PL1778660T3 - Sposób rozdzielania paklitakselu i cefalomanniny - Google Patents
Sposób rozdzielania paklitakselu i cefalomanninyInfo
- Publication number
- PL1778660T3 PL1778660T3 PL05770208T PL05770208T PL1778660T3 PL 1778660 T3 PL1778660 T3 PL 1778660T3 PL 05770208 T PL05770208 T PL 05770208T PL 05770208 T PL05770208 T PL 05770208T PL 1778660 T3 PL1778660 T3 PL 1778660T3
- Authority
- PL
- Poland
- Prior art keywords
- sub
- cephalomannin
- paclitaxel
- separation
- mixture containing
- Prior art date
Links
- 229930012538 Paclitaxel Natural products 0.000 title abstract 2
- 229960001592 paclitaxel Drugs 0.000 title abstract 2
- RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 title abstract 2
- 238000000034 method Methods 0.000 title 1
- 238000000926 separation method Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 2
- 239000002798 polar solvent Substances 0.000 abstract 2
- NTIZESTWPVYFNL-UHFFFAOYSA-N Methyl isobutyl ketone Chemical compound CC(C)CC(C)=O NTIZESTWPVYFNL-UHFFFAOYSA-N 0.000 abstract 1
- UIHCLUNTQKBZGK-UHFFFAOYSA-N Methyl isobutyl ketone Natural products CCC(C)C(C)=O UIHCLUNTQKBZGK-UHFFFAOYSA-N 0.000 abstract 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 abstract 1
- 150000001338 aliphatic hydrocarbons Chemical class 0.000 abstract 1
- 150000004945 aromatic hydrocarbons Chemical class 0.000 abstract 1
- 238000004440 column chromatography Methods 0.000 abstract 1
- 150000001983 dialkylethers Chemical class 0.000 abstract 1
- 239000000741 silica gel Substances 0.000 abstract 1
- 229910002027 silica gel Inorganic materials 0.000 abstract 1
- 239000011877 solvent mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Epoxy Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US58540204P | 2004-07-02 | 2004-07-02 | |
| PCT/US2005/023483 WO2006014345A1 (en) | 2004-07-02 | 2005-07-01 | Process for the separation of paclitaxel and cephalomannin |
| EP05770208A EP1778660B1 (en) | 2004-07-02 | 2005-07-01 | Process for the separation of paclitaxel and cephalomannin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL1778660T3 true PL1778660T3 (pl) | 2009-07-31 |
Family
ID=35057023
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL05770208T PL1778660T3 (pl) | 2004-07-02 | 2005-07-01 | Sposób rozdzielania paklitakselu i cefalomanniny |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20080214847A1 (pl) |
| EP (1) | EP1778660B1 (pl) |
| JP (1) | JP2008505108A (pl) |
| KR (1) | KR20070045219A (pl) |
| AT (1) | ATE421959T1 (pl) |
| DE (1) | DE602005012587D1 (pl) |
| ES (1) | ES2320471T3 (pl) |
| PL (1) | PL1778660T3 (pl) |
| PT (1) | PT1778660E (pl) |
| WO (1) | WO2006014345A1 (pl) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112645906A (zh) * | 2020-12-29 | 2021-04-13 | 重庆臻源红豆杉发展有限公司 | 一种高效层析分离纯化紫杉醇的方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2696462B1 (fr) * | 1992-10-05 | 1994-11-25 | Rhone Poulenc Rorer Sa | Procédé d'obtention de la désacétyl-10 baccatine III. |
| FR2696463B1 (fr) * | 1992-10-05 | 1994-11-25 | Rhone Poulenc Rorer Sa | Procédé d'obtention de la désacétyl-10 baccatine III. |
| WO2002038556A2 (en) * | 2000-11-08 | 2002-05-16 | Actipharm, Inc. | Process for mass production of gmp paclitaxel and related taxanes |
| US6333419B1 (en) * | 2000-11-28 | 2001-12-25 | Indena Spa | Chromatographic separation method of paclitaxel and cephalomannin |
-
2005
- 2005-07-01 DE DE602005012587T patent/DE602005012587D1/de not_active Expired - Lifetime
- 2005-07-01 EP EP05770208A patent/EP1778660B1/en not_active Expired - Lifetime
- 2005-07-01 PT PT05770208T patent/PT1778660E/pt unknown
- 2005-07-01 PL PL05770208T patent/PL1778660T3/pl unknown
- 2005-07-01 KR KR1020077002552A patent/KR20070045219A/ko not_active Withdrawn
- 2005-07-01 JP JP2007519472A patent/JP2008505108A/ja active Pending
- 2005-07-01 ES ES05770208T patent/ES2320471T3/es not_active Expired - Lifetime
- 2005-07-01 AT AT05770208T patent/ATE421959T1/de not_active IP Right Cessation
- 2005-07-01 US US11/631,223 patent/US20080214847A1/en not_active Abandoned
- 2005-07-01 WO PCT/US2005/023483 patent/WO2006014345A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP1778660B1 (en) | 2009-01-28 |
| DE602005012587D1 (de) | 2009-03-19 |
| PT1778660E (pt) | 2009-03-10 |
| KR20070045219A (ko) | 2007-05-02 |
| EP1778660A1 (en) | 2007-05-02 |
| ATE421959T1 (de) | 2009-02-15 |
| WO2006014345A1 (en) | 2006-02-09 |
| JP2008505108A (ja) | 2008-02-21 |
| ES2320471T3 (es) | 2009-05-22 |
| US20080214847A1 (en) | 2008-09-04 |
| WO2006014345A8 (en) | 2006-10-05 |
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