PL1778677T3 - Heterocykliczne skondensowane związki użyteczne jako środki antydiuretyczne - Google Patents
Heterocykliczne skondensowane związki użyteczne jako środki antydiuretyczneInfo
- Publication number
- PL1778677T3 PL1778677T3 PL05781746T PL05781746T PL1778677T3 PL 1778677 T3 PL1778677 T3 PL 1778677T3 PL 05781746 T PL05781746 T PL 05781746T PL 05781746 T PL05781746 T PL 05781746T PL 1778677 T3 PL1778677 T3 PL 1778677T3
- Authority
- PL
- Poland
- Prior art keywords
- compounds useful
- antidiuretic agents
- heterocyclic condensed
- condensed compounds
- antidiuretic
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 4
- 229940124538 antidiuretic agent Drugs 0.000 title abstract 2
- 239000003160 antidiuretic agent Substances 0.000 title abstract 2
- 125000000623 heterocyclic group Chemical group 0.000 title 1
- 102000004136 Vasopressin Receptors Human genes 0.000 abstract 1
- 108090000643 Vasopressin Receptors Proteins 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000018 receptor agonist Substances 0.000 abstract 1
- 229940044601 receptor agonist Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US60289004P | 2004-08-20 | 2004-08-20 | |
| EP04104006A EP1627876A1 (en) | 2004-08-20 | 2004-08-20 | Heterocyclic condensed compounds useful as antidiuretic agents |
| PCT/EP2005/054081 WO2006018443A1 (en) | 2004-08-20 | 2005-08-18 | Heterocyclic condensed compounds useful as antidiuretic agents |
| EP05781746A EP1778677B1 (en) | 2004-08-20 | 2005-08-18 | Heterocyclic condensed compounds useful as antidiuretic agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL1778677T3 true PL1778677T3 (pl) | 2010-07-30 |
Family
ID=34929464
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL05781746T PL1778677T3 (pl) | 2004-08-20 | 2005-08-18 | Heterocykliczne skondensowane związki użyteczne jako środki antydiuretyczne |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US8063038B2 (pl) |
| EP (2) | EP1627876A1 (pl) |
| JP (1) | JP4705105B2 (pl) |
| KR (1) | KR100877336B1 (pl) |
| CN (1) | CN1968947A (pl) |
| AT (1) | ATE457026T1 (pl) |
| AU (1) | AU2005273875B2 (pl) |
| CA (1) | CA2567782A1 (pl) |
| CY (1) | CY1110619T1 (pl) |
| DE (1) | DE602005019241D1 (pl) |
| DK (1) | DK1778677T3 (pl) |
| ES (1) | ES2339786T3 (pl) |
| HR (1) | HRP20100250T1 (pl) |
| IL (1) | IL178839A0 (pl) |
| MX (1) | MX2007001861A (pl) |
| NO (1) | NO20071476L (pl) |
| PL (1) | PL1778677T3 (pl) |
| PT (1) | PT1778677E (pl) |
| RU (1) | RU2359969C2 (pl) |
| SI (1) | SI1778677T1 (pl) |
| WO (1) | WO2006018443A1 (pl) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0000079D0 (en) * | 2000-01-05 | 2000-02-23 | Ferring Bv | Novel antidiuretic agents |
| EP1632494A1 (en) | 2004-08-24 | 2006-03-08 | Ferring B.V. | Vasopressin v1a antagonists |
| BRPI0811204A8 (pt) | 2007-05-10 | 2015-09-22 | Bristol Myers Squibb Co | Tetra-hidroibenzo-1,4-diazepinas substituídas por arila e heteroarila e uso das mesmas para bloquear a recaptação de norepinefrina, dopamina e serotonina |
| US9447049B2 (en) | 2010-03-01 | 2016-09-20 | University Of Tennessee Research Foundation | Compounds for treatment of cancer |
| UA105005C2 (uk) | 2008-06-16 | 2014-04-10 | Юніверсіті Оф Теннессі Рісерч Фаундейшн | Сполуки для лікування раку |
| US9029408B2 (en) | 2008-06-16 | 2015-05-12 | Gtx, Inc. | Compounds for treatment of cancer |
| JP5368556B2 (ja) * | 2008-07-16 | 2013-12-18 | エフ．ホフマン−ラ ロシュ アーゲー | 心臓血管疾患の処置のための新規ヘテロシクリル化合物 |
| WO2011005842A1 (en) | 2009-07-09 | 2011-01-13 | Gilead Sciences, Inc. | Anti-rsv compounds |
| JP2011057661A (ja) * | 2009-08-14 | 2011-03-24 | Bayer Cropscience Ag | 殺虫性カルボキサミド類 |
| CA2791738C (en) | 2010-03-01 | 2020-06-09 | Gtx, Inc. | Aryl imidazolyl compounds for the treatment of cancer |
| US9119878B2 (en) | 2010-07-08 | 2015-09-01 | Wellesley Pharmaceuticals, Llc | Extended-release formulation for reducing the frequency of urination and method of use thereof |
| MY173582A (en) * | 2012-01-04 | 2020-02-04 | Wellesley Pharmaceuticals Llc | Extended-release formulation for reducing the frequency of urination and method of use thereof |
| RU2597156C2 (ru) * | 2012-01-04 | 2016-09-10 | УЭЛЛСЛИ ФАРМАСЬЮТИКАЛЗ, ЭлЭлСи | Состав с отсроченным высвобождением для уменьшения частоты мочеиспускания и способ его применения |
