PL1786759T3 - Nowe pochodne 3,5-seko-4-norcholestanowe i ich zastosowanie - Google Patents

Nowe pochodne 3,5-seko-4-norcholestanowe i ich zastosowanie

Info

Publication number
PL1786759T3
PL1786759T3 PL05798253T PL05798253T PL1786759T3 PL 1786759 T3 PL1786759 T3 PL 1786759T3 PL 05798253 T PL05798253 T PL 05798253T PL 05798253 T PL05798253 T PL 05798253T PL 1786759 T3 PL1786759 T3 PL 1786759T3
Authority
PL
Poland
Prior art keywords
norcholestane
seco
novel derivatives
derivatives
novel
Prior art date
Application number
PL05798253T
Other languages
English (en)
Inventor
Thierry Bordet
Cyrille Drouot
Original Assignee
Trophos
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Trophos filed Critical Trophos
Publication of PL1786759T3 publication Critical patent/PL1786759T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/32—Oximes
    • C07C251/34—Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C07C251/44—Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with the carbon atom of at least one of the oxyimino groups being part of a ring other than a six-membered aromatic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/15—Oximes (>C=N—O—); Hydrazines (>N—N<); Hydrazones (>N—N=) ; Imines (C—N=C)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/385—Saturated compounds containing a keto group being part of a ring
    • C07C49/487—Saturated compounds containing a keto group being part of a ring containing hydroxy groups
    • C07C49/507—Saturated compounds containing a keto group being part of a ring containing hydroxy groups polycyclic
    • C07C49/513—Saturated compounds containing a keto group being part of a ring containing hydroxy groups polycyclic a keto group being part of a condensed ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
    • C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
    • C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychology (AREA)
  • Psychiatry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hospice & Palliative Care (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PL05798253T 2004-09-07 2005-08-19 Nowe pochodne 3,5-seko-4-norcholestanowe i ich zastosowanie PL1786759T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0409436A FR2874923B1 (fr) 2004-09-07 2004-09-07 Application a titre de medicaments de derives du 3, 5-seco-4-nor-cholestane, compositions pharmaceutiques les renfermant, nouveaux derives et leur procede de preparation
EP05798253A EP1786759B1 (fr) 2004-09-07 2005-08-19 Nouveaux derives du 3,5-seco-4-nor-cholestane et leurs utilisations
PCT/FR2005/002116 WO2006027454A1 (fr) 2004-09-07 2005-08-19 Nouveaux derives du 3,5-seco-4-nor-cholestane et leurs utilisations

Publications (1)

Publication Number Publication Date
PL1786759T3 true PL1786759T3 (pl) 2012-11-30

Family

ID=34949389

Family Applications (1)

Application Number Title Priority Date Filing Date
PL05798253T PL1786759T3 (pl) 2004-09-07 2005-08-19 Nowe pochodne 3,5-seko-4-norcholestanowe i ich zastosowanie

Country Status (16)

Country Link
US (1) US9045393B2 (pl)
EP (1) EP1786759B1 (pl)
JP (1) JP5350630B2 (pl)
KR (1) KR101190464B1 (pl)
CN (1) CN101018762B (pl)
AU (1) AU2005281640B2 (pl)
BR (1) BRPI0514792A (pl)
CA (1) CA2576393C (pl)
DK (1) DK1786759T3 (pl)
ES (1) ES2390462T3 (pl)
FR (1) FR2874923B1 (pl)
IL (1) IL181216A (pl)
MX (1) MX2007002531A (pl)
PL (1) PL1786759T3 (pl)
RU (1) RU2398764C2 (pl)
WO (1) WO2006027454A1 (pl)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2874923B1 (fr) 2004-09-07 2006-10-27 Trophos Sa Application a titre de medicaments de derives du 3, 5-seco-4-nor-cholestane, compositions pharmaceutiques les renfermant, nouveaux derives et leur procede de preparation
FR2898272B1 (fr) * 2006-03-09 2008-07-04 Trophos Sa Utilisation de derives du 3,5-seco-4-nor-cholestrane pour l'obtention d'un medicament cytoprotecteur
FR2919180B1 (fr) * 2007-07-25 2009-11-27 Trophos Utilisation d'au moins un derive oxime de la cholest-4-en-3-one comme antioxydants
FR2919182B1 (fr) * 2007-07-25 2009-11-13 Trophos Utilisation d'au moins un derive oxime du 3,5-seco-4-nor-cholestane comme antioxydants
FR2940650B1 (fr) * 2008-12-29 2017-01-27 Trophos Nouveaux derives d'oxime du 3,5-seco-4-nor-cholestane, compositions pharmaceutiques les renfermant,et procede de preparation
WO2012069150A2 (en) 2010-11-22 2012-05-31 Powerpore Gmbh Cytoprotectant agents for the prevention of drug-associated side-effects
FR2979239A1 (fr) 2011-08-25 2013-03-01 Trophos Liposome comprenant au moins un derive de cholesterol

