PL1861387T3 - Pochodne benzoimidazolu i ich kompozycje farmaceutyczne - Google Patents
Pochodne benzoimidazolu i ich kompozycje farmaceutyczneInfo
- Publication number
- PL1861387T3 PL1861387T3 PL06715777T PL06715777T PL1861387T3 PL 1861387 T3 PL1861387 T3 PL 1861387T3 PL 06715777 T PL06715777 T PL 06715777T PL 06715777 T PL06715777 T PL 06715777T PL 1861387 T3 PL1861387 T3 PL 1861387T3
- Authority
- PL
- Poland
- Prior art keywords
- pharmaceutical compositions
- benzimidazole derivatives
- benzimidazole
- derivatives
- pharmaceutical
- Prior art date
Links
- 229940058303 antinematodal benzimidazole derivative Drugs 0.000 title 1
- 125000003785 benzimidazolyl group Chemical class N1=C(NC2=C1C=CC=C2)* 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/12—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/14—Radicals substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20050008183 | 2005-01-28 | ||
| KR1020050098349A KR20060087386A (ko) | 2005-01-28 | 2005-10-18 | 신규 벤조이미다졸 유도체 및 이를 함유하는 약제학적조성물 |
| PCT/KR2006/000324 WO2006080821A1 (en) | 2005-01-28 | 2006-01-27 | Novel benzoimidazole derivatives and pharmaceutical composition comprising the same |
| EP06715777.6A EP1861387B1 (en) | 2005-01-28 | 2006-01-27 | Benzimidazole derivatives and pharmaceutical compositions thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL1861387T3 true PL1861387T3 (pl) | 2014-08-29 |
Family
ID=36740776
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL06715777T PL1861387T3 (pl) | 2005-01-28 | 2006-01-27 | Pochodne benzoimidazolu i ich kompozycje farmaceutyczne |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1861387B1 (pl) |
| KR (1) | KR101099303B1 (pl) |
| AU (1) | AU2006209117B2 (pl) |
| CA (1) | CA2596013C (pl) |
| PL (1) | PL1861387T3 (pl) |
| WO (1) | WO2006080821A1 (pl) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007070173A2 (en) † | 2005-10-31 | 2007-06-21 | Merck & Co., Inc. | Cetp inhibitors |
| WO2007069565A1 (ja) * | 2005-12-12 | 2007-06-21 | Ono Pharmaceutical Co., Ltd. | 二環式複素環化合物 |
| CN101490037B (zh) | 2006-07-11 | 2013-06-12 | 大熊制药株式会社 | 联芳基苯并咪唑衍生物以及包含该衍生物的药物组合物 |
| KR20100115789A (ko) | 2008-02-04 | 2010-10-28 | 머큐리 테라퓨틱스, 인코포레이티드 | Ａｍｐｋ 조절자 |
| EP2264031B1 (en) * | 2008-04-18 | 2015-04-15 | Daewoong Pharmaceutical Co., Ltd. | A novel benzoxazine benzimidazole derivative, a pharmaceutical composition comprising the same, and a use thereof |
| SG174125A1 (en) * | 2009-04-02 | 2011-10-28 | Merck Serono Sa | Dihydroorotate dehydrogenase inhibitors |
| CN103180308B (zh) * | 2010-09-28 | 2015-04-08 | 大熊制药株式会社 | 制备苯并咪唑衍生物的方法 |
| WO2013042137A1 (en) * | 2011-09-19 | 2013-03-28 | Aurigene Discovery Technologies Limited | Bicyclic heterocycles as irak4 inhibitors |
