PL1778272T3 - Zastosowanie kombinacji cyklosporyny i pegylowanych interferonów do leczenia zapalenia wątroby typu C (HCV) - Google Patents

Zastosowanie kombinacji cyklosporyny i pegylowanych interferonów do leczenia zapalenia wątroby typu C (HCV)

Info

Publication number: PL1778272T3
Authority: PL; Poland
Prior art keywords: cyclosporin; hcv; combination; treating hepatitis; pegylated interferons
Prior art date: 2004-07-14

Application number

PL05759733T

Other languages

English (en)

Inventor

Catherine Cornu-Artis

Guylaine Vachon

Yoko Uryuhara

Kazuo Asakawa

Reinhild Elisabeth Mertes

Shinsyou Yoshiba

Original Assignee

Novartis Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-07-14

Filing date

2005-07-13

Publication date

2011-07-29

2005-07-13 Application filed by Novartis Ag filed Critical Novartis Ag

2011-07-29 Publication of PL1778272T3 publication Critical patent/PL1778272T3/pl

Links

PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 title abstract 3
229930105110 Cyclosporin A Natural products 0.000 title abstract 2
108010036949 Cyclosporine Proteins 0.000 title abstract 2
102000014150 Interferons Human genes 0.000 title abstract 2
108010050904 Interferons Proteins 0.000 title abstract 2
229960001265 ciclosporin Drugs 0.000 title abstract 2
229930182912 cyclosporin Natural products 0.000 title 1
208000006454 hepatitis Diseases 0.000 title 1
231100000283 hepatitis Toxicity 0.000 title 1
229940047124 interferons Drugs 0.000 title 1
208000015181 infectious disease Diseases 0.000 abstract 1
229940079322 interferon Drugs 0.000 abstract 1
208000024891 symptom Diseases 0.000 abstract 1
229920003169 water-soluble polymer Polymers 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A61K38/212—IFN-alpha
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Gastroenterology & Hepatology (AREA)
Immunology (AREA)
Epidemiology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Zoology (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Virology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Molecular Biology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Peptides Or Proteins (AREA)

PL05759733T 2004-07-14 2005-07-13 Zastosowanie kombinacji cyklosporyny i pegylowanych interferonów do leczenia zapalenia wątroby typu C (HCV) PL1778272T3 (pl)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
EP04016583		2004-07-14
PCT/EP2005/007633 WO2006005610A1 (en)	2004-07-14	2005-07-13	Use of a combination of cyclosporine and pegylated interferon for treating hepatitis c (hcv)
EP05759733A EP1778272B1 (en)	2004-07-14	2005-07-13	Use of a combination of cyclosporin and pegylated interferons for treating hepatitis c (hcv)

Publications (1)

Publication Number	Publication Date
PL1778272T3 true PL1778272T3 (pl)	2011-07-29

Family

ID=34972493

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL05759733T PL1778272T3 (pl)	2004-07-14	2005-07-13	Zastosowanie kombinacji cyklosporyny i pegylowanych interferonów do leczenia zapalenia wątroby typu C (HCV)

Country Status (15)

Country	Link
US (1)	US7671017B2 (pl)
EP (1)	EP1778272B1 (pl)
JP (1)	JP2008506648A (pl)
KR (1)	KR20070036175A (pl)
CN (1)	CN1984671A (pl)
AT (1)	ATE497775T1 (pl)
AU (1)	AU2005261868B2 (pl)
BR (1)	BRPI0513370A (pl)
CA (1)	CA2573207C (pl)
DE (1)	DE602005026294D1 (pl)
ES (1)	ES2359925T3 (pl)
MX (1)	MX2007000503A (pl)
PL (1)	PL1778272T3 (pl)
RU (1)	RU2394589C2 (pl)
WO (1)	WO2006005610A1 (pl)

