PL1758986T3 - Nerwowe komórki macierzyste - Google Patents
Nerwowe komórki macierzysteInfo
- Publication number
- PL1758986T3 PL1758986T3 PL05752405T PL05752405T PL1758986T3 PL 1758986 T3 PL1758986 T3 PL 1758986T3 PL 05752405 T PL05752405 T PL 05752405T PL 05752405 T PL05752405 T PL 05752405T PL 1758986 T3 PL1758986 T3 PL 1758986T3
- Authority
- PL
- Poland
- Prior art keywords
- stem cells
- neural stem
- neural
- cells
- stem
- Prior art date
Links
- 210000001178 neural stem cell Anatomy 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0623—Stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/11—Epidermal growth factor [EGF]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins
- C12N2533/52—Fibronectin; Laminin
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Developmental Biology & Embryology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Psychology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0412887.2A GB0412887D0 (en) | 2004-06-09 | 2004-06-09 | Control of neural stem cells |
| GBGB0503044.0A GB0503044D0 (en) | 2004-06-09 | 2005-02-14 | Neural stem cells |
| GBGB0505510.8A GB0505510D0 (en) | 2004-06-09 | 2005-03-17 | Neural stem cells |
| PCT/GB2005/002289 WO2005121318A2 (en) | 2004-06-09 | 2005-06-09 | Neural stem cells |
| EP05752405.0A EP1758986B1 (en) | 2004-06-09 | 2005-06-09 | Neural stem cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL1758986T3 true PL1758986T3 (pl) | 2016-03-31 |
Family
ID=34864834
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL05752405T PL1758986T3 (pl) | 2004-06-09 | 2005-06-09 | Nerwowe komórki macierzyste |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US8785187B2 (pl) |
| EP (2) | EP1758986B1 (pl) |
| JP (2) | JP2008501356A (pl) |
| CN (1) | CN103146649B (pl) |
| AU (1) | AU2005252434B2 (pl) |
| CA (1) | CA2569978C (pl) |
| DK (1) | DK1758986T3 (pl) |
| ES (1) | ES2557772T3 (pl) |
| GB (1) | GB2414995B (pl) |
| IL (1) | IL179919A (pl) |
| NZ (1) | NZ551832A (pl) |
| PL (1) | PL1758986T3 (pl) |
| WO (1) | WO2005121318A2 (pl) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2414995B (en) | 2004-06-09 | 2006-11-15 | Univ Edinburgh | Neural stem cells |
| US8492148B2 (en) * | 2005-02-23 | 2013-07-23 | Foundation For Biomedical Research & Innovation | Method for amplification of endothelial progenitor cell in vitro |
| KR100838013B1 (ko) * | 2006-06-07 | 2008-06-12 | 제일약품주식회사 | 인간배아줄기세포로부터 단계적 선별법을 통해 고수율로신경전구세포, 신경세포 및 기능성 도파민신경세포를생성하는 방법 |
| WO2008031451A1 (en) * | 2006-09-11 | 2008-03-20 | Institut Für Molekulare Diagnostik Und Innovative Therapie - Molthera - Gmbh | A post-natal periodontal-derived neural stem cell |
| WO2008068589A2 (en) * | 2006-12-05 | 2008-06-12 | Dialectica S.R.L. | Neural stem cell medium and differentiation method |
| EP1930412A1 (en) * | 2006-12-05 | 2008-06-11 | Dialectica s.r.l. | Neural stem cell medium and differentiation method |
| EP2128245A1 (en) * | 2008-05-27 | 2009-12-02 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Generation of induced pluripotent stem (iPS) cells |
| CN102325878A (zh) | 2008-12-23 | 2012-01-18 | 斯特姆塞尔思加利福尼亚有限公司 | 少突胶质前体细胞的靶向细胞群及制备与使用方法 |
| EP2270043A1 (en) * | 2009-07-03 | 2011-01-05 | Sanofi-Aventis | Extracellular allosteric inhibitor binding domain from a tyrosine kinase receptor |
