PL1829874T3 - Tricykliczny związek i jego zastosowanie - Google Patents

Tricykliczny związek i jego zastosowanie

Info

Publication number
PL1829874T3
PL1829874T3 PL05820106T PL05820106T PL1829874T3 PL 1829874 T3 PL1829874 T3 PL 1829874T3 PL 05820106 T PL05820106 T PL 05820106T PL 05820106 T PL05820106 T PL 05820106T PL 1829874 T3 PL1829874 T3 PL 1829874T3
Authority
PL
Poland
Prior art keywords
tricyclic compound
tricyclic
compound
Prior art date
Application number
PL05820106T
Other languages
English (en)
Inventor
Junichiro Manako
Yoshifumi Kagamiishi
Masashi Kato
Kazuyuki Ohmoto
Original Assignee
Ono Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ono Pharmaceutical Co filed Critical Ono Pharmaceutical Co
Publication of PL1829874T3 publication Critical patent/PL1829874T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/438—The ring being spiro-condensed with carbocyclic or heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Immunology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL05820106T 2004-12-22 2005-12-21 Tricykliczny związek i jego zastosowanie PL1829874T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2004371033 2004-12-22
JP2005261914 2005-09-09
PCT/JP2005/023450 WO2006068164A1 (ja) 2004-12-22 2005-12-21 三環式化合物およびその用途
EP20050820106 EP1829874B1 (en) 2004-12-22 2005-12-21 Tricyclic compound and use thereof

Publications (1)

Publication Number Publication Date
PL1829874T3 true PL1829874T3 (pl) 2014-07-31

Family

ID=36601763

Family Applications (1)

Application Number Title Priority Date Filing Date
PL05820106T PL1829874T3 (pl) 2004-12-22 2005-12-21 Tricykliczny związek i jego zastosowanie

Country Status (8)

Country Link
US (4) US7964726B2 (pl)
EP (1) EP1829874B1 (pl)
JP (2) JP4997976B2 (pl)
DK (1) DK1829874T3 (pl)
ES (1) ES2459742T3 (pl)
PL (1) PL1829874T3 (pl)
PT (1) PT1829874E (pl)
WO (1) WO2006068164A1 (pl)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004113300A1 (ja) * 2003-06-23 2004-12-29 Ono Pharmaceutical Co., Ltd. 新規三環性複素環化合物
ES2459742T3 (es) * 2004-12-22 2014-05-12 Ono Pharmaceutical Co., Ltd. Compuesto tricíclico y uso del mismo
DE102006033114A1 (de) * 2006-07-18 2008-01-24 Grünenthal GmbH Spirocyclische Azaindol-Derivate
US8242294B2 (en) 2007-06-19 2012-08-14 Kythera Biopharmaceuticals, Inc. Synthetic bile acid compositions and methods
US20080318870A1 (en) 2007-06-19 2008-12-25 Kythera Biopharmaceuticals, Inc. Synthetic bile acid compositions and methods
JOP20180077A1 (ar) 2007-06-19 2019-01-30 Kythera Biopharmaceuticals Inc تركيبات وطرق لحمض صفراوي تخليقي
PH12012502447A1 (en) * 2010-07-06 2016-10-14 Ono Pharmaceutical Co Tetrahydrocarboline derivative
WO2015190568A1 (ja) * 2014-06-12 2015-12-17 小野薬品工業株式会社 ストレス性疾患の予防および/または治療用医薬
US10092550B2 (en) 2014-10-21 2018-10-09 Ions Pharmaceutical S.À R.L. Therapeutic compositions containing curcumin, harmine, and isovanillin components, and methods of use thereof
US9907786B2 (en) 2014-10-21 2018-03-06 Ions Pharmaceutical S.À R.L. Therapeutic compositions containing harmine and isovanillin components, and methods of use thereof
TW201630604A (zh) * 2015-01-09 2016-09-01 小野藥品工業股份有限公司 纖維肌痛症之預防及/或治療劑
US9853612B1 (en) 2017-03-23 2017-12-26 Globalfoundries Inc. Peaking amplifier frequency tuning
US10033334B1 (en) 2017-03-23 2018-07-24 Globalfoundries Inc. Peaking amplifier frequency tuning
US12129265B2 (en) 2020-07-21 2024-10-29 Ankh Life Sciences Limited Therapeutic agents and uses thereof
JP2024502270A (ja) 2020-12-23 2024-01-18 リキュリウム アイピー ホールディングス リミテッド ライアビリティー カンパニー エストロゲン受容体調節薬

