PL1763356T3 - Kompozycja zawierająca antysensowny oligonukleotyd surwiwiny i gemcytabinę do leczenia raka - Google Patents

Kompozycja zawierająca antysensowny oligonukleotyd surwiwiny i gemcytabinę do leczenia raka

Info

Publication number
PL1763356T3
PL1763356T3 PL05738307T PL05738307T PL1763356T3 PL 1763356 T3 PL1763356 T3 PL 1763356T3 PL 05738307 T PL05738307 T PL 05738307T PL 05738307 T PL05738307 T PL 05738307T PL 1763356 T3 PL1763356 T3 PL 1763356T3
Authority
PL
Poland
Prior art keywords
cancer
antisense oligonucleotide
gemcitabine
treatment
composition
Prior art date
Application number
PL05738307T
Other languages
English (en)
Inventor
Bharvin Kumar Patel
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of PL1763356T3 publication Critical patent/PL1763356T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL05738307T 2004-04-22 2005-04-15 Kompozycja zawierająca antysensowny oligonukleotyd surwiwiny i gemcytabinę do leczenia raka PL1763356T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US56454004P 2004-04-22 2004-04-22
PCT/US2005/012968 WO2005107771A2 (en) 2004-04-22 2005-04-15 Composition comprising a survivin oligonucleotide and gemcitabine for the treatment of cancer
EP05738307A EP1763356B1 (en) 2004-04-22 2005-04-15 Composition comprising a survivin antisense oligonucleotide and gemcitabine for the treatment of cancer

Publications (1)

Publication Number Publication Date
PL1763356T3 true PL1763356T3 (pl) 2008-12-31

Family

ID=35094133

Family Applications (2)

Application Number Title Priority Date Filing Date
PL07119706T PL1913947T3 (pl) 2004-04-22 2005-04-15 Terapia skojarzona do leczenia raka
PL05738307T PL1763356T3 (pl) 2004-04-22 2005-04-15 Kompozycja zawierająca antysensowny oligonukleotyd surwiwiny i gemcytabinę do leczenia raka

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL07119706T PL1913947T3 (pl) 2004-04-22 2005-04-15 Terapia skojarzona do leczenia raka

Country Status (17)

