PL1858851T3 - Sposób otrzymywania amorficznej lerkanidypiny - Google Patents
Sposób otrzymywania amorficznej lerkanidypinyInfo
- Publication number
- PL1858851T3 PL1858851T3 PL05817765T PL05817765T PL1858851T3 PL 1858851 T3 PL1858851 T3 PL 1858851T3 PL 05817765 T PL05817765 T PL 05817765T PL 05817765 T PL05817765 T PL 05817765T PL 1858851 T3 PL1858851 T3 PL 1858851T3
- Authority
- PL
- Poland
- Prior art keywords
- preparing method
- amorphous lercanidipine
- lercanidipine
- amorphous
- preparing
- Prior art date
Links
- ZDXUKAKRHYTAKV-UHFFFAOYSA-N lercanidipine Chemical compound COC(=O)C1=C(C)NC(C)=C(C(=O)OC(C)(C)CN(C)CCC(C=2C=CC=CC=2)C=2C=CC=CC=2)C1C1=CC=CC([N+]([O-])=O)=C1 ZDXUKAKRHYTAKV-UHFFFAOYSA-N 0.000 title 1
- 229960004294 lercanidipine Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B63/00—Purification; Separation; Stabilisation; Use of additives
- C07B63/04—Use of additives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20040086179 | 2004-10-27 | ||
| KR1020050031041A KR100651212B1 (ko) | 2004-10-27 | 2005-04-14 | 무정형 레르카니디핀의 제조방법 |
| PCT/KR2005/003576 WO2006046830A1 (en) | 2004-10-27 | 2005-10-26 | Preparing method for amorphous lercanidipine |
| EP05817765.0A EP1858851B1 (en) | 2004-10-27 | 2005-10-26 | Preparing method for amorphous lercanidipine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL1858851T3 true PL1858851T3 (pl) | 2015-11-30 |
Family
ID=36228043
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL05817765T PL1858851T3 (pl) | 2004-10-27 | 2005-10-26 | Sposób otrzymywania amorficznej lerkanidypiny |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP1858851B1 (pl) |
| KR (1) | KR100651212B1 (pl) |
| CA (1) | CA2624934C (pl) |
| CY (1) | CY1116752T1 (pl) |
| DK (1) | DK1858851T3 (pl) |
| ES (1) | ES2546930T3 (pl) |
| HR (1) | HRP20150989T1 (pl) |
| HU (1) | HUE025506T2 (pl) |
| PL (1) | PL1858851T3 (pl) |
| PT (1) | PT1858851E (pl) |
| RS (1) | RS54174B1 (pl) |
| SI (1) | SI1858851T1 (pl) |
| WO (1) | WO2006046830A1 (pl) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR052918A1 (es) | 2005-02-25 | 2007-04-11 | Recordati Ireland Ltd | Clorhidrato de lercanidipina amorfo |
| US20100104649A1 (en) * | 2007-03-05 | 2010-04-29 | Actavis Group Ptc Ehf | Lercanidipine Hydrochloride Polymorphs and an Improved Process for Preparation of 1,1,N-Trimethyl-N-(3,3-Diphenylpropyl)-2-Aminoethyl Acetoacetate |
| CN102531999B (zh) * | 2011-12-16 | 2014-02-26 | 华润赛科药业有限责任公司 | 无定形盐酸乐卡地平及其制备方法 |
| CN102558032B (zh) * | 2011-12-16 | 2014-02-26 | 华润赛科药业有限责任公司 | 一种无定形盐酸乐卡地平及其制备方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8403866D0 (en) | 1984-02-14 | 1984-03-21 | Recordati Chem Pharm | Diphenylalkylaminoalkyl esters |
| US5767136A (en) | 1995-05-12 | 1998-06-16 | Recordati, S.A. Chemical And Pharmaceutical Company | 1,4-Dihydropyridines useful for prevention or reduction of atherosclerotic lesions on arterial walls |
| US5696139A (en) | 1995-05-12 | 1997-12-09 | Recordati S.A., Chemical And Pharmaceutical Company | Use of S-enantiomers of 1,4-dihydropyridine derivatives for treating heart failure |
| ITMI20011727A1 (it) | 2001-08-06 | 2003-02-06 | Recordati Ind Chimica E Farma | Solvati della lercanidipina cloridrato e nuove forme cristalline della lercanidipina cloridrato ottenute da essi |
| US6852737B2 (en) * | 2001-08-06 | 2005-02-08 | Recordati Ireland Limited | Crude and crystalline forms of lercanidipine hydrochloride |
| AR053023A1 (es) * | 2005-02-25 | 2007-04-18 | Recordati Ireland Ltd | Base libre de lercanidipina, metodos para su preparacion y composiciones farmaceuticas que las contienen |
-
2005
- 2005-04-14 KR KR1020050031041A patent/KR100651212B1/ko not_active Expired - Fee Related
- 2005-10-26 EP EP05817765.0A patent/EP1858851B1/en not_active Expired - Lifetime
- 2005-10-26 WO PCT/KR2005/003576 patent/WO2006046830A1/en not_active Ceased
- 2005-10-26 PT PT58177650T patent/PT1858851E/pt unknown
- 2005-10-26 CA CA2624934A patent/CA2624934C/en not_active Expired - Fee Related
- 2005-10-26 RS RS20150564A patent/RS54174B1/sr unknown
- 2005-10-26 SI SI200531995T patent/SI1858851T1/sl unknown
- 2005-10-26 HU HUE05817765A patent/HUE025506T2/en unknown
- 2005-10-26 ES ES05817765.0T patent/ES2546930T3/es not_active Expired - Lifetime
- 2005-10-26 PL PL05817765T patent/PL1858851T3/pl unknown
- 2005-10-26 HR HRP20150989TT patent/HRP20150989T1/hr unknown
- 2005-10-26 DK DK05817765.0T patent/DK1858851T3/en active
-
2015
- 2015-09-14 CY CY20151100794T patent/CY1116752T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SI1858851T1 (sl) | 2015-11-30 |
| KR100651212B1 (ko) | 2006-12-01 |
| ES2546930T3 (es) | 2015-09-30 |
| EP1858851A4 (en) | 2009-12-30 |
| EP1858851B1 (en) | 2015-06-24 |
| CA2624934C (en) | 2013-04-23 |
| EP1858851A1 (en) | 2007-11-28 |
| RS54174B1 (sr) | 2015-12-31 |
| WO2006046830A1 (en) | 2006-05-04 |
| CY1116752T1 (el) | 2017-03-15 |
| KR20060045705A (ko) | 2006-05-17 |
| DK1858851T3 (en) | 2015-09-14 |
| HRP20150989T1 (hr) | 2015-10-23 |
| CA2624934A1 (en) | 2006-05-04 |
| PT1858851E (pt) | 2015-10-12 |
| HUE025506T2 (en) | 2016-02-29 |
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