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1431702A (fr) 1964-11-23 1966-03-18 Sames Mach Electrostat Perfectionnements à l'élaboration des échantillons ou étalons utilisés en analyse radiochimique
US3959470A (en) * 1972-11-28 1976-05-25 Mikhail Davidovich Mashkovsky Psychotropic medicinal preparation
SU788471A1 (ru) 1972-11-28 1981-12-30 Всесоюзный Научно-Исследовательский Химико-Фармацевтический Институт Им.С.Орджоникидзе Психотропное средство дл лечени депрессивных состо ний "инказан
US4336260A (en) * 1977-12-08 1982-06-22 The Dow Chemical Company Method and compositions using 1-aryl-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid for treating depression
EP0357122A3 (en) * 1988-08-29 1991-10-23 Duphar International Research B.V Use of beta-carbolines, their bio-isosteric benzofuran and benzothiophene analogues for the manufacture of a medicament having cytostatic properties
JPH03287586A (ja) * 1990-04-02 1991-12-18 Taisho Pharmaceut Co Ltd テトラヒドロ―β―カルボリン誘導体
GB9401090D0 (en) 1994-01-21 1994-03-16 Glaxo Lab Sa Chemical compounds
US5403851A (en) 1994-04-05 1995-04-04 Interneuron Pharmaceuticals, Inc. Substituted tryptamines, phenalkylamines and related compounds
FR2724384B1 (fr) * 1994-09-14 1999-04-16 Cemaf Nouveaux derives de la 3,4-dihydro beta-carboline agonistes de la melatonine, leur procede de preparation et leur utilisation a titre de medicament
PL329875A1 (en) 1996-05-10 1999-04-12 Icos Corp Derivatives of carbolin
JP4346685B2 (ja) * 1996-10-21 2009-10-21 ユーロビタ アクティーゼルスカブ パルテニウム・インテグリフォリウム又はその部分若しくはそのエキス又はその成分を含有する医薬組成物、かかる植物材料の医薬製造のための使用、及びパルテニウム・インテグリフォリウムのエキスの製造方法
DE19712201A1 (de) 1997-03-24 1998-10-01 Bodenseewerk Geraetetech Mikromechanische Spiegel-Anordnung
US6043252A (en) * 1997-05-05 2000-03-28 Icos Corporation Carboline derivatives
ES2188184T3 (es) 1998-06-12 2003-06-16 Sod Conseils Rech Applic Compuestos de beta-carbolinas.
CA2339630C (en) 1998-09-16 2006-05-23 Icos Corporation Carboline derivatives as cgmp phosphodiesterase inhibitors
FR2796644B1 (fr) 1999-07-23 2001-09-07 Adir Nouveaux derives de beta-carboline, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
UA74826C2 (en) 2000-05-17 2006-02-15 Ortho Mcneil Pharm Inc ?-carboline derivatives as phosphodiesterase inhibitors
US7488742B2 (en) * 2000-06-15 2009-02-10 Schering Corporation Thrombin receptor antagonists
ATE300543T1 (de) 2000-06-26 2005-08-15 Lilly Icos Llc Kondensierte pyrazindionderivate als pde5 inhibitore
ES2294047T3 (es) 2000-12-28 2008-04-01 Ono Pharmaceutical Co., Ltd. Un compuesto de ciclopenta (d) pirazolo(1,5-a) pirimidina como antagonista del receptor de crf.
AU2002246728A1 (en) * 2001-02-12 2002-08-28 Lilly Icos Llc Carboline derivatives
ES2272695T3 (es) * 2001-02-12 2007-05-01 Lilly Icos Llc Derivados de carbolina.
GB0108337D0 (en) 2001-04-03 2001-05-23 Novartis Ag Organic compounds
ES2278956T3 (es) 2001-04-25 2007-08-16 Lilly Icos Llc Derivados de carbolina como inhibidores de fosfodiesterasa 5 (pde5) para el tratamiento de enfermedades cardiovasculares y de la disfuncion erectil.
EP1438973A4 (en) 2001-10-05 2005-07-13 Ono Pharmaceutical Co MEANS FOR THE TREATMENT OF STRESS-RELATED DISEASES WITH MITOCHONDRIENE BENZODIAZEPINE RECEPTOR ANTAGONISTS
SE520453C2 (sv) * 2001-11-01 2003-07-15 Alfa Laval Corp Ab En apparat för samtidig rening av en vätska och en gas
AU2003211951A1 (en) * 2002-02-14 2003-09-04 Ono Pharmaceutical Co., Ltd. N-carbamoyl nitrogen-containing fused ring compounds and drugs containing these compounds as the active ingredient
TWI329111B (en) 2002-05-24 2010-08-21 X Ceptor Therapeutics Inc Azepinoindole and pyridoindole derivatives as pharmaceutical agents
WO2004113300A1 (ja) 2003-06-23 2004-12-29 Ono Pharmaceutical Co., Ltd. 新規三環性複素環化合物
US7855295B2 (en) 2004-01-23 2010-12-21 Novartis Vaccines And Diagnostics, Inc. Tetrahydrocarboline compounds as anticancer agents
EA201200555A1 (ru) 2004-03-15 2013-01-30 ПиТиСи ТЕРАПЬЮТИКС, ИНК. Производные карболина, полезные в ингибировании ангиогенеза
US7403851B2 (en) * 2004-09-30 2008-07-22 Navteq North America, Llc Method of operating a navigation system to report effects of updated portions of a geographic database
ES2459742T3 (es) * 2004-12-22 2014-05-12 Ono Pharmaceutical Co., Ltd. Compuesto tricíclico y uso del mismo

