PL1877073T3 - Niecytotoksyczne koniugaty białkowe - Google Patents

Niecytotoksyczne koniugaty białkowe

Info

Publication number
PL1877073T3
PL1877073T3 PL05810711T PL05810711T PL1877073T3 PL 1877073 T3 PL1877073 T3 PL 1877073T3 PL 05810711 T PL05810711 T PL 05810711T PL 05810711 T PL05810711 T PL 05810711T PL 1877073 T3 PL1877073 T3 PL 1877073T3
Authority
PL
Poland
Prior art keywords
protein conjugates
cytotoxic protein
cytotoxic
conjugates
protein
Prior art date
Application number
PL05810711T
Other languages
English (en)
Inventor
Keith Foster
John Chaddock
Charles Penn
K Roger Aoki
Joseph Francis
Lance Steward
Original Assignee
The Sec Dep For Health
Allergan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0426394A external-priority patent/GB0426394D0/en
Application filed by The Sec Dep For Health, Allergan Inc filed Critical The Sec Dep For Health
Publication of PL1877073T3 publication Critical patent/PL1877073T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Clostridium (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
PL05810711T 2004-12-01 2005-12-01 Niecytotoksyczne koniugaty białkowe PL1877073T3 (pl)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB0426394A GB0426394D0 (en) 2004-12-01 2004-12-01 Fusion proteins
GB0504966A GB0504966D0 (en) 2004-12-01 2005-03-10 Re-targeted toxin conjugates
GB0504964A GB0504964D0 (en) 2004-12-01 2005-03-10 Fusion proteins
EP05810711.1A EP1877073B1 (en) 2004-12-01 2005-12-01 Non-cytotoxic protein conjugates
PCT/GB2005/004598 WO2006059105A2 (en) 2004-12-01 2005-12-01 Non-cytotoxic Protein Conjugates

Publications (1)

Publication Number Publication Date
PL1877073T3 true PL1877073T3 (pl) 2014-03-31

Family

ID=35735383

Family Applications (1)

Application Number Title Priority Date Filing Date
PL05810711T PL1877073T3 (pl) 2004-12-01 2005-12-01 Niecytotoksyczne koniugaty białkowe

Country Status (5)

