PL1858930T3 - Sposób wytwarzania kompleksów trójwartościowego żelaza z mono-, di- oraz polisacharydami - Google Patents

Sposób wytwarzania kompleksów trójwartościowego żelaza z mono-, di- oraz polisacharydami

Info

Publication number: PL1858930T3
Authority: PL; Poland
Prior art keywords: trivalent iron; mono; preparation; iron complexes; sugar
Prior art date: 2005-03-15

Application number

PL06765408T

Other languages

English (en)

Other versions

PL1858930T5 (pl

Inventor

Egidio Marchi

Mauro Montorsi

Stefania Sacchi

Original Assignee

Biofer Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-03-15

Filing date

2006-03-14

Publication date

2011-12-30

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36825770&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL1858930(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2006-03-14 Application filed by Biofer Spa filed Critical Biofer Spa

2011-12-30 Publication of PL1858930T3 publication Critical patent/PL1858930T3/pl

2024-12-02 Publication of PL1858930T5 publication Critical patent/PL1858930T5/pl

Links

235000000346 sugar Nutrition 0.000 title abstract 4
150000002505 iron Chemical class 0.000 title abstract 2
238000000034 method Methods 0.000 title abstract 2
229920001282 polysaccharide Polymers 0.000 title abstract 2
239000005017 polysaccharide Substances 0.000 title abstract 2
-1 polysaccharide sugars Chemical class 0.000 title abstract 2
238000002360 preparation method Methods 0.000 title abstract 2
WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 2
GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 2
229910052794 bromium Inorganic materials 0.000 abstract 2
WQYVRQLZKVEZGA-UHFFFAOYSA-N hypochlorite Chemical compound Cl[O-] WQYVRQLZKVEZGA-UHFFFAOYSA-N 0.000 abstract 2
239000000243 solution Substances 0.000 abstract 2
230000004913 activation Effects 0.000 abstract 1
239000007864 aqueous solution Substances 0.000 abstract 1
238000006243 chemical reaction Methods 0.000 abstract 1
238000010668 complexation reaction Methods 0.000 abstract 1
FWZTTZUKDVJDCM-CEJAUHOTSA-M disodium;(2r,3r,4s,5s,6r)-2-[(2s,3s,4s,5r)-3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol;iron(3+);oxygen(2-);hydroxide;trihydrate Chemical compound O.O.O.[OH-].[O-2].[O-2].[O-2].[O-2].[O-2].[O-2].[O-2].[O-2].[Na+].[Na+].[Fe+3].[Fe+3].[Fe+3].[Fe+3].[Fe+3].O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 FWZTTZUKDVJDCM-CEJAUHOTSA-M 0.000 abstract 1
238000010438 heat treatment Methods 0.000 abstract 1
238000011065 in-situ storage Methods 0.000 abstract 1
230000003647 oxidation Effects 0.000 abstract 1
238000007254 oxidation reaction Methods 0.000 abstract 1
238000000746 purification Methods 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
230000006641 stabilisation Effects 0.000 abstract 1
238000011105 stabilization Methods 0.000 abstract 1
238000000108 ultra-filtration Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H23/00—Compounds containing boron, silicon or a metal, e.g. chelates or vitamin B12
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B30/00—Preparation of starch, degraded or non-chemically modified starch, amylose, or amylopectin
- C08B30/12—Degraded, destructured or non-chemically modified starch, e.g. mechanically, enzymatically or by irradiation; Bleaching of starch
- C08B30/18—Dextrin, e.g. yellow canari, white dextrin, amylodextrin or maltodextrin; Methods of depolymerisation, e.g. by irradiation or mechanically
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B31/00—Preparation of derivatives of starch
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
- C08B37/0021—Dextran, i.e. (alpha-1,4)-D-glucan; Derivatives thereof, e.g. Sephadex, i.e. crosslinked dextran

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Biochemistry (AREA)
Engineering & Computer Science (AREA)
Polymers & Plastics (AREA)
Materials Engineering (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
General Health & Medical Sciences (AREA)
Biotechnology (AREA)
Genetics & Genomics (AREA)
Crystallography & Structural Chemistry (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

PL06765408.7T 2005-03-15 2006-03-14 Sposób wytwarzania kompleksów trójwartościowego żelaza z mono-, di- oraz polisacharydami PL1858930T5 (pl)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
IT000056A ITMO20050056A1 (it)	2005-03-15	2005-03-15	Processo per la preparazione di complessi del ferro trivalente con zuccheri mono-, di- e polisaccaridi.
PCT/IB2006/000560 WO2006111802A1 (en)	2005-03-15	2006-03-14	Process for the preparation of trivalent iron complexes with mono-, di- and polysaccharide sugars
EP06765408.7A EP1858930B2 (en)	2005-03-15	2006-03-14	Process for the preparation of trivalent iron complexes with mono-, di- and polysaccharide sugars