Also Published As

Publication number Publication date
US20110207700A1 (en) 2011-08-25
EP1829874A1 (en) 2007-09-05
EP1829874B1 (en) 2014-02-12
DK1829874T3 (da) 2014-05-12
JP5652417B2 (ja) 2015-01-14
US8476293B2 (en) 2013-07-02
WO2006068164A1 (ja) 2006-06-29
PT1829874E (pt) 2014-04-10
US20130252993A1 (en) 2013-09-26
JPWO2006068164A1 (ja) 2008-06-12
US20150105415A1 (en) 2015-04-16
JP4997976B2 (ja) 2012-08-15
ES2459742T3 (es) 2014-05-12
JP2012126737A (ja) 2012-07-05
US20080114012A1 (en) 2008-05-15
EP1829874A4 (en) 2010-01-06
US7964726B2 (en) 2011-06-21
US8952158B2 (en) 2015-02-10

Similar Documents

Publication Publication Date Title
EP1802588A4 (en) SUBSTITUTED AMINOPYRIMIDONE AND APPLICATIONS THEREOF
ZA200701820B (en) Substituted phenylaminothiazoles and use thereof
EP1790639A4 (en) A BASIC GROUP CONNECTING AND APPLYING THEREOF
EP1829874A4 (en) TRICYCLIC COMPOUND AND ITS USE
PL1755392T3 (pl) Związki izoflawonoidowe i ich zastosowanie
EP1778214A4 (en) NEW BIPHENYL COMPOUNDS AND THEIR USE
IL179497A0 (en) Carboranylporphyrins and uses thereof
PL2215908T3 (pl) 2-alkilo-cykloalk(en)ylo-karboksamidy i ich zastosowanie jako fungicydów
IL180365A0 (en) Carboranylporphyrins and uses thereof
GB0407301D0 (en) Use
ZA200609075B (en) Isoflavonoid compounds and use thereof
GB0410015D0 (en) Use
EP1810976A4 (en) BENZONAPHTHACENEGLYCOSIDE DERIVATIVE AND THE USE THEREOF
GB0412878D0 (en) Use
GB0427723D0 (en) Compounds and their use
GB0407628D0 (en) Compounds and their use
GB0409379D0 (en) Compounds and their use
GB0423234D0 (en) Compounds and their use
GB0402903D0 (en) Compounds and their use
GB0403617D0 (en) Compounds and their use
GB0410831D0 (en) Compounds and their use
GB0409377D0 (en) Compounds and their use
GB0410832D0 (en) Compounds and their use
GB0401244D0 (en) Compounds and their use
GB0410114D0 (en) Compounds and their use