Country Link
EP (1) EP1877073B1 (pl)
AU (1) AU2005311098B2 (pl)
CA (1) CA2588292C (pl)
PL (1) PL1877073T3 (pl)
WO (1) WO2006059105A2 (pl)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7192596B2 (en) 1996-08-23 2007-03-20 The Health Protection Agency Ipsen Limited Recombinant toxin fragments
GB9617671D0 (en) * 1996-08-23 1996-10-02 Microbiological Res Authority Recombinant toxin fragments
HK1046020B (en) 1999-08-25 2007-05-11 Allergan, Inc. Activatable recombinant neurotoxins
US7138127B1 (en) 2000-01-19 2006-11-21 Allergan, Inc. Clostridial toxin derivatives and methods for treating pain
EP1982997B1 (en) 2004-09-01 2012-08-08 Allergan, Inc. Degradable clostridial toxins
US8399400B2 (en) 2004-12-01 2013-03-19 Syntaxin, Ltd. Fusion proteins
US8603779B2 (en) 2004-12-01 2013-12-10 Syntaxin, Ltd. Non-cytotoxic protein conjugates
GB0426394D0 (en) 2004-12-01 2005-01-05 Health Prot Agency Fusion proteins
GB0426397D0 (en) 2004-12-01 2005-01-05 Health Prot Agency Fusion proteins
US8512984B2 (en) 2004-12-01 2013-08-20 Syntaxin, Ltd. Non-cytotoxic protein conjugates
US8778634B2 (en) 2004-12-01 2014-07-15 Syntaxin, Ltd. Non-cytotoxic protein conjugates
US8021859B2 (en) 2005-03-15 2011-09-20 Allergan, Inc. Modified clostridial toxins with altered targeting capabilities for clostridial toxin target cells
CA2601592A1 (en) 2005-03-15 2006-09-28 Allergan, Inc. Modified clostridial toxins with enhanced targeting capabilities for endogenous clostridial toxin receptor systems
EP2377881B1 (en) 2005-09-19 2017-04-26 Allergan, Inc. Clostridial toxin activatable clostridial toxins
AU2011202225B2 (en) * 2005-12-01 2015-08-20 Allergan, Inc. Non-cytotoxic protein conjugates
GB0610867D0 (en) 2006-06-01 2006-07-12 Syntaxin Ltd Treatment of pain
GB0610868D0 (en) * 2006-06-01 2006-07-12 Syntaxin Ltd Treatment of pain
AU2007272515B2 (en) 2006-07-11 2013-09-26 Allergan, Inc. Modified clostridial toxins with enhanced translocation capabilities and altered targeting activity for clostridial toxin target cells
AU2007347781B2 (en) 2006-07-11 2013-10-03 Allergan, Inc. Modified clostridial toxins with enhanced translocation capability and enhanced targeting activity
AU2008316989A1 (en) 2007-10-23 2009-04-30 Allergan, Inc. Methods of treating urogenital-neurological disorders using modified clostridial toxins
JP5514399B2 (ja) * 2007-11-02 2014-06-04 国立大学法人 岡山大学 無機硫黄化合物加水分解酵素の製造方法
GB0725321D0 (en) * 2007-12-31 2008-02-06 Syntaxin Ltd Delivery vehicles
AU2009339292B2 (en) 2008-12-10 2016-01-21 Allergan, Inc. Clostridial toxin pharmaceutical compositions
SI3281953T1 (sl) 2009-03-13 2020-03-31 Allergan, Inc. Na imunosti temelječi testi za aktivnosti ponovno ciljane endopeptidaze
US20100303794A1 (en) 2009-05-29 2010-12-02 Allergan, Inc. Methods of Treating Urogenital-Neurological Disorders Using Glucagon Like Hormone Retargeted Endopepidases
US20100303757A1 (en) 2009-05-29 2010-12-02 Allergan, Inc. Methods of Treating Chronic Neurogenic Inflammation Using Interleukin Retargeted Endopepidases
AU2010281436B2 (en) 2009-07-27 2016-03-24 Tonix Pharma Limited. Methods for treatment of pain
CA2771298A1 (en) 2009-08-14 2011-02-17 Allergan, Inc. Methods of treating cancer using glucagon-like hormone retargeted endopeptidases
AU2010282289A1 (en) 2009-08-14 2012-03-15 Allergan, Inc. Methods of treating cancer using galanin retargeted endpeptidases
AU2010282285A1 (en) * 2009-08-14 2012-03-15 Allergan, Inc. Methods of treating cancer using opioid retargeted endpeptidases
AU2010282274A1 (en) 2009-08-14 2012-03-15 Allergan, Inc. Methods of treating cancer using growth factor retargeted endopeptidases
CA2771297A1 (en) 2009-08-14 2011-02-17 Allergan, Inc. Methods of treating cancer using neurotrophin retargeted endopeptidases
EP2464365A2 (en) 2009-08-14 2012-06-20 Allergan, Inc. Methods of treating cancer using tachykinin retargeted endopeptidases
WO2012112422A1 (en) 2011-02-14 2012-08-23 Allergan, Inc. Inhibiting aberrant blood vessel formation using growth factor retargeted endopeptidases
US20120207733A1 (en) 2011-02-14 2012-08-16 Allergan, Inc. Treating a Disease of Hyperproliferation Using Retargeted Endopeptidases
US20120207743A1 (en) 2011-02-14 2012-08-16 Allergan, Inc. Inhibiting Aberrant Blood Vessel Formation Using Retargeted Endopeptidases
WO2012112432A1 (en) 2011-02-14 2012-08-23 Allergan, Inc. Methods of inhibiting aberrant blood vessel formation using opioid retargeted endopeptidases
SI2776466T1 (sl) 2011-11-11 2017-12-29 Ucb Biopharma Sprl Protitelesa, ki se vežejo na albumin in njihovi vezavni fragmenti
US20140056870A1 (en) 2012-08-27 2014-02-27 Allergan, Inc. Fusion proteins
HRP20231438T1 (hr) 2015-01-07 2024-06-07 Tonix Pharma Limited Formulacije oksitocina koje sadrže magnezij i načini uporabe
MX2018012351A (es) 2016-04-12 2019-02-07 Trigemina Inc Formulaciones de oxitocina que contienen magnesio y metodos de uso.
IL308091B1 (en) 2016-09-13 2026-01-01 Allergan Inc Protein-free stabilized Clostridium toxin preparations
TW201814045A (zh) 2016-09-16 2018-04-16 英商艾普森生物製藥有限公司 製造雙鏈梭狀芽孢桿菌神經毒素之方法
EP3519430A1 (en) 2016-09-29 2019-08-07 Ipsen Biopharm Limited Hybrid neurotoxins
EP3312290A1 (en) 2016-10-18 2018-04-25 Ipsen Biopharm Limited Cellular vamp cleavage assay
GB202007441D0 (en) 2020-05-19 2020-07-01 Autolus Ltd Polypeptide
EP3915580A1 (en) 2020-05-29 2021-12-01 Numab Therapeutics AG Multispecific antibody
EP3988568A1 (en) 2020-10-21 2022-04-27 Numab Therapeutics AG Combination treatment
EP4255926A1 (en) 2020-12-07 2023-10-11 UCB Biopharma SRL Multi-specific antibodies and antibody combinations
KR20230166075A (ko) 2021-02-02 2023-12-06 누맙 세러퓨틱스 아게 Ror1 및 cd3에 대한 특이성을 가지는 다중 특이적 항체
EP4183800A1 (en) 2021-11-19 2023-05-24 Medizinische Hochschule Hannover Novel sars-cov-2 neutralizing antibodies

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9508204D0 (en) * 1995-04-21 1995-06-07 Speywood Lab Ltd A novel agent able to modify peripheral afferent function
US7192596B2 (en) * 1996-08-23 2007-03-20 The Health Protection Agency Ipsen Limited Recombinant toxin fragments
WO2003093293A2 (en) * 2002-04-29 2003-11-13 Saint Louis University Peptide antagonists of tgf-beta family members and therapeutic uses thereof
ITMI20022022A1 (it) * 2002-09-24 2004-03-25 Girolamo Calo' Analoghi di nocicettina.
GB0321344D0 (en) * 2003-09-11 2003-10-15 Health Prot Agency Re-targeted toxin conjugates

Also Published As

Publication number Publication date
EP1877073B1 (en) 2013-09-25
AU2005311098A1 (en) 2006-06-08
WO2006059105A2 (en) 2006-06-08
CA2588292C (en) 2019-01-15
CA2588292A1 (en) 2006-06-08
WO2006059105A3 (en) 2006-08-31
EP1877073A2 (en) 2008-01-16
WO2006059105A8 (en) 2007-11-08
AU2005311098B2 (en) 2011-08-11

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