| WO2013043521A1 (en) | 2011-09-22 | 2013-03-28 | Merck Sharp & Dohme Corp. | Pyrazolopyridyl compounds as aldosterone synthase inhibitors |
| JP6006010B2 (ja) * | 2012-06-14 | 2016-10-12 | ユー・ディー・シー アイルランド リミテッド | 化合物及び有機電界発光素子並びに該有機電界発光素子を用いた発光装置、表示装置及び照明装置 |
| GB201302927D0 (en) | 2013-02-20 | 2013-04-03 | Cancer Therapeutics Crc Pty Ltd | Compounds |
| GB201415573D0 (en) | 2014-09-03 | 2014-10-15 | Cancer Therapeutics Crc Pty Ltd | Compounds |
| EP3189041B1 (en) | 2014-09-03 | 2021-04-28 | Ctxt Pty Ltd | Tetrahydroisoquinoline derived prmt5-inhibitors |
| WO2016034671A1 (en) | 2014-09-03 | 2016-03-10 | Ctxt Pty Ltd | Aminoindane-, aminotetrahydronaphthalene- and aminobenzocyclobutane-derived prmt5-inhibitors |
| LT3209655T (lt) | 2014-10-24 | 2021-01-11 | Landos Biopharma, Inc. | Medicininiai preparatai į lantionino sintezę c panašaus baltymo 2 pagrindu |
| ES2875737T3 (es) | 2015-02-02 | 2021-11-11 | Kancera Ab | Derivados de 2-fenil-3H-imidazo[4,5-b]piridina útiles como inhibidores de la actividad tirosina quinasa de ROR1 de mamíferos |
| KR101653560B1 (ko) * | 2016-02-02 | 2016-09-12 | 한국화학연구원 | 신규한 화합물 또는 이의 약학적으로 허용가능한 염, 및 이를 유효성분으로 함유하는 인플루엔자 바이러스 감염으로 인한 질환의 예방 또는 치료용 약학적 조성물 |
| GB201604022D0 (en) | 2016-03-09 | 2016-04-20 | Ctxt Pty Ltd | Compounds |
| GB201604027D0 (en) | 2016-03-09 | 2016-04-20 | Ctxt Pty Ltd | Compounds |
| GB201604031D0 (en) | 2016-03-09 | 2016-04-20 | Ctxt Pty Ltd | Compounds |
| GB201604029D0 (en) | 2016-03-09 | 2016-04-20 | Ctxt Pty Ltd | Compounds |
| GB201604030D0 (en) | 2016-03-09 | 2016-04-20 | Ctxt Pty Ltd | Compounds |
| GB201604020D0 (en) | 2016-03-09 | 2016-04-20 | Ctxt Pty Ltd | Compounds |
| US11660303B2 (en) | 2016-07-11 | 2023-05-30 | Kancera Ab | 2-phenylimidazo[4,5-b]pyridin-7-amine derivates useful as inhibitors of mammalian tyrosine kinase ROR1 activity |
| KR102466810B1 (ko) | 2016-07-11 | 2022-11-11 | 칸세라 아베 | 포유류 티로신 키나제 ror1 활성의 저해제로서 유용한 2-페닐이미다조[4,5-b]피리딘-7-아민 유도체 |
| EP3562487B1 (en) | 2016-12-29 | 2023-11-29 | Ji Xing Pharmaceuticals Hong Kong Limited | Metalloenzyme inhibitor compounds |
| EP3562306B1 (en) | 2016-12-29 | 2025-02-26 | Ji Xing Pharmaceuticals Hong Kong Limited | Metalloenzyme inhibitor compounds |
| WO2019018562A1 (en) | 2017-07-19 | 2019-01-24 | Ideaya Biosciences, Inc. | AMIDO COMPOUND AS MODULATORS OF AHR |
| WO2019108418A1 (en) | 2017-11-30 | 2019-06-06 | Landos Biopharma, Inc. | Therapies with lanthionine c-like protein 2 ligands and cells prepared therewith |
| US11555035B2 (en) | 2017-12-22 | 2023-01-17 | Sumitomo Chemical Company, Limited | Heterocyclic compound and harmful arthropod-controlling agent containing same |
| CN114269383A (zh) | 2019-01-08 | 2022-04-01 | 菲斯生物制药公司 | 金属酶抑制剂化合物 |
