed Critical Les Laboratoires Servier
Publication of PL1729739T3 publication Critical patent/PL1729739T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Indole Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
PL05730288T 2004-03-29 2005-03-29 Sposób wytwarzania stałej kompozycji farmaceutycznej PL1729739T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE200410019845 DE102004019845A1 (de) 2004-03-29 2004-03-29 Verfahren zur Herstellung einer festen pharmazeutischen Zusammensetzung
DE102004059521A DE102004059521A1 (de) 2004-12-09 2004-12-09 Verfahren zur Herstellung einer festen pharmazeutischen Zusammensetzung
EP05730288.7A EP1729739B1 (en) 2004-03-29 2005-03-29 Process for preparing a solid pharmaceutical composition

Publications (1)

Publication Number Publication Date
PL1729739T3 true PL1729739T3 (pl) 2017-04-28

Family

ID=34963866

Family Applications (1)

Application Number Title Priority Date Filing Date
PL05730288T PL1729739T3 (pl) 2004-03-29 2005-03-29 Sposób wytwarzania stałej kompozycji farmaceutycznej

Country Status (14)

Country Link
US (2) US20070172524A1 (pl)
EP (1) EP1729739B1 (pl)
JP (1) JP4948392B2 (pl)
CY (1) CY1118180T1 (pl)
DK (1) DK1729739T3 (pl)
EA (1) EA011712B1 (pl)
ES (1) ES2603856T3 (pl)
HR (1) HRP20161602T1 (pl)
HU (1) HUE031058T2 (pl)
LT (1) LT1729739T (pl)
NO (1) NO20064934L (pl)
PL (1) PL1729739T3 (pl)
PT (1) PT1729739T (pl)
WO (1) WO2005094793A1 (pl)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1729739T (pt) 2004-03-29 2016-12-01 Servier Lab Processo para a preparação de uma composição farmacêutica sólida
SI21800A (sl) * 2004-05-14 2005-12-31 Krka, Tovarna Zdravil, D.D., Novo Mesto Nov postopek sinteze perindoprila
BRPI0615607A2 (pt) * 2005-08-30 2011-05-24 Lek Pharmaceuticals composição farmacêutica compreendendo perindopril ou seus sais
RS53324B (sr) * 2005-11-17 2014-10-31 Silverstone Pharma Est. Stabilna formulacija amorfnih soli perindoprila, postupak za njihovu pripremu, naročito industrijsku pripremu, i njihova upotreba u terapiji hipertenzije
EP1815857A1 (en) 2006-02-02 2007-08-08 LEK Pharmaceuticals D.D. A pharmaceutical composition comprising perindopril
WO2007120930A2 (en) * 2006-04-19 2007-10-25 Teva Pharmaceutical Industries Ltd. Stable pharmaceutical compositions of 2-aza-bicyclo[3.3.0]-octane-3-carboxylic acid derivatives
JP2009537538A (ja) * 2006-05-15 2009-10-29 アカドイア プハルマセウチカルス インコーポレーテッド ピマバンセリン医薬製剤
WO2008068577A2 (en) * 2006-12-01 2008-06-12 Glenmark Pharmaceuticals Limited Pharmaceutical compositions
TWI435917B (zh) 2006-12-27 2014-05-01 Fujifilm Corp 顏料分散組成物、硬化性組成物、彩色濾光片及其製造方法
CA2676444C (en) * 2007-01-18 2013-07-30 Evolva Sa Prodrugs of substituted 1,3-dioxanes and their uses
SI22543A (sl) 2007-06-27 2008-12-31 Krka, Tovarna Zdravil, D.D., Novo Mesto Nove soli perindoprila
WO2011087629A2 (en) * 2009-12-22 2011-07-21 Fmc Corporation Microcrystalline cellulose and calcium carbonate compositions useful as recompactible pharmaceutical excipients
PL227900B1 (pl) 2012-11-15 2018-01-31 Adamed Spolka Z Ograniczona Odpowiedzialnoscia Kompozycja farmaceutyczna zawierająca inhibitor ACE i bloker kanałów wapniowych, sposób jej wytwarzania i jednostka dawkowania zawierająca tę kompozycję
WO2016178591A2 (en) 2015-05-05 2016-11-10 Gene Predit, Sa Genetic markers and treatment of male obesity
CN109700774A (zh) * 2019-03-05 2019-05-03 上药东英（江苏）药业有限公司 一种培哚普利叔丁胺片及其粉末直压工艺

Family Cites Families (39)