| US8815581B2 (en) | 2010-02-03 | 2014-08-26 | Samsung Life Public Welfare Foundation | Method for proliferating stem cells by activating c-MET/HGF signaling and notch signaling |
| ES2616289T3 (es) * | 2012-03-01 | 2017-06-12 | Miltenyi Biotec Gmbh | Separación de neuronas vivas intactas |
| JP6450673B2 (ja) | 2012-04-03 | 2019-01-09 | リニューロン・リミテッドReNeuron Limited | 幹細胞微粒子 |
| GB201302468D0 (en) | 2013-02-12 | 2013-03-27 | Reneuron Ltd | Stem cell product |
| JP2015529450A (ja) | 2012-07-19 | 2015-10-08 | リニューロン・リミテッドReNeuron Limited | 幹細胞微粒子 |
| US9566310B2 (en) | 2012-09-10 | 2017-02-14 | Board Of Regents Of The Nevada System Of Higher Education On Behalf Of The University Of Nevada, Reno | Methods of treating muscular dystrophy |
| CN105142646A (zh) | 2013-02-12 | 2015-12-09 | 兰诺龙有限公司 | 产生微粒的方法 |
| JP2016516051A (ja) | 2013-03-15 | 2016-06-02 | ボード オブ リージェンツ オブ ザ ネヴァダ システム オブ ハイヤー エデュケーション オン ビハーフ オブ ザ ユニヴァーシティー オブ ネヴァダ リノ | 筋ジストロフィーを治療する方法 |
| US9738925B2 (en) * | 2013-03-15 | 2017-08-22 | Lyle J. Arnold | Methods for immobilizing target nucleic acids utilizing combinatorial capture probes |
| CN105246494B (zh) * | 2013-04-19 | 2020-02-07 | 高丽大学校产学协力团 | 刺激毛发生长或防止毛发脱落的包括神经干细胞的提取物的组合物及其制造方法 |
| GB201317887D0 (en) | 2013-10-09 | 2013-11-20 | Reneuron Ltd | Product |
| GB201317889D0 (en) | 2013-10-09 | 2013-11-20 | Reneuron Ltd | Product and use |
| KR101542847B1 (ko) * | 2013-11-01 | 2015-08-10 | 주식회사 비비에이치씨 | 중간엽 줄기세포로부터 유도된 만능 줄기세포를 이용하여 신경세포로 분화시키는 방법 |
| CN105624116B (zh) * | 2014-11-07 | 2020-04-07 | 中国科学院上海生命科学研究院 | 利用多能干细胞制备神经前体细胞的方法 |
| JP6782241B2 (ja) | 2015-01-12 | 2020-11-11 | ウェイク・フォレスト・ユニヴァーシティ・ヘルス・サイエンシズ | 多層皮膚代替製品、ならびにそれを作製および使用する方法 |
| CA2978109A1 (en) | 2015-03-31 | 2016-10-06 | The University Of North Carolina At Chapel Hill | Delivery vehicles for stem cells and uses thereof |
| US20190249147A1 (en) * | 2016-06-20 | 2019-08-15 | The Board Of Trustees Of The Leland Stanford Junior University | Biologically relevant in vitro screening of human neurons |
| US10751825B2 (en) | 2016-10-28 | 2020-08-25 | Illinois Tool Works Inc. | Engine-driven welding-type power supplies with portable welding units |
| GB201919021D0 (en) | 2019-12-20 | 2020-02-05 | Reneuron Ltd | Nucleic acid constructs for delivering polynucleotides into exosomes |
| GB202114441D0 (en) | 2021-10-08 | 2021-11-24 | Reneuron Ltd | Proteins and extracellular vesicles |
| KR20250007548A (ko) | 2022-04-15 | 2025-01-14 | 아스펜 뉴로사이언스 인코포레이티드 | 세포의 분화 상태를 분류하는 방법 및 관련 분화된 세포 조성물 |
Family Cites Families (64)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0233838A3 (en) | 1986-02-04 | 1990-01-31 | Incyte Pharmaceuticals, Inc. | Neurite-promoting factor and process for the manufacture thereof |
| US4753635A (en) * | 1986-05-23 | 1988-06-28 | Jacqueline Sagen | Inducing analgesia by implantation of cells releasing neuroactive substances |
| NZ226750A (en) * | 1987-10-29 | 1990-09-26 | Amrad Corp Ltd | Immortalisation of neural precursor cells by introducing a retrovirus vector containing a myc-oncogene |
| US5182111A (en) * | 1987-11-17 | 1993-01-26 | Boston University Research Foundation | In vivo delivery of active factors by co-cultured cell implants |