Publications (2)

Publication Number	Publication Date
PL1858930T3 true PL1858930T3 (pl)	2011-12-30
PL1858930T5 PL1858930T5 (pl)	2024-12-02

Family

ID=36825770

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL06765408.7T PL1858930T5 (pl)	2005-03-15	2006-03-14	Sposób wytwarzania kompleksów trójwartościowego żelaza z mono-, di- oraz polisacharydami

Country Status (12)

Country	Link
US (2)	US8759320B2 (pl)
EP (1)	EP1858930B2 (pl)
AT (1)	ATE517127T1 (pl)
CA (1)	CA2601646C (pl)
CY (1)	CY1111885T1 (pl)
DK (1)	DK1858930T3 (pl)
ES (1)	ES2370942T5 (pl)
IT (1)	ITMO20050056A1 (pl)
PL (1)	PL1858930T5 (pl)
PT (1)	PT1858930E (pl)
SI (1)	SI1858930T2 (pl)
WO (1)	WO2006111802A1 (pl)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
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EP1997833A1 (de) *	2007-05-29	2008-12-03	Vifor (International) Ag	Wasserlösliche Eisen-Kohlenhydratderivat-Komplexe, deren Herstellung und diese enthaltende Arzneimittel
LT3156075T (lt)	2009-03-25	2021-01-11	Pharmacosmos Holding A/S	Oligosacharidas ir jo paruošimo būdas
US8536106B2 (en)	2010-04-14	2013-09-17	Ecolab Usa Inc.	Ferric hydroxycarboxylate as a builder
IT1405688B1 (it) *	2010-06-09	2014-01-24	Biofer Spa	Nuovi complessi a basso peso molecolare tra ferro ed acido maltobionico, uso di questi per la somministrazione intramuscolare o sottocutanea nella terapia di stati anemici, e nuove composizioni farmaceutiche adatte a questi usi.
CN103059072B (zh) *	2013-01-18	2015-08-26	常州工程职业技术学院	一种绿色环保的蔗糖铁原料药的制备方法
CN103641875B (zh) *	2013-11-20	2017-10-24	上海医药集团青岛国风药业股份有限公司	一种多糖铁复合物的制备工艺及其质量检测方法
EP3157516A4 (en)	2014-06-22	2017-12-13	Dexcel Pharma Technologies Ltd.	Pharmaceutical compositions comprising ferric citrate and methods for the production thereof
EP2997968A1 (en) *	2014-09-22	2016-03-23	Ioulia Tseti	Iron (III) hydroxide complexes with activated glucose syrups and process for preparing same
US10258647B2 (en)	2015-09-01	2019-04-16	Particle Dynamics International, Llc	Iron-polysaccharide complexes and methods for the preparation thereof
CN106543294A (zh) *	2015-09-18	2017-03-29	瑞普（天津）生物药业有限公司	一种右旋糖酐铁的制备方法
AU2018328052C1 (en) *	2017-09-11	2025-12-18	Pharmacosmos Holding A/S	Iron complex compounds for therapeutic use
HUE063182T2 (hu)	2019-02-28	2024-01-28	Renibus Therapeutics Inc	Újszerû vaskészítmények és elõállítási és felhasználási eljárásaik
CN110804107B (zh) *	2019-09-29	2021-08-31	山东金洋药业有限公司	一种使用右旋糖酐制备右旋糖酐铁水溶液的方法
CN115989849B (zh) *	2023-01-18	2024-11-08	中鲨动物保健品（厦门）有限公司	一种氨基酸多糖络（螯）合物的半湿法制备工艺
CN116138357A (zh) *	2023-02-27	2023-05-23	中国农业大学	一种宠物用饲料添加剂及其制备方法和应用