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US7196161B2 (en)	2004-10-01	2007-03-27	Scynexis Inc.	3-ether and 3-thioether substituted cyclosporin derivatives for the treatment and prevention of hepatitis C infection
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EP1931696B1 (en)	2005-09-30	2011-02-16	Scynexis, Inc.	Arylalkyl and heteroarylalkyl derivatives of cyclosporine a for the treatment and prevention of viral infection
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EP2023918B1 (en)	2006-05-19	2011-03-23	Scynexis, Inc.	Cyclosporins for the treatment and prevention of ocular disorders
WO2008069917A2 (en)	2006-11-20	2008-06-12	Scynexis, Inc.	Novel cyclic peptides
CN102083852A (zh)	2008-06-06	2011-06-01	西尼克斯公司	环孢菌素类似物及其在治疗hcv感染中的应用
CA2737376A1 (en) *	2008-09-17	2010-03-25	Boehringer Ingelheim International Gmbh	Combination of hcv ns3 protease inhibitor with interferon and ribavirin
CN102257159A (zh) *	2008-12-18	2011-11-23	弗·哈夫曼-拉罗切有限公司	用于hcv治疗应答的生物标志物
EP2376524B1 (en)	2008-12-31	2017-03-15	Cypralis Limited	Derivatives of cyclosporin a
KR20110111321A (ko)	2009-01-30	2011-10-10	이난타 파마슈티칼스, 인코포레이티드	Ｃ형 간염을 예방하거나 치료하기 위한 사이클로스포린 유사체
US8481483B2 (en)	2009-02-19	2013-07-09	Enanta Pharmaceuticals, Inc.	Cyclosporin analogues
AR075584A1 (es) *	2009-02-27	2011-04-20	Intermune Inc	COMPOSICIONES TERAPEUTICAS QUE COMPRENDEN beta-D-2'-DESOXI-2'-FLUORO-2'-C-METILCITIDINA Y UN DERIVADO DE ACIDO ISOINDOL CARBOXILICO Y SUS USOS. COMPUESTO.
US8349312B2 (en)	2009-07-09	2013-01-08	Enanta Pharmaceuticals, Inc.	Proline substituted cyclosporin analogues
US8367053B2 (en)	2009-07-09	2013-02-05	Enanta Pharmaceuticals, Inc.	Cyclosporin analogues
US8685917B2 (en)	2009-07-09	2014-04-01	Enanta Pharmaceuticals, Inc.	Cyclosporin analogues
EA201200650A1 (ru)	2009-10-30	2012-12-28	Бёрингер Ингельхайм Интернациональ Гмбх	Курсы комбинированного лечения вируса гепатита с, включающие bi201335, интерферон-альфа и рибавирин
US8623814B2 (en)	2010-02-23	2014-01-07	Enanta Pharmaceuticals, Inc.	Antiviral agents
JP2013529627A (ja)	2010-06-24	2013-07-22	パンメドリミテッド	ヒドロキシクロロキンまたはヒドロキシクロロキンおよび抗ウイルス剤の組合せを使用するｃ型肝炎ウイルス関連疾患の処置
WO2012176149A1 (en)	2011-06-23	2012-12-27	Panmed Ltd.	Treatment of hepatitis c virus
US8466159B2 (en)	2011-10-21	2013-06-18	Abbvie Inc.	Methods for treating HCV
DE202012012955U1 (de)	2011-10-21	2014-07-14	Abbvie Inc.	Eine Kombination aus mindestens zwei direkt wirkenden antiviralen Wirkstoffen (DAAs) für die Verwendung zur Behandlung von HCV
EP2583677A3 (en)	2011-10-21	2013-07-03	Abbvie Inc.	Methods for treating HCV comprising at least two direct acting antiviral agent, ribavirin but not interferon.
US8492386B2 (en)	2011-10-21	2013-07-23	Abbvie Inc.	Methods for treating HCV
WO2014085623A1 (en)	2012-11-28	2014-06-05	Enanta Pharmaceuticals, Inc.	Novel [n-me-4-hydroxyleucine]-9-cyclosporin analogues
WO2014122537A2 (en)	2013-02-05	2014-08-14	Genoscience Sa	Pharmaceutical compositions and methods of treating hepatitis c virus infection using a combination of hydroxychloroquine and ribavirin
JP2016538317A (ja)	2013-08-26	2016-12-08	エナンタファーマシューティカルズインコーポレイテッド	Ｃ型肝炎を防止または治療するための新規シクロスポリン類似体
US9669095B2 (en)	2014-11-03	2017-06-06	Enanta Pharmaceuticals, Inc.	Cyclosporin analogues for preventing or treating hepatitis C infection
EA201892448A1 (ru)	2016-04-28	2019-06-28	Эмори Юниверсити	Алкинсодержащие нуклеотидные и нуклеозидные терапевтические композиции и связанные с ними способы применения