* Cited by examiner, † Cited by third party
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US4508729A (en) * 1979-12-07 1985-04-02 Adir Substituted iminodiacids, their preparation and pharmaceutical compositions containing them
US4350704A (en) * 1980-10-06 1982-09-21 Warner-Lambert Company Substituted acyl derivatives of octahydro-1H-indole-2-carboxylic acids
US4425355A (en) * 1981-02-17 1984-01-10 Warner-Lambert Company Substituted acyl derivatives of chair form of octahydro-1H-indole-2-carboxylic acids
US4743450A (en) * 1987-02-24 1988-05-10 Warner-Lambert Company Stabilized compositions
FR2620703B1 (fr) * 1987-09-17 1991-10-04 Adir Procede de synthese industrielle de l'acide perhydroindole carboxylique - 2(2s, 3as, 7as). application a la synthese de carboxyalkyl dipeptides
FR2620709B1 (fr) * 1987-09-17 1990-09-07 Adir Procede de synthese industrielle du perindopril et de ses principaux intermediaires de synthese
FR2620699B1 (fr) * 1987-09-17 1990-06-01 Adir Procede de synthese d'alpha amino acides n alkyles et de leurs esters. application a la synthese de carboxyalkyl dipeptides
US5258525A (en) * 1991-03-27 1993-11-02 Mcneilab, Inc. Processes for preparing [2S-(2α,3aβ,7aβ)]octahydro-1H-indole-2-carboxylic acid and esters
SI9111842A (sl) * 1991-11-25 1998-04-30 Krka Stabilna formulacija soli enalaprila, postopek za njeno pripravo in njena uporaba
FR2771010B1 (fr) * 1997-11-19 2003-08-15 Adir Utilisation d'une combinaison d'un inhibiteur de l'enzyme de conversion de l'angiotensine et d'un diuretique pour le traitement des desordres microcirculatoires
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FR2807037B1 (fr) * 2000-03-31 2002-05-10 Adir NOUVEAU PROCEDE DE SYNTHESE DES ESTERS DE LA N-[(s)-1- CARBOXYBUTYL]-(S)-ALANINE ET APPLICATION A LA SYNTHESE DU PERINDOPRIL
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FR2811319B1 (fr) * 2000-07-06 2002-08-23 Adir Nouvelle forme cristalline beta du sel de tert-butylamine du perindopril, son procede de preparation et les compositions pharmaceutiques qui la contiennent
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DE10038364A1 (de) 2000-08-05 2002-05-02 Hexal Ag Pharmazeutische, Ramipril enthaltende Brauseformulierung
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ATE365714T1 (de) * 2002-01-30 2007-07-15 Servier Lab Verfahren zur herstellung von hochreinem perindopril und zwischenverbindungen nützlich in der synthese
AU2003217916A1 (en) * 2002-03-08 2003-09-22 Teva Pharmeceuticals Usa, Inc. Stable formulations of angiotensin converting enzyme (ace) inhibitors
FR2838648B1 (fr) 2002-04-18 2004-05-21 Servier Lab Nouveau sel de perindopril et les compositions pharmaceutiques qui le contiennent
CA2488498A1 (en) * 2002-06-10 2003-12-18 Elan Pharma International Limited Nanoparticulate polycosanol formulations and novel polycosanol combinations
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ATE307801T1 (de) * 2003-02-28 2005-11-15 Servier Lab Verfahren zur synthese des (2s,3as,7as)- perhydroindol-2-carbonsäures und seiner estern, verwendung in der synthese von perindopril
EP1603558B1 (en) * 2003-02-28 2008-05-21 Les Laboratoires Servier S.A. Process for preparation of perindopril and salts thereof
CA2530788C (en) * 2003-06-26 2010-02-09 Teva Pharmaceutical Industries Ltd Stable pharmaceutical compositions of 2-aza-bicyclo[3.3.0]-octane-3-carboxylic acid derivatives
US6869963B2 (en) * 2003-07-11 2005-03-22 Sandoz Ag Stable pharmaceutical compositions containing an ACE inhibitor
GB2404336A (en) * 2003-07-30 2005-02-02 Cipla Ltd Stabilisation of therapeutic agents using a carbonate salt of an amino acid, preferably in the presence of a saccharide, & pharmaceutical compositions thereof
DE60329648D1 (de) * 2003-09-01 2009-11-26 Servier Lab Neues Verfahren zur Herstellung von Estern des N-((S)-1-Carboxybutyl)-(S)-alanins und seine Verwendung in der Synthese von Perindopril
GB2394660A (en) * 2003-12-17 2004-05-05 Niche Generics Ltd Stabilisation of pharmaceutical compositions comprising ACE inhibitor by absence of acidic excipients having large specific surface area, eg silicon dioxide
PT1729739T (pt) 2004-03-29 2016-12-01 Servier Lab Processo para a preparação de uma composição farmacêutica sólida
SI21800A (sl) * 2004-05-14 2005-12-31 Krka, Tovarna Zdravil, D.D., Novo Mesto Nov postopek sinteze perindoprila

Also Published As

Publication number Publication date
EA200601608A1 (ru) 2007-02-27
EP1729739A1 (en) 2006-12-13
ES2603856T3 (es) 2017-03-01
DK1729739T3 (en) 2016-10-31
US20070172524A1 (en) 2007-07-26
LT1729739T (lt) 2016-11-10
PT1729739T (pt) 2016-12-01
EA011712B1 (ru) 2009-04-28
WO2005094793A1 (en) 2005-10-13
HUE031058T2 (en) 2017-06-28
JP2007530623A (ja) 2007-11-01
JP4948392B2 (ja) 2012-06-06
EP1729739B1 (en) 2016-09-28
HRP20161602T1 (hr) 2016-12-30
CY1118180T1 (el) 2017-06-28
US20100172995A1 (en) 2010-07-08
NO20064934L (no) 2006-10-27

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