| EP2612663A1 (en) * | 2012-01-04 | 2013-07-10 | Wellesley Pharmaceuticals, LLC | Extended-release formulation for reducing the frequency of urination and method of use thereof |
| EP2612662B1 (en) * | 2012-01-04 | 2020-03-04 | Wellesley Pharmaceuticals, LLC | Delayed-release formulation for reducing the frequency of urination and method of use thereof |
| NZ712594A (en) * | 2012-03-19 | 2016-09-30 | Wellesley Pharmaceuticals Llc | Extended-release formulation for reducing the frequency of urination and method of use thereof |
| US10596127B2 (en) | 2013-03-14 | 2020-03-24 | Wellesley Pharmaceuticals, Llc | Composition for reducing the frequency of urination, method of making and use thereof |
| WO2014208296A1 (ja) * | 2013-06-25 | 2014-12-31 | イハラケミカル工業株式会社 | ニトロベンゼン化合物を製造する方法 |
| CN106810508B (zh) * | 2017-01-05 | 2019-12-10 | 浙江农林大学暨阳学院 | 一种铁催化多组分反应合成苯并[1,4]-氧氮杂卓化合物的方法 |
| WO2019003433A1 (ja) * | 2017-06-30 | 2019-01-03 | 大塚製薬株式会社 | ベンゾアゼピン誘導体 |
| CN114853728B (zh) * | 2022-05-07 | 2023-11-07 | 四川制药制剂有限公司 | 一种富马酸伏诺拉生片及其制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL104853A (en) * | 1992-02-27 | 1997-11-20 | Yamanouchi Pharma Co Ltd | Benzodiazepine derivatives, their preparation and pharmaceutical compositions containing them |
| US5512563A (en) * | 1993-07-29 | 1996-04-30 | American Cyanamid Company | Tricyclic benzazepine vasopressin antagonists |
| ES2229523T3 (es) * | 1997-07-30 | 2005-04-16 | Wyeth | Agonistas triciclicos de la vasopresina. |
| IL133788A0 (en) * | 1997-07-30 | 2001-04-30 | American Home Prod | Tricyclic vasopressin agonists |
| GB0015601D0 (en) * | 2000-06-26 | 2000-08-16 | Ferring Bv | Novel antidiuretic agents |
-
2004
- 2004-08-20 EP EP04104006A patent/EP1627876A1/en not_active Withdrawn
-
2005
- 2005-08-18 US US11/660,207 patent/US8063038B2/en not_active Expired - Fee Related
- 2005-08-18 PL PL05781746T patent/PL1778677T3/pl unknown
- 2005-08-18 CN CNA2005800192975A patent/CN1968947A/zh active Pending
- 2005-08-18 HR HR20100250T patent/HRP20100250T1/hr unknown
- 2005-08-18 RU RU2007101237/04A patent/RU2359969C2/ru not_active IP Right Cessation
- 2005-08-18 DE DE602005019241T patent/DE602005019241D1/de not_active Expired - Lifetime
- 2005-08-18 AU AU2005273875A patent/AU2005273875B2/en not_active Ceased
- 2005-08-18 MX MX2007001861A patent/MX2007001861A/es active IP Right Grant
- 2005-08-18 WO PCT/EP2005/054081 patent/WO2006018443A1/en not_active Ceased
- 2005-08-18 PT PT05781746T patent/PT1778677E/pt unknown
- 2005-08-18 SI SI200530930T patent/SI1778677T1/sl unknown
- 2005-08-18 CA CA002567782A patent/CA2567782A1/en not_active Abandoned
- 2005-08-18 ES ES05781746T patent/ES2339786T3/es not_active Expired - Lifetime
- 2005-08-18 AT AT05781746T patent/ATE457026T1/de active
- 2005-08-18 EP EP05781746A patent/EP1778677B1/en not_active Expired - Lifetime
- 2005-08-18 KR KR1020077002387A patent/KR100877336B1/ko not_active Expired - Fee Related
- 2005-08-18 DK DK05781746.2T patent/DK1778677T3/da active
- 2005-08-18 JP JP2007526462A patent/JP4705105B2/ja not_active Expired - Fee Related
-
2006
- 2006-10-24 IL IL178839A patent/IL178839A0/en unknown
-
2007
- 2007-03-19 NO NO20071476A patent/NO20071476L/no not_active Application Discontinuation
-
2010
- 2010-04-26 CY CY20101100370T patent/CY1110619T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2005273875B2 (en) | 2009-08-27 |
| ATE457026T1 (de) | 2010-02-15 |
| RU2359969C2 (ru) | 2009-06-27 |
| CY1110619T1 (el) | 2015-04-29 |
| JP2008509972A (ja) | 2008-04-03 |
| AU2005273875A1 (en) | 2006-02-23 |
| MX2007001861A (es) | 2007-04-24 |
| SI1778677T1 (sl) | 2010-09-30 |
| NO20071476L (no) | 2007-03-19 |
| HK1100290A1 (en) | 2007-09-14 |
| JP4705105B2 (ja) | 2011-06-22 |
| US20080234250A1 (en) | 2008-09-25 |
| US8063038B2 (en) | 2011-11-22 |
| KR100877336B1 (ko) | 2009-01-07 |
| EP1778677A1 (en) | 2007-05-02 |
| EP1778677B1 (en) | 2010-02-03 |
| CN1968947A (zh) | 2007-05-23 |
| IL178839A0 (en) | 2007-03-08 |
| HRP20100250T1 (hr) | 2010-06-30 |
| ES2339786T3 (es) | 2010-05-25 |
| DE602005019241D1 (de) | 2010-03-25 |
| EP1627876A1 (en) | 2006-02-22 |
| KR20070027761A (ko) | 2007-03-09 |
| RU2007101237A (ru) | 2008-09-27 |
| PT1778677E (pt) | 2010-03-17 |
| DK1778677T3 (da) | 2010-04-19 |
| CA2567782A1 (en) | 2006-02-23 |
| WO2006018443A1 (en) | 2006-02-23 |
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