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2883424A (en) * 1956-06-20 1959-04-21 Monsanto Chemicals Dihydroxy steroid derivatives and method of preparing same
US5646188A (en) * 1995-07-05 1997-07-08 Teva Pharmaceutical Industries, Ltd. Polyamine derivatives of 1-aminoindan
GB0117326D0 (en) * 2001-07-16 2001-09-05 Univ Aberdeen Napthoquinone-type inhibitors of protein aggregation
JP4970932B2 (ja) * 2003-03-11 2012-07-11 トロフォ コレスト−４−エン−３−オンの誘導体の医薬としての使用、これらを含む医薬組成物、新規誘導体及びそれらの製造方法
FR2874923B1 (fr) 2004-09-07 2006-10-27 Trophos Sa Application a titre de medicaments de derives du 3, 5-seco-4-nor-cholestane, compositions pharmaceutiques les renfermant, nouveaux derives et leur procede de preparation
FR2894968B1 (fr) * 2005-12-20 2008-02-22 Trophos Sa Nouveaux derives de l'oxime de cholest-4-en-3-one, compositions pharmaceutiques les renfermant, et procede de preparation
FR2898272B1 (fr) * 2006-03-09 2008-07-04 Trophos Sa Utilisation de derives du 3,5-seco-4-nor-cholestrane pour l'obtention d'un medicament cytoprotecteur
FR2899108B1 (fr) * 2006-03-31 2012-02-03 Trophos Utilisation de derives du cholest-4-en-3-one pour l'obtention d'un medicament cytoprotecteur
FR2914188B1 (fr) * 2007-03-28 2012-06-22 Trophos Nouvelle composition a base d'oxime de cholest-4-en-3-one
FR2919182B1 (fr) * 2007-07-25 2009-11-13 Trophos Utilisation d'au moins un derive oxime du 3,5-seco-4-nor-cholestane comme antioxydants
FR2919180B1 (fr) * 2007-07-25 2009-11-27 Trophos Utilisation d'au moins un derive oxime de la cholest-4-en-3-one comme antioxydants
AU2008348717B2 (en) * 2007-10-30 2013-09-19 Trophos Novel composition for treating the side effects of anticancer treatments
FR2934596B1 (fr) * 2008-07-30 2015-04-10 Trophos Nouveaux derives de l'oxime de cholest-4-en-3-one, compositions pharmaceutiques les renfermant, et procede de preparation
FR2940650B1 (fr) * 2008-12-29 2017-01-27 Trophos Nouveaux derives d'oxime du 3,5-seco-4-nor-cholestane, compositions pharmaceutiques les renfermant,et procede de preparation

Also Published As

Publication number Publication date
FR2874923A1 (fr) 2006-03-10
CA2576393A1 (fr) 2006-03-16
RU2007112950A (ru) 2008-10-20
AU2005281640B2 (en) 2011-02-03
RU2398764C2 (ru) 2010-09-10
US9045393B2 (en) 2015-06-02
EP1786759B1 (fr) 2012-07-04
KR101190464B1 (ko) 2012-10-12
AU2005281640A1 (en) 2006-03-16
DK1786759T3 (da) 2012-10-15
KR20070101218A (ko) 2007-10-16
BRPI0514792A (pt) 2008-06-24
JP5350630B2 (ja) 2013-11-27
MX2007002531A (es) 2007-05-23
IL181216A (en) 2013-07-31
FR2874923B1 (fr) 2006-10-27
EP1786759A1 (fr) 2007-05-23
JP2008512368A (ja) 2008-04-24
CN101018762B (zh) 2011-12-21
CN101018762A (zh) 2007-08-15
ES2390462T3 (es) 2012-11-13
CA2576393C (fr) 2013-06-11
WO2006027454A1 (fr) 2006-03-16
US20080275130A1 (en) 2008-11-06
IL181216A0 (en) 2007-07-04

Similar Documents

Publication Publication Date Title
PL1736160T3 (pl) Oligosacharydy alginianowe i ich pochodne oraz ich wytwarzanie i zastosowanie
AU2003284808A8 (en) The derivatives of pyridone and the use of them
IL180682A0 (en) N-hydroxamide derivatives, their preparation and use
IL181670A0 (en) Substituted phenylaminothiazoles and use thereof
IL180284A0 (en) 2-carbamide-4-phenylthiazole derivatives, preparation thereof and therapeutic use thereof
IL178402A0 (en) 1-amino-phthalazine derivatives, the preparation and the therapeutic use thereof
PL1694649T3 (pl) Pochodne 2-pirydynyloetylokarboksyamidu i ich zastosowanie jako fungicydów
ZA200606678B (en) 2-Pyridinylethylcarboxamide derivatives and their use as fungicides
IL163868A0 (en) Hermiasterlin derivatives and uses thereof
IL184008A0 (en) 4-cycloalkyl-substituted tetrahydrochinoline derivatives and use thereof as medicaments
ZA200703876B (en) 2-amido -4-phenylthiazole derivatives, the preparation and therapeutic use thereof
PL394604A1 (pl) Pochodna winyloazacykloalkanowa, jej zastosowanie oraz kompozycja farmaceutyczna
IL175817A0 (en) Benzoxazine derivatives and uses thereof
IL166821A0 (en) Novel 1,4-diazabicycloalkane derivatives their preparation and use
IL178765A0 (en) 2-pyridinylcycloalkylbenzamide derivatives and their use as fungicides
GB0316910D0 (en) Fluorocombretastatin and derivatives thereof
IL177632A0 (en) 2h or 3h-benzo[e]indazol-1-yle carbamate derivatives, the preparation and therapeutic use thereof
EP1810976A4 (en) BENZONAPHTHACENEGLYCOSIDE DERIVATIVE AND THE USE THEREOF
ZA200704806B (en) Novel betulin derivatives, preparation thereof and use thereof
GB0307231D0 (en) 7-Nitroindoline derivatives and their uses
ZA200704650B (en) 4-cycloalkyl-substituted tetrahydrochinoline derivatives and use thereof as medicaments
EP1829860A4 (en) 9,10-SECOPREGNANDERIVAT AND MEDICINE
IL180484A0 (en) 4-arylmorpholin-3-one derivatives, preparation and therapeutic use thereof
IL176969A0 (en) Novel long-working beta-2-agonists and use thereof as medicaments
GB0311166D0 (en) Composition and use