PL1809270T3 - Kwas 5,6,7-trihydroksyheptanowy i jego analogi do leczenia chorób oczu i chorób związanych z odpowiedziami hiperproliferacyjnymi i angiogenicznymi - Google Patents
Kwas 5,6,7-trihydroksyheptanowy i jego analogi do leczenia chorób oczu i chorób związanych z odpowiedziami hiperproliferacyjnymi i angiogenicznymiInfo
- Publication number
- PL1809270T3 PL1809270T3 PL05824279T PL05824279T PL1809270T3 PL 1809270 T3 PL1809270 T3 PL 1809270T3 PL 05824279 T PL05824279 T PL 05824279T PL 05824279 T PL05824279 T PL 05824279T PL 1809270 T3 PL1809270 T3 PL 1809270T3
- Authority
- PL
- Poland
- Prior art keywords
- diseases
- analogs
- hyperproliferative
- treatment
- angiogenic responses
- Prior art date
Links
- AKGMFVVQMGQGBO-UHFFFAOYSA-N 5,6,7-trihydroxyheptanoic acid Chemical compound OCC(O)C(O)CCCC(O)=O AKGMFVVQMGQGBO-UHFFFAOYSA-N 0.000 title abstract 2
- 208000022873 Ocular disease Diseases 0.000 title abstract 2
- 201000010099 disease Diseases 0.000 title abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 2
- 230000006427 angiogenic response Effects 0.000 title 1
- 230000003463 hyperproliferative effect Effects 0.000 title 1
- 230000033115 angiogenesis Effects 0.000 abstract 1
- 230000001413 cellular effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Ophthalmology & Optometry (AREA)
- Diabetes (AREA)
- Emergency Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US62620904P | 2004-11-09 | 2004-11-09 | |
| EP05824279A EP1809270B1 (en) | 2004-11-09 | 2005-11-08 | 5,6,7-trihydroxyheptanoic acid and analogs for the treatment of ocular diseases and diseases associated with hyperproliferative and angiogenic responses |
| PCT/US2005/040392 WO2006052950A1 (en) | 2004-11-09 | 2005-11-08 | 5,6,7-trihydroxyheptanoic acid and analogs for the treatment of ocular diseases and diseases associated with hyperproliferative and angiogenic responses |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL1809270T3 true PL1809270T3 (pl) | 2010-08-31 |
Family
ID=35809550
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL05824279T PL1809270T3 (pl) | 2004-11-09 | 2005-11-08 | Kwas 5,6,7-trihydroksyheptanowy i jego analogi do leczenia chorób oczu i chorób związanych z odpowiedziami hiperproliferacyjnymi i angiogenicznymi |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US7879905B2 (pl) |
| EP (1) | EP1809270B1 (pl) |
| JP (3) | JP2008519763A (pl) |
| KR (1) | KR101237534B1 (pl) |
| CN (1) | CN101052387A (pl) |
| AT (1) | ATE461696T1 (pl) |
| AU (1) | AU2005304733B2 (pl) |
| BR (1) | BRPI0517972A (pl) |
| CA (1) | CA2584286C (pl) |
| CY (1) | CY1110644T1 (pl) |
| DE (1) | DE602005020178D1 (pl) |
| DK (1) | DK1809270T3 (pl) |
| ES (1) | ES2340786T3 (pl) |
| MX (1) | MX2007004622A (pl) |
| PL (1) | PL1809270T3 (pl) |
| PT (1) | PT1809270E (pl) |
| SI (1) | SI1809270T1 (pl) |
| WO (1) | WO2006052950A1 (pl) |
| ZA (1) | ZA200703992B (pl) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7879905B2 (en) * | 2004-11-09 | 2011-02-01 | Alcon, Inc. | 5,6,7-trihydroxyheptanoic acid and analogs for the treatment of ocular diseases and diseases associated with hyperproliferative and angiogenic responses |
| US20060154981A1 (en) * | 2005-01-12 | 2006-07-13 | Alcon, Inc. | Method of reducing intraocular pressure and treating glaucoma |
| US7687539B1 (en) | 2005-11-07 | 2010-03-30 | Alcon Research, Ltd. | Method of treating ocular allergy |
| CA2668645A1 (en) * | 2006-11-07 | 2008-05-15 | Alcon Research, Ltd. | Method of treating asthma, allergic rhinitis, and skin disorders |
| BR112012013303A2 (pt) * | 2009-12-04 | 2016-03-01 | Euclid Systems Corp | composições farmacêuticas e respectivos usos |
| WO2011096941A1 (en) * | 2010-02-08 | 2011-08-11 | Alcon Research, Ltd. | Method of treating ocular allergy |
| JP2013521230A (ja) * | 2010-02-25 | 2013-06-10 | アルコン リサーチ， リミテッド | 角膜創傷治癒を促進する方法 |
| WO2020210652A1 (en) | 2019-04-10 | 2020-10-15 | Neovasc Tiara Inc. | Prosthetic valve with natural blood flow |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4975537A (en) | 1985-10-23 | 1990-12-04 | The Upjohn Company | Δ9(11) -angiostatic steroids |