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DE461370C (de)	1925-06-13	1928-06-21	Chem Fab Vormals Sandoz	Verfahren zur Herstellung von Monocarbonsaeuren aus Aldosen
US2820740A (en) *	1953-02-27	1958-01-21	Benger Lab Ltd	Therapeutic preparations of iron
US2885393A (en) *	1956-02-24	1959-05-05	R K Laros Company	Dextran-iron complex and process for making same
GB1200902A (en) *	1967-05-13	1970-08-05	Fisons Pharmaceuticals Ltd	Iron-dextran complexes
US4180567A (en) *	1977-09-02	1979-12-25	Pharmachem Corporation	Iron preparations and methods of making and administering the same
US4370476A (en) *	1979-07-17	1983-01-25	Usher Thomas C	Dextran polycarboxylic acids, ferric hydroxide complexes
DE3026868C2 (de)	1980-07-16	1986-03-13	Laboratorien Hausmann AG, St. Gallen	Verfahren zur Herstellung von Eisen(III)hydroxid-Dextran-Komplexen und sie enthaltende pharmazeutische sterile wäßrige Lösung
US4788281A (en) *	1984-01-04	1988-11-29	Tosoni Anthony L	Dextran hexonic acid derivative, ferric hydroxide complex and method manufacture thereof
DE3422249A1 (de) *	1984-06-15	1985-12-19	Pfeifer & Langen, 5000 Köln	Wasserloesliches eisendextran und verfahren zu seiner herstellung
NL9001027A (nl) *	1990-04-27	1991-11-18	Tno	Werkwijze voor de bereiding van calciumbindende polycarboxyverbindingen op basis van polysacchariden, alsmede fosfaat-vervangers voor wasmiddelen op basis van deze polycarboxyverbindingen.
JP2000500175A (ja)	1995-11-09	2000-01-11	アボツト・ラボラトリーズ	結晶質鉄デキストランの製造方法
US5756715A (en) *	1996-11-08	1998-05-26	Abbott Laboratories	Process for making crystalline iron dextran
CA2195283C (en)	1997-01-16	2008-07-22	Thomas C. Usher	Process for manufacturing iron dextran using ultrafiltration
DK172860B1 (da) *	1998-03-25	1999-08-16	Pharmacosmos Holding As	Jerndextranforbindelse til anvendelse som komponent i et terapeutisk middel til forebyggelse af eller behandling af jernman
DK173138B1 (da) *	1998-11-20	2000-02-07	Pharmacosmos Holding As	Fremgangsmåde til fremstilling af en jerndextranforbindelse, jerndextranforbindelse fremstillet efter fremgangsmåden, farma
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DE10249552A1 (de)	2002-10-23	2004-05-13	Vifor (International) Ag	Wasserlösliche Eisen-Kohlenhydrat-Komplexe, deren Herstellung und diese enthaltende Arzneimittel
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US7442624B2 (en) *	2004-08-02	2008-10-28	Infineon Technologies Ag	Deep alignment marks on edge chips for subsequent alignment of opaque layers

2005
- 2005-03-15 IT IT000056A patent/ITMO20050056A1/it unknown
2006
- 2006-03-14 ES ES06765408T patent/ES2370942T5/es not_active Expired - Lifetime
- 2006-03-14 SI SI200631133T patent/SI1858930T2/sl unknown
- 2006-03-14 AT AT06765408T patent/ATE517127T1/de active
- 2006-03-14 PT PT06765408T patent/PT1858930E/pt unknown
- 2006-03-14 US US11/908,575 patent/US8759320B2/en active Active
- 2006-03-14 PL PL06765408.7T patent/PL1858930T5/pl unknown
- 2006-03-14 WO PCT/IB2006/000560 patent/WO2006111802A1/en not_active Ceased
- 2006-03-14 EP EP06765408.7A patent/EP1858930B2/en not_active Expired - Lifetime
- 2006-03-14 CA CA2601646A patent/CA2601646C/en not_active Expired - Lifetime
- 2006-03-14 DK DK06765408.7T patent/DK1858930T3/da active
2011
- 2011-09-27 CY CY20111100929T patent/CY1111885T1/el unknown
2014
- 2014-03-24 US US14/223,752 patent/US8993748B2/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
WO2006111802A9 (en)	2015-02-19
ES2370942T5 (es)	2024-11-08
ITMO20050056A1 (it)	2006-09-16
US8759320B2 (en)	2014-06-24
ES2370942T3 (es)	2011-12-23
EP1858930A1 (en)	2007-11-28
PT1858930E (pt)	2011-09-30
CA2601646C (en)	2012-11-27
US8993748B2 (en)	2015-03-31
EP1858930B1 (en)	2011-07-20
CA2601646A1 (en)	2006-10-26
US20080207558A1 (en)	2008-08-28
CY1111885T1 (el)	2015-11-04
SI1858930T2 (sl)	2024-07-31
US20140296508A1 (en)	2014-10-02
SI1858930T1 (sl)	2011-11-30
ATE517127T1 (de)	2011-08-15
PL1858930T5 (pl)	2024-12-02
WO2006111802A1 (en)	2006-10-26
DK1858930T3 (da)	2011-10-31
EP1858930B2 (en)	2024-04-03

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