| DE68928914T2 (de) * | 1988-08-04 | 1999-09-09 | Amrad Corp. Ltd. | (in vitro)-vermehrung von embryonalen stammzellen unter verwendung von leukämie-inhibitionsfaktor (lif) |
| US5082670A (en) * | 1988-12-15 | 1992-01-21 | The Regents Of The University Of California | Method of grafting genetically modified cells to treat defects, disease or damage or the central nervous system |
| US4980174A (en) * | 1988-12-23 | 1990-12-25 | Jacqueline Sagen | Method for alleviating depression |
| WO1991002003A1 (en) | 1989-08-04 | 1991-02-21 | Board Of Regents, The University Of Texas System | Methods and compositions; purified preparation of neural progenitor regulatory factor |
| US5411883A (en) * | 1989-12-26 | 1995-05-02 | Somatix Therapy Corporation | Proliferated neuron progenitor cell product and process |
| WO1991009936A1 (en) | 1989-12-26 | 1991-07-11 | Hana Biologics, Inc. | Proliferated neuron progenitor cell product and process |
| GB9003791D0 (en) * | 1990-02-20 | 1990-04-18 | Ludwig Inst Cancer Res | Transgenic animals,cell lines therefrom,and their use |
| US5196315A (en) | 1990-05-01 | 1993-03-23 | The Johns Hopkins University | Human neuronal cell line |
| US5612211A (en) * | 1990-06-08 | 1997-03-18 | New York University | Stimulation, production and culturing of hematopoietic progenitor cells by fibroblast growth factors |
| US6294346B1 (en) * | 1991-07-08 | 2001-09-25 | Neurospheres Holdings, Ltd. | Use of multipotent neural stem cells and their progeny for the screening of drugs and other biological agents |
| US5980885A (en) * | 1991-07-08 | 1999-11-09 | Neurospheres Holdings Ltd. | Growth factor-induced proliferation of neural precursor cells in vivo |
| US5750376A (en) * | 1991-07-08 | 1998-05-12 | Neurospheres Holdings Ltd. | In vitro growth and proliferation of genetically modified multipotent neural stem cells and their progeny |
| US6497872B1 (en) * | 1991-07-08 | 2002-12-24 | Neurospheres Holdings Ltd. | Neural transplantation using proliferated multipotent neural stem cells and their progeny |
| EP0594669B9 (en) | 1991-07-08 | 2008-03-19 | NeuroSpheres Holdings Ltd. | Growth factor-responsive neural progenitor cells which can be proliferated in vitro. |
| US5851832A (en) * | 1991-07-08 | 1998-12-22 | Neurospheres, Ltd. | In vitro growth and proliferation of multipotent neural stem cells and their progeny |
| US5175103A (en) * | 1991-10-21 | 1992-12-29 | Trustees Of University Of Pennsylvania | Preparation of pure cultures of post-mitotic human neurons |
| WO1993009802A2 (en) | 1991-11-22 | 1993-05-27 | Genentech, Inc. | Tgf-beta to improve neural outcome |
| US5672499A (en) * | 1992-07-27 | 1997-09-30 | California Institute Of Technology | Immoralized neural crest stem cells and methods of making |
| US5589376A (en) * | 1992-07-27 | 1996-12-31 | California Institute Of Technology | Mammalian neural crest stem cells |
| WO1994003199A1 (en) | 1992-08-04 | 1994-02-17 | Regeneron Pharmaceuticals, Inc. | Method of enhancing differentiation and survival of neuronal precursor cells |
| US5356807A (en) * | 1992-09-08 | 1994-10-18 | Cornell Research Foundation | Cultured cell line of adult diploid cells from human brain and meningeal tissue |
| US5453357A (en) * | 1992-10-08 | 1995-09-26 | Vanderbilt University | Pluripotential embryonic stem cells and methods of making same |