Country Link
US (3) US20070244065A1 (pl)
EP (3) EP2145626A1 (pl)
JP (1) JP2007533742A (pl)
CN (2) CN101683355A (pl)
AT (2) ATE538800T1 (pl)
AU (1) AU2005240020B2 (pl)
BR (1) BRPI0509927A (pl)
CA (1) CA2562750A1 (pl)
CY (2) CY1110440T1 (pl)
DE (1) DE602005008241D1 (pl)
DK (2) DK1913947T3 (pl)
ES (2) ES2376484T3 (pl)
MX (1) MXPA06012132A (pl)
PL (2) PL1913947T3 (pl)
PT (2) PT1763356E (pl)
SI (2) SI1913947T1 (pl)
WO (1) WO2005107771A2 (pl)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2310006A4 (en) 2008-07-03 2012-04-25 Mayo Foundation CANCER TREATMENT
FR2955112B1 (fr) 2010-01-14 2012-01-20 Isp Investments Inc Nouveaux peptides anti-age modulateurs de la survivine et compositions les comprenant
WO2012058462A2 (en) * 2010-10-29 2012-05-03 Isis Pharmaceuticals, Inc. Combination therapy for the treatment of cancer
EP2707030B1 (en) 2011-05-09 2020-02-19 Mayo Foundation For Medical Education And Research Cancer treatments
EP3967306A1 (en) 2012-10-01 2022-03-16 Mayo Foundation for Medical Education and Research Cancer treatments
US20160250351A1 (en) 2014-06-13 2016-09-01 Mayo Foundation For Medical Education And Research Treating Lymphomas
KR20210125603A (ko) 2014-06-16 2021-10-18 메이오 파운데이션 포 메디칼 에쥬케이션 앤드 리써치 골수종의 치료
US9446148B2 (en) 2014-10-06 2016-09-20 Mayo Foundation For Medical Education And Research Carrier-antibody compositions and methods of making and using the same
TW201707725A (zh) 2015-08-18 2017-03-01 美國馬友醫藥教育研究基金會 載體-抗體組合物及其製造及使用方法
TW201713360A (en) 2015-10-06 2017-04-16 Mayo Foundation Methods of treating cancer using compositions of antibodies and carrier proteins
US11571469B2 (en) 2016-01-07 2023-02-07 Mayo Foundation For Medical Education And Research Methods of treating cancer with interferon wherein the cancer cells are HLA negative or have reduced HLA expression
EP3413874A4 (en) 2016-02-12 2020-01-22 Mayo Foundation for Medical Education and Research TREATMENTS FOR BLOOD CANCER
AU2017238119A1 (en) 2016-03-21 2018-10-11 Mayo Foundation For Medical Education And Research Methods for reducing toxicity of a chemotherapeutic drug
WO2017165439A1 (en) 2016-03-21 2017-09-28 Mayo Foundation For Medical Education And Research Methods for improving the therapeutic index for a chemotherapeutic drug
US10618969B2 (en) 2016-04-06 2020-04-14 Mayo Foundation For Medical Education And Research Carrier-binding agent compositions and methods of making and using the same
WO2018045238A1 (en) 2016-09-01 2018-03-08 Mayo Foundation For Medical Education And Research Methods and compositions for targeting t-cell cancers
ES2937291T3 (es) 2016-09-01 2023-03-27 Mayo Found Medical Education & Res Composiciones de agentes que se unen al transportador PD-L1 y métodos de uso de las mismas para tratar cánceres
CN109890422A (zh) 2016-09-06 2019-06-14 梅约医学教育与研究基金会 紫杉醇-白蛋白-结合剂组合物及使用和制备该组合物的方法
US11590098B2 (en) 2016-09-06 2023-02-28 Mayo Foundation For Medical Education And Research Methods of treating triple-negative breast cancer using compositions of antibodies and carrier proteins
CN109843924A (zh) 2016-09-06 2019-06-04 梅约医学教育与研究基金会 治疗表达pd-l1的癌症的方法
IL291917A (en) * 2019-10-02 2022-06-01 Sirnaomics Inc Oligonucleotides with nucleoside analogs, compositions comprising same and uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0184365B1 (en) * 1984-12-04 1993-08-04 Eli Lilly And Company Improvements in the treatment of tumors in mammals
US6077709A (en) * 1998-09-29 2000-06-20 Isis Pharmaceuticals Inc. Antisense modulation of Survivin expression
US6335194B1 (en) * 1998-09-29 2002-01-01 Isis Pharmaceuticals, Inc. Antisense modulation of survivin expression
US6838283B2 (en) * 1998-09-29 2005-01-04 Isis Pharmaceuticals Inc. Antisense modulation of survivin expression
MXPA05008319A (es) * 2003-02-10 2006-02-28 Santaris Pharma As Compuestos oligomericos para la modulacion de la expresion de survivina.

Also Published As

Publication number Publication date
ES2308488T3 (es) 2008-12-01
US20090247611A1 (en) 2009-10-01
EP1763356B1 (en) 2008-07-16
EP1913947A1 (en) 2008-04-23
CN1950094A (zh) 2007-04-18
AU2005240020A1 (en) 2005-11-17
SI1913947T1 (sl) 2012-02-29
BRPI0509927A (pt) 2007-09-25
DK1763356T3 (da) 2008-10-13
DK1913947T3 (da) 2012-02-06
SI1763356T1 (sl) 2008-12-31
EP2145626A1 (en) 2010-01-20
DE602005008241D1 (de) 2008-08-28
ATE538800T1 (de) 2012-01-15
WO2005107771A2 (en) 2005-11-17
CA2562750A1 (en) 2005-11-17
US20070244065A1 (en) 2007-10-18
ES2376484T3 (es) 2012-03-14
JP2007533742A (ja) 2007-11-22
CY1110440T1 (el) 2015-04-29
PL1913947T3 (pl) 2012-05-31
EP1913947B1 (en) 2011-12-28
EP1763356A2 (en) 2007-03-21
CN101683355A (zh) 2010-03-31
PT1913947E (pt) 2012-01-19
US20120022140A1 (en) 2012-01-26
PT1763356E (pt) 2008-09-05
WO2005107771A3 (en) 2006-06-08
AU2005240020B2 (en) 2011-02-10
ATE401088T1 (de) 2008-08-15
CY1112397T1 (el) 2015-12-09
MXPA06012132A (es) 2007-01-17

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