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2005
- 2005-07-13 US US11/572,110 patent/US7671017B2/en not_active Expired - Fee Related
- 2005-07-13 DE DE602005026294T patent/DE602005026294D1/de not_active Expired - Lifetime
- 2005-07-13 MX MX2007000503A patent/MX2007000503A/es active IP Right Grant
- 2005-07-13 CN CNA2005800237603A patent/CN1984671A/zh active Pending
- 2005-07-13 EP EP05759733A patent/EP1778272B1/en not_active Expired - Lifetime
- 2005-07-13 RU RU2007105354/14A patent/RU2394589C2/ru not_active IP Right Cessation
- 2005-07-13 CA CA2573207A patent/CA2573207C/en not_active Expired - Fee Related
- 2005-07-13 BR BRPI0513370-0A patent/BRPI0513370A/pt not_active IP Right Cessation
- 2005-07-13 JP JP2007520752A patent/JP2008506648A/ja active Pending
- 2005-07-13 AU AU2005261868A patent/AU2005261868B2/en not_active Ceased
- 2005-07-13 WO PCT/EP2005/007633 patent/WO2006005610A1/en not_active Ceased
- 2005-07-13 PL PL05759733T patent/PL1778272T3/pl unknown
- 2005-07-13 KR KR1020077003409A patent/KR20070036175A/ko not_active Ceased
- 2005-07-13 AT AT05759733T patent/ATE497775T1/de active
- 2005-07-13 ES ES05759733T patent/ES2359925T3/es not_active Expired - Lifetime

Also Published As

Publication number	Publication date
WO2006005610A1 (en)	2006-01-19
EP1778272A1 (en)	2007-05-02
AU2005261868A1 (en)	2006-01-19
AU2005261868B2 (en)	2009-01-15
US7671017B2 (en)	2010-03-02
BRPI0513370A (pt)	2008-05-06
ATE497775T1 (de)	2011-02-15
MX2007000503A (es)	2007-03-08
US20080138316A1 (en)	2008-06-12
EP1778272B1 (en)	2011-02-09
CA2573207A1 (en)	2006-01-19
JP2008506648A (ja)	2008-03-06
RU2394589C2 (ru)	2010-07-20
CA2573207C (en)	2013-04-16
KR20070036175A (ko)	2007-04-02
CN1984671A (zh)	2007-06-20
ES2359925T3 (es)	2011-05-30
RU2007105354A (ru)	2008-09-10
DE602005026294D1 (de)	2011-03-24

Publication	Publication Date	Title
PL1778272T3 (pl)	2011-07-29	Zastosowanie kombinacji cyklosporyny i pegylowanych interferonów do leczenia zapalenia wątroby typu C (HCV)
AR021876A1 (es)	2002-08-07	Terapia de combinacion para vhc por induccion de ribavirina - interferon alfa pegilado
MY141594A (en)	2010-05-14	3'-PRODRUGS OF 2'-DEOXY-ß-L-NUCLEOSIDES
TW200716095A (en)	2007-05-01	Method of treating interferon non-responders using HCV protease inhibitor
NO20073632L (no)	2007-09-17	Behandling av hepatitt C med interferon-beta i en asiatisk populasjon
AR045870A1 (es)	2005-11-16	Terapia de combinacion para la infeccion de virus de hepatitis c
WO2006110655A3 (en)	2007-06-28	Compounds, compositions and methods for the treatment of poxvirus infections
IL158558A0 (en)	2004-05-12	Antiviral compounds
MXPA05005203A (es)	2006-01-27	Vacuna contra vhc.
RU2010153688A (ru)	2012-07-20	Режим дозирования телапревира
NZ588655A (en)	2012-12-21	Treatment of hepatitis c virus infections with telaprevir (vx-950) in patients non-responsive to treatment with pegylated interfer0n-alpha-2a/2b and ribavirin
PE20001386A1 (es)	2000-12-14	Terapia de combinacion para el vhc por induccion de ribavirina-interferon alfa
AR039915A1 (es)	2005-03-09	Tratamiento de la hepatitis c en la poblacion asiatica
WO2008073864A8 (en)	2008-09-04	Novel combinations
UA95299C2 (ru)	2011-07-25	Профилактический или терапевтический агент против вирусного заболевания, вызванного вирусом гепатита с
TW200740455A (en)	2007-11-01	PEG-IFN alpha and ribavirin for HBV treatment
DK1311279T3 (da)	2007-02-12	Behandling af hepatitis C med thymosin, interferon og ribavirin
WO2004006843A3 (en)	2004-07-22	Combination therapies with l-fmau for the treatment of hepatitis b virus infection
WO2004067024A3 (en)	2004-09-16	Hcv combination therapy
DK1311286T3 (da)	2006-10-30	Behandling af hepatitis C med thymosin og pegyleret interferon
TH100996B (th)	2010-04-23	การรักษาโรคตับอักเสบซีในประชากรชาวเอเชีย
TH87484A (th)	2007-11-09	Peg-ifn อัลฟา และริบาวิรินสำหรับรักษา hbv
TH100996A (th)	2010-04-23	การรักษาโรคตับอักเสบซีในประชากรชาวเอเชีย
HK1072721A1 (zh)	2005-09-09	聚(烷撑)聚合化合物及其用途