| US5690926A (en) * | 1992-10-08 | 1997-11-25 | Vanderbilt University | Pluripotential embryonic cells and methods of making same |
| US7153684B1 (en) * | 1992-10-08 | 2006-12-26 | Vanderbilt University | Pluripotential embryonic stem cells and methods of making same |
| ATE262912T1 (de) * | 1993-01-29 | 2004-04-15 | Neurospheres Holdings Ltd | Genetische modifikation von neuralen stammzellen |
| GB9308271D0 (en) | 1993-04-21 | 1993-06-02 | Univ Edinburgh | Method of isolating and/or enriching and/or selectively propagating pluripotential animal cells and animals for use in said method |
| GB9417831D0 (en) | 1994-09-05 | 1994-10-26 | Biotech & Biolog Scien Res | Biological manipulation |
| WO1996015226A1 (en) * | 1994-11-14 | 1996-05-23 | Neurospheres Holdings Ltd. | Regulation of neural stem cell proliferation |
| US5843780A (en) * | 1995-01-20 | 1998-12-01 | Wisconsin Alumni Research Foundation | Primate embryonic stem cells |
| US5753505A (en) * | 1995-07-06 | 1998-05-19 | Emory University | Neuronal progenitor cells and uses thereof |
| US7544511B2 (en) * | 1996-09-25 | 2009-06-09 | Neuralstem Biopharmaceuticals Ltd. | Stable neural stem cell line methods |
| US5753506A (en) * | 1996-05-23 | 1998-05-19 | Cns Stem Cell Technology, Inc. | Isolation propagation and directed differentiation of stem cells from embryonic and adult central nervous system of mammals |
| US6361996B1 (en) * | 1997-05-07 | 2002-03-26 | University Of Utah Research Foundation | Neuroepithelial stem cells and glial-restricted intermediate precursors |
| US6734015B1 (en) * | 1997-07-04 | 2004-05-11 | University Of Utah Research Foundation | Isolation of lineage-restricted neuronal precursors |
| US5968829A (en) * | 1997-09-05 | 1999-10-19 | Cytotherapeutics, Inc. | Human CNS neural stem cells |
| JP3880795B2 (ja) * | 1997-10-23 | 2007-02-14 | ジェロン・コーポレーション | フィーダー細胞を含まない培養物中で、霊長類由来始原幹細胞を増殖させるための方法 |
| DE19756864C5 (de) | 1997-12-19 | 2014-07-10 | Oliver Brüstle | Neurale Vorläuferzellen, Verfahren zu ihrer Herstellung und ihre Verwendung zur Therapie von neuralen Defekten |
| US6812027B2 (en) | 1998-03-25 | 2004-11-02 | Cornell Research Foundation, Inc. | Discovery, localization, harvest, and propagation of an FGF2 and BDNF-responsive population of neural and neuronal progenitor cells in the adult human forebrain |
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| JP2002034580A (ja) | 2000-01-05 | 2002-02-05 | Japan Science & Technology Corp | 多能性神経系前駆細胞を分離し、精製するための方法および多能性神経系前駆細胞 |
| WO2001053503A1 (en) * | 2000-01-18 | 2001-07-26 | Cornell Research Foundation, Inc. | Neural progenitor cells from hippocampal tissue and a method for isolating and purifying them |
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| US6812017B2 (en) * | 2000-10-11 | 2004-11-02 | Centre National De La Recherche Scientique - Cnrs | Mammalian secreted group IIF phospholipase A2 |
| CN1128217C (zh) * | 2000-12-22 | 2003-11-19 | 复旦大学医学院附属华山医院 | 可表达外源性基因的人神经干细胞及其制备方法 |
| US6852532B2 (en) * | 2001-03-21 | 2005-02-08 | University Of Utah Research Foundation | Method of isolating human neuroepithelial precursor cells from human fetal tissue |
| CA2364095C (en) | 2001-07-20 | 2011-07-12 | Neurostasis, Inc | Production of radial glial cells |