| US4771042A (en) | 1985-11-25 | 1988-09-13 | The Upjohn Company | Inhibition of angiogenesis involving the coadministration of steroids with heparin or heparin fragments |
| JP2834512B2 (ja) * | 1990-01-30 | 1998-12-09 | 帝人株式会社 | リポキシン誘導体を有効成分とする疾患治療剤 |
| US6048897A (en) * | 1993-06-15 | 2000-04-11 | Brigham And Women's Hospital | Lipoxin compounds and their use in treating cell proliferative disorders |
| US5441951A (en) | 1994-06-15 | 1995-08-15 | Brigham & Women's Hospital | Lipoxin compounds |
| JPH08268886A (ja) | 1995-03-31 | 1996-10-15 | Eisai Co Ltd | 血管新生抑制剤 |
| ES2215752T3 (es) * | 1999-11-09 | 2004-10-16 | Alcon, Inc | Lipoxina a4 y analogos para el tratamiento del ojo seco. |
| AR030345A1 (es) | 2000-08-14 | 2003-08-20 | Alcon Inc | Metodo de tratamiento de desordenes relacionados con angiogenesis |
| PT1406698E (pt) * | 2001-03-02 | 2009-01-12 | Brigham & Womens Hospital | Análogos de lipoxina como novos inibidores da angiogénese |
| CN100522147C (zh) | 2004-05-14 | 2009-08-05 | 爱尔康公司 | 5,6,7-三羟基庚酸及其类似物在制备治疗干眼病和眼色素层炎药物中的应用 |
| US7879905B2 (en) * | 2004-11-09 | 2011-02-01 | Alcon, Inc. | 5,6,7-trihydroxyheptanoic acid and analogs for the treatment of ocular diseases and diseases associated with hyperproliferative and angiogenic responses |
-
2005
- 2005-11-08 US US11/268,968 patent/US7879905B2/en not_active Expired - Fee Related
- 2005-11-08 PT PT05824279T patent/PT1809270E/pt unknown
- 2005-11-08 MX MX2007004622A patent/MX2007004622A/es active IP Right Grant
- 2005-11-08 CN CNA200580037399XA patent/CN101052387A/zh active Pending
- 2005-11-08 PL PL05824279T patent/PL1809270T3/pl unknown
- 2005-11-08 SI SI200530999T patent/SI1809270T1/sl unknown
- 2005-11-08 CA CA2584286A patent/CA2584286C/en not_active Expired - Fee Related
- 2005-11-08 DE DE602005020178T patent/DE602005020178D1/de not_active Expired - Lifetime
- 2005-11-08 WO PCT/US2005/040392 patent/WO2006052950A1/en not_active Ceased
- 2005-11-08 ES ES05824279T patent/ES2340786T3/es not_active Expired - Lifetime
- 2005-11-08 EP EP05824279A patent/EP1809270B1/en not_active Expired - Lifetime
- 2005-11-08 AU AU2005304733A patent/AU2005304733B2/en not_active Ceased
- 2005-11-08 JP JP2007540158A patent/JP2008519763A/ja active Pending
- 2005-11-08 KR KR1020077010194A patent/KR101237534B1/ko not_active Expired - Fee Related
- 2005-11-08 AT AT05824279T patent/ATE461696T1/de active
- 2005-11-08 DK DK05824279.3T patent/DK1809270T3/da active
- 2005-11-08 ZA ZA200703992A patent/ZA200703992B/xx unknown
- 2005-11-08 BR BRPI0517972-6A patent/BRPI0517972A/pt not_active IP Right Cessation
-
2010
- 2010-05-28 CY CY20101100473T patent/CY1110644T1/el unknown
- 2010-12-14 US US12/967,141 patent/US20110082200A1/en not_active Abandoned
-
2012
- 2012-03-12 JP JP2012054606A patent/JP2012107073A/ja active Pending
-
2014
- 2014-07-25 JP JP2014151656A patent/JP2014198730A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2008519763A (ja) | 2008-06-12 |
| ZA200703992B (en) | 2009-08-26 |
| MX2007004622A (es) | 2007-06-11 |
| JP2014198730A (ja) | 2014-10-23 |
| PT1809270E (pt) | 2010-05-25 |
| KR20070083980A (ko) | 2007-08-24 |
| US20110082200A1 (en) | 2011-04-07 |
| EP1809270B1 (en) | 2010-03-24 |
| CY1110644T1 (el) | 2015-04-29 |
| HK1110768A1 (en) | 2008-07-25 |
| WO2006052950A1 (en) | 2006-05-18 |
| ATE461696T1 (de) | 2010-04-15 |
| JP2012107073A (ja) | 2012-06-07 |
| CA2584286C (en) | 2014-01-14 |
| DK1809270T3 (da) | 2010-06-14 |
| EP1809270A1 (en) | 2007-07-25 |
| CA2584286A1 (en) | 2006-05-18 |
| AU2005304733A1 (en) | 2006-05-18 |
| US7879905B2 (en) | 2011-02-01 |
| BRPI0517972A (pt) | 2008-10-21 |
| US20060099248A1 (en) | 2006-05-11 |
| SI1809270T1 (sl) | 2010-07-30 |
| DE602005020178D1 (de) | 2010-05-06 |
| CN101052387A (zh) | 2007-10-10 |
| AU2005304733B2 (en) | 2011-04-07 |
| KR101237534B1 (ko) | 2013-03-04 |
| ES2340786T3 (es) | 2010-06-09 |
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