| CN113748109B (zh) | 2019-12-20 | 2023-07-21 | 朗多生物制药股份有限公司 | 羊毛硫氨酸c样蛋白2配体、用所述配体制备的细胞以及使用所述配体的疗法 |
| EP4215526A4 (en) | 2020-09-18 | 2024-10-16 | Shanghai Pharmaceuticals Holding Co., Ltd. | HETEROCYCLIC CARBONYL COMPOUND AND ITS USE |
| EP4612139A1 (en) | 2022-11-03 | 2025-09-10 | Sentonix, Inc. | Selective ligands for tau aggregates |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1488286A (fr) * | 1966-04-01 | 1967-07-13 | Chimetron Sarl | Bis (benzimidazolyl-2) pyridines |
| IL133430A0 (en) * | 1997-08-05 | 2001-04-30 | Pfizer Prod Inc | 4-AMINOPYRROLE (3, 2-d) PYRIMIDINES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS |
| US6911462B2 (en) * | 1998-05-22 | 2005-06-28 | Avanir Pharmaceuticals | Benzimidazole compounds for regulating IgE |
| EP1391457B1 (de) * | 1998-11-03 | 2013-12-25 | AbbVie Deutschland GmbH & Co KG | Substituierte 2-Phenylbenzimidazole und deren Verwendung als PARP Inhibitoren |
| DE19920936A1 (de) * | 1999-05-07 | 2000-11-09 | Basf Ag | Heterozyklisch substituierte Benzimidazole, deren Herstellung und Anwendung |
| GB0017256D0 (en) * | 2000-07-13 | 2000-08-30 | Merck Sharp & Dohme | Therapeutic agents |
| DE60221866T2 (de) * | 2001-10-19 | 2008-05-29 | Ortho-Mcneil Pharmaceutical, Inc. | 2-PHENYL BENZIMIDAZOLE UND IMIDAZO-i4,5ö-PYRIDINE ALS CDS1/CHK2-INHIBITOREN UND ADJUVANTIEN IN DER CHEMOTHERAPIE ODER STRAHLUNGSTHERAPIE ZUR BEHANDLUNG VON KREBS |
| US6972281B2 (en) * | 2002-02-07 | 2005-12-06 | University Of Ottawa | Histogranin-like peptides and non-peptides, processes for their preparation and uses thereof |
| MXPA05000812A (es) * | 2002-07-31 | 2005-04-19 | Euro Celtique Sa | Bencimidazoles aril sustituidos y su uso como bloqueadores del canal de sodio. |
| AU2003301436A1 (en) * | 2002-10-17 | 2004-05-04 | Amgen Inc. | Benzimidazole derivatives and their use as vanilloid receptor ligands |
-
2006
- 2006-01-27 AU AU2006209117A patent/AU2006209117B2/en not_active Expired
- 2006-01-27 PL PL06715777T patent/PL1861387T3/pl unknown
- 2006-01-27 KR KR1020077018961A patent/KR101099303B1/ko not_active Expired - Lifetime
- 2006-01-27 EP EP06715777.6A patent/EP1861387B1/en not_active Expired - Lifetime
- 2006-01-27 WO PCT/KR2006/000324 patent/WO2006080821A1/en not_active Ceased
- 2006-01-27 CA CA2596013A patent/CA2596013C/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1861387B1 (en) | 2014-04-16 |
| CA2596013C (en) | 2012-06-05 |
| AU2006209117B2 (en) | 2009-12-10 |
| EP1861387A4 (en) | 2011-04-13 |
| AU2006209117A1 (en) | 2006-08-03 |
| EP1861387A1 (en) | 2007-12-05 |
| CA2596013A1 (en) | 2006-08-03 |
| KR101099303B1 (ko) | 2011-12-26 |
| WO2006080821A1 (en) | 2006-08-03 |
| KR20070113207A (ko) | 2007-11-28 |
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