| US9969980B2 (en) * | 2001-09-21 | 2018-05-15 | Garnet Biotherapeutics | Cell populations which co-express CD49c and CD90 |
| AU2003220827A1 (en) * | 2002-03-27 | 2003-10-08 | Institute Of Gene And Brain Science | Method of inducing growth of nerve stem cells |
| IL165088A0 (en) | 2002-05-17 | 2005-12-18 | Kirin Brewery | Transgenic ungulates capable of human antibody production |
| EP2360241A1 (en) * | 2002-06-05 | 2011-08-24 | ES Cell International Pte Ltd. | Stem cells |
| US7371922B2 (en) * | 2002-07-31 | 2008-05-13 | The Board Of Trustees Of The University Of Illinois | Nuclear transfer with porcine embryonic stem cells |
| EP1570052B1 (en) * | 2002-12-02 | 2009-01-21 | AnGes MG, Inc. | Method for culturing neural stem cells using hepatocyte growth factor |
| GB2414995B (en) | 2004-06-09 | 2006-11-15 | Univ Edinburgh | Neural stem cells |
| GB0505510D0 (en) * | 2004-06-09 | 2005-04-27 | Univ Edinburgh | Neural stem cells |
| CA2583473A1 (en) * | 2004-10-05 | 2007-04-04 | University Of Georgia Research Foundation, Inc. | Neuronal progenitors from feeder-free human embryonic stem cell culture |
-
2005
- 2005-06-09 GB GB0511770A patent/GB2414995B/en not_active Expired - Lifetime
- 2005-06-09 WO PCT/GB2005/002289 patent/WO2005121318A2/en not_active Ceased
- 2005-06-09 JP JP2007526548A patent/JP2008501356A/ja active Pending
- 2005-06-09 ES ES05752405.0T patent/ES2557772T3/es not_active Expired - Lifetime
- 2005-06-09 AU AU2005252434A patent/AU2005252434B2/en not_active Expired
- 2005-06-09 DK DK05752405.0T patent/DK1758986T3/en active
- 2005-06-09 CN CN201310025957.7A patent/CN103146649B/zh not_active Expired - Lifetime
- 2005-06-09 CA CA2569978A patent/CA2569978C/en not_active Expired - Lifetime
- 2005-06-09 EP EP05752405.0A patent/EP1758986B1/en not_active Expired - Lifetime
- 2005-06-09 NZ NZ551832A patent/NZ551832A/en not_active IP Right Cessation
- 2005-06-09 EP EP15187477.3A patent/EP3000877B1/en not_active Expired - Lifetime
- 2005-06-09 PL PL05752405T patent/PL1758986T3/pl unknown
- 2005-06-09 US US11/148,431 patent/US8785187B2/en active Active
-
2006
- 2006-12-07 IL IL179919A patent/IL179919A/en active IP Right Grant
-
2011
- 2011-11-11 JP JP2011247986A patent/JP2012034706A/ja active Pending
-
2014
- 2014-07-21 US US14/336,513 patent/US9309495B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005121318A3 (en) | 2006-03-23 |
| GB2414995A (en) | 2005-12-14 |
| US9309495B2 (en) | 2016-04-12 |
| GB0511770D0 (en) | 2005-07-20 |
| US20140370596A1 (en) | 2014-12-18 |
| WO2005121318A2 (en) | 2005-12-22 |
| EP3000877A1 (en) | 2016-03-30 |
| CN103146649B (zh) | 2018-05-22 |
| IL179919A (en) | 2011-09-27 |
| DK1758986T3 (en) | 2016-01-18 |
| EP3000877B1 (en) | 2019-08-14 |
| EP1758986A2 (en) | 2007-03-07 |
| WO2005121318A8 (en) | 2014-08-28 |
| EP1758986B1 (en) | 2015-09-30 |
| AU2005252434A1 (en) | 2005-12-22 |
| US20060014281A1 (en) | 2006-01-19 |
| CN103146649A (zh) | 2013-06-12 |
| GB2414995B (en) | 2006-11-15 |
| JP2012034706A (ja) | 2012-02-23 |
| IL179919A0 (en) | 2007-05-15 |
| JP2008501356A (ja) | 2008-01-24 |
| CA2569978C (en) | 2017-06-06 |
| US8785187B2 (en) | 2014-07-22 |
| CA2569978A1 (en) | 2005-12-22 |
| ES2557772T3 (es) | 2016-01-28 |
| NZ551832A (en) | 2010-01-29 |
| AU2005252434B2 (en) | 2011-11-24 |
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